# SKIN1004 Hyalu-CICA Blue Serum for combination skin

**Lovi Fit: Superior fit for combination skin.**
Combination Skin Fit: High · Effectiveness: Superior · Safety: Excellent.

Page: https://lovi.care/skincare/ca/p/skin1004/hyalu-cica-blue-serum/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Brand: [SKIN1004](https://lovi.care/skincare/ca/brands/skin1004)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/ca/best/moisturizers)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best moisturizers for combination skin.

## Why this fit

- Excellent for your combination skin, this serum's niacinamide helps regulate oil production while sodium hyaluronate and panthenol provide superior hydration without exacerbating oiliness.
- The blend of hyaluronic acid derivatives and polyglutamic acid ensures deep moisturization, enhancing barrier resilience and addressing oily shine effectively.
- The formula is safe for your skin, containing soothing ingredients and no harsh components, making it ideal for daily use.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ca/p/skin1004/hyalu-cica-blue-serum/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/ca/p/skin1004/hyalu-cica-blue-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/ca/p/skin1004/hyalu-cica-blue-serum/for/combination-skin): Superior (this page)
- [Sensitive skin](https://lovi.care/skincare/ca/p/skin1004/hyalu-cica-blue-serum/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/ca/p/skin1004/hyalu-cica-blue-serum/for/acne-prone-skin): Superior
- [Skin with dark spots](https://lovi.care/skincare/ca/p/skin1004/hyalu-cica-blue-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/ca/p/skin1004/hyalu-cica-blue-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/ca/p/skin1004/hyalu-cica-blue-serum/for/dry-sensitive-skin): Superior
- [Oily acne-prone skin](https://lovi.care/skincare/ca/p/skin1004/hyalu-cica-blue-serum/for/oily-acne-prone-skin): Superior

## Key ingredients

Centella Asiatica Extract, Sodium Hyaluronate, Niacinamide, Panthenol, Ceramide Np

## What the research says

- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/))
- Poly-gamma-glutamic acid derived from a novel Bacillus subtilis strain dose-dependently increased skin barrier markers, hyaluronic acid synthesis, and aquaporin 3 expression in keratinocytes, and elevated filaggrin, involucrin, CD44, and aquaporin 3 expression in a reconstructed skin model compared to the control. ([International Journal of Molecular Sciences, 2025](https://pubmed.ncbi.nlm.nih.gov/39940752/))
- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans. ([Arzneimittel-Forschung, 2000](https://pubmed.ncbi.nlm.nih.gov/10965426/))
- Hyaluronic acid, hyaluronic acid plus dexpanthenol, and isotonic saline nasal sprays all significantly improved dry nose symptoms over four weeks in 240 patients, with hyaluronic acid plus dexpanthenol providing superior nasal moisturisation compared to the other two. ([Auris, Nasus, Larynx, 2020](https://pubmed.ncbi.nlm.nih.gov/32067777/))
- A combination serum containing galactomyces ferment filtrate, dexpanthenol, and Centella asiatica effectively treated post-acne hyperpigmentation in subjects with colored skin by significantly increasing lightness scores in Fitzpatrick skin type V and reducing the melanin index in Fitzpatrick skin type IV compared to placebo. ([Skinmed, 2021](https://pubmed.ncbi.nlm.nih.gov/33938432/))

## What reviewers say

Based on a very large amount of data, this serum is widely praised for its lightweight, gel-like texture that deeply hydrates and soothes without leaving a sticky residue, making it a favorite for oily, combination, and sensitive skin types, especially in humid climates. It effectively calms redness and layers well under makeup. However, users with very dry skin often find it insufficiently moisturizing on its own, and a small minority reported breakouts or irritation.

- Liked: Lightweight, non-sticky (mostly mentioned)
- Liked: Deeply hydrating (often mentioned)
- Liked: Good for oily/combo (often mentioned)
- Liked: Soothing, calming (often mentioned)
- Liked: Pleasant application (sometimes noted)
- Disliked: Not enough moisture (sometimes noted)
- Disliked: Caused breakouts (rarely noted)
- Disliked: Caused irritation (rarely noted)
- Disliked: Disliked scent (rarely noted)
- Disliked: Texture issues (rarely noted)

## How to apply

- Use this moisturizer in your AM and PM routine every day to control shine. Always pair with SPF in the morning.
- Apply this moisturizer after your cleanser and toner, right before your morning SPF.
- Gently press a small amount of the moisturizer into your skin and avoid harsh rubbing. Let it ⏳absorb for a minute.
- Apply the moisturizer on slightly damp skin to help it lock in moisture better. This keeps your combination skin balanced.
- Avoid the eye area when applying the moisturizer. Do a patch test before your first use.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes Skin1004 Hyalu-CICA Blue Serum one of the best fits for combination skin?

