# Paula's Choice 10% Niacinamide Booster for mature skin

**Lovi Fit: High fit for mature skin.**
Normal Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/ca/p/paula-s-choice/10-niacinamide-booster/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Brand: [Paula's Choice](https://lovi.care/skincare/ca/brands/paula-s-choice)
Category: [Serums and treatments](https://lovi.care/skincare/ca/best/serums)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for mature skin; a few serums fit it even better.

## Why this fit

- This product offers high suitability for your normal skin, with niacinamide and acetyl glucosamine effectively addressing your concerns about wrinkles and fine lines by promoting skin tone evening and pore minimization. Sodium hyaluronate and niacinamide further support your skin type by providing essential hydration and seboregulation.
- The inclusion of ascorbic acid and panthenol contributes to anti-aging benefits and overall skin health, enhancing the product's relevance for your primary goal.
- The safety profile is excellent, as the formula is free from harsh ingredients and contains soothing components like niacinamide and allantoin, ensuring no irritation for your normal skin.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ca/p/paula-s-choice/10-niacinamide-booster/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/ca/p/paula-s-choice/10-niacinamide-booster/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/ca/p/paula-s-choice/10-niacinamide-booster/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/ca/p/paula-s-choice/10-niacinamide-booster/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/ca/p/paula-s-choice/10-niacinamide-booster/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/ca/p/paula-s-choice/10-niacinamide-booster/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/ca/p/paula-s-choice/10-niacinamide-booster/for/mature-skin): High (this page)
- [Dry sensitive skin](https://lovi.care/skincare/ca/p/paula-s-choice/10-niacinamide-booster/for/dry-sensitive-skin): Superior
- [Oily acne-prone skin](https://lovi.care/skincare/ca/p/paula-s-choice/10-niacinamide-booster/for/oily-acne-prone-skin): High

## Key ingredients

Niacinamide, Acetyl Glucosamine, Sodium Hyaluronate, Glycyrrhiza Glabra Root Extract Licorice Root Extract, Panthenol Vitamin B5

## What the research says

- Topical 2% N-acetyl glucosamine reduced facial hyperpigmentation in an 8-week split-face clinical test, with an even greater effect observed when combined with 4% niacinamide. ([Journal of Cosmetic Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17348991/))
- Treatment with a combination of niacinamide and hyaluronic acid improved skin aging signs and demonstrated a senomorphic effect by decreasing SASP and autocrine signaling genes in women. ([Scientific Reports, 2024](https://pubmed.ncbi.nlm.nih.gov/39009698/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical 2% niacinamide significantly decreased sebum excretion rate in Japanese individuals and casual sebum levels in Caucasian individuals compared to placebo or baseline. ([Journal of Cosmetic and Laser Therapy, 2006](https://pubmed.ncbi.nlm.nih.gov/16766489/))
- N-acetyl-glucosamine-loaded nanostructured lipid carriers successfully delivered the hydrophilic agent through the skin and reduced melanin distribution in healthy volunteers. ([Advanced Pharmaceutical Bulletin, 2016](https://pubmed.ncbi.nlm.nih.gov/28101465/))
- Topical cosmetic products containing hyaluronic acid, N-acetyl glucosamine, and gamma-amino butyric acid improved skin hydration by 24.28% to 33.60%, elasticity by 11.98%, and skin lightening by 5.26% over 2 months in 20 female participants. ([Journal of Cosmetic and Laser Therapy, 2019](https://pubmed.ncbi.nlm.nih.gov/30040516/))
- Liposomes containing N-acetyl glucosamine prepared using the fusion method significantly increased skin moisture content compared to empty liposomes in human volunteers over a 5-hour period. ([Journal of Cosmetic Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23725302/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Combining 755 nm alexandrite laser with topical licorice gel significantly reduces terminal hair counts compared to alexandrite laser with placebo in women with idiopathic hirsutism. ([Evidence-based Complementary and Alternative Medicine, 2015](https://pubmed.ncbi.nlm.nih.gov/26273313/))
- Licochalcone A activated Nrf2 signaling, elevated cytoprotective enzymes, increased the reduced-to-oxidized glutathione ratio, and decreased reactive oxygen species in human fibroblasts and neutrophils, while a LicA-rich licorice extract lowered UVA-induced oxidative processes in vivo. ([Experimental Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25381913/))
- Bioactive glycyrrhizic acid and oxymatrine ionic liquid self-assembled nanomicelles significantly promoted the transdermal permeation, subcutaneous retention, and anti-photoaging efficacy of palmitoyl pentapeptide-4 in cellular and animal models compared to unformulated peptide. ([Advanced Science, 2025](https://pubmed.ncbi.nlm.nih.gov/39783908/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans. ([Arzneimittel-Forschung, 2000](https://pubmed.ncbi.nlm.nih.gov/10965426/))
- Hyaluronic acid, hyaluronic acid plus dexpanthenol, and isotonic saline nasal sprays all significantly improved dry nose symptoms over four weeks in 240 patients, with hyaluronic acid plus dexpanthenol providing superior nasal moisturisation compared to the other two. ([Auris, Nasus, Larynx, 2020](https://pubmed.ncbi.nlm.nih.gov/32067777/))

## What reviewers say

Users with oily and combination skin frequently praise this booster for its ability to visibly minimize pores and smooth rough texture, often describing the results as transformative for congestion and post-acne marks. A significant minority of reviewers experience adverse reactions, including breakouts and redness, while others find the price point high for the small quantity provided.

