# SOME BY MI Yuja Niacin Blemish Care Serum for acne-prone skin

**Lovi Fit: High fit for acne-prone skin.**
Combination Skin Fit: High · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/ca/p/some-by-mi/yuja-niacin-blemish-care-serum/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Brand: [SOME BY MI](https://lovi.care/skincare/ca/brands/some-by-mi)
Category: [Serums and treatments](https://lovi.care/skincare/ca/best/serums)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for acne-prone skin; a few serums fit it even better.

## Why this fit

- This serum is highly suitable for your combination skin, as niacinamide helps regulate oil production and arbutin works to even out skin tone, addressing your concerns with acne and blemishes.
- The inclusion of sodium ascorbyl phosphate and panthenol further supports your skin by targeting inflammation and promoting a clearer complexion.
- The product has a favorable safety profile with no reported irritation risks for combination skin.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ca/p/some-by-mi/yuja-niacin-blemish-care-serum/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/ca/p/some-by-mi/yuja-niacin-blemish-care-serum/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/ca/p/some-by-mi/yuja-niacin-blemish-care-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/ca/p/some-by-mi/yuja-niacin-blemish-care-serum/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/ca/p/some-by-mi/yuja-niacin-blemish-care-serum/for/acne-prone-skin): High (this page)
- [Skin with dark spots](https://lovi.care/skincare/ca/p/some-by-mi/yuja-niacin-blemish-care-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/ca/p/some-by-mi/yuja-niacin-blemish-care-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/ca/p/some-by-mi/yuja-niacin-blemish-care-serum/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/ca/p/some-by-mi/yuja-niacin-blemish-care-serum/for/oily-acne-prone-skin): Superior

## Key ingredients

Yuja Extract, Niacinamide, Glutathione, Arbutin, Licorice Root Extract

## What the research says

- Topical combination of 5% sodium ascorbyl phosphate and 0.2% retinol reduced inflammatory acne lesions by 29.28% at 4 weeks and 63.10% at 8 weeks, outperforming either agent alone. ([International Journal of Cosmetic Science, 2009](https://pubmed.ncbi.nlm.nih.gov/19134126/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- A non-hydroquinone topical formulation (SKNB19) improved hyperpigmentation by 28.5% in patient self-assessment and 27% in independent reviewer assessment compared with 4% hydroquinone in 18 adult subjects, while showing significantly less irritation and better tolerability. ([Journal of Cosmetic Science, 2020](https://pubmed.ncbi.nlm.nih.gov/33022197/))
- Citrus junos callus extract decreased melanin content in melanocytes 1.85-fold compared with arbutin and promoted the proliferation of and procollagen synthesis by human fibroblasts by 154% and 176% at 500 μg/mL. ([Molecules, 2017](https://pubmed.ncbi.nlm.nih.gov/29232889/))
- Yuja-peel fractions (ethyl acetate, hexane, and butanol) inhibited MMP expression, induced moisturizing factors filaggrin and serine palmitoyltransferase, and decreased melanin content in UVB-irradiated HaCaT, HDF, and α-MSH-treated B16F10 cells. ([Antioxidants, 2022](https://pubmed.ncbi.nlm.nih.gov/36670913/))
- Upcycled low-molecular-weight anionic peptides from Citrus junos seeds protected UVR-irradiated keratinocytes and reconstructed skin tissue by scavenging reactive oxygen species, reducing paracrine cytokines, inhibiting melanin synthesis and TRP-2 expression, and increasing filaggrin, laminin-5, and type I collagen expression. ([International Journal of Molecular Sciences, 2024](https://pubmed.ncbi.nlm.nih.gov/38338991/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Glutathione amino acid precursors effectively increase cellular glutathione levels, reducing oxidative stress, ATP depletion, and DNA damage in human keratinocytes, clinical subjects, and ex vivo skin compared to controls. ([Journal of the European Academy of Dermatology and Venereology, 2024](https://pubmed.ncbi.nlm.nih.gov/38189670/))
- Topical oxidized glutathione significantly decreases the skin melanin index and improves moisture content, smoothness, wrinkle formation, and elasticity compared to placebo in healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/25378941/))
- Topical glutathione improves hyperpigmentation, reduces ultraviolet-induced erythema and wrinkles, decreases transepidermal water loss, and enhances antioxidant capacity. ([The Journal of Clinical and Aesthetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/41416233/))
- Encapsulation of alpha arbutin in an optimized ethosomal gel significantly improved skin melanin reduction, moisture content, and elasticity in human volunteers compared to conventional formulations. ([Heliyon, 2023](https://pubmed.ncbi.nlm.nih.gov/37681127/))
- Combining a home-based radiofrequency device and arbutin cream reduced mMASI scores by 25.6% and melanin index by 22.8% at 8 weeks compared to baseline in 38 participants. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/39918262/))
- Polyvinyl pyrrolidone-K90/Eudragit RL100 dissolving microneedle patches loaded with alpha-arbutin and resveratrol enhanced intradermal delivery by approximately 2.6 times compared to cream and slightly decreased the melanin index in human participants without causing skin irritation. ([Biomaterials Science, 2023](https://pubmed.ncbi.nlm.nih.gov/37183632/))
- Combining 755 nm alexandrite laser with topical licorice gel significantly reduces terminal hair counts compared to alexandrite laser with placebo in women with idiopathic hirsutism. ([Evidence-based Complementary and Alternative Medicine, 2015](https://pubmed.ncbi.nlm.nih.gov/26273313/))
- Licochalcone A activated Nrf2 signaling, elevated cytoprotective enzymes, increased the reduced-to-oxidized glutathione ratio, and decreased reactive oxygen species in human fibroblasts and neutrophils, while a LicA-rich licorice extract lowered UVA-induced oxidative processes in vivo. ([Experimental Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25381913/))
- Bioactive glycyrrhizic acid and oxymatrine ionic liquid self-assembled nanomicelles significantly promoted the transdermal permeation, subcutaneous retention, and anti-photoaging efficacy of palmitoyl pentapeptide-4 in cellular and animal models compared to unformulated peptide. ([Advanced Science, 2025](https://pubmed.ncbi.nlm.nih.gov/39783908/))

