# SKIN&CO Truffle Therapy Serum for mature skin

**Lovi Fit: Average fit for mature skin.**
Normal Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/ca/p/skin-and-co/truffle-therapy-serum/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Brand: [SKIN&CO](https://lovi.care/skincare/ca/brands/skin-and-co)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/ca/best/moisturizers)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for mature skin; other moisturizers fit it better.

## Why this fit

- Offers moderate moisturizing for your normal skin due to glycerin and sodium hyaluronate, which provide hydration but do not directly address your goal of reducing wrinkles and fine lines.
- While ingredients like Rosa Canina Fruit Extract offer some antioxidant benefits, they are not potent enough to significantly target signs of aging.
- The product is safe for your normal skin, with no reported irritation risks from harsh or prohibited ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ca/p/skin-and-co/truffle-therapy-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/ca/p/skin-and-co/truffle-therapy-serum/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/ca/p/skin-and-co/truffle-therapy-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/ca/p/skin-and-co/truffle-therapy-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/ca/p/skin-and-co/truffle-therapy-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/ca/p/skin-and-co/truffle-therapy-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/ca/p/skin-and-co/truffle-therapy-serum/for/mature-skin): Average (this page)
- [Dry sensitive skin](https://lovi.care/skincare/ca/p/skin-and-co/truffle-therapy-serum/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/ca/p/skin-and-co/truffle-therapy-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Truffle Extract, Sodium Hyaluronate, Glycerin, Allantoin, Hydrolyzed Hibiscus Esculentus Extract

## What the research says

- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016](https://pubmed.ncbi.nlm.nih.gov/27475700/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment. ([Aesthetic Plastic Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29948103/))
- An alcohol-based hand rub containing 10% okra extract significantly increased skin hydration better than a control hand rub at 30 minutes and retained moisture for 210 minutes in volunteers. ([International Journal of Cosmetic Science, 2012](https://pubmed.ncbi.nlm.nih.gov/22404565/))
- Topical application of 30% okra fruit extract significantly increases fibroblast expression during the wound healing process after tooth extraction in Wistar rats compared to the control group. ([Infectious Disease Reports, 2020](https://pubmed.ncbi.nlm.nih.gov/32874458/))

## Why other moisturizers fit mature skin better

- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Treatment with a combination of niacinamide and hyaluronic acid improved skin aging signs and demonstrated a senomorphic effect by decreasing SASP and autocrine signaling genes in women. ([Scientific Reports, 2024](https://pubmed.ncbi.nlm.nih.gov/39009698/))

## What reviewers say

This serum is highly praised for improving skin texture, leaving it smoother, more hydrated, and radiant. It is frequently noted to absorb well and serve as a good base for makeup, with many users with sensitive and dry skin reporting no irritation. Some users find the price point to be high, and a few mention a unique scent or a slightly tacky finish.

- Liked: Improves texture (mostly mentioned)
- Liked: Hydrating and plumping (often mentioned)
- Liked: Makeup-friendly base (often mentioned)
- Liked: Gentle on skin (sometimes noted)
- Disliked: High price point (sometimes noted)
- Disliked: Tacky finish (rarely noted)
- Disliked: Unique scent (rarely noted)

## How to apply

- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help smooth fine lines.
- Apply this product after your toner and serum, but before your SPF in the morning. Follow your cleanser and toner steps to keep your skin balanced.
- Gently press a small amount into your face and neck. Avoid rubbing the skin too harshly to prevent extra tension.
- Apply the moisturizer on slightly damp skin to help lock in extra moisture. Clean skin helps the product absorb much more evenly.
- Avoid the sensitive eye area during application. Do a quick patch test before your very first use to stay safe.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does SKIN&CO Truffle Therapy Serum work for mature skin?

This serum works moderately well for mature skin by providing basic hydration through glycerin and sodium hyaluronate, though it is unlikely to directly target wrinkles and fine lines. A product for mature skin needs potent anti-wrinkle and skin-repairing ingredients that enhance vitality and smooth the skin.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this serum a good fit for mature skin?

Glycerin and sodium hyaluronate help keep your skin feeling hydrated and soft. To truly fit mature skin and reduce fine lines, a product of this type needs potent anti-aging ingredients and skin-repairing extracts.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Truffle Extract do for mature skin?

