# Missha Time Revolution The First Treatment Essence RX for combination skin

**Lovi Fit: High fit for combination skin.**
Combination Skin Fit: High · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/ca/p/missha/time-revolution-the-first-treatment-essence-rx/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Brand: [Missha](https://lovi.care/skincare/ca/brands/missha)
Category: [Serums and treatments](https://lovi.care/skincare/ca/best/serums)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for combination skin; a few serums fit it even better.

## Why this fit

- Offers excellent skin treatment for your combination skin, as Saccharomyces Ferment Filtrate and Bifida Lysate Ferment enhance barrier resilience and smooth texture, while niacinamide and lactic acid help manage oil and gently exfoliate.
- The formula is highly suitable for your combination skin, providing good barrier repair and humectant action.
- The safety profile is excellent, with no risks of irritation due to the absence of harsh ingredients and the presence of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ca/p/missha/time-revolution-the-first-treatment-essence-rx/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/ca/p/missha/time-revolution-the-first-treatment-essence-rx/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/ca/p/missha/time-revolution-the-first-treatment-essence-rx/for/combination-skin): High (this page)
- [Sensitive skin](https://lovi.care/skincare/ca/p/missha/time-revolution-the-first-treatment-essence-rx/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/ca/p/missha/time-revolution-the-first-treatment-essence-rx/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/ca/p/missha/time-revolution-the-first-treatment-essence-rx/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/ca/p/missha/time-revolution-the-first-treatment-essence-rx/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/ca/p/missha/time-revolution-the-first-treatment-essence-rx/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/ca/p/missha/time-revolution-the-first-treatment-essence-rx/for/oily-acne-prone-skin): High

## Key ingredients

Saccharomyces Ferment Filtrate, Bifida Lysate Ferment, Niacinamide, Hordeum Vulgare Extract, Pro Ferment

## What the research says

- Topical application of Bifida Ferment Lysate strengthens the skin barrier function by upregulating barrier and antimicrobial peptide genes, exhibiting strong antioxidant properties, and decreasing inflammatory cytokine secretion in vitro. ([Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37218728/))
- Application of Galactomyces ferment filtrate skin care formula significantly reduced the net values and daily fluctuation of facial pore area, roughness, and redness in young Japanese women. ([Journal of Clinical Medicine, 2021](https://pubmed.ncbi.nlm.nih.gov/34198790/))
- Daily application of Galactomyces ferment filtrate-containing skin products for 12 months significantly and cumulatively reversed 11-year facial skin aging parameters of wrinkles, hyperpigmented spots, and roughness, and increased skin hydration in 86 female volunteers. ([Journal of Clinical Medicine, 2023](https://pubmed.ncbi.nlm.nih.gov/36769815/))
- Topical treatment of nicotinamide, alone or in combination with other active ingredients, reduces the progression of skin aging and hyperpigmentation in clinical trials while being well tolerated. ([Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/))
- Topical moisturizers improved skin barrier function and surface moisture, while a postbiotic moisturizer with yeast extract uniquely supported microbiome balance and modulated biomarkers of skin barrier, structure, and inflammation in participants and ex vivo explants exposed to environmental aggressors. ([Journal of Clinical Medicine, 2023](https://pubmed.ncbi.nlm.nih.gov/37763018/))
- A maintenance therapy with a cosmeceutical formulation containing hydroxyphenoxy propionic acid, ellagic acid, yeast extract, and salicylic acid over 20 weeks significantly improved even skin tone, spot intensity, spot size, and overall hyperpigmentation in 33 healthy subjects with moderate facial dyspigmentation. ([Journal of Drugs in Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25844613/))
- A methanol yeast extract increases proliferation and migration while decreasing entrance into senescence and apoptosis phases in 3T3 fibroblast cells. ([Journal of Cosmetic Science, 2014](https://pubmed.ncbi.nlm.nih.gov/25898765/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))

## What reviewers say

Based on a very large amount of data, users consistently praise this essence for its ability to deeply hydrate and brighten dull skin, often citing it as a cost-effective alternative to luxury products. While it effectively smooths texture and strengthens the moisture barrier for most, a minority of users with fungal acne-prone skin report breakouts due to the fermented ingredients.

- Liked: Brightening Glow (often mentioned)
- Liked: Deep Hydration (often mentioned)
- Liked: Fast Absorption (often mentioned)
- Liked: Texture Refinement (sometimes noted)
- Liked: Value for Money (sometimes noted)
- Disliked: Lack of Results (sometimes noted)
- Disliked: Acne Breakouts (rarely noted)
- Disliked: Sticky Residue (rarely noted)
- Disliked: Unpleasant Scent (rarely noted)

## How to apply

- Use your serum as part of your PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
- Apply the serum after cleansing and toner, and right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏳for it to soak in.
- Apply the serum on clean and dry skin since your skin is not sensitive.
- Always do a patch test before using the serum for the first time, and avoid the eye area .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Missha Time Revolution Essence RX a great fit for combination skin?