## What reviewers say

This serum is highly effective at brightening dull skin and fading dark spots and hyperpigmentation, with users frequently noting its lightweight, fast-absorbing texture and refreshing citrus scent. It is particularly well-suited for oily, combination, and sensitive skin types. Some users with dry skin found it necessary to layer with a moisturizer, and a small number reported minimal results or slight irritation.

- Liked: Lightweight, fast-absorbing (mostly mentioned)
- Liked: Brightens dull skin (often mentioned)
- Liked: Fades dark spots (often mentioned)
- Liked: Refreshing citrus scent (sometimes noted)
- Disliked: Minimal dramatic results (rarely noted)
- Disliked: Needs extra moisturizer (rarely noted)
- Disliked: Potential breakouts (rarely noted)

## How to apply

- Use your serum as part of your PM routine and start 3x/week before working up to daily use.
- Apply this treatment after cleansing and toner, and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the product on clean, dry skin to help manage your breakouts safely.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes SOME BY MI Yuja Niacin Blemish Care Serum a great fit for acne-prone skin?

SOME BY MI Yuja Niacin Blemish Care Serum is a great fit for acne-prone skin because niacinamide helps balance oil while sodium ascorbyl phosphate and panthenol work to calm redness and clear breakouts. It also features arbutin to help fade dark spots left behind by acne, and it has a safe formula that is unlikely to cause irritation.
Sources: [International Journal of Cosmetic Science, 2009](https://pubmed.ncbi.nlm.nih.gov/19134126/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Which ingredients make this serum a good fit for acne-prone skin?

This serum is a great fit because niacinamide helps regulate oil, while sodium ascorbyl phosphate and panthenol target inflammation for a clearer complexion. Arbutin also works to even out skin tone and fade blemishes, and the product has a very safe profile with no irritation risks.
Sources: [International Journal of Cosmetic Science, 2009](https://pubmed.ncbi.nlm.nih.gov/19134126/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### What does Yuja Extract do for acne-prone skin?

Yuja Extract helps support dry or irritated skin by boosting moisture and improving overall smoothness. It is unlikely to cause heavy greasy buildup, but acne-prone skin still needs ingredients that deeply clean pores and calm redness.
Sources: [Antioxidants, 2022](https://pubmed.ncbi.nlm.nih.gov/36670913/)

### What does Niacinamide do for acne-prone skin?

Niacinamide helps acne-prone skin by reducing both inflamed and uninflamed breakouts and calming redness. It is also very helpful for keeping oily skin balanced by cutting down on excess oil production, and it is well tolerated by most people.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38299457/), [Cureus, 2024](https://pubmed.ncbi.nlm.nih.gov/38725769/)

### Where does this serum go in a skincare routine for acne-prone skin?

This serum goes in your evening routine, applied after cleansing and before your moisturizer. Using it at night helps keep things simple and keeps your skin safe from the sun while the active ingredients work.

