# Sunday Riley Good Genes All-In-One Lactic Acid Treatment for mature skin

**Lovi Fit: High fit for mature skin.**
Normal Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/ca/p/sunday-riley/good-genes-all-in-one-lactic-acid-treatment/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Brand: [Sunday Riley](https://lovi.care/skincare/ca/brands/sunday-riley)
Category: [Exfoliants](https://lovi.care/skincare/ca/best/exfoliators)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for mature skin; a few products fit it even better.

## Why this fit

- Highly suitable for your normal skin, this treatment effectively addresses wrinkles and fine lines with lactic acid to promote cell turnover and squalane for emollient action.
- The inclusion of Aloe Barbadensis Leaf Extract and yeast extract further supports skin health and provides soothing benefits.
- The product is safe for your skin, with no risks of irritation due to the absence of harsh ingredients and the presence of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ca/p/sunday-riley/good-genes-all-in-one-lactic-acid-treatment/for/oily-skin): Superior
- [Dry skin](https://lovi.care/skincare/ca/p/sunday-riley/good-genes-all-in-one-lactic-acid-treatment/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/ca/p/sunday-riley/good-genes-all-in-one-lactic-acid-treatment/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/ca/p/sunday-riley/good-genes-all-in-one-lactic-acid-treatment/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/ca/p/sunday-riley/good-genes-all-in-one-lactic-acid-treatment/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/ca/p/sunday-riley/good-genes-all-in-one-lactic-acid-treatment/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/ca/p/sunday-riley/good-genes-all-in-one-lactic-acid-treatment/for/mature-skin): High (this page)
- [Dry sensitive skin](https://lovi.care/skincare/ca/p/sunday-riley/good-genes-all-in-one-lactic-acid-treatment/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/ca/p/sunday-riley/good-genes-all-in-one-lactic-acid-treatment/for/oily-acne-prone-skin): High

## Key ingredients

Lactic Acid, Licorice Root, Agave Tequilana Leaf Extract, Opuntia Tuna Fruit Extract, Arnica Montana Flower Extract

## What the research says

- PLLA-released lactate induces LTBP1 lactylation at lysine 752 via a KAT8-dependent mechanism, promoting collagen I and collagen III synthesis in fibroblasts for skin rejuvenation. ([International Journal of Biological Macromolecules, 2024](https://pubmed.ncbi.nlm.nih.gov/39102921/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Topical moisturizers improved skin barrier function and surface moisture, while a postbiotic moisturizer with yeast extract uniquely supported microbiome balance and modulated biomarkers of skin barrier, structure, and inflammation in participants and ex vivo explants exposed to environmental aggressors. ([Journal of Clinical Medicine, 2023](https://pubmed.ncbi.nlm.nih.gov/37763018/))
- Application of squalene/phosphotungstate calcium nanowires (Sql/PWC) oleogel on UVB-irradiated skin decreased epidermal thickness, increased dermal thickness, and promoted the expression of elastin, collagen, and skin barrier markers through antioxidant and anti-inflammatory activities. ([Journal of Nanobiotechnology, 2025](https://pubmed.ncbi.nlm.nih.gov/40001122/))
- Application of a cream containing lactic acid 12% and pramoxine HCl 1% significantly improved skin dryness, hydration, and itch compared with a nontreated control in 24 women with a history of dry itchy skin. ([Cutis, 2004](https://pubmed.ncbi.nlm.nih.gov/15027519/))
- Topical 12% ammonium lactate produced a significant sparing of epidermal and dermal atrophy induced by clobetasol propionate in human volunteers, without influencing the corticosteroid's bioavailability or antiinflammatory properties. ([Journal of the American Academy of Dermatology, 1992](https://pubmed.ncbi.nlm.nih.gov/1597538/))
- A lactic acid/ceramide lotion significantly improved skin moisturization and desquamation compared to no treatment in women with dry, rough skin on the anterior shins. ([The Journal of Clinical and Aesthetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/33178384/))
- Combining 755 nm alexandrite laser with topical licorice gel significantly reduces terminal hair counts compared to alexandrite laser with placebo in women with idiopathic hirsutism. ([Evidence-based Complementary and Alternative Medicine, 2015](https://pubmed.ncbi.nlm.nih.gov/26273313/))
- Licochalcone A activated Nrf2 signaling, elevated cytoprotective enzymes, increased the reduced-to-oxidized glutathione ratio, and decreased reactive oxygen species in human fibroblasts and neutrophils, while a LicA-rich licorice extract lowered UVA-induced oxidative processes in vivo. ([Experimental Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25381913/))
- Bioactive glycyrrhizic acid and oxymatrine ionic liquid self-assembled nanomicelles significantly promoted the transdermal permeation, subcutaneous retention, and anti-photoaging efficacy of palmitoyl pentapeptide-4 in cellular and animal models compared to unformulated peptide. ([Advanced Science, 2025](https://pubmed.ncbi.nlm.nih.gov/39783908/))
- Opuntia ficus-indica extract and its isorhamnetin-glucosyl-rhamnoside suppressed nitric oxide, COX-2, TNF-alpha, and IL-6 production in vitro and inhibited croton oil-induced ear edema in vivo. ([BioMed Research International, 2015](https://pubmed.ncbi.nlm.nih.gov/25821823/))
- Opuntia ficus-indica extract activated AHR-NRF2 signaling, inhibited reactive oxygen species generation, and upregulated filaggrin and loricrin expression in human keratinocytes. ([Journal of Medicinal Food, 2015](https://pubmed.ncbi.nlm.nih.gov/26061570/))
- Pre-treating normal human keratinocytes with an Opuntia ficus-indica cladode water extract protected against UVA-induced oxidative stress and apoptosis by inhibiting free radicals, lipid peroxidation, and GSH depletion. ([Bioorganic & Medicinal Chemistry Letters, 2017](https://pubmed.ncbi.nlm.nih.gov/29107540/))
- Gels containing 1% Arnica montana L. flower extract successfully enhanced the volume of the lips and face with a reduction of wrinkles in humans. ([International Journal of Cosmetic Science, 2023](https://pubmed.ncbi.nlm.nih.gov/35984685/))
- Topical application of Arnica montana ointment reduced the inflammatory response and oxidative damage in mice exposed to UVB radiation compared to untreated UVB-exposed skin. ([Cutaneous and Ocular Toxicology, 2020](https://pubmed.ncbi.nlm.nih.gov/32183539/))
- The protocol combining microcurrent with topical Arnica montana reduces inflammation, increases myofibroblast proliferation, and decreases macrophage presence in rats with skin lesions compared to controls. ([International Journal of Experimental Pathology, 2023](https://pubmed.ncbi.nlm.nih.gov/36752313/))

