# SkinCeuticals A.G.E. Interrupter for sensitive skin

**Lovi Fit: Warning fit for sensitive skin.**
Normal Skin Fit: Average · Effectiveness: Average · Safety: Warning.

Page: https://lovi.care/skincare/ca/p/skinceuticals/a-g-e-interrupter/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Brand: [SkinCeuticals](https://lovi.care/skincare/ca/brands/skinceuticals)
Category: [Serums and treatments](https://lovi.care/skincare/ca/best/serums)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A poor match for sensitive skin; the serums alongside fit it better.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ca/p/skinceuticals/a-g-e-interrupter/for/oily-skin): Warning
- [Dry skin](https://lovi.care/skincare/ca/p/skinceuticals/a-g-e-interrupter/for/dry-skin): Warning
- [Combination skin](https://lovi.care/skincare/ca/p/skinceuticals/a-g-e-interrupter/for/combination-skin): Warning
- [Sensitive skin](https://lovi.care/skincare/ca/p/skinceuticals/a-g-e-interrupter/for/sensitive-skin): Warning (this page)
- [Acne-prone skin](https://lovi.care/skincare/ca/p/skinceuticals/a-g-e-interrupter/for/acne-prone-skin): Warning
- [Skin with dark spots](https://lovi.care/skincare/ca/p/skinceuticals/a-g-e-interrupter/for/dark-spots): Warning
- [Mature skin](https://lovi.care/skincare/ca/p/skinceuticals/a-g-e-interrupter/for/mature-skin): Warning
- [Dry sensitive skin](https://lovi.care/skincare/ca/p/skinceuticals/a-g-e-interrupter/for/dry-sensitive-skin): Warning
- [Oily acne-prone skin](https://lovi.care/skincare/ca/p/skinceuticals/a-g-e-interrupter/for/oily-acne-prone-skin): Warning

## Key ingredients

Hydroxypropyl Tetrahydropyrantriol, Proxylane, Salicyloyl Phytosphingosine, Glycerin, Vaccinium Myrtillus Extract

## What the research says

- Application of a hydroxypropyl tetrahydropyrantriol and niacinamide formula following nonablative fractional laser treatment demonstrated comparable healing benefits to clinical control and significant improvements in fine lines, crow's feet wrinkles, skin roughness, and overall healthy appearance over 56 days in White and Northeast Asian panels. ([The Journal of Clinical and Aesthetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/41647767/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Fermented bilberry extract improved wrinkle depth, skin smoothness, roughness, firmness, elasticity, antioxidant capacity, and complexion evenness compared to a placebo in 66 subjects over 84 days. ([Nutrients, 2024](https://pubmed.ncbi.nlm.nih.gov/39064646/))
- Topical application of oil-in-water creams containing wild bilberry leaves extract and seeds oil produced significant beneficial effects on the skin of healthy human volunteers. ([Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/33809607/))
- Bilberry fruit extract incorporated into chitosan-based hydrogels demonstrated antioxidant, anti-hyaluronidase, and anti-tyrosinase activities, supporting their potential use in topical anti-aging preparations. ([Antioxidants, 2024](https://pubmed.ncbi.nlm.nih.gov/38247529/))

## What reviewers say

Based on a very large amount of data, this cream is highly effective for mature and thinning skin, with users frequently reporting significant reduction in deep wrinkles and improved skin texture, leading to a plumper, firmer appearance. It is also noted for providing deep hydration. However, a considerable number of users express concerns about the high price point, and some find the texture and finish of the reformulated product less desirable than the original, with occasional complaints about packaging and scent.

- Disliked: High price point (mostly mentioned)
- Liked: Improves skin texture (often mentioned)
- Liked: Reduces deep wrinkles (often mentioned)
- Liked: Deeply hydrating (sometimes noted)
- Liked: Plumps and firms (sometimes noted)
- Disliked: Texture/finish issues (sometimes noted)
- Disliked: Jar packaging (rarely noted)
- Disliked: Scent dislike (rarely noted)

## How to apply

- Use your serum in the PM routine, starting 3 times a week before building up to daily use if your skin is happy.
- Apply the serum after cleansing and toning, but before putting on your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏱ for it to soak in.
- Since your skin is sensitive and easily irritated, apply the serum on completely dry skin to help keep it calm.
- Always do a patch test before your first use and avoid getting the serum too close to your eyes .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### Why does Lovi advise against SkinCeuticals A.G.E. Interrupter for sensitive skin?

This treatment is a poor match because sensitive skin needs products that calm redness and irritation without risks of irritation, using soothing ingredients like niacinamide or snail secretion filtrate.

### Which ingredients make this cream a poor fit for sensitive skin?

This cream is a poor fit for sensitive skin because it lacks soothing ingredients that calm redness and irritation without causing adverse reactions. Sensitive skin needs treatments with gentle, hydrating, and skin-repairing components like niacinamide and antioxidants to maintain comfort and health.

### What does Proxylane do for sensitive skin?

Proxylane helps support the deeper layers of the skin, making it feel firmer and look smoother. It may improve overall skin structure, though sensitive skin needs soothing and strengthening ingredients like niacinamide or ceramides to stay calm and comfortable.
Sources: [European Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18086587/), [European Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18474459/)

### Where does this cream go in a skincare routine for sensitive skin?

This treatment is a poor match for sensitive skin, so Lovi advises against using it on this skin type. Sensitive skin needs gentle, soothing ingredients like glycerin and calming plant extracts that help keep skin calm without causing irritation.

