# ROUND LAB 1025 Dokdo Ampoule for acne-prone skin

**Lovi Fit: Superior fit for acne-prone skin.**
Combination Skin Fit: Superior · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/ca/p/round-lab/1025-dokdo-ampoule/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Brand: [ROUND LAB](https://lovi.care/skincare/ca/brands/round-lab)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/ca/best/moisturizers)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best moisturizers for acne-prone skin.

## Why this fit

- Excellent suitability for your combination skin and acne, blemishes, and breakouts as sea water and hydrolyzed hyaluronic acid provide superior hydration and barrier support, while panthenol soothes inflammation.
- The inclusion of ceramides and tocopherol further enhances skin barrier function and offers antioxidant protection, complementing the primary hydrating and soothing benefits.
- This formula is exceptionally safe for your skin, containing no harsh ingredients and featuring beneficial components like panthenol and ceramide NP to prevent irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ca/p/round-lab/1025-dokdo-ampoule/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/ca/p/round-lab/1025-dokdo-ampoule/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/ca/p/round-lab/1025-dokdo-ampoule/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/ca/p/round-lab/1025-dokdo-ampoule/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/ca/p/round-lab/1025-dokdo-ampoule/for/acne-prone-skin): Superior (this page)
- [Skin with dark spots](https://lovi.care/skincare/ca/p/round-lab/1025-dokdo-ampoule/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/ca/p/round-lab/1025-dokdo-ampoule/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/ca/p/round-lab/1025-dokdo-ampoule/for/dry-sensitive-skin): Superior
- [Oily acne-prone skin](https://lovi.care/skincare/ca/p/round-lab/1025-dokdo-ampoule/for/oily-acne-prone-skin): High

## Key ingredients

Hydrolyzed Hyaluronic Acid, Hydrolyzed Collagen, Ceramide Np, Panthenol, Chondrus Crispus Extract

## What the research says

- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical application of TAC/Collagen postbiotics gel improved skin moisture score and inflammation index, and reduced porphyrins and brown spots in 20 volunteers with acne vulgaris. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35818134/))
- Topical collagen tripeptide application improved skin wrinkles, elasticity, and density while reducing advanced glycated end products in 22 Asian women over 4 weeks. ([International Journal of Molecular Sciences, 2022](https://pubmed.ncbi.nlm.nih.gov/35163025/))
- Marine collagen extracted from Greenland halibut skin showed a non-cytotoxic effect on fibroblast cells and provided a slight skin hydration effect when incorporated into cosmetic hydrogel formulations at dosages of 0.1, 0.25, and 0.5% in 23 healthy volunteers. ([Marine Drugs, 2023](https://pubmed.ncbi.nlm.nih.gov/36827098/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans. ([Arzneimittel-Forschung, 2000](https://pubmed.ncbi.nlm.nih.gov/10965426/))
- Hyaluronic acid, hyaluronic acid plus dexpanthenol, and isotonic saline nasal sprays all significantly improved dry nose symptoms over four weeks in 240 patients, with hyaluronic acid plus dexpanthenol providing superior nasal moisturisation compared to the other two. ([Auris, Nasus, Larynx, 2020](https://pubmed.ncbi.nlm.nih.gov/32067777/))
- Hybrid nanogels incorporating carrageenan, polyvinylpyrrolidone, and jojoba oil enhance and provide controlled cutaneous permeation of niacinamide, protecting human keratinocytes from UV radiation compared to standard delivery. ([Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/34834383/))
- Liposomes containing the carrageenan/echinochrome complex reduced lysosomal activity by 26%, decreased ROS levels by 23%, and improved migration by 47% in LPS-treated human HaCaT keratinocytes compared to untreated inflamed cells. ([Marine Drugs, 2024](https://pubmed.ncbi.nlm.nih.gov/39728136/))

## What reviewers say

Based on limited data, users with dehydrated and sensitive skin frequently praise this ampoule for its ability to provide deep hydration without heaviness, often describing it as "watery" and "plumping." It is widely celebrated for soothing irritation and layering well under makeup, though a minority of users find the finish slightly tacky or insufficient for extremely dry skin without a heavy moisturizer on top.

- Liked: Deeply hydrating (mostly mentioned)
- Liked: Lightweight texture (often mentioned)
- Liked: Soothing for sensitive skin (often mentioned)
- Liked: Layers well (sometimes noted)
- Disliked: Small size (sometimes noted)
- Disliked: Sticky finish (sometimes noted)
- Disliked: Caused breakouts (rarely noted)
- Disliked: Insufficient for dry skin (rarely noted)

## How to apply

- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help keep breakouts under control.
- Apply after your cleanser and toner, and make sure to use your SPF right after in the morning.
- Gently spread a small amount of moisturizer over your face using soft motions. Let it absorb into the skin for a minute before getting dressed or applying makeup.
- Apply on slightly damp skin to help lock in extra moisture. This keeps your combination skin balanced without feeling heavy.
- Avoid the eye area and do a patch test before your first use. Stop using if you feel any irritation.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes ROUND LAB 1025 Dokdo Ampoule one of the best fits for acne-prone skin?