## What reviewers say

Based on a very large amount of data, this lactic acid treatment is highly praised for its ability to quickly exfoliate and retexturize skin, resulting in a noticeable glow and smoother skin texture. Users with dullness, hyperpigmentation, and fine lines report significant improvements in skin clarity and plumpness. Many find it gentle enough for sensitive or acne-prone skin, though the high price point is a frequent concern.

- Liked: Instant radiance (mostly mentioned)
- Liked: Smoothes texture (mostly mentioned)
- Disliked: High price point (mostly mentioned)
- Liked: Plumps fine lines (often mentioned)
- Liked: Gentle exfoliation (sometimes noted)
- Disliked: Distinctive scent (sometimes noted)
- Disliked: Mild tingling (rarely noted)

## How to apply

- Use this exfoliant product in your PM routine once a week to start, increasing frequency only if your skin tolerates it well. Always apply SPF the next morning to protect your skin.
- Apply this exfoliant product after cleansing and toner, but before your moisturizer. This ensures the best absorption into your skin.
- Gently press 2-3 drops of the exfoliant product into your face, avoiding any rubbing. Let it absorb for a minute before moving to the next step.
- Apply this exfoliant product on completely dry skin to get the best results. This helps your normal skin accept the product smoothly.
- Avoid the sensitive eye area while using this exfoliant product. Do a patch test before your first use and avoid mixing it with strong acids.
- Video: https://storage.pora.ai/028e5e793422a3b665c02ff502cf5a68.mp4

## Questions and answers

### What makes Sunday Riley Good Genes a great fit for mature skin?

Sunday Riley Good Genes is a great fit for mature skin because it uses lactic acid to smooth out wrinkles and fine lines, while squalane keeps your skin soft. It also helps calm your skin with soothing ingredients like aloe and licorice root.
Sources: [International Journal of Biological Macromolecules, 2024](https://pubmed.ncbi.nlm.nih.gov/39102921/), [Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/)

### Which ingredients make this exfoliant a good fit for mature skin?

This exfoliant is a great fit for mature skin because it uses lactic acid to promote cell renewal and squalane to keep the skin soft and smooth. It also includes aloe vera leaf extract and yeast extract to support overall skin health and calm the face.
Sources: [International Journal of Biological Macromolecules, 2024](https://pubmed.ncbi.nlm.nih.gov/39102921/), [Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/)

### What does Lactic Acid do for mature skin?

Lactic acid helps mature skin by boosting firmness and smoothing out rough texture through increased collagen production. It also helps lock in moisture and brightens dark spots for a more youthful appearance.
Sources: [International Journal of Biological Macromolecules, 2024](https://pubmed.ncbi.nlm.nih.gov/39102921/), [Frontiers in Medicine, 2021](https://pubmed.ncbi.nlm.nih.gov/33681250/)

### What does Licorice Root Extract do for mature skin?

Licorice root extract helps calm redness and may fade dark spots on mature skin while protecting against everyday skin stress. It works by slowing down pigment production and soothing irritation, which supports a more even and balanced complexion.
Sources: [Journal of Ethnopharmacology, 2025](https://pubmed.ncbi.nlm.nih.gov/40350048/), [Pigment Cell Research, 1998](https://pubmed.ncbi.nlm.nih.gov/9870547/)

### Where does this exfoliant go in a skincare routine for mature skin?

This treatment goes in the evening routine, after cleansing and before moisturizing. Start using it once a week, and carefully increase the frequency if your skin handles it well.

