# Origins Plantscription Multi-Powered Youth Serum for dry sensitive skin

**Lovi Fit: Average fit for dry sensitive skin.**
Dry Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/ca/p/origins/plantscription-multi-powered-youth-serum/for/dry-sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Brand: [Origins](https://lovi.care/skincare/ca/brands/origins)
Category: [Serums and treatments](https://lovi.care/skincare/ca/best/serums)

This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for dry sensitive skin; other serums fit it better.

## Why this fit

- Offers moderate suitability for your dry skin due to the presence of glycerin and sodium hyaluronate for humectant action, but lacks sufficient emollient ingredients for optimal hydration.
- The product provides general skincare benefits, such as hydration and soothing, which are supportive for your dry or flaky skin, but it does not contain specialized ingredients targeting dryness and flakiness.
- There are no risks of irritation for your dry and sensitive skin due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ca/p/origins/plantscription-multi-powered-youth-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/ca/p/origins/plantscription-multi-powered-youth-serum/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/ca/p/origins/plantscription-multi-powered-youth-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/ca/p/origins/plantscription-multi-powered-youth-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/ca/p/origins/plantscription-multi-powered-youth-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/ca/p/origins/plantscription-multi-powered-youth-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/ca/p/origins/plantscription-multi-powered-youth-serum/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/ca/p/origins/plantscription-multi-powered-youth-serum/for/dry-sensitive-skin): Average (this page)
- [Oily acne-prone skin](https://lovi.care/skincare/ca/p/origins/plantscription-multi-powered-youth-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Niacinamide, Sodium Hyaluronate, Acetyl Hexapeptide-8, Anogeissus Leiocarpus Bark Extract, Hibiscus Abelmoschus Extract

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Treatment with cross-linked hyaluronic acid-based microneedle patches combined with acetyl hexapeptide-8 or epidermal growth factor significantly improved wrinkles and skin hydration compared to the patch alone in Korean females over 29 days. ([Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Argireline treatment twice daily for 4 weeks produced a significant anti-wrinkle effect with 48.9% total efficacy and decreased skin roughness in Chinese subjects compared with 0% efficacy and no decrease in roughness in the placebo group. ([American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/))
- Acetyl hexapeptide-3 and tripeptide-10 citrulline demonstrated antiwrinkle efficacy and decreased transepidermal water loss in twenty-four healthy volunteers compared to control groups, though synergistic effects between the two peptides remained unclear. ([Journal of Cosmetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28150423/))
- Daily topical acetyl hexapeptide-8 showed a trend toward a longer time until return to baseline Jankovic Blepharospasm Rating Scale scores compared to placebo (3.7 months vs. 3.0 months) in 24 patients with blepharospasm receiving botulinum toxin therapy. ([European Journal of Neurology, 2013](https://pubmed.ncbi.nlm.nih.gov/23146065/))
- A Hibiscus Abelmoschus seed extract mimicked heparan sulphate-like properties to protect FGF-2 from thermal degradation and stimulated sulphated GAG synthesis in skin fibroblasts. ([International Journal of Cosmetic Science, 2009](https://pubmed.ncbi.nlm.nih.gov/19849726/))

## Why other serums fit dry sensitive skin better

- Tocopherol succinate-loaded ethosomal gel increased skin deposition, stability, moisture, and mechanical properties in 13 human subjects compared to a control gel over 12 weeks. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35274433/))
- In 50 participants with sensitive skin, a Ceramide NP C15-containing emollient improved skin barrier function with a significant reduction in transepidermal water loss and induced modest changes in skin microbiota compared to the vehicle. ([Skin Pharmacology and Physiology, 2026](https://pubmed.ncbi.nlm.nih.gov/41758783/))
- Hydrogels containing vitamin E-loaded nanostructured lipid carriers exhibited better occlusive properties and long-lasting effects, while vitamin E-loaded nanoemulsions performed a faster skin hydration effect and were selected as more attractive for skin application. ([Colloids and Surfaces. B, Biointerfaces, 2019](https://pubmed.ncbi.nlm.nih.gov/30974262/))

## What reviewers say

Based on a very large amount of data, users frequently praise this serum for its lightweight, fast-absorbing texture that effectively hydrates and plumps the skin, often noting an immediate 'youthful bounce' and smoother texture. While many long-time users appreciate its ability to reduce redness and fine lines, a significant portion of recent reviews express disappointment over a formula change, citing a watery consistency and inferior packaging compared to the original version.

