# Medik8 Liquid Peptides for sensitive skin

**Lovi Fit: Average fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/ca/p/medik8/liquid-peptides/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Brand: [Medik8](https://lovi.care/skincare/ca/brands/medik8)
Category: [Serums and treatments](https://lovi.care/skincare/ca/best/serums)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for sensitive skin; other serums fit it better.

## Why this fit

- Suitable for normal skin, this formula contains Glycerin and Hyaluronic Acid to support hydration without causing irritation, aligning with your skin type and sensitivity.
- The presence of Acetyl Hexapeptide-8 and Palmitoyl Tripeptide-1 offers moderate plumping benefits, contributing to skin volume and elasticity.
- The product is safe for your sensitive skin as it lacks harsh or prohibited ingredients, ensuring no risks of irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ca/p/medik8/liquid-peptides/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/ca/p/medik8/liquid-peptides/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/ca/p/medik8/liquid-peptides/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/ca/p/medik8/liquid-peptides/for/sensitive-skin): Average (this page)
- [Acne-prone skin](https://lovi.care/skincare/ca/p/medik8/liquid-peptides/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/ca/p/medik8/liquid-peptides/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/ca/p/medik8/liquid-peptides/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/ca/p/medik8/liquid-peptides/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/ca/p/medik8/liquid-peptides/for/oily-acne-prone-skin): Average

## Key ingredients

Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Chronomodulated daytime application of baicalin and nighttime application of palmitoyl tripeptide-1 synergistically improved skin luminance by 16.29%, nasolabial fold depth by -36.35%, and firmness by 24.35% in 30 female participants. ([Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/))
- A multi-modal methodology combining MALDI-MSI, in vivo RCM, echography, and histology revealed age-related decreases in extracellular matrix and epidermal-dermal junction proteins and undulation depth, while a blend of palmitoyl oligopeptide and palmitoyl tetrapeptide-7 improved subepidermal low-echogenic band thickness, density, and extracellular matrix structure compared to placebo. ([Journal of Cosmetic Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25817264/))
- Treatment with cross-linked hyaluronic acid-based microneedle patches combined with acetyl hexapeptide-8 or epidermal growth factor significantly improved wrinkles and skin hydration compared to the patch alone in Korean females over 29 days. ([Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/))
- Argireline treatment twice daily for 4 weeks produced a significant anti-wrinkle effect with 48.9% total efficacy and decreased skin roughness in Chinese subjects compared with 0% efficacy and no decrease in roughness in the placebo group. ([American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/))
- Acetyl hexapeptide-3 and tripeptide-10 citrulline demonstrated antiwrinkle efficacy and decreased transepidermal water loss in twenty-four healthy volunteers compared to control groups, though synergistic effects between the two peptides remained unclear. ([Journal of Cosmetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28150423/))
- Palmitoyl tetrapeptide-7, acetyl hexapeptide-8, palmitoyl tripeptide-1, and palmitoyl tetrapeptide-10 significantly increased type III collagen levels in human dermal fibroblasts following UV exposure, with their combination demonstrating a greater effect in vitro and enhancing type I, III, and IV collagen levels in ex vivo skin tissues compared to individual components. ([International Journal of Cosmetic Science, 2026](https://pubmed.ncbi.nlm.nih.gov/42683869/))

## What reviewers say

Users consistently praise this serum as a "Botox in a bottle" alternative that delivers immediate hydration and visible plumping, particularly for fine lines on the forehead and around the eyes. It is widely celebrated for its ability to smooth skin texture and restore bounce to dry or mature skin without causing irritation, making it a staple for those targeting early to advanced signs of aging.

- Liked: Deeply hydrating (mostly mentioned)
- Liked: Elegant, lightweight texture (often mentioned)
- Liked: Visibly plumps and smooths (often mentioned)
- Disliked: High price point (often mentioned)
- Liked: Gentle and non-irritating (sometimes noted)
- Disliked: Packaging fragility (sometimes noted)
- Disliked: Results require patience (rarely noted)
- Disliked: Slight tackiness (rarely noted)

## How to apply

- Use your serum in the PM routine, starting 3 times a week before building up to daily use if your skin is happy.
- Apply the serum after cleansing and toning, but before putting on your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏱ for it to soak in.
- Since your skin is sensitive and easily irritated, apply the serum on completely dry skin to help keep it calm.
- Always do a patch test before your first use and avoid getting the serum too close to your eyes .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Medik8 Liquid Peptides work for sensitive skin?

