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NIOD Modulating Glucosides for dry sensitive skin

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes

NIOD Modulating Glucosides

High

  • HighDry Skin Fit
  • HighEffectiveness
  • HighSafety

One of the best serums for dry sensitive skin.

This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.

Page built Nov 8, 2026How the Fit score works

Lovi Assistant explains

  • Offers excellent soothing and anti-redness effects for your sensitive dry skin, as Bisabolol and Tasmannia Lanceolata Leaf Extract Fruit work to calm irritation and reduce redness.
  • The inclusion of Squalane and Glycerin provides essential hydration, addressing your dry or flaky skin concerns by smoothing intercellular lipids and drawing water into the skin.
  • This formula is safe for your sensitive skin, containing no harsh ingredients and featuring soothing components that minimize the risk of irritation.

How to apply

  • Use this PM routine for your evening skincare. Start using the serum 3 times a week and increase to daily use if your skin feels comfortable.
  • Apply the serum after cleansing and toner, but right before your moisturizer. This step locks in deep hydration for dry skin.
  • Gently press 2-3 drops of the serum into your skin using your palms. Let it absorb completely for a minute ⏱ before applying your next product.
  • Since your skin is sensitive, apply the serum on completely dry skin for better tolerance and less irritation.
  • Avoid the sensitive eye area during application. Always do a patch test before your first use to ensure your skin reacts well.

People Say

★4.8Overall rating based on 400+ reviews

This serum is highly praised for its ability to calm sensitive, reactive, and irritated skin, with users frequently reporting significant improvements in redness, stinging, and compromised skin barriers. It is a popular choice for those recovering from aesthetic treatments or harsh active ingredients. Some users with normal skin may find the benefits less noticeable or the texture slightly heavy.

Highlights

  • Calms sensitive skin Mostly Mentioned
    • “Like medicine to irritated skin.”
    • “Great for sensitive, reactive skin.”
    • “Helps quiet sensations of stinging and itching.”
  • Reduces skin redness Often Mentioned
    • “Visibly reduced redness for a more even tone.”
    • “Calms redness and stinging.”
    • “It really did wonders in soothing skin and reducing redness.”
  • Buffers active irritation Sometimes Noted
    • “Helps minimise the side effects of retinoids.”
    • “Buffers retinoid/acid irritation.”
    • “Reason my skin had been so calm while I was on Roaccutane.”
  • Strengthens skin barrier Sometimes Noted
    • “Saved my skin barrier from beyond hope.”
    • “Strengthens skin barrier integrity over time.”
    • “Especially helpful when my barrier is compromised.”
  • Inconvenient packaging Sometimes Noted
    • “Dropper bottle is messy to use.”
    • “Not my favorite type of packaging.”
    • “Why doesn't it come with a pump?”
  • Subtle for normal skin Sometimes Noted
    • “If you have normal skin, benefits may not be apparent.”
    • “I did not notice any improvement.”
  • Can cause breakouts Rarely Noted
    • “It broke me out almost instantly.”
    • “Heavy going on my face.”
  • Unappealing scent Rarely Noted
    • “Strong nutty scent.”
    • “A bit like paint.”
    • “Has a bit of a medicinal smell.”

Sources: lovi.care, niod.com, skinsort.com, dermapproved.com, drrachelho.com, daniellesbeautyblog.com, and more

Questions and answers

What makes NIOD Modulating Glucosides a great fit for dry sensitive skin?

NIOD Modulating Glucosides is a great fit because ingredients like bisabolol and Tasmanian pepperberry calm irritation and reduce redness. Meanwhile, squalane and glycerin draw in water and smooth dry skin, and the formula contains no harsh ingredients to keep your sensitive skin safe from irritation.

Clinical, Cosmetic and Investigational Dermatology, 2017

Which ingredients make this treatment a good fit for dry sensitive skin?

This treatment is a great fit for your dry sensitive skin because it contains bisabolol and tasmannia lanceolata leaf extract fruit to calm irritation and reduce redness, alongside squalane and glycerin to draw in moisture and smooth dry areas.

Clinical, Cosmetic and Investigational Dermatology, 2017

What do Glucosides do for dry sensitive skin?

Glucosides help keep dry sensitive skin soft and smooth by boosting moisture levels and reducing water loss. They improve how well the skin barrier holds onto hydration, which helps calm visible dryness and rough spots.

Skin Pharmacology and Physiology, 2012The Journal of Clinical and Aesthetic Dermatology, 2012

What does Squalane do for dry sensitive skin?

Squalane helps keep dry sensitive skin soft and smooth by locking in moisture and calming irritation without causing flare-ups. It is unlikely to cause redness or discomfort, making it a gentle choice that supports the skin barrier. This type of skin needs ingredients that deeply hydrate and soothe, such as plant oils and antioxidants.

International Journal of Molecular Sciences, 2017Molecules, 2009

Where does this treatment go in a skincare routine for dry sensitive skin?

This treatment goes in your evening routine, applied after your cleanser and soothing toner and before your moisturizer. Putting treatments in the evening helps keep your skin safe around sun exposure while providing effective care.

Can I use this treatment with retinol, and in what order?

You can use this treatment with retinol by applying it after your retinol to help calm irritation and keep dry skin comfortable. Its soothing ingredients and gentle formula minimize the risk of redness when pairing active products.

How often should I use this treatment?

Use this treatment in your evening routine. It is a great fit for dry sensitive skin because it helps calm irritation and provides essential hydration.

Clinical, Cosmetic and Investigational Dermatology, 2017

Can this treatment clog pores, cause breakouts or purging for dry sensitive skin?

This treatment is unlikely to clog pores or cause breakouts for dry sensitive skin. Reviewers rarely report breakouts from this formula, and its soothing ingredients help keep irritation low.

Is this treatment fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (benzyl alcohol).

What the research says

Ingredients

Water, Squalane, Isodecyl Neopentanoate, Glycerin, Caprylic Capric Triglyceride, Pentylene Glycol, Propanediol, Hexyldecanol, Bisabolol, Butylene Glycol, Epigallocatechin Gallatyl Glucoside, Rosmarinyl Glucoside, Caffeyl Glucoside, Gallyl Glucoside, Tetrasodium Tetracarboxymethyl Naringeninchalcone, Hydroxymethoxyphenyl Decanone, 4-T-Butylcyclohexanol, Cetylhydroxyproline Palmitamide, Hydroxyphenyl Propamidobenzoic Acid, Palmitoyl Tripeptide-8, Superoxide Dismutase, Sodium Pca, Pca, Arginine, Glycine, Alanine, Serine, Valine, Isoleucine, Proline, Threonine, Histidine, Phenylalanine, Aspartic Acid, Sodium Lactate, Mirabilis Jalapa Callus Extract, Tasmannia Lanceolata Leaf Extract Fruit, Zingiber Officinale Root Extract, Curculigo Orchioides Root Extract, Isochrysis Galbana Extract, Brassica Campestris Sterols, Stearic Acid, Dextran, Isoceteth-20, Polyacrylate Crosspolymer-6, Xanthan Gum, Tocopherol, Propyl Gallate, Tromethamine, Dehydroacetic Acid, 1,2-Hexanediol, Benzyl Alcohol, Phenoxyethanol, Caprylyl Glycol

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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