# REJURAN Rejuran® Healer Turnover Ampoule for dry skin

**Lovi Fit: High fit for dry skin.**
Dry Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/ca/p/rejuran/healer-turnover-ampoule/for/dry-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Brand: [REJURAN](https://lovi.care/skincare/ca/brands/rejuran)
Category: [Serums and treatments](https://lovi.care/skincare/ca/best/serums)

This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for dry skin; a few serums fit it even better.

## Why this fit

- This product offers excellent hydration for your dry skin, with hyaluronic acid and glycerin effectively drawing moisture in, complemented by blackberry leaf extract and calendula officinalis flower extract to soothe inflammation.
- Arbutin and niacinamide work synergistically to even out skin tone and brighten the complexion, addressing hyperpigmentation concerns.
- The formula is safe for your dry skin, containing no harsh ingredients and including soothing agents like aloe barbadensis leaf juice to minimize irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ca/p/rejuran/healer-turnover-ampoule/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/ca/p/rejuran/healer-turnover-ampoule/for/dry-skin): High (this page)
- [Combination skin](https://lovi.care/skincare/ca/p/rejuran/healer-turnover-ampoule/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/ca/p/rejuran/healer-turnover-ampoule/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/ca/p/rejuran/healer-turnover-ampoule/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/ca/p/rejuran/healer-turnover-ampoule/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/ca/p/rejuran/healer-turnover-ampoule/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/ca/p/rejuran/healer-turnover-ampoule/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/ca/p/rejuran/healer-turnover-ampoule/for/oily-acne-prone-skin): Average

## Key ingredients

C-Pdrn

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer. ([The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/))
- Topical application of Low-Peony PDRN enhanced barrier recovery and improved periorbital skin elasticity in human subjects. ([International Journal of Molecular Sciences, 2025](https://pubmed.ncbi.nlm.nih.gov/41516097/))
- Polydeoxyribonucleotide promotes skin regeneration by increasing ERK phosphorylation, collagen accumulation, and cell proliferation and migration in fibroblasts while inhibiting ERK phosphorylation and inflammatory cytokine expression in keratinocytes. ([Molecular Medicine Reports, 2023](https://pubmed.ncbi.nlm.nih.gov/37350391/))
- A topical mixture of polydeoxyribonucleotide, vitamin C, and niacinamide delivered via a microneedling therapy system decreased skin pigmentation and increased skin elasticity by attenuating melanogenesis and the destruction of collagen and elastin fibers in a UV-B-radiated animal model. ([Molecules, 2022](https://pubmed.ncbi.nlm.nih.gov/35209068/))

## What reviewers say

Users frequently report achieving a radiant "glass skin" appearance and deep hydration with this ampoule, noting significant improvements in skin texture and plumpness. It is often praised for its effectiveness in repairing damaged skin barriers, soothing redness, and aiding in the healing of acne scars. A small number of users with oily skin have found it to be slightly heavy for daytime application.

- Liked: Hydration and glow (mostly mentioned)
- Liked: Absorbs quickly (often mentioned)
- Liked: Smoother texture (often mentioned)
- Disliked: Expensive product (often mentioned)
- Liked: Calms redness (sometimes noted)
- Disliked: Awkward packaging (sometimes noted)
- Disliked: Minor breakouts (rarely noted)
- Disliked: Slightly sticky (rarely noted)

## How to apply

- Apply this serum PM, starting 3×/week and working up to daily use as your skin adjusts.
- Place the serum after cleansing and toner, but right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on slightly damp skin to help lock in extra moisture.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Rejuran Healer Turnover Ampoule a great fit for dry skin?

This product is a great fit because it offers excellent hydration for dry skin using hyaluronic acid and glycerin to draw moisture in, while soothing plant extracts calm inflammation. It is also safe and gentle, utilizing ingredients like aloe to minimize irritation while brightening the complexion.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this serum a good fit for dry skin?

This serum is a great fit for dry skin because it uses hyaluronic acid and glycerin to draw in plenty of moisture. It also contains soothing ingredients like aloe, blackberry leaf extract, and calendula to calm inflammation and keep irritation low.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does C-Pdrn do for dry skin?

C-PDRN helps improve hydration and supports the skin barrier for dry skin. This ingredient is unlikely to cause irritation and may provide soothing relief.
Sources: [Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41480692/), [International Journal of Molecular Sciences, 2025](https://pubmed.ncbi.nlm.nih.gov/41516097/)

### Where does this serum go in a skincare routine for dry skin?

This treatment goes in the evening routine after cleansing and before moisturizing, which keeps it simple and safe around sun exposure. This product is a great fit for your dry skin, providing excellent hydration with hyaluronic acid and glycerin while soothing irritation.

