# Mother Science Molecular Hero Serum for oily skin

**Lovi Fit: Average fit for oily skin.**
Oily Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/ca/p/mother-science/molecular-hero-serum/for/oily-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Brand: [Mother Science](https://lovi.care/skincare/ca/brands/mother-science)
Category: [Serums and treatments](https://lovi.care/skincare/ca/best/serums)

This fit is calculated for the concerns frequently associated with oily skin: shine, enlarged pores, blackheads, and blemishes. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for oily skin; other serums fit it better.

## Why this fit

- Offers moderate benefits for your oily skin, as niacinamide and rhododendron ferrugineum extract provide antioxidant protection and help regulate oil production, though they do not directly address oily shine.
- Sodium hyaluronate and bisabolol offer general hydration and soothing effects, which are supportive but not primary for your main concern.
- The product is safe for your oily skin, with no risks of irritation due to the absence of harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ca/p/mother-science/molecular-hero-serum/for/oily-skin): Average (this page)
- [Dry skin](https://lovi.care/skincare/ca/p/mother-science/molecular-hero-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/ca/p/mother-science/molecular-hero-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/ca/p/mother-science/molecular-hero-serum/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/ca/p/mother-science/molecular-hero-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/ca/p/mother-science/molecular-hero-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/ca/p/mother-science/molecular-hero-serum/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/ca/p/mother-science/molecular-hero-serum/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/ca/p/mother-science/molecular-hero-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Malassezin, Niacinamide, Sodium Hyaluronate, Glycerin, Bisabolol

## What the research says

- Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/))
- Hyaluronic acid extracts are safe and efficacious products for skin repair when used in tissue regeneration alone or in combination with herbal or Western medicine. ([Journal of Pharmacy & Pharmaceutical Sciences, 2015](https://pubmed.ncbi.nlm.nih.gov/25877441/))
- Topical treatment of nicotinamide, alone or in combination with other active ingredients, reduces the progression of skin aging and hyperpigmentation in clinical trials while being well tolerated. ([Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/))
- Topical malassezin applied twice daily decreased epidermal melanin and reduced melanocyte dendricity in seven subjects with facial hyperpigmentation at 8 and 14 weeks, with pigmentation returning to baseline by 22 weeks. ([Journal of Drugs in Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35133118/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Application of an alpha-bisabolol-containing cream produced a significant skin-lightening effect in pigmented skin compared to a vehicle control in the majority of female subjects after 8 weeks. ([International Journal of Cosmetic Science, 2010](https://pubmed.ncbi.nlm.nih.gov/20642768/))
- The combination of allantoin, bisabolol, D-panthenol and dipotassium glycyrrhizinate reduces UVB-induced PGE2, inflammatory cytokines, and mitochondrial superoxide in human epidermal keratinocytes. ([International Journal of Cosmetic Science, 2024](https://pubmed.ncbi.nlm.nih.gov/38433250/))

## Why other serums fit oily skin better

- A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38366684/))
- Niacinamide and ferulic acid incorporated in a stable multiple emulsion successfully reduced melanin, sebum, and skin erythema while improving skin elasticity and hydration in human skin compared to a placebo. ([BioMed Research International, 2022](https://pubmed.ncbi.nlm.nih.gov/35342760/))

## What reviewers say

This serum is highly effective at fading dark spots and hyperpigmentation, leading to a brighter and more even complexion. Some users find the product to be expensive, and a few have noted occasional dryness or a grainy texture.

- Liked: Fades dark spots (mostly mentioned)
- Liked: Brightens skin (often mentioned)
- Disliked: Expensive product (often mentioned)
- Liked: Gentle formula (sometimes noted)
- Liked: Lightweight texture (sometimes noted)
- Disliked: Causes dryness (rarely noted)
- Disliked: Grainy texture (rarely noted)
- Disliked: Slow results (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week and build up to daily use if your skin tolerates it well.
- Apply the serum after cleansing and toning, but right before your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin. Let it absorb ⏱ for a minute before applying the next product.
- Apply the serum on clean and dry skin since your skin is not sensitive and you want to target oily shine. This helps control excess oil throughout the night.
- Avoid the delicate eye area and do a patch test before using the serum for the very first time.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Molecular Hero Serum work for oily skin?

Mother Science Molecular Hero Serum works reasonably well for oily skin by offering moderate benefits like antioxidant protection and oil regulation, though it does not directly target oily shine. To better manage oily skin, a treatment of this type needs ingredients like niacinamide, zinc PCA, and ferulic acid that control excess oil and pores while maintaining a healthy glow.

