# medicube Exosome Cica Calming Toner for oily skin

**Lovi Fit: Average fit for oily skin.**
Oily Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/ca/p/medicube/exosome-cica-calming-toner/for/oily-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Brand: [medicube](https://lovi.care/skincare/ca/brands/medicube)
Category: [Toners](https://lovi.care/skincare/ca/best/toners)

This fit is calculated for the concerns frequently associated with oily skin: shine, enlarged pores, blackheads, and blemishes. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for oily skin; other toners fit it better.

## Why this fit

- Offers moderate soothing and hydration for your oily skin, as Centella Asiatica Extract and Glycerin provide calming and moisturizing benefits, though they do not specifically target oily shine.
- The anti-inflammatory and seboregulating actions of Centella Asiatica Extract and Heart Leaf Extract make it highly suitable for your oily skin type.
- The product is safe for your skin, with no risks of irritation due to the absence of harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ca/p/medicube/exosome-cica-calming-toner/for/oily-skin): Average (this page)
- [Dry skin](https://lovi.care/skincare/ca/p/medicube/exosome-cica-calming-toner/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/ca/p/medicube/exosome-cica-calming-toner/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/ca/p/medicube/exosome-cica-calming-toner/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/ca/p/medicube/exosome-cica-calming-toner/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/ca/p/medicube/exosome-cica-calming-toner/for/dark-spots): Low
- [Mature skin](https://lovi.care/skincare/ca/p/medicube/exosome-cica-calming-toner/for/mature-skin): Low
- [Dry sensitive skin](https://lovi.care/skincare/ca/p/medicube/exosome-cica-calming-toner/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/ca/p/medicube/exosome-cica-calming-toner/for/oily-acne-prone-skin): High

## Key ingredients

Centella Asiatica Extract, Exosome, Heart Leaf Extract

## What the research says

- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- Houttuynia cordata extract containing hyperoside and quercitrin protected human HaCaT keratinocytes from UVB-induced cell damage, apoptosis, oxidative stress, and inflammation by modulating MAPKs and Akt signaling pathways. ([Antioxidants, 2022](https://pubmed.ncbi.nlm.nih.gov/35204104/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Adjuvant application of human adipose tissue stem cell-derived exosomes gel following fractional CO2 laser significantly improved the reduction of acne scars (32.5% vs 19.9%, p < 0.01) and reduced erythema and downtime in 25 patients compared to the control gel. ([Acta Dermato-venereologica, 2020](https://pubmed.ncbi.nlm.nih.gov/33073298/))
- Topical mesenchymal stem cell-derived exosomes reduced Ocular Surface Disease Index scores, increased tear secretion, lowered fluorescein scores, prolonged tear-film break-up time, increased Epidermal Growth Factor and thrombospondin-1, and decreased interleukin-6 and Matrix metalloproteinase-9 in patients with Sjögren's syndrome-related dry eye compared to phosphate buffered saline control. ([BMC Ophthalmology, 2025](https://pubmed.ncbi.nlm.nih.gov/40394561/))
- Topical human platelet extract exosome serum improved skin health scores and reduced redness, wrinkles, and melanin production while enhancing luminosity and color evenness at 6 weeks. ([Aesthetic Surgery Journal, 2022](https://pubmed.ncbi.nlm.nih.gov/35689936/))
- Quercetin phospholipids 1% cream significantly reduced UV-, histamine-, and chemical-induced skin erythema (-10.05%) and mean wheal diameter in 30 healthy human volunteers, showing comparable efficacy to 1% dexchlorpheniramine cream. ([Clinical, Cosmetic and Investigational Dermatology, 2016](https://pubmed.ncbi.nlm.nih.gov/27013898/))
- Quercetin-loaded niosomes formulated with Span60-RH40 at a 9:11 mass ratio improved quercetin solubility, photostability, sustained release, and transdermal penetration, yielding a skin retention 2.95 times higher than quercetin solution. ([Molecules, 2019](https://pubmed.ncbi.nlm.nih.gov/31238562/))
- Optimized rutin-loaded glycerosomes formulated into a nanosunscreen gel demonstrated sustained drug release, greater skin permeation, good antioxidant activity, and better epidermal retention compared to the dermis, indicating high safety, stability, and sun protection factor values for topical administration. ([Gels, 2023](https://pubmed.ncbi.nlm.nih.gov/37754433/))

## What reviewers say

This toner is highly praised for its lightweight, watery texture that absorbs quickly without stickiness, making it suitable for oily and acne-prone skin. It is very effective at reducing redness and soothing irritation, with many users reporting improved skin balance. Some users noted concerns about the scent, price, and potential for fungal acne, though these were less common observations.