This serum is a great fit for your combination skin because its niacinamide helps control oil while sodium hyaluronate and panthenol deliver deep hydration without making oily areas worse. The formula also features polyglutamic acid to strengthen your skin barrier and keep moisture locked in safely every day.
Sources: [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Which ingredients make this serum a good fit for combination skin?

This serum is a great fit for your combination skin because niacinamide helps balance oil, while sodium hyaluronate and panthenol provide deep moisture without adding grease. Additional ingredients like polyglutamic acid and ceramide NP further support your skin barrier and keep shiny areas under control.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### What does Centella Asiatica Extract do for combination skin?

Centella Asiatica Extract helps balance combination skin by boosting moisture levels while keeping redness and irritation calm. It also supports skin barrier repair to help maintain smooth and healthy skin overall.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Hyaluronic Acid do for combination skin?

Hyaluronic acid is a great fit for combination skin because it quenches dry areas with a boost of hydration while keeping oily zones balanced. Regular use helps smooth out fine lines and makes your skin feel soft and plump without causing irritation.
Sources: [Dermatology and Therapy, 2021](https://pubmed.ncbi.nlm.nih.gov/34176098/), [Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/)

### Where does this serum go in a skincare routine for combination skin?

This treatment serum goes in the evening routine after cleansing and before moisturizing, which keeps the routine simple and safe around sun exposure. It is safe for daily use.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first to calm and hydrate your skin before putting on your retinol. Using a barrier-supporting moisturizer helps reduce the dryness and irritation that often come with retinol use.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### How often should I use this serum?

This serum is ideal for daily use, fitting nicely into your evening routine. Daily application helps keep your skin calm and hydrated without making it oily.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this serum clog pores, cause breakouts or purging for combination skin?

This serum is unlikely to clog pores or cause breakouts on your combination skin, as it has a low complaint rate for breakouts and features soothing ingredients with no harsh components. Niacinamide helps regulate oil production while lightweight hydrating ingredients provide moisture without feeling heavy or greasy.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Can I use this serum around the eyes or on my body?

You can safely use this serum around your eyes and on your body because its gentle, soothing formula is well tolerated by delicate skin. The moisturizing and calming ingredients help hydrate and soothe thinner skin areas without causing irritation.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for combination skin

- [Torriden DIVE-IN Low Molecular Hyaluronic Acid Serum](https://lovi.care/skincare/ca/p/torriden/dive-in-low-molecular-hyaluronic-acid-serum/for/combination-skin) — High fit — CA$21.81 at Amazon
- [MISSHA Super Aqua Ultra Hyalron Ampoule](https://lovi.care/skincare/ca/p/missha/super-aqua-ultra-hyalron-ampoule/for/combination-skin) — Average fit — CA$37.99 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/ca/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — CA$44.95 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/ca/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — CA$37.60 at Amazon
- SPF: [CeraVe AM Facial Moisturizing Lotion](https://lovi.care/skincare/ca/p/cerave/am-facial-moisturizing-lotion-spf-30/for/combination-skin) — Superior fit — CA$20.96 at Amazon

## Where to buy

- Amazon.ca: CA$24.78 (https://www.amazon.ca/dp/B0DBT6XH6B?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Water, Butylene Glycol, 1,2-Hexanediol, Niacinamide, Glycerin, Pantolactone, Hibiscus Esculentus Fruit Extract, Sodium Hyaluronate, Hydrolyzed Hyaluronic Acid, Methylpropanediol, Panthenol, Cetearyl Olivate, Carbomer, Arginine, Sorbitan Olivate, Caprylic Capric Triglyceride, Pyrus Communis Fruit Extract, Pentylene Glycol, Adenosine, Polyglutamic Acid, Rosa Damascena Flower Water, Artemisia Princeps Leaf Extract, Cucumis Melo Fruit Extract, Iris Florentina Root Extract, Ethylhexylglycerin, Hedera Helix Stem Extract Leaf, Sodium Phytate, Xanthan Gum, Maltodextrin, Hydrolyzed Gardenia Florida Extract, Hydrogenated Lecithin, Ceramide Np, Sodium Hyaluronate Crosspolymer, Hydrolyzed Sodium Hyaluronate
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/skin1004/hyalu-cica-blue-serum/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/skin1004/hyalu-cica-blue-serum/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/skin1004/hyalu-cica-blue-serum/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/skin1004/hyalu-cica-blue-serum/for/combination-skin
- France: https://lovi.care/skincare/fr/p/skin1004/hyalu-cica-blue-serum/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/skin1004/hyalu-cica-blue-serum/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/skin1004/hyalu-cica-blue-serum/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/skin1004/hyalu-cica-blue-serum/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/skin1004/hyalu-cica-blue-serum/for/combination-skin (this page)
- Australia: https://lovi.care/skincare/au/p/skin1004/hyalu-cica-blue-serum/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/skin1004/hyalu-cica-blue-serum/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/skin1004/hyalu-cica-blue-serum/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/skin1004/hyalu-cica-blue-serum/for/combination-skin