# SkinCeuticals Tripeptide-R Neck Repair for sensitive skin

**Lovi Fit: Low fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: High · Safety: Concerning.

Page: https://lovi.care/skincare/ca/p/skinceuticals/tripeptide-r-neck-repair/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Brand: [SkinCeuticals](https://lovi.care/skincare/ca/brands/skinceuticals)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A weak match for sensitive skin; the products alongside fit it better.

## Why this fit

- Offers moderate benefits for redness and irritation due to the presence of retinol and lavender oil in concentrations that may exacerbate sensitivity, while glycerin provides humectant action suitable for normal skin.
- The retinol and tripeptide-r offer excellent wrinkle reduction for the neck, though the concentration of retinol may be too potent for your sensitive skin's redness concerns.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ca/p/skinceuticals/tripeptide-r-neck-repair/for/oily-skin): Low
- [Dry skin](https://lovi.care/skincare/ca/p/skinceuticals/tripeptide-r-neck-repair/for/dry-skin): Caution
- [Combination skin](https://lovi.care/skincare/ca/p/skinceuticals/tripeptide-r-neck-repair/for/combination-skin): Low
- [Sensitive skin](https://lovi.care/skincare/ca/p/skinceuticals/tripeptide-r-neck-repair/for/sensitive-skin): Low (this page)
- [Acne-prone skin](https://lovi.care/skincare/ca/p/skinceuticals/tripeptide-r-neck-repair/for/acne-prone-skin): Low
- [Skin with dark spots](https://lovi.care/skincare/ca/p/skinceuticals/tripeptide-r-neck-repair/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/ca/p/skinceuticals/tripeptide-r-neck-repair/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/ca/p/skinceuticals/tripeptide-r-neck-repair/for/dry-sensitive-skin): Caution
- [Oily acne-prone skin](https://lovi.care/skincare/ca/p/skinceuticals/tripeptide-r-neck-repair/for/oily-acne-prone-skin): Low

## Key ingredients

Tripeptides, Retinol, Hydrolyzed Rice Protein, Glycerin, Dimethicone

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging. ([The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/))
- Topical 0.4% retinol significantly increased epidermal thickness, dermal vascularity, and extracellular matrix production by stimulating keratinocyte proliferation, endothelial cell proliferation, and fibroblast activation in naturally aged human skin compared to vehicle. ([International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/))
- Silicone particles encapsulating retinol increased its half-life by 9-fold and yielded 12-23% lower skin irritation in human subjects compared to Microsponge particles while maintaining biological activity. ([Journal of Controlled Release, 2018](https://pubmed.ncbi.nlm.nih.gov/29604311/))
- Topical stabilized retinol treatment induced HAS gene expression and increased hyaluronic acid production in human skin in vitro, ex vivo, and in vivo compared to vehicle. ([Archives of Dermatological Research, 2017](https://pubmed.ncbi.nlm.nih.gov/28247017/))
- Topical application of all-trans-retinol induced epidermal thickening and increased retinoid binding protein expression similar to all-trans-retinoic acid in normal human skin, but without causing significant erythema or measurable retinoic acid levels. ([The Journal of Investigative Dermatology, 1995](https://pubmed.ncbi.nlm.nih.gov/7561157/))
- Rice protein hydrolysate and its characteristic peptides Leu-Leu-Lys, Leu-Pro-Lys, and pyroGlu-Lys reduced melanin content, tyrosinase activity, and ROS production in UVB-induced human epidermal melanocyte PIG1 cells by regulating the JNK/Β-Trcp/NFΗB-p65/MITF signaling pathway and lowering TRP-1 and TRP-2 expression. ([Food & Function, 2020](https://pubmed.ncbi.nlm.nih.gov/32955075/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Wearing an N95 mask alone compared to using dimethicone cream or hydrocolloid dressing caused more adverse skin reactions among 73 military health care workers, with no significant differences in fit test failure rates between groups. ([Military Medicine, 2024](https://pubmed.ncbi.nlm.nih.gov/38771104/))
- A dimethicone skin protectant lotion significantly decreased visual scoring and transepidermal water loss compared to vehicle control and SLS-only treated sites in 12 healthy humans exposed to sodium lauryl sulfate. ([Skin Research and Technology, 2000](https://pubmed.ncbi.nlm.nih.gov/11428946/))
- Treatment with a moisturizer containing dimethicone and glycerine increased epidermal thickness by 0.019 mm, improved barrier function by decreasing transepidermal water loss by 13%, decreased melanin intensity, and induced keratins 6 and 16 in fifteen women with moderately photoaged forearms. ([Clinical and Experimental Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17137484/))

## Why other products fit sensitive skin better

- Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging. ([The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/))

## What reviewers say

Users frequently report visible improvements in skin texture and firmness, specifically noting a reduction in "tech neck" lines and crepiness after consistent use. A significant minority experience adverse reactions typical of retinol, such as redness, itching, and rashes, emphasizing the need for a gradual introduction to the routine.

