# REJURAN Rejuran® Healer Turnover Ampoule for oily acne-prone skin

**Lovi Fit: Average fit for oily acne-prone skin.**
Oily Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/ca/p/rejuran/healer-turnover-ampoule/for/oily-acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Brand: [REJURAN](https://lovi.care/skincare/ca/brands/rejuran)
Category: [Serums and treatments](https://lovi.care/skincare/ca/best/serums)

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for oily acne-prone skin; other serums fit it better.

## Why this fit

- Offers moderate suitability for your oily skin, as niacinamide and arbutin help regulate oil production and melanogenesis, though stronger oil control ingredients are absent.
- The formula provides general hydration and soothing benefits for your oily and acne-prone skin with glycerin and aloe barbadensis leaf juice, but these are secondary to your primary concerns.
- The product is safe for your oily skin, with no risks of irritation due to the absence of harsh ingredients and the inclusion of soothing agents like bisabolol and calendula officinalis flower extract.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ca/p/rejuran/healer-turnover-ampoule/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/ca/p/rejuran/healer-turnover-ampoule/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/ca/p/rejuran/healer-turnover-ampoule/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/ca/p/rejuran/healer-turnover-ampoule/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/ca/p/rejuran/healer-turnover-ampoule/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/ca/p/rejuran/healer-turnover-ampoule/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/ca/p/rejuran/healer-turnover-ampoule/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/ca/p/rejuran/healer-turnover-ampoule/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/ca/p/rejuran/healer-turnover-ampoule/for/oily-acne-prone-skin): Average (this page)

## Key ingredients

C-Pdrn

## What the research says

- Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer. ([The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical application of Low-Peony PDRN enhanced barrier recovery and improved periorbital skin elasticity in human subjects. ([International Journal of Molecular Sciences, 2025](https://pubmed.ncbi.nlm.nih.gov/41516097/))
- Polydeoxyribonucleotide promotes skin regeneration by increasing ERK phosphorylation, collagen accumulation, and cell proliferation and migration in fibroblasts while inhibiting ERK phosphorylation and inflammatory cytokine expression in keratinocytes. ([Molecular Medicine Reports, 2023](https://pubmed.ncbi.nlm.nih.gov/37350391/))
- A topical mixture of polydeoxyribonucleotide, vitamin C, and niacinamide delivered via a microneedling therapy system decreased skin pigmentation and increased skin elasticity by attenuating melanogenesis and the destruction of collagen and elastin fibers in a UV-B-radiated animal model. ([Molecules, 2022](https://pubmed.ncbi.nlm.nih.gov/35209068/))

## Why other serums fit oily acne-prone skin better

- Niacinamide and ferulic acid incorporated in a stable multiple emulsion successfully reduced melanin, sebum, and skin erythema while improving skin elasticity and hydration in human skin compared to a placebo. ([BioMed Research International, 2022](https://pubmed.ncbi.nlm.nih.gov/35342760/))

## What reviewers say

Users frequently report achieving a radiant "glass skin" appearance and deep hydration with this ampoule, noting significant improvements in skin texture and plumpness. It is often praised for its effectiveness in repairing damaged skin barriers, soothing redness, and aiding in the healing of acne scars. A small number of users with oily skin have found it to be slightly heavy for daytime application.

- Liked: Hydration and glow (mostly mentioned)
- Liked: Absorbs quickly (often mentioned)
- Liked: Smoother texture (often mentioned)
- Disliked: Expensive product (often mentioned)
- Liked: Calms redness (sometimes noted)
- Disliked: Awkward packaging (sometimes noted)
- Disliked: Minor breakouts (rarely noted)
- Disliked: Slightly sticky (rarely noted)

## How to apply

- Could be used as part of your PM routine. Start 3 times a week and build up to daily use if your skin tolerates it well.
- Apply your serum after cleansing and toning, but before putting on your moisturizer.
- Gently press 2 to 3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on clean, dry skin to help manage your blemishes safely.
- Do a patch test before your first use and avoid the delicate eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Rejuran Healer Turnover Ampoule work for oily acne-prone skin?

This treatment offers moderate suitability for your oily skin, as niacinamide and arbutin help regulate oil while soothing agents keep it safe from irritation. A product of this type needs strong oil control ingredients like vitamin C or propolis to better fit oily and acne-prone skin.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/)

### Which ingredients make this serum a good fit for oily acne-prone skin?

Niacinamide and arbutin help regulate oil and skin tone, while glycerin and aloe provide light hydration. Oily acne-prone skin typically needs stronger oil control ingredients and antioxidants like vitamin C or propolis to best address excess oil and blemishes.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/)

### What does C-Pdrn do for oily acne-prone skin?

C-Pdrn helps calm and smooth oily skin, though an average fit for acne-prone skin also needs ingredients that clear pores and control oil.

