# Peter Thomas Roth Potent-C Niacinamide Discoloration Treatment for mature skin

**Lovi Fit: High fit for mature skin.**
Normal Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/ca/p/peter-thomas-roth/potent-c-niacinamide-discoloration-treatment/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Brand: [Peter Thomas Roth](https://lovi.care/skincare/ca/brands/peter-thomas-roth)
Category: [Serums and treatments](https://lovi.care/skincare/ca/best/serums)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for mature skin; a few serums fit it even better.

## Why this fit

- Highly suitable for your normal skin due to the presence of niacinamide and tranexamic acid, which regulate melanogenesis and provide anti-inflammatory action to address wrinkles and fine lines.
- The formulation also offers excellent brightening and evening of skin tone with niacinamide and alpha arbutin, promoting a more uniform complexion.
- The safety profile is excellent, with no risks of irritation for your normal skin due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ca/p/peter-thomas-roth/potent-c-niacinamide-discoloration-treatment/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/ca/p/peter-thomas-roth/potent-c-niacinamide-discoloration-treatment/for/dry-skin): Superior
- [Combination skin](https://lovi.care/skincare/ca/p/peter-thomas-roth/potent-c-niacinamide-discoloration-treatment/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/ca/p/peter-thomas-roth/potent-c-niacinamide-discoloration-treatment/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/ca/p/peter-thomas-roth/potent-c-niacinamide-discoloration-treatment/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/ca/p/peter-thomas-roth/potent-c-niacinamide-discoloration-treatment/for/dark-spots): Superior
- [Mature skin](https://lovi.care/skincare/ca/p/peter-thomas-roth/potent-c-niacinamide-discoloration-treatment/for/mature-skin): High (this page)
- [Dry sensitive skin](https://lovi.care/skincare/ca/p/peter-thomas-roth/potent-c-niacinamide-discoloration-treatment/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/ca/p/peter-thomas-roth/potent-c-niacinamide-discoloration-treatment/for/oily-acne-prone-skin): High

## Key ingredients

Niacinamide, Tetrahexyldecyl Ascorbate, Tranexamic Acid, Alpha Arbutin, Kojic Acid

## What the research says

- Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer. ([The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/))
- Encapsulation of alpha arbutin in an optimized ethosomal gel significantly improved skin melanin reduction, moisture content, and elasticity in human volunteers compared to conventional formulations. ([Heliyon, 2023](https://pubmed.ncbi.nlm.nih.gov/37681127/))
- Topical treatment of nicotinamide, alone or in combination with other active ingredients, reduces the progression of skin aging and hyperpigmentation in clinical trials while being well tolerated. ([Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- A non-hydroquinone topical formulation (SKNB19) improved hyperpigmentation by 28.5% in patient self-assessment and 27% in independent reviewer assessment compared with 4% hydroquinone in 18 adult subjects, while showing significantly less irritation and better tolerability. ([Journal of Cosmetic Science, 2020](https://pubmed.ncbi.nlm.nih.gov/33022197/))
- Combining a home-based radiofrequency device and arbutin cream reduced mMASI scores by 25.6% and melanin index by 22.8% at 8 weeks compared to baseline in 38 participants. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/39918262/))
- Polyvinyl pyrrolidone-K90/Eudragit RL100 dissolving microneedle patches loaded with alpha-arbutin and resveratrol enhanced intradermal delivery by approximately 2.6 times compared to cream and slightly decreased the melanin index in human participants without causing skin irritation. ([Biomaterials Science, 2023](https://pubmed.ncbi.nlm.nih.gov/37183632/))
- A topical formulation containing kojic acid, emblica extract, and glycolic acid demonstrated efficacy parity compared with hydroquinone 4% in multiethnic participants with mild to moderate facial dyschromia. ([Cutis, 2010](https://pubmed.ncbi.nlm.nih.gov/21049734/))
- A nanoemulsion containing 1 mg/mL kojic dipalmitate and 5% rosehip oil demonstrated high incorporation efficiency, suitable physicochemical stability, antioxidant and depigmenting efficacy close to 1 mM ascorbic acid, and no cytotoxicity at concentrations from 0.06% to 1% in vitro. ([Pharmaceutics, 2023](https://pubmed.ncbi.nlm.nih.gov/36839792/))
- Topical application of iron chelators kojic acid and deferiprone significantly accelerated wound healing in rats compared to control groups, with deferiprone showing superior efficacy due to higher antioxidant and iron chelation abilities. ([International Wound Journal, 2013](https://pubmed.ncbi.nlm.nih.gov/22621771/))

## What reviewers say

Users consistently praise this treatment for its ability to visibly fade post-acne marks and brighten the overall complexion, often noting its lightweight and non-sticky texture. While many see rapid results with general hyperpigmentation, some users report it is less effective on stubborn conditions like melasma and note the high price point.

- Liked: Fades dark spots (mostly mentioned)
- Liked: Brightens complexion (often mentioned)
- Liked: Elegant texture (sometimes noted)
- Liked: Gentle formulation (sometimes noted)
- Disliked: High price point (sometimes noted)
- Disliked: Ineffective on melasma (rarely noted)
- Disliked: Potential breakouts (rarely noted)
- Disliked: Slow results (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week, and work up to daily use if your skin likes it.
- Apply this serum after your toner and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- You can apply the serum on dry skin for the best results against fine lines.
- Always do a patch test before your first use and avoid the sensitive eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Peter Thomas Roth Potent-C Niacinamide Discoloration Treatment a great fit for mature skin?