- Liked: Smoother skin (often mentioned)
- Liked: Firmer appearance (sometimes noted)
- Liked: Pleasant application (sometimes noted)
- Liked: Reduced neck lines (sometimes noted)
- Disliked: Skin irritation (sometimes noted)
- Disliked: Adverse reaction (rarely noted)
- Disliked: Dryness and peeling (rarely noted)
- Disliked: High price point (rarely noted)

## Questions and answers

### Why is SkinCeuticals Tripeptide-R Neck Repair a weak match for sensitive skin?

This neck cream may be too potent for sensitive skin because it contains retinol and lavender oil at levels that can aggravate redness and irritation. To fit this skin type safely, a product of this type needs soothing and calming ingredients along with gentle hydrators that support the skin barrier without causing flare-ups.
Sources: [International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/)

### Which ingredients make this cream a poor fit for sensitive skin?

This cream is a weak match for sensitive skin because the retinol and lavender oil are present in concentrations that may exacerbate sensitivity, redness, and irritation. A product of this type needs gentle, soothing, and hydrating ingredients like plant extracts and barrier-supporting lipids, without harsh exfoliants or potential irritants.
Sources: [International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/)

### What do Tripeptides do for sensitive skin?

Collagen tripeptide F helps calm sensitive skin by improving dryness, roughness, and irritation. It also helps make skin feel smoother and look less red with regular use.
Sources: [International Journal of Cosmetic Science, 2009](https://pubmed.ncbi.nlm.nih.gov/19496838/)

### What does Retinol do for sensitive skin?

Retinol is generally too harsh for sensitive skin and may cause stinging, scaling, and irritation. A product for this skin needs gentle ingredients that smooth and calm without causing redness.
Sources: [The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/), [Toxicology Letters, 2003](https://pubmed.ncbi.nlm.nih.gov/14615068/)

### Where does this cream go in a skincare routine for sensitive skin?

This neck cream is a treatment step for the evening routine, though the retinol in it may trigger redness and irritation on sensitive skin. A product of this type for sensitive skin needs soothing ingredients and gentle hydrators like glycerin and ceramides to keep the skin calm and soft.
Sources: [International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/)

### Can I use this cream with glycolic acid, and in what order?

This cream is a weak match for your sensitive skin because its retinol and essential oils may trigger redness and irritation. To use this alongside glycolic acid, apply your glycolic acid first, let it absorb fully, and then follow with this treatment on nights when your skin feels calm and resilient. A product of this type needs soothing, barrier-repairing ingredients like ceramides and gentle hydrators to keep sensitive skin comfortable while using strong active ingredients.

### How often should I use this cream?

This neck cream is unlikely to be a good fit for your sensitive skin because its retinol and lavender oil may trigger redness and irritation. A product of this type needs soothing ingredients and gentle, lower-strength active ingredients to keep sensitive skin calm and smooth.

### Can this cream clog pores, cause breakouts or purging for sensitive skin?

This cream is unlikely to clog pores, but the retinol inside may cause some peeling or temporary purging on sensitive skin. A product for this skin needs soothing ingredients and gentle hydrators to keep the skin calm and soft.
Sources: [International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/)

### Is this cream fragrance-free and alcohol-free?

It contains fragrance (linalool) and drying alcohol (alcohol).

## Alternatives for sensitive skin

- [Tula Skincare Pro-Glycolic 10% Resurfacing Toner](https://lovi.care/skincare/ca/p/tula/secret-solution-pro-glycolic-10-resurfacing-toner/for/sensitive-skin) — Superior fit — CA$137.73 at Amazon
- [The Ordinary Glycolic Acid 7% Toning Solution](https://lovi.care/skincare/ca/p/the-ordinary/glycolic-acid-7-toning-solution/for/sensitive-skin) — Superior fit — CA$15.80 at Amazon
- [I'm From Mugwort Mask](https://lovi.care/skincare/ca/p/i-m-from/mugwort-mask/for/sensitive-skin) — High fit — CA$35.50 at Amazon