Truffle extract helps calm mature skin by reducing inflammation and supporting overall antioxidant defense. This ingredient works well to keep skin smooth and protected against everyday stress.
Sources: [Oxidative Medicine and Cellular Longevity, 2022](https://pubmed.ncbi.nlm.nih.gov/35251478/), [Archives of Microbiology, 2021](https://pubmed.ncbi.nlm.nih.gov/34940905/)

### What does Hyaluronic Acid do for mature skin?

Hyaluronic acid helps mature skin by deeply boosting moisture, improving elasticity, and smoothing the appearance of fine lines and wrinkles. Regular use keeps the skin looking plump and soft while supporting overall firmness and hydration.
Sources: [Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/), [Skin Research and Technology, 2024](https://pubmed.ncbi.nlm.nih.gov/38591218/)

### Where does this serum go in a skincare routine for mature skin?

Apply this serum in the evening step of your routine. Mature skin needs products with powerful antioxidants and potent anti-aging ingredients to effectively target wrinkles and fine lines.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol, applying it right before your retinol treatment to help keep your skin comfortable and hydrated. This product is safe for your skin with no reported irritation risks, but a product for mature skin needs potent antioxidants and ingredients that directly target wrinkles and fine lines.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### How often should I use this serum?

You can use this treatment in the evening as part of your routine, and some people may also use it in the morning. It is safe for your skin with no reported irritation risks.

### Can this serum clog pores, cause breakouts or purging for mature skin?

This serum is unlikely to clog pores or cause breakouts for mature skin, as it has a very safe formula with no harsh ingredients. However, because it only provides moderate moisture without strong anti-aging benefits, mature skin looking to reduce fine lines needs a treatment packed with potent antioxidants and firming peptides.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use this serum around the eyes or on my body?

You can safely use this moisturizing treatment around your eyes or on your body because it has a safe profile with no harsh or irritating ingredients. However, to truly target signs of aging on mature skin, a product of this type needs powerful anti-wrinkle ingredients like potent antioxidants and specialized peptides.

### Is this serum fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (parfum, coumarin, and linalool). Cetearyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for mature skin

- [MISSHA Super Aqua Ultra Hyalron Ampoule](https://lovi.care/skincare/ca/p/missha/super-aqua-ultra-hyalron-ampoule/for/mature-skin) — High fit — CA$37.99 at Amazon
- [Torriden DIVE-IN Low Molecular Hyaluronic Acid Serum](https://lovi.care/skincare/ca/p/torriden/dive-in-low-molecular-hyaluronic-acid-serum/for/mature-skin) — Average fit — CA$21.81 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/ca/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — CA$44.95 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/ca/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — CA$31.98 at Amazon
- SPF: [Torriden DIVE-IN Mild Sunscreen](https://lovi.care/skincare/ca/p/torriden/dive-in-mild-sunscreen/for/mature-skin) — Superior fit — CA$27.34 at Amazon

## Where to buy

No store in Canada has a checked price for this product, so the page shows none.

## Ingredients

Water, Coco-Caprylate, Glyceryl Stearate, Cetearyl Alcohol, Cyclopentasiloxane, Dimethicone, Glycerin, Chondrus Crispus Extract, Equisetum Arvense Extract, Potassium Palmitoyl Hydrolyzed Wheat Protein, Hydrolyzed Hibiscus Esculentus Extract, Tuber Melanosporum Extract, Rosa Canina Fruit Extract, Sodium Hyaluronate, Allantoin, Phenoxyethanol, Sodium Benzoate, Potassium Sorbate, Sucrose Palmitate, Propylene Glycol, Sodium Polyacrylate, P-Anisic Acid, Ethylhexylglycerin, Parfum, Citric Acid, Glucose, Disodium Edta, Coumarin, Linalool, Dextrin
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/skin-and-co/truffle-therapy-serum/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/skin-and-co/truffle-therapy-serum/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/skin-and-co/truffle-therapy-serum/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/skin-and-co/truffle-therapy-serum/for/mature-skin
- France: https://lovi.care/skincare/fr/p/skin-and-co/truffle-therapy-serum/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/skin-and-co/truffle-therapy-serum/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/skin-and-co/truffle-therapy-serum/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/skin-and-co/truffle-therapy-serum/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/skin-and-co/truffle-therapy-serum/for/mature-skin (this page)
- Australia: https://lovi.care/skincare/au/p/skin-and-co/truffle-therapy-serum/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/skin-and-co/truffle-therapy-serum/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/skin-and-co/truffle-therapy-serum/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/skin-and-co/truffle-therapy-serum/for/mature-skin
