# numbuzin Pantothenic B5 Active Soothing Cream for sensitive skin

**Lovi Fit: High fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/ca/p/numbuzin/pantothenic-b5-active-soothing-cream/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Brand: [numbuzin](https://lovi.care/skincare/ca/brands/numbuzin)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/ca/best/moisturizers)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for sensitive skin; a few moisturizers fit it even better.

## Why this fit

- This cream is highly suitable for your normal, sensitive skin, as Panthenol and Centella Asiatica Extract work synergistically to provide excellent moisturizing and soothing benefits, effectively calming redness and irritation.
- Niacinamide further supports your skin type by offering anti-inflammatory actions and enhancing the skin barrier.
- The formulation is safe for sensitive skin, containing no harsh ingredients and including soothing components like Centella Asiatica Extract and Panthenol.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ca/p/numbuzin/pantothenic-b5-active-soothing-cream/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/ca/p/numbuzin/pantothenic-b5-active-soothing-cream/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/ca/p/numbuzin/pantothenic-b5-active-soothing-cream/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/ca/p/numbuzin/pantothenic-b5-active-soothing-cream/for/sensitive-skin): High (this page)
- [Acne-prone skin](https://lovi.care/skincare/ca/p/numbuzin/pantothenic-b5-active-soothing-cream/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/ca/p/numbuzin/pantothenic-b5-active-soothing-cream/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/ca/p/numbuzin/pantothenic-b5-active-soothing-cream/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/ca/p/numbuzin/pantothenic-b5-active-soothing-cream/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/ca/p/numbuzin/pantothenic-b5-active-soothing-cream/for/oily-acne-prone-skin): High

## Key ingredients

Pantothenic Acid Vitamin B5, Niacinamide, Centella Asiatica Extract, Aloe Barbadensis Flower Extract, Glycerin

## What the research says

- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Panthenyl triacetate (PTA) demonstrated skin de-acetylation into panthenol, stimulated energetic and synthesis metabolic pathways, and achieved a statistically significant improvement in wound healing after 72 hours compared to saline treatment in human volunteers, outperforming panthenol in long-lasting wound healing action. ([Journal of Cosmetic Science, 2012](https://pubmed.ncbi.nlm.nih.gov/22487447/))
- A comprehensive topical regimen incorporating niacinamide, Pro-Xylane, and panthenol following PicoWay laser treatment decreased transepidermal water loss, increased hydration and skin elasticity, reduced wrinkles and redness, and improved skin tone in 88 Chinese females compared to a standard care control group. ([Lasers in Medical Science, 2026](https://pubmed.ncbi.nlm.nih.gov/42686896/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical 2% niacinamide significantly decreased sebum excretion rate in Japanese individuals and casual sebum levels in Caucasian individuals compared to placebo or baseline. ([Journal of Cosmetic and Laser Therapy, 2006](https://pubmed.ncbi.nlm.nih.gov/16766489/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo. ([Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/))
- Topical aloe vera gel significantly accelerated split-thickness skin graft donor-site healing compared to placebo in 12 patients, but showed no significant difference in pain relief. ([Plastic and Reconstructive Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29649056/))
- Topical application of Aloe vera cream reduced postoperative pain at rest and during defecation, accelerated wound healing at two weeks, and decreased analgesic requirements in patients after open hemorrhoidectomy compared to placebo. ([Journal of Alternative and Complementary Medicine, 2010](https://pubmed.ncbi.nlm.nih.gov/20569031/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))

## What reviewers say

Based on a very large amount of data, this lightweight gel-cream is widely celebrated by users with oily and acne-prone skin for its ability to hydrate without clogging pores or leaving a greasy residue. While it effectively soothes redness and controls excess sebum, users with dry or dehydrated skin often find it lacks sufficient moisture, particularly during colder months.

- Liked: Lightweight gel texture (mostly mentioned)
- Liked: Soothing & calming (often mentioned)
- Disliked: Insufficient moisture (often mentioned)
- Liked: Non-comedogenic (sometimes noted)
- Liked: Sebum/oil control (sometimes noted)
- Disliked: Breakouts/Reactions (rarely noted)
- Disliked: Packaging concerns (rarely noted)

## How to apply

- Use this soothing AM and PM routine every day to keep your normal skin calm. Always remember to apply SPF in the morning after your moisturizer.
- Apply your moisturizer after your toner in the morning, and after your serum in the evening. This step locks in hydration and protects your skin.
- Gently press a small amount of the moisturizer evenly across your face. Avoid rubbing to keep your sensitive skin happy and calm.
- You can apply this gentle formula on dry or slightly damp skin for the best comfort. It works wonderfully on clean skin to soothe redness and irritation.
- Do a patch test before your very first use to check your skin's reaction. Avoid getting the product directly into your eyes .
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes Numbuzin Pantothenic B5 Active Soothing Cream a great fit for sensitive skin?

This cream is a great fit because ingredients like Panthenol and Centella Asiatica Extract work together to keep skin moisturized while helping to calm redness and irritation. Niacinamide also supports your skin by strengthening its barrier, and the formula avoids harsh ingredients to ensure a very safe experience.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Which ingredients make this cream a good fit for sensitive skin?

Pantothenic acid vitamin B5, niacinamide, and centella asiatica extract make this cream a great fit for sensitive skin. These ingredients work together to provide soothing moisture, calm redness and irritation, and strengthen the skin barrier without harsh additives.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### What does Pantothenic Acid do for sensitive skin?

Pantothenic acid helps soothe sensitive skin and keeps it feeling soft by improving moisture and supporting skin barrier repair, but frequent exposure may occasionally cause skin irritation or hypersensitivity in some people.
Sources: [Pharmaceutics, 2026](https://pubmed.ncbi.nlm.nih.gov/42514853/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### What does Niacinamide do for sensitive skin?

