# numbuz:n No.3 Skin Softening Serum for skin with dark spots

**Lovi Fit: High fit for skin with dark spots.**
Normal Skin Fit: High · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/ca/p/numbuz-n/no-3-skin-softening-serum/for/dark-spots

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Brand: [numbuz:n](https://lovi.care/skincare/ca/brands/numbuz-n)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/ca/best/moisturizers)

This fit is calculated for the concerns frequently associated with dark spots: hyperpigmentation, sun spots, and uneven skin tone. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best moisturizers for skin with dark spots.

## Why this fit

- This serum offers high suitability for your normal skin, as Bifida Lysate Ferment and Galactomyces Ferment Filtrate enhance barrier resilience and provide humectant action. Niacinamide and Adenosine also contribute to improving skin tone and texture, addressing your pigmentation concerns.
- The formulation includes Squalane and Panthenol, which offer additional moisturizing and soothing benefits, complementing the primary ingredients.
- The product is safe for your skin, with no reported risks of irritation due to its gentle formulation and the inclusion of soothing agents.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ca/p/numbuz-n/no-3-skin-softening-serum/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/ca/p/numbuz-n/no-3-skin-softening-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/ca/p/numbuz-n/no-3-skin-softening-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/ca/p/numbuz-n/no-3-skin-softening-serum/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/ca/p/numbuz-n/no-3-skin-softening-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/ca/p/numbuz-n/no-3-skin-softening-serum/for/dark-spots): High (this page)
- [Mature skin](https://lovi.care/skincare/ca/p/numbuz-n/no-3-skin-softening-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/ca/p/numbuz-n/no-3-skin-softening-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/ca/p/numbuz-n/no-3-skin-softening-serum/for/oily-acne-prone-skin): High

## Key ingredients

Bifida Lysate Ferment, Galactomyces Ferment Filtrate, Niacinamide, Sodium Hyaluronate, Squalane

## What the research says

- Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer. ([The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/))
- Topical application of a disodium adenosine monophosphate-based formulation reduced wrinkles and hyperpigmentation while improving hydration, barrier function, skin lifting, and epidermal turnover in female participants. ([International Journal of Molecular Sciences, 2026](https://pubmed.ncbi.nlm.nih.gov/42278371/))
- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/))
- Topical treatment of nicotinamide, alone or in combination with other active ingredients, reduces the progression of skin aging and hyperpigmentation in clinical trials while being well tolerated. ([Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/))
- Topical application of Bifida Ferment Lysate strengthens the skin barrier function by upregulating barrier and antimicrobial peptide genes, exhibiting strong antioxidant properties, and decreasing inflammatory cytokine secretion in vitro. ([Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37218728/))
- A combination serum containing galactomyces ferment filtrate, dexpanthenol, and Centella asiatica effectively treated post-acne hyperpigmentation in subjects with colored skin by significantly increasing lightness scores in Fitzpatrick skin type V and reducing the melanin index in Fitzpatrick skin type IV compared to placebo. ([Skinmed, 2021](https://pubmed.ncbi.nlm.nih.gov/33938432/))
- Application of Galactomyces ferment filtrate skin care formula significantly reduced the net values and daily fluctuation of facial pore area, roughness, and redness in young Japanese women. ([Journal of Clinical Medicine, 2021](https://pubmed.ncbi.nlm.nih.gov/34198790/))
- Galactomyces ferment filtrate promotes epidermal interconnectivity, barrier development, cell adhesion, keratinocyte differentiation and proliferation, and protects cellular bioenergetics against stress in keratinocytes and ex vivo skin explants compared to untreated controls. ([International Journal of Cosmetic Science, 2024](https://pubmed.ncbi.nlm.nih.gov/38924095/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))

## What reviewers say

Based on a very large amount of data, this serum is highly effective at softening and smoothing skin, providing a radiant glow and deep hydration, with many users achieving a 'glass skin' appearance. However, a moderate number of users report breakouts and fungal acne flare-ups, while a low number experience irritation or find the finish sticky. This summary should be definitely taken into account.

- Liked: Softens skin (mostly mentioned)
- Liked: Deeply hydrating (often mentioned)
- Liked: Improves radiance (often mentioned)
- Liked: Elegant texture (sometimes noted)
- Disliked: Causes breakouts (sometimes noted)
- Disliked: Causes irritation (rarely noted)
- Disliked: No results (rarely noted)
- Disliked: Sticky finish (rarely noted)

## How to apply

- Could be used as part of your AM and PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
- Apply this moisturizer after your cleanser and toner, right before your morning SPF.
- Gently press a small amount of the moisturizer into your skin. Avoid rubbing it too hard so it absorbs nicely.
- For the best moisture, you can apply it when your skin is slightly damp. This helps your skin stay soft and happy.
- Remember to avoid the eye area when applying. Always do a patch test before your first use.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes numbuz:n No.3 Skin Softening Serum a great fit for skin with dark spots?