### Can I use this cream with retinol, and in what order?

This treatment is a poor fit for sensitive skin, so using it alongside retinol may cause extra irritation and redness. Sensitive skin needs gentle, calming ingredients like glycerin and soothing plant extracts rather than strong anti-aging formulas.

### How often should I use this cream?

It is best to avoid using this cream on sensitive skin, as it is a poor match and may cause irritation. Sensitive skin needs gentle, calming ingredients and soothing hydrators instead of active anti-aging treatments.

### Can this cream clog pores, cause breakouts or purging for sensitive skin?

This cream is unlikely to cause purging since it does not contain active ingredients that speed up skin shedding, but it may clog pores or trigger breakouts on sensitive skin due to its rich, heavy texture and waxes. Sensitive skin needs lightweight, calming formulas with soothing ingredients like aloe and niacinamide instead of heavy anti-aging creams.

### Is this cream fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (parfum and coumarin).

## Alternatives for sensitive skin

- [COSRX The Vitamin C 23 Serum](https://lovi.care/skincare/ca/p/cosrx/the-vitamin-c-23-serum/for/sensitive-skin) — High fit — CA$33.98 at Amazon
- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/ca/p/skin1004/probio-cica-intensive-ampoule/for/sensitive-skin) — High fit — CA$24.44 at Amazon
- [The Ordinary Matrixyl 10% + HA](https://lovi.care/skincare/ca/p/the-ordinary/matrixyl-10-ha/for/sensitive-skin) — High fit — CA$14.40 at Amazon

## Routine for sensitive skin

### AM

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/ca/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — CA$44.95 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/ca/p/clarins/soothing-toning-lotion/for/sensitive-skin) — Superior fit — CA$49.00 at Amazon
- Moisturizer with Sun Protection: [Torriden DIVE-IN Mild Sunscreen](https://lovi.care/skincare/ca/p/torriden/dive-in-mild-sunscreen/for/sensitive-skin) — Superior fit — CA$27.34 at Amazon

### PM

- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/ca/p/missha/ultra-hyalon-cleansing-cream/for/sensitive-skin) — Superior fit — CA$17.99 at Amazon
- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/ca/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — CA$44.95 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/ca/p/clarins/soothing-toning-lotion/for/sensitive-skin) — Superior fit — CA$49.00 at Amazon
- Serum or Treatment: [Purito Centella Unscented Serum](https://lovi.care/skincare/ca/p/purito/centella-unscented-serum/for/sensitive-skin) — Superior fit — CA$23.25 at Amazon
- Moisturizer: [SKIN1004 Madagascar Centella Probio-Cica Enrich Cream](https://lovi.care/skincare/ca/p/skin1004/madagascar-centella-probio-cica-enrich-cream/for/sensitive-skin) — Superior fit — CA$30.98 at Amazon

### Weekly

- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/ca/p/missha/ultra-hyalon-cleansing-cream/for/sensitive-skin) — Superior fit — CA$17.99 at Amazon
- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/ca/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — CA$44.95 at Amazon
- Enzyme Powder: [Dr. Barbara Sturm Enzyme Cleanser](https://lovi.care/skincare/ca/p/dr-barbara-sturm/enzyme-cleanser/for/sensitive-skin) — High fit — CA$157.17 at Amazon
- Nourishing Mask: [Anua Heartleaf 77% Soothing Sheet Mask](https://lovi.care/skincare/ca/p/anua/heartleaf-77-soothing-sheet-mask/for/sensitive-skin) — Superior fit — CA$10.00 at Amazon
- Serum or Treatment: [Purito Centella Unscented Serum](https://lovi.care/skincare/ca/p/purito/centella-unscented-serum/for/sensitive-skin) — Superior fit — CA$23.25 at Amazon
- Moisturizer: [SKIN1004 Madagascar Centella Probio-Cica Enrich Cream](https://lovi.care/skincare/ca/p/skin1004/madagascar-centella-probio-cica-enrich-cream/for/sensitive-skin) — Superior fit — CA$30.98 at Amazon

## Where to buy

- Amazon.ca: CA$323.56 (https://www.amazon.ca/dp/B0041PDUY8?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
Prices checked 2 Nov 2026.

## Ingredients

Water, Propylene Glycol, Dimethicone, Hydroxypropyl Tetrahydropyrantriol, Cyclohexasiloxane, Isohexadecane, Glycerin, Synthetic Wax, Peg-10 15 Crosspolymer, Aluminum Octenylsuccinate Starch, Bismuth Oxychloride, Phenoxyethanol, Magnesium Sulfate, Ethylhexyl Hydroxystearate, Salicyloyl Phytosphingosine, Acrylates Copolymer, Methylparaben, Ethylparaben, Disodium Edta, Vaccinium Myrtillus Extract, Vaccinium Myrtillus Fruit Extract, Parfum, Butylphenyl Methylpropional, Coumarin
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/skinceuticals/a-g-e-interrupter/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/skinceuticals/a-g-e-interrupter/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/skinceuticals/a-g-e-interrupter/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/skinceuticals/a-g-e-interrupter/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/skinceuticals/a-g-e-interrupter/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/skinceuticals/a-g-e-interrupter/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/skinceuticals/a-g-e-interrupter/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/skinceuticals/a-g-e-interrupter/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/skinceuticals/a-g-e-interrupter/for/sensitive-skin (this page)
- Australia: https://lovi.care/skincare/au/p/skinceuticals/a-g-e-interrupter/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/skinceuticals/a-g-e-interrupter/for/sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/skinceuticals/a-g-e-interrupter/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/skinceuticals/a-g-e-interrupter/for/sensitive-skin