# Olay Retinol 24 Night Serum for mature skin

**Lovi Fit: High fit for mature skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/ca/p/olay/retinol-24-night-serum/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Brand: [Olay](https://lovi.care/skincare/ca/brands/olay)
Category: [Serums and treatments](https://lovi.care/skincare/ca/best/serums)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for mature skin; a few serums fit it even better.

## Why this fit

- Highly suitable for your normal skin, this serum utilizes retinol and retinyl propionate to effectively minimize fine lines and wrinkles by stimulating collagen production.
- Niacinamide further supports skin health by regulating melanogenesis, while ingredients like Dimethicone and Glycerin provide essential hydration.
- The formulation is safe for your skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ca/p/olay/retinol-24-night-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/ca/p/olay/retinol-24-night-serum/for/dry-skin): Low
- [Combination skin](https://lovi.care/skincare/ca/p/olay/retinol-24-night-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/ca/p/olay/retinol-24-night-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/ca/p/olay/retinol-24-night-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/ca/p/olay/retinol-24-night-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/ca/p/olay/retinol-24-night-serum/for/mature-skin): High (this page)
- [Dry sensitive skin](https://lovi.care/skincare/ca/p/olay/retinol-24-night-serum/for/dry-sensitive-skin): Low
- [Oily acne-prone skin](https://lovi.care/skincare/ca/p/olay/retinol-24-night-serum/for/oily-acne-prone-skin): High

## Key ingredients

Retinol, Niacinamide, Palmitoyl Pentapeptide-4, Glycerin, Dimethicone

## What the research says

- Topical 0.4% retinol significantly increased epidermal thickness, dermal vascularity, and extracellular matrix production by stimulating keratinocyte proliferation, endothelial cell proliferation, and fibroblast activation in naturally aged human skin compared to vehicle. ([International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/))
- Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer. ([The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging. ([The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/))
- Silicone particles encapsulating retinol increased its half-life by 9-fold and yielded 12-23% lower skin irritation in human subjects compared to Microsponge particles while maintaining biological activity. ([Journal of Controlled Release, 2018](https://pubmed.ncbi.nlm.nih.gov/29604311/))
- Topical stabilized retinol treatment induced HAS gene expression and increased hyaluronic acid production in human skin in vitro, ex vivo, and in vivo compared to vehicle. ([Archives of Dermatological Research, 2017](https://pubmed.ncbi.nlm.nih.gov/28247017/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical 2% niacinamide significantly decreased sebum excretion rate in Japanese individuals and casual sebum levels in Caucasian individuals compared to placebo or baseline. ([Journal of Cosmetic and Laser Therapy, 2006](https://pubmed.ncbi.nlm.nih.gov/16766489/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Wearing an N95 mask alone compared to using dimethicone cream or hydrocolloid dressing caused more adverse skin reactions among 73 military health care workers, with no significant differences in fit test failure rates between groups. ([Military Medicine, 2024](https://pubmed.ncbi.nlm.nih.gov/38771104/))
- A dimethicone skin protectant lotion significantly decreased visual scoring and transepidermal water loss compared to vehicle control and SLS-only treated sites in 12 healthy humans exposed to sodium lauryl sulfate. ([Skin Research and Technology, 2000](https://pubmed.ncbi.nlm.nih.gov/11428946/))
- Treatment with a moisturizer containing dimethicone and glycerine increased epidermal thickness by 0.019 mm, improved barrier function by decreasing transepidermal water loss by 13%, decreased melanin intensity, and induced keratins 6 and 16 in fifteen women with moderately photoaged forearms. ([Clinical and Experimental Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17137484/))

## What reviewers say

Users consistently praise this serum for its gentle, non-drying formula that leaves skin feeling silky and hydrated, making it an excellent choice for retinol beginners. While many report noticeably smoother texture and a brighter complexion, some users note that deep wrinkle reduction takes significant time and the product can pill if layered incorrectly.

- Liked: Gentle & non-irritating (mostly mentioned)
- Liked: Smoother skin texture (mostly mentioned)
- Liked: Hydrating formula (often mentioned)
- Liked: Lightweight absorption (often mentioned)
- Liked: Brightening effect (sometimes noted)
- Disliked: Product pilling (sometimes noted)
- Disliked: Slow results (sometimes noted)
- Disliked: Packaging issues (rarely noted)
- Disliked: Price point (rarely noted)
- Disliked: Sticky residue (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week, and work up to daily use if your skin likes it.
- Apply this serum after your toner and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- You can apply the serum on dry skin for the best results against fine lines.
- Always do a patch test before your first use and avoid the sensitive eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Olay Retinol 24 a great fit for mature skin?

