# Murad Retinol Youth Renewal Night Cream for combination skin

**Lovi Fit: High fit for combination skin.**
Combination Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/ca/p/murad/retinol-youth-renewal-night-cream/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Brand: [Murad](https://lovi.care/skincare/ca/brands/murad)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/ca/best/moisturizers)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for combination skin; a few moisturizers fit it even better.

## Why this fit

- This formulation offers high suitability for your combination skin, as niacinamide helps regulate sebum production and retinol aids in desquamation, addressing your oily shine concerns.
- The presence of sodium hyaluronate and glycerin provides essential hydration and soothing benefits, supporting overall skin health.
- The product is safe for your skin, with no reported risks of irritation due to the absence of harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ca/p/murad/retinol-youth-renewal-night-cream/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/ca/p/murad/retinol-youth-renewal-night-cream/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/ca/p/murad/retinol-youth-renewal-night-cream/for/combination-skin): High (this page)
- [Sensitive skin](https://lovi.care/skincare/ca/p/murad/retinol-youth-renewal-night-cream/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/ca/p/murad/retinol-youth-renewal-night-cream/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/ca/p/murad/retinol-youth-renewal-night-cream/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/ca/p/murad/retinol-youth-renewal-night-cream/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/ca/p/murad/retinol-youth-renewal-night-cream/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/ca/p/murad/retinol-youth-renewal-night-cream/for/oily-acne-prone-skin): High

## Key ingredients

Retinol, Niacinamide, Sodium Hyaluronate, Hydrolyzed Yeast Extract, Glycerin

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical 0.4% retinol significantly increased epidermal thickness, dermal vascularity, and extracellular matrix production by stimulating keratinocyte proliferation, endothelial cell proliferation, and fibroblast activation in naturally aged human skin compared to vehicle. ([International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/))
- Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging. ([The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/))
- Silicone particles encapsulating retinol increased its half-life by 9-fold and yielded 12-23% lower skin irritation in human subjects compared to Microsponge particles while maintaining biological activity. ([Journal of Controlled Release, 2018](https://pubmed.ncbi.nlm.nih.gov/29604311/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical moisturizers improved skin barrier function and surface moisture, while a postbiotic moisturizer with yeast extract uniquely supported microbiome balance and modulated biomarkers of skin barrier, structure, and inflammation in participants and ex vivo explants exposed to environmental aggressors. ([Journal of Clinical Medicine, 2023](https://pubmed.ncbi.nlm.nih.gov/37763018/))
- A maintenance therapy with a cosmeceutical formulation containing hydroxyphenoxy propionic acid, ellagic acid, yeast extract, and salicylic acid over 20 weeks significantly improved even skin tone, spot intensity, spot size, and overall hyperpigmentation in 33 healthy subjects with moderate facial dyspigmentation. ([Journal of Drugs in Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25844613/))
- A methanol yeast extract increases proliferation and migration while decreasing entrance into senescence and apoptosis phases in 3T3 fibroblast cells. ([Journal of Cosmetic Science, 2014](https://pubmed.ncbi.nlm.nih.gov/25898765/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))

## What reviewers say

Based on a very large amount of data, users report this night cream effectively smooths fine lines and improves skin texture without the harsh irritation often associated with retinol. Many praise its hydrating, lightweight formula for creating a plump and radiant complexion, though a subset of users with sensitive skin experienced dryness or breakouts.

- Liked: Gentle and hydrating (mostly mentioned)
- Liked: Luxurious texture (often mentioned)
- Liked: Visible anti-aging (often mentioned)
- Liked: Radiance and glow (sometimes noted)
- Disliked: High price point (sometimes noted)
- Disliked: Strong fragrance (sometimes noted)
- Disliked: Adverse reactions (rarely noted)
- Disliked: Packaging issues (rarely noted)

## How to apply

- Use this moisturizer in your AM and PM routine every day to control shine. Always pair with SPF in the morning.
- Apply this moisturizer after your cleanser and toner, right before your morning SPF.
- Gently press a small amount of the moisturizer into your skin and avoid harsh rubbing. Let it ⏳absorb for a minute.
- Apply the moisturizer on slightly damp skin to help it lock in moisture better. This keeps your combination skin balanced.
- Avoid the eye area when applying the moisturizer. Do a patch test before your first use.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes Murad Retinol Youth Renewal Night Cream a great fit for combination skin?

This cream is a great fit for your combination skin because niacinamide helps balance oily shine while retinol smooths the surface. At the same time, sodium hyaluronate and glycerin bring essential hydration to keep your skin feeling soft and comfortable.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this cream a good fit for combination skin?

This cream is a great fit for combination skin because niacinamide helps balance oily shine while retinol smooths the skin. Additionally, sodium hyaluronate and glycerin provide essential hydration to keep the skin soft and healthy.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Retinol do for combination skin?

Retinol helps smooth fine lines, even out skin tone, and improve firmness in combination skin. It works by encouraging faster skin renewal and boosting collagen, though it may occasionally cause mild dryness or scaling while your skin adjusts.
Sources: [Archives of Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17515510/), [The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/)

### What does Niacinamide do for combination skin?

Niacinamide helps balance oily areas by reducing excess shine and pore size while keeping dry patches hydrated and smooth. It also works to calm redness and even out skin tone, making it very suitable for combination skin.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### Where does this cream go in a skincare routine for combination skin?