This product is an excellent fit for acne-prone skin because sea water and hydrolyzed hyaluronic acid provide deep hydration and support the skin barrier, while panthenol helps soothe inflammation. Ceramides and tocopherol further strengthen the skin barrier and offer antioxidant protection to help prevent irritation.
Sources: [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Which ingredients make this ampoule a good fit for acne-prone skin?

This ampoule is a great fit for your acne-prone skin because sea water and hydrolyzed hyaluronic acid provide deep hydration while panthenol soothes inflammation. Ceramides and tocopherol further strengthen your skin barrier and protect against daily damage without causing irritation.
Sources: [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### What does Hydrolyzed Hyaluronic Acid do for acne-prone skin?

Hydrolyzed hyaluronic acid helps balance moisture in acne-prone skin while supporting a calm, clear complexion. Depending on its molecular weight and formulation, it may help manage skin oil production and inflammation safely.
Sources: [RSC Advances, 2026](https://pubmed.ncbi.nlm.nih.gov/41659329/)

### What does Hydrolyzed Collagen do for acne-prone skin?

Hydrolyzed Collagen is unlikely to treat acne directly, but it may help improve overall skin hydration and elasticity as part of your routine. This type of product needs added ingredients like niacinamide or soothing plant extracts to effectively calm breakouts and care for acne-prone skin.
Sources: [International Journal of Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33742704/)

### Where does it go in a skincare routine for acne-prone skin?

This treatment goes in the evening routine after cleansing and toning, followed by your moisturizer. Using it at night helps keep things simple and protects your skin while it soothes breakouts and delivers deep hydration without irritation.
Sources: [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Can I use this ampoule with retinol, and in what order?

Yes, you can use this ampoule with retinol to help calm redness and keep your skin comfortable. Apply the ampoule before your retinol product to help protect your skin barrier and lower the chances of dryness or irritation.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### How often should I use it?

Use this treatment in your evening routine. Daily application helps keep your skin calm and hydrated.
Sources: [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/), [Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/14571069/)

### Can it clog pores, cause breakouts or purging for acne-prone skin?

This product is a great fit for acne-prone skin because sea water and hyaluronic acid provide deep hydration while panthenol helps calm angry blemishes. Its formula is very gentle and safe, meaning it is unlikely to irritate your skin or cause breakouts.
Sources: [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Can I use this ampoule around the eyes or on my body?

You can use this ampoule around the eyes and on the body because it features a very safe formula with soothing panthenol and ceramides that help prevent irritation on delicate areas. The skin around the eyes is among the thinnest on the body, making gentle and hydrating ingredients like hyaluronic acid and panthenol particularly well-suited for these sensitive regions.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/), [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/)

### Is it fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for acne-prone skin

- [MISSHA Super Aqua Ultra Hyalron Ampoule](https://lovi.care/skincare/ca/p/missha/super-aqua-ultra-hyalron-ampoule/for/acne-prone-skin) — Average fit — CA$37.99 at Amazon

## Pairs well with

- Cleanser: [B.LAB Matcha Hydrating Foam Cleanser](https://lovi.care/skincare/ca/p/b-lab/matcha-hydrating-foam-cleanser/for/acne-prone-skin) — Superior fit — CA$22.95 at Amazon
- Hydrating Toner: [Paula's Choice Resist Advanced Replenishing Toner](https://lovi.care/skincare/ca/p/paula-s-choice/advanced-replenishing-toner/for/acne-prone-skin) — Superior fit — CA$41.00 at Amazon
- SPF: [innisfree Daily UV Defense Mineral Sunscreen](https://lovi.care/skincare/ca/p/innisfree/daily-uv-defense-mineral-sunscreen/for/acne-prone-skin) — Superior fit — CA$24.50 at Amazon

## Where to buy

- Amazon.ca: CA$28.36 (https://www.amazon.ca/dp/B08QRPCFL8?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
Prices checked 3 Nov 2026.

## Ingredients

Water, Butylene Glycol, Glycerin, Dipropylene Glycol, Propanediol, 1,2-Hexanediol, Sea Water, Hydrolyzed Hyaluronic Acid, Hydrolyzed Collagen, Panthenol, Chondrus Crispus Extract, Saccharum Officinarum Extract, Tromethamine, Ethylhexylglycerin, Caprylic Capric Triglyceride, Betaine, Dipotassium Glycyrrhizate, Glyceryl Glucoside, Hydrogenated Lecithin, Ceramide Np, Tocopherol, Carbomer, Xanthan Gum
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/round-lab/1025-dokdo-ampoule/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/round-lab/1025-dokdo-ampoule/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/round-lab/1025-dokdo-ampoule/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/round-lab/1025-dokdo-ampoule/for/acne-prone-skin
- France: https://lovi.care/skincare/fr/p/round-lab/1025-dokdo-ampoule/for/acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/round-lab/1025-dokdo-ampoule/for/acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/round-lab/1025-dokdo-ampoule/for/acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/round-lab/1025-dokdo-ampoule/for/acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/round-lab/1025-dokdo-ampoule/for/acne-prone-skin (this page)
- Australia: https://lovi.care/skincare/au/p/round-lab/1025-dokdo-ampoule/for/acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/round-lab/1025-dokdo-ampoule/for/acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/round-lab/1025-dokdo-ampoule/for/acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/round-lab/1025-dokdo-ampoule/for/acne-prone-skin