### Which ingredients make this serum a good fit for oily skin?

Niacinamide and rhododendron ferrugineum extract make this serum a fit for your oily skin by providing antioxidant protection and helping regulate oil production, while sodium hyaluronate and bisabolol offer general hydration and soothing effects. To fit oily skin even better, a treatment of this type needs ingredients that control sebum production and manage oily shine, such as ferulic acid and zinc PCA, along with barrier-supporting ceramides.

### What does Malassezin do for oily skin?

Malassezin is unlikely to directly treat oily skin, but it helps brighten skin and fade dark patches with a safety profile comparable to standard treatments. For oily skin specifically, a product of this type needs lightweight hydrators and oil-balancing ingredients to manage shine while improving tone.
Sources: [Journal of Drugs in Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41493251/), [Chembiochem, 2005](https://pubmed.ncbi.nlm.nih.gov/15812864/)

### What does Niacinamide do for oily skin?

Niacinamide helps balance oily skin by significantly reducing excess oil production and shine. It is well tolerated and may improve skin texture without clogging pores.
Sources: [Journal of Cosmetic and Laser Therapy, 2006](https://pubmed.ncbi.nlm.nih.gov/16766489/), [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### Where does this serum go in a skincare routine for oily skin?

This treatment serum goes in the evening routine after cleansing and before moisturizing, though some can also be used in the morning or twice a day. It is safe for oily skin and is unlikely to cause irritation.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the treatment in your evening routine after cleansing and toning, followed by your moisturizer. This product is safe for your skin with no risks of irritation due to the absence of harsh ingredients.

### How often should I use this serum?

You can use this treatment in the evening as part of your routine. It is unlikely to irritate your oily skin, but a product for this skin needs ingredients that directly balance oil production and reduce shine.

### Can this serum clog pores, cause breakouts or purging for oily skin?

This serum is safe for your oily skin and is unlikely to cause irritation or breakouts. However, oily skin needs targeted ingredients like salicylic acid or retinoids to properly clear pores and control excess shine.

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for oily skin

- [Dr.Althea Vitamin C Boosting Serum](https://lovi.care/skincare/ca/p/dr-althea/vitamin-c-boosting-serum/for/oily-skin) — High fit — CA$27.99 at Amazon
- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/ca/p/skin1004/probio-cica-intensive-ampoule/for/oily-skin) — High fit — CA$24.44 at Amazon
- [ANUA PEACH 70% NIACINAMIDE SERUM](https://lovi.care/skincare/ca/p/anua/peach-70-niacinamide-serum/for/oily-skin) — High fit — CA$33.50 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/ca/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — CA$20.96 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/ca/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-skin) — Superior fit — CA$37.60 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/ca/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/oily-skin) — Superior fit — CA$29.98 at Amazon

## Where to buy

No store in Canada has a checked price for this product, so the page shows none.

## Ingredients

Water, Dimethyl Isosorbide, Glycerin, Olive Glycereth-8 Esters Oil, Niacinamide, Hydroxyethyl Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Coconut Alkanes, Malassezin, Rhododendron Ferrugineum Extract, Sodium Hyaluronate, Bisabolol, Carnosine, Tocopherol, Tetrasodium Glutamate Diacetate, Silica, Coco-Caprylate Caprate, Chlorphenesin, Sodium Phytate, Pentylene Glycol, Caprylyl Glycol, Citric Acid, Sodium Hydroxide, Disodium Phosphate, Sodium Chloride, Phenoxyethanol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/mother-science/molecular-hero-serum/for/oily-skin
- United Kingdom: https://lovi.care/skincare/uk/p/mother-science/molecular-hero-serum/for/oily-skin
- Ireland: https://lovi.care/skincare/ie/p/mother-science/molecular-hero-serum/for/oily-skin
- Germany: https://lovi.care/skincare/de/p/mother-science/molecular-hero-serum/for/oily-skin
- France: https://lovi.care/skincare/fr/p/mother-science/molecular-hero-serum/for/oily-skin
- Italy: https://lovi.care/skincare/it/p/mother-science/molecular-hero-serum/for/oily-skin
- Netherlands: https://lovi.care/skincare/nl/p/mother-science/molecular-hero-serum/for/oily-skin
- Spain: https://lovi.care/skincare/es/p/mother-science/molecular-hero-serum/for/oily-skin
- Canada: https://lovi.care/skincare/ca/p/mother-science/molecular-hero-serum/for/oily-skin (this page)
- Australia: https://lovi.care/skincare/au/p/mother-science/molecular-hero-serum/for/oily-skin
- Singapore: https://lovi.care/skincare/sg/p/mother-science/molecular-hero-serum/for/oily-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/mother-science/molecular-hero-serum/for/oily-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/mother-science/molecular-hero-serum/for/oily-skin