### Can I use this serum with retinol, and in what order?

You can use this treatment with retinol by applying this serum first and following with your retinol after it absorbs. This formula provides great hydration and soothing ingredients that may help keep dry skin comfortable while using a retinoid.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/)

### How often should I use this serum?

You can use this treatment in your evening routine. It is a great fit for your dry skin, providing wonderful hydration and soothing care with ingredients like hyaluronic acid and aloe leaf juice.
Sources: [Facial Plastic Surgery, 2014](https://pubmed.ncbi.nlm.nih.gov/24488631/)

### Can this serum clog pores, cause breakouts or purging for dry skin?

Minor breakouts are unlikely when using this serum on dry skin, as the formula is safe and free of harsh ingredients. It helps soothe skin without clogging pores, though mild irritation may occur in very rare cases.

### Is this serum fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (benzyl alcohol).

## Alternatives for dry skin

- [KraveBeauty Great Barrier Relief](https://lovi.care/skincare/ca/p/kravebeauty/great-barrier-relief/for/dry-skin) — Superior fit — CA$40.00 at Amazon
- [SKIN1004 Madagascar Centella Tone Brightening Capsule Ampoule](https://lovi.care/skincare/ca/p/skin1004/madagascar-centella-tone-brightening-capsule-ampoule/for/dry-skin) — Superior fit — CA$22.49 at Amazon
- [The Ordinary Matrixyl 10% + HA](https://lovi.care/skincare/ca/p/the-ordinary/matrixyl-10-ha/for/dry-skin) — Superior fit — CA$14.40 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/ca/p/cerave/hydrating-facial-cleanser/for/dry-skin) — Superior fit — CA$20.19 at Amazon
- Hydrating Toner: [Dear, Klairs Supple Preparation Unscented Toner](https://lovi.care/skincare/ca/p/dear-klairs/supple-preparation-unscented-toner/for/dry-skin) — Superior fit — CA$27.99 at Amazon
- Moisturizer: [Tata Harper Repairative Moisturizer](https://lovi.care/skincare/ca/p/tata-harper/repairative-moisturizer/for/dry-skin) — Superior fit — CA$162.00 at Amazon

## Where to buy

- Amazon.ca: CA$76.50 (https://www.amazon.ca/dp/B08BZCY3Y1?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- Sephora: CA$72.00 (https://www.sephora.com/ca/en/product/rejuran-turnover-ampoule-P527746?skuId=3036001)
Prices checked 10 Oct – 3 Nov 2026.

## Ingredients

Blackberry Leaf Extract, Glycyrrhiza Glabra Callus Culture Extract Licorice Callus Culture Extract, Calendula Officinalis Flower Extract, Aloe Barbadensis Leaf Juice, Blueberry Fruit Extract, Morus Nigra Fruit Extract Morus Alba Fruit Extract, Arbutin, Butylene Glycol, Glycerin, Polysorbate 20, Hydrolyzed Dna, Hyaluronic Acid, Carbomer, Xanthan Gum, Adenosine, Tocopheryl Acetate, Niacinamide, Bisabolol, Peg-6, Phenoxyethanol, Caprylyl Glycol, Ethylhexylglycerin, Hexylene Glycol, Benzyl Alcohol, 12-Hexanediol, Dipropylene Glycol, Sodium Chloride, Trehalose, Urea
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/rejuran/healer-turnover-ampoule/for/dry-skin
- United Kingdom: https://lovi.care/skincare/uk/p/rejuran/healer-turnover-ampoule/for/dry-skin
- Ireland: https://lovi.care/skincare/ie/p/rejuran/healer-turnover-ampoule/for/dry-skin
- Germany: https://lovi.care/skincare/de/p/rejuran/healer-turnover-ampoule/for/dry-skin
- France: https://lovi.care/skincare/fr/p/rejuran/healer-turnover-ampoule/for/dry-skin
- Italy: https://lovi.care/skincare/it/p/rejuran/healer-turnover-ampoule/for/dry-skin
- Netherlands: https://lovi.care/skincare/nl/p/rejuran/healer-turnover-ampoule/for/dry-skin
- Spain: https://lovi.care/skincare/es/p/rejuran/healer-turnover-ampoule/for/dry-skin
- Canada: https://lovi.care/skincare/ca/p/rejuran/healer-turnover-ampoule/for/dry-skin (this page)
- Australia: https://lovi.care/skincare/au/p/rejuran/healer-turnover-ampoule/for/dry-skin
- Singapore: https://lovi.care/skincare/sg/p/rejuran/healer-turnover-ampoule/for/dry-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/rejuran/healer-turnover-ampoule/for/dry-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/rejuran/healer-turnover-ampoule/for/dry-skin