Niacinamide helps calm sensitive skin by strengthening the skin barrier and reducing redness and irritation. It is very well tolerated and may improve overall comfort and resilience with regular use.
Sources: [Cutis, 2005](https://pubmed.ncbi.nlm.nih.gov/16209160/), [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/)

### Where does this cream go in a skincare routine for sensitive skin?

This cream goes in the evening routine as a treatment step, applied after your soothing toner and before your moisturizer. It is also suitable for weekly evening routines after your nourishing mask.

### Can I use this cream with retinol, and in what order?

You can use this cream with retinol by applying the cream before or after retinol to help calm redness and keep your skin soft and smooth. Using a barrier-enhancing moisturizer like this one supports your skin and makes it easier to tolerate strong treatments like retinol.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### How often should I use this cream?

This moisturizing treatment is well suited for daily use to keep sensitive skin calm and hydrated. Applying it regularly helps maintain skin comfort and reduces the likelihood of dryness or irritation.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this cream clog pores, cause breakouts or purging for sensitive skin?

This cream is unlikely to cause breakouts or clogged pores for sensitive skin, as it features a safe formulation with a low rate of complaints and soothing ingredients like Centella Asiatica Extract and Panthenol. These components help calm irritation while keeping the skin hydrated.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Can I use this cream around the eyes or on my body?

This moisturizing treatment is well-suited for sensitive skin around the eyes and on the body because its soothing ingredients are very safe. It helps keep thin or sensitive areas comfortable and calm without irritation.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for sensitive skin

- [SKIN1004 Madagascar Centella Probio-Cica Enrich Cream](https://lovi.care/skincare/ca/p/skin1004/madagascar-centella-probio-cica-enrich-cream/for/sensitive-skin) — Superior fit — CA$30.98 at Amazon
- [COSRX Advanced Snail 96 Mucin Power Essence](https://lovi.care/skincare/ca/p/cosrx/advanced-snail-96-mucin-power-essence/for/sensitive-skin) — Superior fit — CA$24.99 at Amazon
- [COSRX Advanced Snail 92 All in One Cream](https://lovi.care/skincare/ca/p/cosrx/advanced-snail-92-all-in-one-cream/for/sensitive-skin) — Superior fit — CA$26.18 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/ca/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — CA$44.95 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/ca/p/clarins/soothing-toning-lotion/for/sensitive-skin) — Superior fit — CA$49.00 at Amazon
- Moisturizer with Sun Protection: [Torriden DIVE-IN Mild Sunscreen](https://lovi.care/skincare/ca/p/torriden/dive-in-mild-sunscreen/for/sensitive-skin) — Superior fit — CA$27.34 at Amazon

## Where to buy

- Amazon.ca: CA$34.99 (https://www.amazon.ca/dp/B0HLMDYJXD?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Water, Butylene Glycol, Glycerin, Niacinamide, Cetyl Ethylhexanoate, Dicaprylyl Carbonate, 1,2-Hexanediol, Pentylene Glycol, Vinyl Dimethicone, Centella Asiatica Extract, Caprylyl Methicone, Erythritol, Panthenol, Hydroxyethyl Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Dimethiconol, Polymethylsilsesquioxane, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Chlorella Vulgaris Extract, Glucose, Tromethamine, Silica, Fructooligosaccharides, Fructose, Sophora Angustifolia Root Extract, Ethylhexylglycerin, Xanthan Gum, Sodium Phytate, Glyceryl Acrylate Acrylic Acid Copolymer, Caprylic Capric Triglyceride, Melia Azadirachta Leaf Extract, Melia Azadirachta Flower Extract, Coccinia Indica Fruit Extract, Hydrogenated Lecithin, Ocimum Sanctum Leaf Extract, Tocopherol, Curcuma Longa Root Extract, Aloe Barbadensis Flower Extract, Solanum Melongena Fruit Extract, Decyl Glucoside, Corallina Officinalis Extract, Pantothenic Acid, Polyglyceryl-4 Caprate, Polyglyceryl-6 Caprylate, Camellia Sinensis Leaf Extract, Centella Asiatica Leaf Extract, Cladosiphon Okamuranus Extract, Willow Bark Extract, Houttuynia Cordata Extract, Coffea Arabica Seed Extract Coffee Seed Extract, Bergamot Leaf Extract, Pinus Densiflora Leaf Extract, Alpha-Arbutin, Zinc Pca, Argania Spinosa Kernel Oil, Methyl Diisopropyl Propionamide, Sesamum Indicum Seed Oil, Serenoa Serrulata Fruit Extract, Beta-Sitosterol, Glycyrrhiza Glabra Root Extract Licorice Root Extract
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/numbuzin/pantothenic-b5-active-soothing-cream/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/numbuzin/pantothenic-b5-active-soothing-cream/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/numbuzin/pantothenic-b5-active-soothing-cream/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/numbuzin/pantothenic-b5-active-soothing-cream/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/numbuzin/pantothenic-b5-active-soothing-cream/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/numbuzin/pantothenic-b5-active-soothing-cream/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/numbuzin/pantothenic-b5-active-soothing-cream/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/numbuzin/pantothenic-b5-active-soothing-cream/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/numbuzin/pantothenic-b5-active-soothing-cream/for/sensitive-skin (this page)
- Australia: https://lovi.care/skincare/au/p/numbuzin/pantothenic-b5-active-soothing-cream/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/numbuzin/pantothenic-b5-active-soothing-cream/for/sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/numbuzin/pantothenic-b5-active-soothing-cream/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/numbuzin/pantothenic-b5-active-soothing-cream/for/sensitive-skin