This serum is a great fit for skin with dark spots because Niacinamide and Adenosine help improve skin tone and texture by addressing pigmentation concerns. Bifida Lysate Ferment and Galactomyces Ferment Filtrate further support the skin by enhancing barrier resilience and keeping it hydrated.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [International Journal of Molecular Sciences, 2026](https://pubmed.ncbi.nlm.nih.gov/42278371/)

### Which ingredients make this serum a good fit for skin with dark spots?

Niacinamide and Adenosine make this serum a great fit for skin with dark spots by helping improve skin tone and texture. Niacinamide significantly decreases dark spots and increases skin lightness by stopping pigment transfer.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [International Journal of Molecular Sciences, 2026](https://pubmed.ncbi.nlm.nih.gov/42278371/)

### What does Bifida Ferment Lysate do for skin with dark spots?

Bifida Ferment Lysate helps strengthen the skin barrier and calm irritation, making it a supportive addition for skin with dark spots. It works to keep your skin balanced and protected against daily stress, which may prevent new marks from forming.
Sources: [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37218728/), [Experimental Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/19624730/)

### What does Galactomyces Ferment Filtrate do for skin with dark spots?

Galactomyces Ferment Filtrate helps fade dark spots and uneven pigmentation while making skin look brighter and smoother with regular daily use. Studies show that using it consistently can significantly reduce hyperpigmented spots and improve overall skin tone.
Sources: [Journal of Clinical Medicine, 2023](https://pubmed.ncbi.nlm.nih.gov/36769815/), [Skinmed, 2021](https://pubmed.ncbi.nlm.nih.gov/33938432/)

### Where does this serum go in a skincare routine for skin with dark spots?

This serum goes in the evening routine after cleansing and before moisturizing, which keeps things simple and protects against sun exposure. Niacinamide helps fade dark spots while soothing ingredients keep the skin calm.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/)

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first to keep your skin soft and calm while helping retinol work smoothly. The gentle formulation with soothing and moisturizing ingredients helps lower the risk of unwanted dryness or irritation.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use this serum?

You can use this serum in the evening as part of your routine for dark spots, and some people may also use it in the morning or twice a day. Daily application helps improve skin tone, texture, and moisture while keeping your skin calm.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this serum clog pores, cause breakouts or purging for skin with dark spots?

This serum is a great fit for skin with dark spots, but reviewers moderately complain that it may cause breakouts. Its gentle formula is unlikely to cause irritation, though reactions vary by individual.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/)

### Can I use this serum around the eyes or on my body?

Yes, you can use this serum around the eyes and on your body, as its gentle ingredients are very safe for the skin. However, keep in mind that skin thickness varies significantly across body regions, with the eyelids being among the thinnest areas.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for skin with dark spots

- [Torriden DIVE-IN Low Molecular Hyaluronic Acid Serum](https://lovi.care/skincare/ca/p/torriden/dive-in-low-molecular-hyaluronic-acid-serum/for/dark-spots) — High fit — CA$21.81 at Amazon
- [MISSHA Super Aqua Ultra Hyalron Ampoule](https://lovi.care/skincare/ca/p/missha/super-aqua-ultra-hyalron-ampoule/for/dark-spots) — Average fit — CA$37.99 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/ca/p/cerave/foaming-facial-cleanser/for/dark-spots) — Superior fit — CA$20.96 at Amazon
- Hydrating Toner: [Pyunkang Yul Calming Deep Moisture Toner](https://lovi.care/skincare/ca/p/pyunkang-yul/calming-deep-moisture-toner/for/dark-spots) — Superior fit — CA$23.99 at Amazon
- SPF: [Torriden DIVE-IN Mild Sunscreen](https://lovi.care/skincare/ca/p/torriden/dive-in-mild-sunscreen/for/dark-spots) — Superior fit — CA$27.34 at Amazon

## Where to buy

- Amazon.ca: CA$39.99 (https://www.amazon.ca/dp/B0GBW9SPCX?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
Prices checked 3 Nov 2026.

## Ingredients

Bifida Lysate Ferment, Galactomyces Ferment Filtrate, Butylene Glycol, Methyl Gluceth-20, Water, Niacinamide, Peg-90, 1,2-Hexanediol, Glycerin, Squalane, Alteromonas Extract Ferment, Silk Extract, Goat Extract Milk, Sodium Hyaluronate, Panthenol, Adenosine, Glycereth-26, Xanthan Gum, Polyglyceryl-3 Distearate, Glyceryl Stearate Se, Glyceryl Stearate Citrate, Polyglyceryl-3 Methylglucose Distearate, Carbomer, Tromethamine, Ethylhexylglycerin, Caprylyl Glycol, Tropolone, Disodium Edta
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/numbuz-n/no-3-skin-softening-serum/for/dark-spots
- United Kingdom: https://lovi.care/skincare/uk/p/numbuz-n/no-3-skin-softening-serum/for/dark-spots
- Ireland: https://lovi.care/skincare/ie/p/numbuz-n/no-3-skin-softening-serum/for/dark-spots
- Germany: https://lovi.care/skincare/de/p/numbuz-n/no-3-skin-softening-serum/for/dark-spots
- France: https://lovi.care/skincare/fr/p/numbuz-n/no-3-skin-softening-serum/for/dark-spots
- Italy: https://lovi.care/skincare/it/p/numbuz-n/no-3-skin-softening-serum/for/dark-spots
- Netherlands: https://lovi.care/skincare/nl/p/numbuz-n/no-3-skin-softening-serum/for/dark-spots
- Spain: https://lovi.care/skincare/es/p/numbuz-n/no-3-skin-softening-serum/for/dark-spots
- Canada: https://lovi.care/skincare/ca/p/numbuz-n/no-3-skin-softening-serum/for/dark-spots (this page)
- Australia: https://lovi.care/skincare/au/p/numbuz-n/no-3-skin-softening-serum/for/dark-spots
- Singapore: https://lovi.care/skincare/sg/p/numbuz-n/no-3-skin-softening-serum/for/dark-spots
- Saudi Arabia: https://lovi.care/skincare/sa/p/numbuz-n/no-3-skin-softening-serum/for/dark-spots
- United Arab Emirates: https://lovi.care/skincare/ae/p/numbuz-n/no-3-skin-softening-serum/for/dark-spots