Menarini A-Ret Gel for oily acne-prone skin

How to apply

Questions and answers

What the research says

• A galenic compound containing essential oils and tretinoin demonstrated anti-acne efficacy and anti-inflammatory activity, significantly reducing papular erythema and retinoid-induced rashes compared to clindamycin-tretinoin gel in sixty volunteers over 30 days.

  Clinical, Cosmetic and Investigational Dermatology, 2020

• Tretinoin-loaded nano lipid carriers resulted in a significantly higher rate of decrease in acne lesions and greater reduction in porphyrin production compared to conventional tretinoin cream in patients with mild to moderate acne vulgaris.

  Archives of Dermatological Research, 2022

• Butylated hydroxytoluene (BHT) is safe as used in cosmetic formulations at concentrations ranging from 0.0002% to 0.5% due to low dermal penetration and systemic exposure compared to oral administration.

  International Journal of Toxicology, 2002

• Pranoprofen-loaded nanostructured lipid carriers dispersed in Carbomer 940 and Sepigel 305 gels provided sustained drug release and demonstrated anti-inflammatory efficacy in animal models without causing skin irritation or altering biophysical properties in humans.

  Gels, 2023

• Topical tretinoin improves clinical appearance of photoaging in terms of wrinkling, mottled hyperpigmentation, sallowness, and lentigines and is safe and well tolerated.

  International Journal of Women's Dermatology, 2022

• Topical tretinoin daily application for 10 to 12 months produced an 80 percent increase in collagen I formation in photodamaged human skin compared with a 14 percent decrease with vehicle alone.

  The New England Journal of Medicine, 1993

• Topical tretinoin precursors and tretinoin showed no significant difference in efficacy for moderate to severe facial photodamage in 20 patients, while tretinoin precursors caused erythema six times less frequently.

  JAMA Dermatology, 2022

• Treatment with a combination of propylene glycol, ethanol, water, and shampoo was found effective, easy to use, and cosmetically attractive with no observed side effects in patients with dandruff.

  Cutis, 1988

• A moisturizer containing glycerol and propylene glycol reduced transepidermal water loss, decreased epidermal thickness, increased stratum corneum thickness, and reduced dermal inflammatory infiltrate compared to untreated disrupted skin in six healthy beagle dogs.

  Veterinary Dermatology, 2020

• The use of 70% isopropyl alcohol in conjunction with scrubbing with a bristled brush significantly reduced positive bacterial cultures at the nail fold compared to povidone-iodine with soft sponges in volunteers.

  The Journal of Bone and Joint Surgery. American Volume, 2005

• Friction with 70% ethyl or isopropyl alcohol immediately eliminates the heart-shaped pigmented lesion characteristic of terra firma-forme dermatosis in a 14-year-old boy.

  Cureus, 2024

• Rubbing 70% isopropyl alcohol wipes cleared persistent reticulated brown patches in five patients with terra firma-forme dermatosis.

  Skinmed, 2016

• Topical chloramphenicol-betamethasone combined with sodium hyaluronate/trehalose/carbomer gel compared to chloramphenicol-betamethasone alone reduced most subjective symptoms at 1 week but increased blurred vision at 4 weeks following strabismus surgery in 31 patients, with no significant differences in conjunctival inflammation between treatments.

  Journal of Ocular Pharmacology and Therapeutics, 2019

• Incorporating nanoemulsions into hydrogels with increasing Carbopol 934 proportions from 1% to 3% progressively decreased the percutaneous flux rates of terbinafine and citral, increased drug accumulation in the stratum corneum while decreasing it in the epidermis/dermis compared to nanoemulsions alone, and shifted delivery routes from skin appendages to intercellular paths.

  International Journal of Nanomedicine, 2016

• Topical liquiritin carbomer gel treatment restored skin barrier function, increased barrier proteins and antioxidant enzymes, and decreased inflammatory cytokines and oxidative stress in a mouse model of glucocorticoid-induced skin inflammation.

  Pharmaceutics, 2024

Ingredients

Tretinoin, Propylene Glycol, Isopropanol, Carbomer, Triethanolamine, Butylated Hydroxytoluene, Methyl Hydroxybenzoate, Propyl Hydroxybenzoate

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.