- Liked: Minimizes enlarged pores (mostly mentioned)
- Liked: Improves skin texture (often mentioned)
- Liked: Lightweight & layerable (often mentioned)
- Liked: Controls oil production (sometimes noted)
- Liked: Fades marks & redness (sometimes noted)
- Disliked: Causes breakouts/irritation (sometimes noted)
- Disliked: Expensive for size (sometimes noted)
- Disliked: No visible results (rarely noted)
- Disliked: Packaging issues (rarely noted)
- Disliked: Sticky/tacky finish (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week, and work up to daily use if your skin likes it.
- Apply this serum after your toner and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- You can apply the serum on dry skin for the best results against fine lines.
- Always do a patch test before your first use and avoid the sensitive eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Paula's Choice 10% Niacinamide Booster a great fit for mature skin?

Paula's Choice 10% Niacinamide Booster is a great fit for mature skin because it contains niacinamide and acetyl glucosamine, which help smooth out fine lines, even out skin tone, and minimize pores. It also provides essential hydration with sodium hyaluronate and features a safe, soothing formula that is unlikely to cause irritation.
Sources: [Journal of Cosmetic Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17348991/)

### Which ingredients make this treatment a good fit for mature skin?

This treatment is a great fit for mature skin because it contains niacinamide and acetyl glucosamine, which help smooth out fine lines and even out your skin tone. It also includes sodium hyaluronate to keep your skin hydrated, along with soothing components like panthenol and allantoin that are unlikely to cause irritation.
Sources: [Journal of Cosmetic Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17348991/)

### What does Niacinamide do for mature skin?

Niacinamide helps mature skin by smoothing out fine lines and wrinkles, reducing dark spots, and improving overall skin elasticity. It is also very well tolerated and supports a strong skin barrier to keep skin looking healthy.
Sources: [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/), [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/)

### What does Acetyl Glucosamine do for mature skin?

Acetyl Glucosamine helps keep mature skin looking smooth and bright while improving hydration and firmness. It may also help reduce dark spots and signs of aging on the face and neck.
Sources: [Journal of Cosmetic Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17348991/)

### Where does this treatment go in a skincare routine for mature skin?

This treatment goes in the evening routine after cleansing and before moisturizing, following Lovi's routine for mature skin. Putting treatments in the evening keeps things simple and adds extra safety around sun exposure.

### Can I use it with retinol, and in what order?

You can use this treatment alongside a retinol product, applying the treatment first and following with your retinol. Because this formula is very gentle and free from harsh ingredients, it is unlikely to cause irritation when layered.

### How often should I use this treatment?

You can use this treatment in the evening as part of your routine. It is unlikely to cause irritation and may help smooth fine lines and keep your skin calm.
Sources: [Journal of Cosmetic Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17348991/)

### Can it clog pores, cause breakouts or purging for mature skin?

This product is unlikely to cause breakouts or clog pores on mature skin, as it has an excellent safety profile with soothing ingredients like niacinamide and allantoin that prevent irritation. However, some reviewers do experience mild breakouts, so you may want to test it on a small area first.

### Is this treatment fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for mature skin

- [Dr.Althea Vitamin C Boosting Serum](https://lovi.care/skincare/ca/p/dr-althea/vitamin-c-boosting-serum/for/mature-skin) — High fit — CA$27.99 at Amazon
- [The Ordinary Matrixyl 10% + HA](https://lovi.care/skincare/ca/p/the-ordinary/matrixyl-10-ha/for/mature-skin) — High fit — CA$14.40 at Amazon
- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/ca/p/skin1004/probio-cica-intensive-ampoule/for/mature-skin) — High fit — CA$24.44 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/ca/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — CA$44.95 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/ca/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — CA$31.98 at Amazon
- Moisturizer: [Obagi Hydrate Luxe Moisture-Rich Cream](https://lovi.care/skincare/ca/p/obagi/hydrate-luxe/for/mature-skin) — Superior fit — CA$103.73 at Amazon

## Where to buy

No store in Canada has a checked price for this product, so the page shows none.

## Ingredients

Water, Niacinamide, Acetyl Glucosamine, Ascorbyl Glucoside Ascorbic Acid, Butylene Glycol, Sodium Hyaluronate, Allantoin, Boerhavia Diffusa Root Extract, Glycerin, Dipotassium Glycyrrhizate, Glycyrrhiza Glabra Root Extract Licorice Root Extract, Ubiquinone, Epigallocatechin Gallate, Beta-Glucan, Panthenol, Carnosine, Genistein, Citric Acid, Sodium Citrate, Sodium Hydroxide, Xanthan Gum, Disodium Edta, Ethylhexylglycerin, Phenoxyethanol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/paula-s-choice/10-niacinamide-booster/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/paula-s-choice/10-niacinamide-booster/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/paula-s-choice/10-niacinamide-booster/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/paula-s-choice/10-niacinamide-booster/for/mature-skin
- France: https://lovi.care/skincare/fr/p/paula-s-choice/10-niacinamide-booster/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/paula-s-choice/10-niacinamide-booster/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/paula-s-choice/10-niacinamide-booster/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/paula-s-choice/10-niacinamide-booster/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/paula-s-choice/10-niacinamide-booster/for/mature-skin (this page)
- Australia: https://lovi.care/skincare/au/p/paula-s-choice/10-niacinamide-booster/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/paula-s-choice/10-niacinamide-booster/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/paula-s-choice/10-niacinamide-booster/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/paula-s-choice/10-niacinamide-booster/for/mature-skin