This cream goes in the evening routine as a treatment step, applied after cleansing and before moisturizing. It is a great fit for your combination skin because niacinamide helps regulate sebum production and retinol aids in skin renewal.
Sources: [International Journal of Cosmetic Science, 2020](https://pubmed.ncbi.nlm.nih.gov/31461548/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use this cream with vitamin C, and in what order?

You can use this cream with vitamin C by applying your vitamin C product in the morning and saving this retinol cream for your evening routine. Using them at different times of the day helps prevent irritation while keeping your skin smooth and glowing.

### How often should I use this cream?

You can use this moisturizing treatment in your evening routine as part of your regular skincare steps. Daily application helps improve skin texture and hydration while managing oily shine.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Journal of Drugs in Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/26151786/)

### Can this cream clog pores, cause breakouts or purging for combination skin?

This cream is unlikely to clog pores or cause breakouts on combination skin because niacinamide helps regulate oil and retinol aids in skin renewal. It is generally safe for your skin type, with very low chances of adverse reactions.

### Can I use this cream around the eyes or on my body?

This cream is generally intended for facial use, so you should check the product label for specific guidance on applying it around the eyes or on the body. The delicate skin around the eyes and certain areas of the body may require specialized formulas to prevent irritation.

### Is this cream fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (citronellol and parfum). Cetyl alcohol and oleyl alcohol are fatty alcohols, which soften the skin.

## Alternatives for combination skin

- [Drunk Elephant Protini Polypeptide Cream](https://lovi.care/skincare/ca/p/drunk-elephant/protini-polypeptide-cream/for/combination-skin) — Superior fit — CA$95.99 at Amazon
- [The Ordinary Natural Moisturizing Factors + HA](https://lovi.care/skincare/ca/p/the-ordinary/natural-moisturizing-factors-ha/for/combination-skin) — High fit — CA$16.20 at Amazon
- [Allies of Skin Peptides & Antioxidants Firming Daily Treatment](https://lovi.care/skincare/ca/p/allies-of-skin/peptides-and-antioxidants-firming-daily-treatment/for/combination-skin) — High fit — CA$98.99 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/ca/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — CA$44.95 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/ca/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — CA$37.60 at Amazon
- SPF: [CeraVe AM Facial Moisturizing Lotion](https://lovi.care/skincare/ca/p/cerave/am-facial-moisturizing-lotion-spf-30/for/combination-skin) — Superior fit — CA$20.96 at Amazon

## Where to buy

- Amazon.ca: CA$41.00 (https://www.amazon.ca/dp/B0CNG2PF6Q?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Water, Isostearyl Hydroxystearate, Niacinamide, Propanediol, Caprylic Capric Triglyceride, C14-22 Alcohols, Polymethylsilsesquioxane, Dimethicone, Cetyl Alcohol, Glyceryl Stearate, Hydrolyzed Yeast Extract, Isopropyl Palmitate, Retinol, Retinyl Propionate, Oleyl Alcohol, Sodium Hyaluronate, Serine, Hexyldecanol, Glycine Soja Extract Soybean Extract, Tocopheryl Acetate, Glycine Soja Soybean Sterols, Urea, Yeast Amino Acids, Trehalose, Inositol, Taurine, Betaine, Glycerin, Polyglucuronic Acid, C12-20 Alkyl Glucoside, Yam Root Extract, Pentylene Glycol, Glyceryl Polyacrylate, Algin, Caprylyl Glycol, Swertia Chirata Extract, Lecithin, Pullulan, Disodium Phosphate, Potassium Phosphate, Peg-75 Stearate, Ceteth-20, Steareth-20, Cetyl Hydroxyethylcellulose, Phenoxyethanol, Ethylhexylglycerin, Picolinamide, Disodium Edta, Sodium Hydroxide, Hexylene Glycol, Sodium Benzotriazolyl Butylphenol Sulfonate, Ammonium Acryloyldimethyltaurate Vp Copolymer, Yellow 5 Ci 19140, Red 4 Ci 14700, Alpha-Isomethyl Ionone, Citronellol, Parfum
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/murad/retinol-youth-renewal-night-cream/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/murad/retinol-youth-renewal-night-cream/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/murad/retinol-youth-renewal-night-cream/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/murad/retinol-youth-renewal-night-cream/for/combination-skin
- France: https://lovi.care/skincare/fr/p/murad/retinol-youth-renewal-night-cream/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/murad/retinol-youth-renewal-night-cream/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/murad/retinol-youth-renewal-night-cream/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/murad/retinol-youth-renewal-night-cream/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/murad/retinol-youth-renewal-night-cream/for/combination-skin (this page)
- Australia: https://lovi.care/skincare/au/p/murad/retinol-youth-renewal-night-cream/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/murad/retinol-youth-renewal-night-cream/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/murad/retinol-youth-renewal-night-cream/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/murad/retinol-youth-renewal-night-cream/for/combination-skin