## Routine for sensitive skin

### AM

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/ca/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — CA$44.95 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/ca/p/clarins/soothing-toning-lotion/for/sensitive-skin) — Superior fit — CA$49.00 at Amazon
- Moisturizer with Sun Protection: [Torriden DIVE-IN Mild Sunscreen](https://lovi.care/skincare/ca/p/torriden/dive-in-mild-sunscreen/for/sensitive-skin) — Superior fit — CA$27.34 at Amazon

### PM

- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/ca/p/missha/ultra-hyalon-cleansing-cream/for/sensitive-skin) — Superior fit — CA$17.99 at Amazon
- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/ca/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — CA$44.95 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/ca/p/clarins/soothing-toning-lotion/for/sensitive-skin) — Superior fit — CA$49.00 at Amazon
- Serum or Treatment: [Purito Centella Unscented Serum](https://lovi.care/skincare/ca/p/purito/centella-unscented-serum/for/sensitive-skin) — Superior fit — CA$23.25 at Amazon
- Moisturizer: [SKIN1004 Madagascar Centella Probio-Cica Enrich Cream](https://lovi.care/skincare/ca/p/skin1004/madagascar-centella-probio-cica-enrich-cream/for/sensitive-skin) — Superior fit — CA$30.98 at Amazon

### Weekly

- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/ca/p/missha/ultra-hyalon-cleansing-cream/for/sensitive-skin) — Superior fit — CA$17.99 at Amazon
- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/ca/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — CA$44.95 at Amazon
- Enzyme Powder: [Dr. Barbara Sturm Enzyme Cleanser](https://lovi.care/skincare/ca/p/dr-barbara-sturm/enzyme-cleanser/for/sensitive-skin) — High fit — CA$157.17 at Amazon
- Nourishing Mask: [Anua Heartleaf 77% Soothing Sheet Mask](https://lovi.care/skincare/ca/p/anua/heartleaf-77-soothing-sheet-mask/for/sensitive-skin) — Superior fit — CA$10.00 at Amazon
- Serum or Treatment: [Purito Centella Unscented Serum](https://lovi.care/skincare/ca/p/purito/centella-unscented-serum/for/sensitive-skin) — Superior fit — CA$23.25 at Amazon
- Moisturizer: [SKIN1004 Madagascar Centella Probio-Cica Enrich Cream](https://lovi.care/skincare/ca/p/skin1004/madagascar-centella-probio-cica-enrich-cream/for/sensitive-skin) — Superior fit — CA$30.98 at Amazon

## Where to buy

No store in Canada has a checked price for this product, so the page shows none.

## Ingredients

Water, Glycerin, Dimethicone, Hydrogenated Polyisobutene, Vinyl Dimethicone Methicone Silsesquioxane Crosspolymer, Methyl Methacrylate Crosspolymer, Ammonium Polyacryloyldimethyl Taurate, Helianthus Annuus Sunflower Seed Oil, Myristyl Myristate, Allyl Methacrylates Crosspolymer, Sodium Hydroxide, Potassium Cetyl Phosphate, Glyceryl Stearate Se, Capryloyl Glycine, Caprylyl Glycol, Silica Silylate, Pentylene Glycol, Stearic Acid, Hydrolyzed Rice Protein, Palmitic Acid, Retinol, Polysorbate 20, Coco-Glucoside, Argilla Magnesium Aluminum Silicate, Xanthan Gum, Alcohol, Bht, Sodium Citrate, Myristic Acid, Lavandula Angustifolia Lavender Oil, Rosmarinus Officinalis Rosemary Oil Leaf, Mentha Piperita Peppermint Oil, Glaucine, Citric Acid, Linalool, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Magnesium Chloride, Tocopherol, Propyl Gallate, Biotin
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/skinceuticals/tripeptide-r-neck-repair/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/skinceuticals/tripeptide-r-neck-repair/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/skinceuticals/tripeptide-r-neck-repair/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/skinceuticals/tripeptide-r-neck-repair/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/skinceuticals/tripeptide-r-neck-repair/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/skinceuticals/tripeptide-r-neck-repair/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/skinceuticals/tripeptide-r-neck-repair/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/skinceuticals/tripeptide-r-neck-repair/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/skinceuticals/tripeptide-r-neck-repair/for/sensitive-skin (this page)
- Australia: https://lovi.care/skincare/au/p/skinceuticals/tripeptide-r-neck-repair/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/skinceuticals/tripeptide-r-neck-repair/for/sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/skinceuticals/tripeptide-r-neck-repair/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/skinceuticals/tripeptide-r-neck-repair/for/sensitive-skin