Medik8 Liquid Peptides works for sensitive skin, though other treatments fit it better. It contains glycerin and hyaluronic acid to help keep skin hydrated, along with peptides that may give moderate plumping benefits. Treatments that fit sensitive skin better need soothing ingredients that calm redness and irritation while keeping the skin barrier healthy.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this serum a good fit for sensitive skin?

Glycerin and Hyaluronic Acid help support hydration without causing irritation, making this serum a workable fit for sensitive skin. To fit sensitive skin even better, a treatment of this type needs effective ingredients that soothe redness and irritation while remaining highly compatible.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Argireline do for sensitive skin?

Argireline is unlikely to cause irritation and is sometimes found in products designed to calm reactive skin. Studies show it helps smooth the look of wrinkles and decrease skin roughness when used consistently.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/), [Pharmaceuticals, 2021](https://pubmed.ncbi.nlm.nih.gov/34451799/)

### What does Palmitoyl Tripeptide-1 do for sensitive skin?

Palmitoyl tripeptide-1 helps smooth fine lines and improves firmness in sensitive skin. It works by supporting collagen levels to keep skin looking youthful and resilient.
Sources: [Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/), [International Journal of Cosmetic Science, 2026](https://pubmed.ncbi.nlm.nih.gov/42683869/)

### Where does it go in a skincare routine for sensitive skin?

This treatment goes in the evening routine for sensitive skin. It is safe for this skin type and is unlikely to cause irritation, though other products fit sensitive skin better by featuring extra calming and barrier-repairing ingredients.

### Can I use this serum with retinol, and in what order?

Yes, you can use this treatment with retinol by applying your retinol product first and following with this serum. This approach helps keep your sensitive skin hydrated with glycerin and hyaluronic acid while minimizing any risk of irritation. For this skin type, a product of this type needs calming agents and gentle hydrators to support the skin barrier effectively.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### How often should I use it?

Use this treatment in the evening as part of your routine to keep things simple and safe around sun exposure. A product of this type needs soothing ingredients like glycerin and hyaluronic acid to support hydration without causing irritation for your sensitive skin.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can this serum clog pores, cause breakouts or purging for sensitive skin?

This serum is unlikely to clog pores or cause breakouts for sensitive skin because it lacks harsh ingredients and relies on hydrating components like glycerin and hyaluronic acid. Products of this type for sensitive skin need gentle hydrators and soothing agents that support moisture without causing irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Is it fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for sensitive skin

- [Clarins Double Serum](https://lovi.care/skincare/ca/p/clarins/double-serum/for/sensitive-skin) — High fit — CA$113.00 at Amazon
- [COSRX The Vitamin C 23 Serum](https://lovi.care/skincare/ca/p/cosrx/the-vitamin-c-23-serum/for/sensitive-skin) — High fit — CA$33.98 at Amazon
- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/ca/p/skin1004/probio-cica-intensive-ampoule/for/sensitive-skin) — High fit — CA$24.44 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/ca/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — CA$44.95 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/ca/p/clarins/soothing-toning-lotion/for/sensitive-skin) — Superior fit — CA$49.00 at Amazon
- Moisturizer with Sun Protection: [Torriden DIVE-IN Mild Sunscreen](https://lovi.care/skincare/ca/p/torriden/dive-in-mild-sunscreen/for/sensitive-skin) — Superior fit — CA$27.34 at Amazon

## Where to buy

- Amazon.ca: CA$133.00 (https://www.amazon.ca/dp/B0DT1LYVZ6?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- Sephora: CA$133.00 (https://www.sephora.com/ca/en/product/liquid-peptides-advanced-mp-serum-P525991?skuId=3011376)
Prices checked 16 Oct – 6 Nov 2026.

## Ingredients

Water, Glycerin, Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Carbomer, Phenoxyethanol, Ethylhexylglycerin, Hyaluronic Acid, Lecithin, Caprylyl Glycol, Disodium Edta, Citric Acid
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/medik8/liquid-peptides/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/medik8/liquid-peptides/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/medik8/liquid-peptides/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/medik8/liquid-peptides/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/medik8/liquid-peptides/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/medik8/liquid-peptides/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/medik8/liquid-peptides/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/medik8/liquid-peptides/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/medik8/liquid-peptides/for/sensitive-skin (this page)
- Australia: https://lovi.care/skincare/au/p/medik8/liquid-peptides/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/medik8/liquid-peptides/for/sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/medik8/liquid-peptides/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/medik8/liquid-peptides/for/sensitive-skin