# REJURAN Rejuran® Healer Turnover Ampoule for dry sensitive skin

**Lovi Fit: High fit for dry sensitive skin.**
Dry Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/ca/p/rejuran/healer-turnover-ampoule/for/dry-sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Brand: [REJURAN](https://lovi.care/skincare/ca/brands/rejuran)
Category: [Serums and treatments](https://lovi.care/skincare/ca/best/serums)

This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best serums for dry sensitive skin.

## Why this fit

- Offers high suitability for your dry skin, as glycerin, hyaluronic acid, and trehalose provide humectant action to draw water into the skin, addressing dryness and flakiness.
- The formulation also provides excellent skin brightening and evening of skin tone due to the presence of arbutin and niacinamide, which improve skin radiance.
- There are no risks of irritation for your dry and sensitive skin due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ca/p/rejuran/healer-turnover-ampoule/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/ca/p/rejuran/healer-turnover-ampoule/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/ca/p/rejuran/healer-turnover-ampoule/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/ca/p/rejuran/healer-turnover-ampoule/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/ca/p/rejuran/healer-turnover-ampoule/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/ca/p/rejuran/healer-turnover-ampoule/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/ca/p/rejuran/healer-turnover-ampoule/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/ca/p/rejuran/healer-turnover-ampoule/for/dry-sensitive-skin): High (this page)
- [Oily acne-prone skin](https://lovi.care/skincare/ca/p/rejuran/healer-turnover-ampoule/for/oily-acne-prone-skin): Average

## Key ingredients

C-Pdrn

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Sodium trehalose sulfate decreased transepidermal water loss and increased stratum corneum water content in participants with low stratum corneum water content when applied for 4 weeks compared to placebo. ([Skin Research and Technology, 2024](https://pubmed.ncbi.nlm.nih.gov/38606717/))
- Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer. ([The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/))
- Topical application of Low-Peony PDRN enhanced barrier recovery and improved periorbital skin elasticity in human subjects. ([International Journal of Molecular Sciences, 2025](https://pubmed.ncbi.nlm.nih.gov/41516097/))
- Polydeoxyribonucleotide promotes skin regeneration by increasing ERK phosphorylation, collagen accumulation, and cell proliferation and migration in fibroblasts while inhibiting ERK phosphorylation and inflammatory cytokine expression in keratinocytes. ([Molecular Medicine Reports, 2023](https://pubmed.ncbi.nlm.nih.gov/37350391/))
- A topical mixture of polydeoxyribonucleotide, vitamin C, and niacinamide delivered via a microneedling therapy system decreased skin pigmentation and increased skin elasticity by attenuating melanogenesis and the destruction of collagen and elastin fibers in a UV-B-radiated animal model. ([Molecules, 2022](https://pubmed.ncbi.nlm.nih.gov/35209068/))

## What reviewers say

Users frequently report achieving a radiant "glass skin" appearance and deep hydration with this ampoule, noting significant improvements in skin texture and plumpness. It is often praised for its effectiveness in repairing damaged skin barriers, soothing redness, and aiding in the healing of acne scars. A small number of users with oily skin have found it to be slightly heavy for daytime application.

- Liked: Hydration and glow (mostly mentioned)
- Liked: Absorbs quickly (often mentioned)
- Liked: Smoother texture (often mentioned)
- Disliked: Expensive product (often mentioned)
- Liked: Calms redness (sometimes noted)
- Disliked: Awkward packaging (sometimes noted)
- Disliked: Minor breakouts (rarely noted)
- Disliked: Slightly sticky (rarely noted)

## How to apply

- Use this PM routine for your evening skincare. Start using the serum 3 times a week and increase to daily use if your skin feels comfortable.
- Apply the serum after cleansing and toner, but right before your moisturizer. This step locks in deep hydration for dry skin.
- Gently press 2-3 drops of the serum into your skin using your palms. Let it absorb completely for a minute ⏱ before applying your next product.
- Since your skin is sensitive, apply the serum on completely dry skin for better tolerance and less irritation.
- Avoid the sensitive eye area during application. Always do a patch test before your first use to ensure your skin reacts well.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Rejuran Healer Turnover Ampoule a great fit for dry sensitive skin?

This treatment is a great fit because glycerin, hyaluronic acid, and trehalose draw water into the skin to relieve dryness and flakiness, while arbutin and niacinamide help brighten and even out your skin tone. It is also unlikely to irritate your skin since it lacks harsh ingredients.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/)

### Which ingredients make this serum a good fit for dry sensitive skin?

Glycerin, hyaluronic acid, and trehalose make this serum a great fit because they draw water into your skin to help stop dryness and flakiness. It is very unlikely to cause irritation on dry and sensitive skin since it does not contain harsh ingredients.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does C-Pdrn do for dry sensitive skin?