Olay Retinol 24 Night Serum is a great fit for mature skin because it uses retinol and retinyl propionate to smooth out fine lines and wrinkles. It also includes niacinamide, dimethicone, and glycerin to support overall skin health and provide essential hydration without harsh irritation.
Sources: [International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/)

### Which ingredients make this serum a good fit for mature skin?

Retinol and retinyl propionate make this serum a great fit by stimulating collagen production to help minimize fine lines and wrinkles. Niacinamide further supports skin health by regulating skin pigment, while glycerin and dimethicone provide essential hydration.

### What does Retinol do for mature skin?

Retinol helps smooth out fine lines and wrinkles while improving overall skin thickness and firmness over time. It may also cause temporary dryness, scaling, or stinging as your skin gets used to it.
Sources: [The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/)

### What does Niacinamide do for mature skin?

Niacinamide helps mature skin by smoothing out fine lines and wrinkles, reducing dark spots, and improving overall skin elasticity. It is also very well tolerated and supports a strong skin barrier to keep skin looking healthy.
Sources: [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/), [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/)

### Where does this serum go in a skincare routine for mature skin?

This serum goes in the evening routine after cleansing and toning, followed by a moisturizer. Applying it at night provides extra safety around sun exposure while helping minimize fine lines and wrinkles.

### Can I use this serum with vitamin C, and in what order?

You can use this serum with vitamin C by applying vitamin C in the morning and this retinol serum at night to avoid overwhelming your skin. Using them at different times of day helps minimize potential irritation while still giving you the smoothing and brightening benefits of both ingredients.

### How often should I use this serum?

Use this serum in your evening routine, applying it after cleansing and before moisturizing. It helps smooth fine lines and keeps mature skin hydrated with a low risk of irritation.
Sources: [Facial Plastic Surgery, 2014](https://pubmed.ncbi.nlm.nih.gov/24488631/)

### Can this serum clog pores, cause breakouts or purging for mature skin?

This serum is unlikely to clog pores or cause breakouts on mature skin, though active ingredients like retinol may cause a mild temporary purging phase as they speed up skin renewal. Its lightweight formulation relies on hydrating ingredients that help keep skin soft and smooth without feeling heavy.
Sources: [International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/)

### Is this serum fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (benzyl alcohol).

## Alternatives for mature skin

- [Dr.Althea Vitamin C Boosting Serum](https://lovi.care/skincare/ca/p/dr-althea/vitamin-c-boosting-serum/for/mature-skin) — High fit — CA$27.99 at Amazon
- [The Ordinary Matrixyl 10% + HA](https://lovi.care/skincare/ca/p/the-ordinary/matrixyl-10-ha/for/mature-skin) — High fit — CA$14.40 at Amazon
- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/ca/p/skin1004/probio-cica-intensive-ampoule/for/mature-skin) — High fit — CA$24.44 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/ca/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — CA$44.95 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/ca/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — CA$31.98 at Amazon
- Moisturizer: [Obagi Hydrate Luxe Moisture-Rich Cream](https://lovi.care/skincare/ca/p/obagi/hydrate-luxe/for/mature-skin) — Superior fit — CA$103.73 at Amazon

## Where to buy

- Amazon.ca: CA$35.98 (https://www.amazon.ca/dp/B07Z182JNK?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- Shoppers Drug Mart: CA$34.49 (https://www.shoppersdrugmart.ca/olay-regenerist-retinol-24-night-facial-serum/p/BB_075609198175?variantCode=075609198175)
Prices checked 11 Oct – 3 Nov 2026.

## Ingredients

Water, Dimethicone, Glycerin, Retinyl Propionate, Caprylic Capric Triglyceride, Retinol, Palmitoyl Pentapeptide-4, Bht, Butylene Glycol, Dimethiconol, Niacinamide, Polysorbate 20, Laureth-4, Laureth-7, Disodium Edta, Dimethicone Crosspolymer, Polyacrylamide, Peg-100 Stearate, Titanium Dioxide, Mica, Tin Oxide, C13-14 Alkane, Dmdm Hydantoin, Iodopropynyl Butylcarbamate, Benzyl Alcohol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/olay/retinol-24-night-serum/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/olay/retinol-24-night-serum/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/olay/retinol-24-night-serum/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/olay/retinol-24-night-serum/for/mature-skin
- France: https://lovi.care/skincare/fr/p/olay/retinol-24-night-serum/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/olay/retinol-24-night-serum/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/olay/retinol-24-night-serum/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/olay/retinol-24-night-serum/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/olay/retinol-24-night-serum/for/mature-skin (this page)
- Australia: https://lovi.care/skincare/au/p/olay/retinol-24-night-serum/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/olay/retinol-24-night-serum/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/olay/retinol-24-night-serum/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/olay/retinol-24-night-serum/for/mature-skin