- Liked: Lightweight absorption (mostly mentioned)
- Liked: Hydrating and plumping (often mentioned)
- Liked: Improves skin texture (often mentioned)
- Disliked: Inferior new formula (often mentioned)
- Liked: Firming effects (sometimes noted)
- Liked: Soothing and calming (sometimes noted)
- Disliked: High price point (sometimes noted)
- Disliked: Poor packaging quality (sometimes noted)
- Disliked: Lack of visible results (rarely noted)
- Disliked: Sticky residue (rarely noted)

## How to apply

- Use this PM routine for your evening skincare. Start using the serum 3 times a week and increase to daily use if your skin feels comfortable.
- Apply the serum after cleansing and toner, but right before your moisturizer. This step locks in deep hydration for dry skin.
- Gently press 2-3 drops of the serum into your skin using your palms. Let it absorb completely for a minute ⏱ before applying your next product.
- Since your skin is sensitive, apply the serum on completely dry skin for better tolerance and less irritation.
- Avoid the sensitive eye area during application. Always do a patch test before your first use to ensure your skin reacts well.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Origins Plantscription Multi-Powered Youth Serum work for dry sensitive skin?

This serum works moderately well for dry sensitive skin because it includes ingredients that draw in moisture, though it lacks enough rich softeners for deep hydration. It is unlikely to cause irritation, but a product of this type needs extra soothing and nourishing ingredients, along with skin barrier supporters like ceramides, to properly comfort dry skin.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/)

### Which ingredients make this serum a good fit for dry sensitive skin?

This serum works for your dry sensitive skin because it contains glycerin and sodium hyaluronate, which help draw moisture into the skin. However, since this is an average fit, a product of this type needs rich softening and nourishing ingredients like ceramides and heavier oils to lock in hydration and deeply comfort dry skin.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Niacinamide do for dry sensitive skin?

Niacinamide helps dry sensitive skin by calming irritation and keeping moisture locked in so your face feels soft and smooth. It works to build up your skin barrier and calm redness while being very gentle and unlikely to cause irritation.
Sources: [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/), [International Journal of Pharmaceutics, 2013](https://pubmed.ncbi.nlm.nih.gov/23220080/)

### What does Hyaluronic Acid do for dry sensitive skin?

Hyaluronic acid is a great fit for dry, sensitive skin because it brings a large boost in hydration, making the skin feel soft and smooth while improving barrier function. It helps calm tightness and dryness, and is unlikely to cause irritation.
Sources: [Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/), [Dermatology and Therapy, 2021](https://pubmed.ncbi.nlm.nih.gov/34176098/)

### Where does it go in a skincare routine for dry sensitive skin?

You can use this treatment in your evening routine after cleansing and toning, followed by a moisturizer. A product of this type for dry sensitive skin needs rich softening and smoothing ingredients to lock in hydration and deeply comfort dry areas.

### Can I use this serum with retinol, and in what order?

You can use this treatment with retinol by applying the treatment after your toner and before your moisturizer in your evening routine. This product is unlikely to irritate your dry and sensitive skin because it lacks harsh ingredients, but it needs more nourishing oils and butters to provide optimal comfort for dry skin.

### How often should I use it?

This treatment is applied in the evening, starting once a week to see how your skin reacts. For dry and sensitive skin, a product of this type needs rich smoothing creams and oils to lock in moisture and deeply soften dry patches.

### Can this serum clog pores, cause breakouts or purging for dry sensitive skin?

This serum is unlikely to cause clogged pores, breakouts or purging for your dry sensitive skin because it does not contain harsh ingredients that typically trigger irritation or congestion.