### Can I use this exfoliant with retinol, and in what order?

It is best to avoid using this exfoliant on the same night as your retinol to prevent irritation. Instead, alternate nights between the two or use retinol in the evening and this treatment on different days.

### How often should I use this exfoliant?

Start by using this treatment once a week in your evening routine, and carefully use it more often if your skin tolerates it well and shows good results. Acids help smooth wrinkles and fine lines by encouraging cell turnover, while soothing ingredients keep irritation unlikely.
Sources: [Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/32356917/), [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38406974/)

### Can this exfoliant clog pores, cause breakouts or purging for mature skin?

This treatment is unlikely to clog pores or cause breakouts on mature skin, and it is generally safe without irritation risks. Lactic acid helps clear dead surface cells to keep skin smooth, while squalane and soothing extracts help keep skin calm.
Sources: [Journal of Clinical Medicine, 2023](https://pubmed.ncbi.nlm.nih.gov/37763018/), [International Journal of Biological Macromolecules, 2024](https://pubmed.ncbi.nlm.nih.gov/39102921/)

### Is this exfoliant fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetearyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for mature skin

- [Dr.Althea Vitamin C Boosting Serum](https://lovi.care/skincare/ca/p/dr-althea/vitamin-c-boosting-serum/for/mature-skin) — High fit — CA$27.99 at Amazon
- [The Ordinary Matrixyl 10% + HA](https://lovi.care/skincare/ca/p/the-ordinary/matrixyl-10-ha/for/mature-skin) — High fit — CA$14.40 at Amazon
- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/ca/p/skin1004/probio-cica-intensive-ampoule/for/mature-skin) — High fit — CA$24.44 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/ca/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — CA$44.95 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/ca/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — CA$31.98 at Amazon
- Moisturizer: [Obagi Hydrate Luxe Moisture-Rich Cream](https://lovi.care/skincare/ca/p/obagi/hydrate-luxe/for/mature-skin) — Superior fit — CA$103.73 at Amazon

## Where to buy

- Sephora: CA$115.00 (https://www.sephora.com/ca/en/product/good-genes-all-in-one-lactic-acid-treatment-P422670?skuId=1929231)
Prices checked 10 Oct 2026.

## Ingredients

Water, Opuntia Tuna Fruit Extract, Cypripedium Pubescens Extract, Opuntia Vulgaris Leaf Extract, Agave Tequilana Leaf Extract, Arnica Montana Flower Extract, Aloe Barbadensis Leaf Extract, Yeast Extract, Leuconostoc Radish Root Ferment Filtrate, Caprylic Capric Triglyceride, Squalane, Lactic Acid, Ppg-12 Smdi Copolymer, Propanediol, Butylene Glycol, Stearic Acid, Dimethicone, Cetearyl Alcohol, Phenyl Trimethicone, Disiloxane, Ceteareth-20, Glyceryl Stearate, Peg-100 Stearate, Stearyl Glycyrrhetinate, Glycyrrhiza Glabra Root Extract, Cymbopogon Schoenanthus Oil Lemongrass Oil, Potassium Hydroxide, Phenoxyethanol, Xanthan Gum, Caprylyl Glycol, Chlorphenesin, Sodium Phytate
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/sunday-riley/good-genes-all-in-one-lactic-acid-treatment/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/sunday-riley/good-genes-all-in-one-lactic-acid-treatment/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/sunday-riley/good-genes-all-in-one-lactic-acid-treatment/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/sunday-riley/good-genes-all-in-one-lactic-acid-treatment/for/mature-skin
- France: https://lovi.care/skincare/fr/p/sunday-riley/good-genes-all-in-one-lactic-acid-treatment/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/sunday-riley/good-genes-all-in-one-lactic-acid-treatment/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/sunday-riley/good-genes-all-in-one-lactic-acid-treatment/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/sunday-riley/good-genes-all-in-one-lactic-acid-treatment/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/sunday-riley/good-genes-all-in-one-lactic-acid-treatment/for/mature-skin (this page)
- Australia: https://lovi.care/skincare/au/p/sunday-riley/good-genes-all-in-one-lactic-acid-treatment/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/sunday-riley/good-genes-all-in-one-lactic-acid-treatment/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/sunday-riley/good-genes-all-in-one-lactic-acid-treatment/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/sunday-riley/good-genes-all-in-one-lactic-acid-treatment/for/mature-skin