Missha Time Revolution Essence RX is a great fit for your combination skin because Saccharomyces Ferment Filtrate and Bifida Lysate Ferment strengthen your skin barrier and smooth your texture. Niacinamide and lactic acid also help manage oil and gently exfoliate your skin without causing irritation.
Sources: [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37218728/), [Journal of Clinical Medicine, 2021](https://pubmed.ncbi.nlm.nih.gov/34198790/)

### Which ingredients make this treatment a good fit for combination skin?

Saccharomyces Ferment Filtrate and Bifida Lysate Ferment make this a great fit because they strengthen your skin barrier and smooth your texture. Niacinamide and lactic acid also help manage oil and gently exfoliate your skin.
Sources: [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37218728/)

### What does Saccharomyces Ferment Filtrate do for combination skin?

Saccharomyces Ferment Filtrate helps balance combination skin by boosting moisture and smoothing out rough spots. Ferment ingredients in general help calm redness and support the skin barrier, keeping both dry and oily areas comfortable.

### What does Bifida Ferment Lysate do for combination skin?

Bifida Ferment Lysate helps strengthen the skin barrier and calm irritation, making it a good fit for combination skin that is prone to sensitivity. This ingredient works by supporting the skin defenses, keeping moisture locked in, and helping to reduce redness.
Sources: [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37218728/), [Experimental Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/19624730/)

### Where does this treatment go in a skincare routine for combination skin?

This treatment goes in the evening routine after cleansing and before moisturizing. Putting it in the evening helps keep the routine simple and adds extra safety around sun exposure.

### Can I use this treatment with retinol, and in what order?

You can use this treatment with retinol by applying the treatment first and following with your retinol. Because this formula is very gentle and free of harsh ingredients, it is unlikely to cause irritation when layered with your retinoid.

### How often should I use this treatment?

This treatment fits into your evening routine once a week to start, as Lovi routines suggest for exfoliating steps. People who tolerate it well and see good results can carefully use it more often.

### Can this treatment clog pores, cause breakouts or purging for combination skin?

This treatment is unlikely to clog pores or cause breakouts for combination skin because its safety profile is excellent and harsh ingredients are absent. Reviewers rarely report acne breakouts, and ferment ingredients like Saccharomyces Ferment Filtrate and Bifida Lysate Ferment help maintain a clear, balanced complexion.
Sources: [Journal of Clinical Medicine, 2021](https://pubmed.ncbi.nlm.nih.gov/34198790/), [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37218728/)

### Is this treatment fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for combination skin

- [COSRX Galactomyces 95 Tone Balancing Essence](https://lovi.care/skincare/ca/p/cosrx/galactomyces-95-tone-balancing-essence/for/combination-skin) — Superior fit — CA$24.49 at Amazon
- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/ca/p/skin1004/probio-cica-intensive-ampoule/for/combination-skin) — High fit — CA$24.44 at Amazon
- [Dr. Ceuracle Tea Tree Purifine 95 Essence](https://lovi.care/skincare/ca/p/dr-ceuracle/tea-tree-purifine-95-essence/for/combination-skin) — High fit — CA$48.14 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/ca/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — CA$44.95 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/ca/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — CA$37.60 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/ca/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/combination-skin) — Superior fit — CA$29.98 at Amazon

## Where to buy

- Amazon.ca: CA$42.99 (https://www.amazon.ca/dp/B01FG5VLLU?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Saccharomyces Ferment Filtrate, Bifida Lysate Ferment, Water, Diethoxyethyl Succinate, Niacinamide, Hordeum Vulgare Extract, Cassia Alata Leaf Extract, Glycerin, Dipropylene Glycol, Dimethicone, Polyquaternium-51, 1,2-Hexanediol, Adenosine, Lecithin, Lactic Acid, Acetic Acid, Phenoxyethanol, Potassium Sorbate
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/missha/time-revolution-the-first-treatment-essence-rx/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/missha/time-revolution-the-first-treatment-essence-rx/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/missha/time-revolution-the-first-treatment-essence-rx/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/missha/time-revolution-the-first-treatment-essence-rx/for/combination-skin
- France: https://lovi.care/skincare/fr/p/missha/time-revolution-the-first-treatment-essence-rx/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/missha/time-revolution-the-first-treatment-essence-rx/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/missha/time-revolution-the-first-treatment-essence-rx/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/missha/time-revolution-the-first-treatment-essence-rx/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/missha/time-revolution-the-first-treatment-essence-rx/for/combination-skin (this page)
- Australia: https://lovi.care/skincare/au/p/missha/time-revolution-the-first-treatment-essence-rx/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/missha/time-revolution-the-first-treatment-essence-rx/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/missha/time-revolution-the-first-treatment-essence-rx/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/missha/time-revolution-the-first-treatment-essence-rx/for/combination-skin