### Where does this serum go in a skincare routine for oily acne-prone skin?

Apply this treatment in the evening, as treatments with active ingredients fit best then for simplicity and extra safety around sun exposure. It is safe for your oily skin and unlikely to cause irritation, but to truly fit this skin well, a product of this type needs stronger oil control ingredients.

### Can I use this serum with retinol, and in what order?

You can use this treatment alongside retinol by applying it after your retinol product has fully absorbed into the skin. This product helps calm and hydrate, but oily acne-prone skin also needs stronger oil-controlling ingredients like salicylic acid or benzoyl peroxide for better breakout management.

### How often should I use this serum?

You can use this treatment in your evening routine, as treatments with actives go in the PM for simplicity and extra safety around sun exposure. If you want to use it more often, some treatments may also be used in the morning or twice a day.

### Can this serum clog pores, cause breakouts or purging for oily acne-prone skin?

This serum is unlikely to cause breakouts on oily skin, as it contains soothing ingredients and avoids harsh irritants. Oily acne-prone skin needs targeted oil-control ingredients and acne-fighting components to properly manage excess oil and prevent blemishes.

### Is this serum fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (benzyl alcohol).

## Alternatives for oily acne-prone skin

- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/ca/p/skin1004/probio-cica-intensive-ampoule/for/oily-acne-prone-skin) — High fit — CA$24.44 at Amazon
- [Dr.Althea Vitamin C Boosting Serum](https://lovi.care/skincare/ca/p/dr-althea/vitamin-c-boosting-serum/for/oily-acne-prone-skin) — High fit — CA$27.99 at Amazon
- [COSRX The Vitamin C 23 Serum](https://lovi.care/skincare/ca/p/cosrx/the-vitamin-c-23-serum/for/oily-acne-prone-skin) — High fit — CA$33.98 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/ca/p/cerave/foaming-facial-cleanser/for/oily-acne-prone-skin) — Superior fit — CA$20.96 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/ca/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-acne-prone-skin) — Superior fit — CA$37.60 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/ca/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/oily-acne-prone-skin) — Superior fit — CA$29.98 at Amazon

## Where to buy

- Amazon.ca: CA$76.50 (https://www.amazon.ca/dp/B08BZCY3Y1?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- Sephora: CA$72.00 (https://www.sephora.com/ca/en/product/rejuran-turnover-ampoule-P527746?skuId=3036001)
Prices checked 10 Oct – 3 Nov 2026.

## Ingredients

Blackberry Leaf Extract, Glycyrrhiza Glabra Callus Culture Extract Licorice Callus Culture Extract, Calendula Officinalis Flower Extract, Aloe Barbadensis Leaf Juice, Blueberry Fruit Extract, Morus Nigra Fruit Extract Morus Alba Fruit Extract, Arbutin, Butylene Glycol, Glycerin, Polysorbate 20, Hydrolyzed Dna, Hyaluronic Acid, Carbomer, Xanthan Gum, Adenosine, Tocopheryl Acetate, Niacinamide, Bisabolol, Peg-6, Phenoxyethanol, Caprylyl Glycol, Ethylhexylglycerin, Hexylene Glycol, Benzyl Alcohol, 12-Hexanediol, Dipropylene Glycol, Sodium Chloride, Trehalose, Urea
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/rejuran/healer-turnover-ampoule/for/oily-acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/rejuran/healer-turnover-ampoule/for/oily-acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/rejuran/healer-turnover-ampoule/for/oily-acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/rejuran/healer-turnover-ampoule/for/oily-acne-prone-skin
- France: https://lovi.care/skincare/fr/p/rejuran/healer-turnover-ampoule/for/oily-acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/rejuran/healer-turnover-ampoule/for/oily-acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/rejuran/healer-turnover-ampoule/for/oily-acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/rejuran/healer-turnover-ampoule/for/oily-acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/rejuran/healer-turnover-ampoule/for/oily-acne-prone-skin (this page)
- Australia: https://lovi.care/skincare/au/p/rejuran/healer-turnover-ampoule/for/oily-acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/rejuran/healer-turnover-ampoule/for/oily-acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/rejuran/healer-turnover-ampoule/for/oily-acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/rejuran/healer-turnover-ampoule/for/oily-acne-prone-skin