Peter Thomas Roth Potent-C Niacinamide Discoloration Treatment is a great fit for mature skin because it features niacinamide, tranexamic acid, and alpha arbutin to help smooth lines and brighten dark spots. These ingredients work to make the complexion more even while keeping your skin calm and comfortable.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/)

### Which ingredients make this treatment a good fit for mature skin?

This treatment is a great fit for mature skin because it contains niacinamide and tranexamic acid, which help smooth wrinkles and fine lines while calming the skin. It also features alpha arbutin and kojic acid to brighten dark spots and give you a more even, smooth complexion with a very low risk of irritation.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/)

### What does Niacinamide do for mature skin?

Niacinamide helps mature skin by smoothing out fine lines and wrinkles, reducing dark spots, and improving overall skin elasticity. It is also very well tolerated and supports a strong skin barrier to keep skin looking healthy.
Sources: [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/), [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/)

### What does Vitamin C do for mature skin?

Vitamin C helps smooth out wrinkles, fade dark spots, and calm redness on mature skin. It also boosts collagen production to make skin firmer and protects against everyday environmental stress.
Sources: [The Journal of Clinical and Aesthetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/29104718/), [Dermatologic Surgery, 2002](https://pubmed.ncbi.nlm.nih.gov/11896774/)

### Where does this treatment go in a skincare routine for mature skin?

This treatment goes in the evening routine after cleansing and before moisturizing, keeping it simple and safe around sun exposure. Using targeted serums helps smooth fine lines and brighten mature skin for a more uniform complexion.

### Can I use this treatment with retinol, and in what order?

You can use this treatment with retinol by applying your retinol product first and following with this treatment, or by using one in the morning and the other at night. This approach helps you brighten your skin tone and address fine lines while keeping your routine gentle and safe.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/)

### How often should I use this treatment?

This treatment is a great fit for your mature skin and is safely used in your evening routine. Nonprescription topical treatments serve as a low-risk mainstay intervention for skin rejuvenation.
Sources: [Facial Plastic Surgery, 2014](https://pubmed.ncbi.nlm.nih.gov/24488631/), [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/)

### Can this treatment clog pores, cause breakouts or purging for mature skin?

This treatment is unlikely to cause breakouts or clogged pores for mature skin because its safety profile is excellent and it lacks harsh ingredients.

### Is this treatment fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for mature skin

- [Dr.Althea Vitamin C Boosting Serum](https://lovi.care/skincare/ca/p/dr-althea/vitamin-c-boosting-serum/for/mature-skin) — High fit — CA$27.99 at Amazon
- [The Ordinary Matrixyl 10% + HA](https://lovi.care/skincare/ca/p/the-ordinary/matrixyl-10-ha/for/mature-skin) — High fit — CA$14.40 at Amazon
- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/ca/p/skin1004/probio-cica-intensive-ampoule/for/mature-skin) — High fit — CA$24.44 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/ca/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — CA$44.95 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/ca/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — CA$31.98 at Amazon
- Moisturizer: [Obagi Hydrate Luxe Moisture-Rich Cream](https://lovi.care/skincare/ca/p/obagi/hydrate-luxe/for/mature-skin) — Superior fit — CA$103.73 at Amazon

## Where to buy

No store in Canada has a checked price for this product, so the page shows none.

## Ingredients

Water, Niacinamide, Dimethyl Isosorbide, Isononyl Isononanoate, Tranexamic Acid, Dimethicone, Caprylic Capric Triglyceride, Alpha Arbutin, Cetyl Alcohol, Glyceryl Stearate, Pentylene Glycol, Propanediol, C9-12 Alkane, Citric Acid, Glyceryl Stearate Se, Butyrospermum Parkii Butter Shea Butter, Tetrahexyldecyl Ascorbate, Kojic Acid, Resveratrol, Tocopheryl Acetate, Diethylhexyl Syringylidenemalonate, Hydrangea Arborescens Root Extract, Morus Alba Root Extract, Scutellaria Lateriflora Extract, Hydrolyzed Protein, Silica, Sodium Stearoyl Glutamate, Coco-Caprylate Caprate, Dimethiconol, Glycerin, Sodium Phytate, Potassium Sorbate, Sodium Benzoate, Caprylyl Glycol, Hexylene Glycol, Polysorbate 20, Ceteth-20, Steareth-20, Polyacrylate Crosspolymer-6, Peg-75 Stearate, Titanium Dioxide Ci 77891, Phenoxyethanol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/peter-thomas-roth/potent-c-niacinamide-discoloration-treatment/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/peter-thomas-roth/potent-c-niacinamide-discoloration-treatment/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/peter-thomas-roth/potent-c-niacinamide-discoloration-treatment/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/peter-thomas-roth/potent-c-niacinamide-discoloration-treatment/for/mature-skin
- France: https://lovi.care/skincare/fr/p/peter-thomas-roth/potent-c-niacinamide-discoloration-treatment/for/mature-skin
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- Spain: https://lovi.care/skincare/es/p/peter-thomas-roth/potent-c-niacinamide-discoloration-treatment/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/peter-thomas-roth/potent-c-niacinamide-discoloration-treatment/for/mature-skin (this page)
- Australia: https://lovi.care/skincare/au/p/peter-thomas-roth/potent-c-niacinamide-discoloration-treatment/for/mature-skin
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- United Arab Emirates: https://lovi.care/skincare/ae/p/peter-thomas-roth/potent-c-niacinamide-discoloration-treatment/for/mature-skin