C-Pdrn helps calm and repair dry sensitive skin by supporting skin cell renewal and strengthening the moisture barrier. This ingredient helps soothe irritation and keeps the skin feeling soft and comfortable. Because dry sensitive skin needs extra moisture and protection against redness, products for this skin type typically need soothing ingredients and gentle hydrators like ceramides or hyaluronic acid.

### Where does this serum go in a skincare routine for dry sensitive skin?

This treatment goes in the evening routine after your toner and before your moisturizer. Using it at night keeps it simple and safe, and the product is unlikely to irritate your dry and sensitive skin.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying this treatment first and then following with your retinol. This product is unlikely to cause irritation for your dry and sensitive skin due to the absence of harsh ingredients, and its hydrating ingredients help draw water into the skin to prevent dryness.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/)

### How often should I use this serum?

This treatment is meant for your evening routine, used once a day. The absence of harsh ingredients helps ensure your sensitive skin is unlikely to experience irritation.

### Can this serum clog pores, cause breakouts or purging for dry sensitive skin?

This serum is a great fit for dry sensitive skin and is unlikely to cause irritation, clogged pores, or breakouts. Reviewers rarely report minor breakouts, and the formula avoids harsh ingredients that typically trigger reactions.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Is this serum fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (benzyl alcohol).

## Alternatives for dry sensitive skin

- [KraveBeauty Great Barrier Relief](https://lovi.care/skincare/ca/p/kravebeauty/great-barrier-relief/for/dry-sensitive-skin) — High fit — CA$40.00 at Amazon
- [The Ordinary Matrixyl 10% + HA](https://lovi.care/skincare/ca/p/the-ordinary/matrixyl-10-ha/for/dry-sensitive-skin) — High fit — CA$14.40 at Amazon
- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/ca/p/skin1004/probio-cica-intensive-ampoule/for/dry-sensitive-skin) — High fit — CA$24.44 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/ca/p/cerave/hydrating-facial-cleanser/for/dry-sensitive-skin) — Superior fit — CA$20.19 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/ca/p/clarins/soothing-toning-lotion/for/dry-sensitive-skin) — Superior fit — CA$49.00 at Amazon
- Moisturizer with Sun Protection: [d'Alba UVessence Mild Waterfull Sun Cream SPF 50](https://lovi.care/skincare/ca/p/d-alba/uvessence-mild-waterfull-sun-cream-spf-50/for/dry-sensitive-skin) — Superior fit — CA$38.00 at Amazon

## Where to buy

- Amazon.ca: CA$76.50 (https://www.amazon.ca/dp/B08BZCY3Y1?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- Sephora: CA$72.00 (https://www.sephora.com/ca/en/product/rejuran-turnover-ampoule-P527746?skuId=3036001)
Prices checked 10 Oct – 3 Nov 2026.

## Ingredients

Blackberry Leaf Extract, Glycyrrhiza Glabra Callus Culture Extract Licorice Callus Culture Extract, Calendula Officinalis Flower Extract, Aloe Barbadensis Leaf Juice, Blueberry Fruit Extract, Morus Nigra Fruit Extract Morus Alba Fruit Extract, Arbutin, Butylene Glycol, Glycerin, Polysorbate 20, Hydrolyzed Dna, Hyaluronic Acid, Carbomer, Xanthan Gum, Adenosine, Tocopheryl Acetate, Niacinamide, Bisabolol, Peg-6, Phenoxyethanol, Caprylyl Glycol, Ethylhexylglycerin, Hexylene Glycol, Benzyl Alcohol, 12-Hexanediol, Dipropylene Glycol, Sodium Chloride, Trehalose, Urea
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/rejuran/healer-turnover-ampoule/for/dry-sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/rejuran/healer-turnover-ampoule/for/dry-sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/rejuran/healer-turnover-ampoule/for/dry-sensitive-skin
- Germany: https://lovi.care/skincare/de/p/rejuran/healer-turnover-ampoule/for/dry-sensitive-skin
- France: https://lovi.care/skincare/fr/p/rejuran/healer-turnover-ampoule/for/dry-sensitive-skin
- Italy: https://lovi.care/skincare/it/p/rejuran/healer-turnover-ampoule/for/dry-sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/rejuran/healer-turnover-ampoule/for/dry-sensitive-skin
- Spain: https://lovi.care/skincare/es/p/rejuran/healer-turnover-ampoule/for/dry-sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/rejuran/healer-turnover-ampoule/for/dry-sensitive-skin (this page)
- Australia: https://lovi.care/skincare/au/p/rejuran/healer-turnover-ampoule/for/dry-sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/rejuran/healer-turnover-ampoule/for/dry-sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/rejuran/healer-turnover-ampoule/for/dry-sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/rejuran/healer-turnover-ampoule/for/dry-sensitive-skin