### Can I use this serum with retinol, and in what order?

Yes, you can use this serum with retinol, applying this treatment first and following with your retinol after it absorbs. This product is unlikely to cause irritation on acne-prone skin, helping you layer active ingredients safely while targeting breakouts and uneven tone.

### How often should I use this serum?

This serum is a great fit for your acne-prone skin and is generally used in your evening routine. It has a very safe profile with little to no risk of irritation, helping to calm inflammation and clear blemishes smoothly.
Sources: [International Journal of Cosmetic Science, 2009](https://pubmed.ncbi.nlm.nih.gov/19134126/)

### Can this serum clog pores, cause breakouts or purging for acne-prone skin?

This serum is a great fit for acne-prone skin because niacinamide helps balance oil and sodium ascorbyl phosphate targets inflammation to keep skin clear. It has a very safe profile and is unlikely to clog pores, with only a low chance of causing breakouts for this skin type.
Sources: [International Journal of Cosmetic Science, 2009](https://pubmed.ncbi.nlm.nih.gov/19134126/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Is this serum fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (limonene and linalool).

## Alternatives for acne-prone skin

- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/ca/p/skin1004/probio-cica-intensive-ampoule/for/acne-prone-skin) — High fit — CA$24.44 at Amazon
- [Dr.Althea Vitamin C Boosting Serum](https://lovi.care/skincare/ca/p/dr-althea/vitamin-c-boosting-serum/for/acne-prone-skin) — High fit — CA$27.99 at Amazon
- [ANUA PEACH 70% NIACINAMIDE SERUM](https://lovi.care/skincare/ca/p/anua/peach-70-niacinamide-serum/for/acne-prone-skin) — High fit — CA$33.50 at Amazon

## Pairs well with

- Cleanser: [B.LAB Matcha Hydrating Foam Cleanser](https://lovi.care/skincare/ca/p/b-lab/matcha-hydrating-foam-cleanser/for/acne-prone-skin) — Superior fit — CA$22.95 at Amazon
- Hydrating Toner: [Paula's Choice Resist Advanced Replenishing Toner](https://lovi.care/skincare/ca/p/paula-s-choice/advanced-replenishing-toner/for/acne-prone-skin) — Superior fit — CA$41.00 at Amazon
- Moisturizer: [CeraVe CeraVe PM Facial Moisturizing Lotion](https://lovi.care/skincare/ca/p/cerave/pm-facial-moisturizing-lotion/for/acne-prone-skin) — Superior fit — CA$20.96 at Amazon

## Where to buy

- Amazon.ca: CA$32.00 (https://www.amazon.ca/dp/B07Z4M7HZV?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Citrus Junos Fruit Extract, Niacinamide, Butylene Glycol, 1,2-Hexanediol, Propanediol, C12-14 Pareth-12, Water, Trehalose, C12-14 Pareth-7, Carbomer, Citrus Junos Peel Oil, Tromethamine, Ethylhexylglycerin, Adenosine, Coptis Chinensis Root Extract, Glycyrrhiza Glabra Root Extract Licorice Root Extract, Agrimonia Eupatoria Extract, Camellia Sinensis Leaf Extract, Cellulose Gum, Chamaecyparis Obtusa Leaf Extract, Glycerin, Disodium Edta, Arbutin, Perilla Frutescens Leaf Extract, Xylitylglucoside, Anhydroxylitol, Xylitol, Saussurea Involucrata Extract, Glucose, Hydrogenated Lecithin, Peppermint Extract, Polyglyceryl-10 Stearate, Panthenol, Glutathione, Sodium Ascorbyl Phosphate, Maltodextrin, Persea Gratissima Fruit Extract Avocado Fruit Extract, Pancratium Maritimum Extract, Folic Acid, Biotin, Pyridoxine, Tocopherol, Cyanocobalamin, Linoleic Acid, Thiamine Hcl, Beta-Carotene, Riboflavin, Inositol, Limonene, Linalool
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/some-by-mi/yuja-niacin-blemish-care-serum/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/some-by-mi/yuja-niacin-blemish-care-serum/for/acne-prone-skin
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