### Is it fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (linalool, geraniol, citronellol, and limonene).

## Alternatives for dry sensitive skin

- [KraveBeauty Great Barrier Relief](https://lovi.care/skincare/ca/p/kravebeauty/great-barrier-relief/for/dry-sensitive-skin) — High fit — CA$40.00 at Amazon
- [The Ordinary Matrixyl 10% + HA](https://lovi.care/skincare/ca/p/the-ordinary/matrixyl-10-ha/for/dry-sensitive-skin) — High fit — CA$14.40 at Amazon
- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/ca/p/skin1004/probio-cica-intensive-ampoule/for/dry-sensitive-skin) — High fit — CA$24.44 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/ca/p/cerave/hydrating-facial-cleanser/for/dry-sensitive-skin) — Superior fit — CA$20.19 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/ca/p/clarins/soothing-toning-lotion/for/dry-sensitive-skin) — Superior fit — CA$49.00 at Amazon
- Moisturizer with Sun Protection: [d'Alba UVessence Mild Waterfull Sun Cream SPF 50](https://lovi.care/skincare/ca/p/d-alba/uvessence-mild-waterfull-sun-cream-spf-50/for/dry-sensitive-skin) — Superior fit — CA$38.00 at Amazon

## Where to buy

- Amazon.ca: CA$118.00 (https://www.amazon.ca/dp/B0927BFCRK?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- Shoppers Drug Mart: CA$86.00 (https://www.shoppersdrugmart.ca/origins-plantscription-multi-powered-youth-serum/p/BB_717334250475?variantCode=717334250444)
Prices checked 24 Oct – 2 Nov 2026.

## Ingredients

Water, Butylene Glycol, Niacinamide, Glycerin, Heptyl Undecylenate, Octyldodecanol, Glycereth-26, Sodium Acrylates Copolymer, Algae Extract, Illicium Verum Seed Oil Fruit Anise Seed Oil Fruit, Bergamot Oil Fruit, Pelargonium Graveolens Oil Flower, Lavandula Angustifolia Oil Lavender Oil, Lemon Peel Oil, Litsea Cubeba Oil Fruit, Citrus Nobilis Peel Oil Mandarin Orange Peel Oil, Nutmeg Kernel Oil, Citrus Aurantium Dulcis Oil, Rosa Damascena Oil Flower, Hibiscus Abelmoschus Extract, Carthamus Tinctorius Seed Oil, Linalool, Geraniol, Citronellol, Limonene, Anogeissus Leiocarpus Bark Extract, Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1, Acetyl Octapeptide-3, Palmitoyl Tetrapeptide-7, Palmitoyl Hexapeptide-12, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Sodium Hyaluronate, Sigesbeckia Orientalis Extract, Commiphora Mukul Extract Resin, Laminaria Digitata Extract, Glucosamine Hcl, Bambusa Vulgaris Extract, Caffeine, Rosmarinus Officinalis Leaf Extract Rosemary Leaf Extract, Molasses Saccharum Officinarum Extrait De Mélasse Extract, Tocopheryl Acetate, Scutellaria Baicalensis Root Extract, Pyrus Malus Fruit Extract, Cucumis Sativus Fruit Extract, Pisum Sativum Extract, Caprylic Capric Triglyceride, Lecithin, Xanthan Gum, Caprylyl Glycol, Hexylene Glycol, Peg-8, Glyceryl Polymethacrylate, Carbomer, Polysorbate 20, Sodium Metabisulfite, Sodium Sulfite, Disodium Edta, Sodium Phytate, Bht, Potassium Sorbate, Phenoxyethanol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/origins/plantscription-multi-powered-youth-serum/for/dry-sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/origins/plantscription-multi-powered-youth-serum/for/dry-sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/origins/plantscription-multi-powered-youth-serum/for/dry-sensitive-skin
- Germany: https://lovi.care/skincare/de/p/origins/plantscription-multi-powered-youth-serum/for/dry-sensitive-skin
- France: https://lovi.care/skincare/fr/p/origins/plantscription-multi-powered-youth-serum/for/dry-sensitive-skin
- Italy: https://lovi.care/skincare/it/p/origins/plantscription-multi-powered-youth-serum/for/dry-sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/origins/plantscription-multi-powered-youth-serum/for/dry-sensitive-skin
- Spain: https://lovi.care/skincare/es/p/origins/plantscription-multi-powered-youth-serum/for/dry-sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/origins/plantscription-multi-powered-youth-serum/for/dry-sensitive-skin (this page)
- Australia: https://lovi.care/skincare/au/p/origins/plantscription-multi-powered-youth-serum/for/dry-sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/origins/plantscription-multi-powered-youth-serum/for/dry-sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/origins/plantscription-multi-powered-youth-serum/for/dry-sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/origins/plantscription-multi-powered-youth-serum/for/dry-sensitive-skin