- Liked: Calms redness (mostly mentioned)
- Liked: Lightweight absorption (mostly mentioned)
- Liked: Deeply hydrating (often mentioned)
- Liked: Improves acne (sometimes noted)
- Disliked: Not fungal acne safe (rarely noted)
- Disliked: Price point (rarely noted)
- Disliked: Scent preferences (rarely noted)
- Disliked: Unclear long-term benefits (rarely noted)

## How to apply

- Could be used as part of your AM or PM routine. Start using your soothing toner 3 times a week and work up to daily use if your skin likes it.
- Apply your soothing toner after cleansing and before your moisturizer or SPF.
- Gently press 2-3 drops of the soothing toner into your skin with your hands. Let it absorb for a minute before moving on ⏱ to the next step.
- For the best results , apply your soothing toner to slightly damp skin to help it sink in better.
- Avoid the sensitive eye area and do a quick patch test before using the soothing toner for the very first time.
- Video: https://storage.pora.ai/25abe7eb181ba53153fd15de2058c2a9.mp4

## Questions and answers

### How well does medicube Exosome Cica Calming Toner work for oily skin?

This toner works moderately well for oily skin by offering calm and hydration through Centella Asiatica Extract and glycerin, though it does not specifically target oily shine. A soothing toner for oily skin needs ingredients that control excess oil and minimize shine while keeping the skin calm.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Which ingredients make this toner a good fit for oily skin?

Centella Asiatica Extract and Heart Leaf Extract make this toner a good fit for oily skin because they help calm irritation and regulate oil. To work best for oily skin, a product of this type needs ingredients that effectively control excess oil and minimize shine while keeping skin calm and hydrated.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### What does Centella Asiatica Extract do for oily skin?

Centella Asiatica Extract helps calm redness and keeps oily skin feeling balanced by soothing irritation and supporting moisture levels. It is unlikely to feel heavy, and products of this type for oily skin need ingredients that control excess shine while maintaining hydration.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### What do Exosomes do for oily skin?

Exosomes help balance oily skin by regulating sebum production and supporting cell activity. Because oily skin needs ingredients that control excess oil without causing irritation, this type of product should include soothing and balancing components.
Sources: [Biochimie, 2026](https://pubmed.ncbi.nlm.nih.gov/42833608/), [Scientific Reports, 2023](https://pubmed.ncbi.nlm.nih.gov/37749255/)

### Where does this toner go in a skincare routine for oily skin?

This soothing toner goes in the morning step after cleansing and before moisturizing. Oily skin also benefits from ingredients that help control shine and reduce excess oil.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use this toner with retinol, and in what order?

You can use this toner with retinol by applying the toner first to calm your skin, followed by your retinol treatment. This toner is very safe and unlikely to cause irritation on oily skin, but an oily skin routine also needs ingredients that specifically target excess shine and oil production.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### How often should I use this toner?

You can use this toner daily in your morning routine, as it offers moderate soothing and hydration without heavy oils. To truly fit oily skin and control shine, a product of this type needs dedicated oil-balancing ingredients.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can this toner clog pores, cause breakouts or purging for oily skin?

This toner is unlikely to clog pores or cause breakouts for your oily skin because it has a safe formula without harsh ingredients, though a product for this skin needs oil-controlling ingredients to properly target shine.

## Alternatives for oily skin

- [Fundamental Soothing Toner](https://lovi.care/skincare/ca/p/fundamental/soothing-toner/for/oily-skin) — High fit — CA$29.99 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/ca/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — CA$20.96 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/ca/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/oily-skin) — Superior fit — CA$29.98 at Amazon
- SPF: [La Roche-Posay Anthelios Clear Skin Dry Touch Sunscreen SPF 60](https://lovi.care/skincare/ca/p/la-roche-posay/anthelios-clear-skin-dry-touch-sunscreen-spf-60/for/oily-skin) — Superior fit — CA$35.95 at Amazon

## Where to buy

No store in Canada has a checked price for this product, so the page shows none.

## Ingredients

Centella Asiatica Extract, Exosome, Heart Leaf Extract, Extract Tree, Glycerin, Butylene Glycol, Water
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/medicube/exosome-cica-calming-toner/for/oily-skin
- United Kingdom: https://lovi.care/skincare/uk/p/medicube/exosome-cica-calming-toner/for/oily-skin
- Ireland: https://lovi.care/skincare/ie/p/medicube/exosome-cica-calming-toner/for/oily-skin
- Germany: https://lovi.care/skincare/de/p/medicube/exosome-cica-calming-toner/for/oily-skin
- France: https://lovi.care/skincare/fr/p/medicube/exosome-cica-calming-toner/for/oily-skin
- Italy: https://lovi.care/skincare/it/p/medicube/exosome-cica-calming-toner/for/oily-skin
- Netherlands: https://lovi.care/skincare/nl/p/medicube/exosome-cica-calming-toner/for/oily-skin
- Spain: https://lovi.care/skincare/es/p/medicube/exosome-cica-calming-toner/for/oily-skin
- Canada: https://lovi.care/skincare/ca/p/medicube/exosome-cica-calming-toner/for/oily-skin (this page)
- Australia: https://lovi.care/skincare/au/p/medicube/exosome-cica-calming-toner/for/oily-skin
- Singapore: https://lovi.care/skincare/sg/p/medicube/exosome-cica-calming-toner/for/oily-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/medicube/exosome-cica-calming-toner/for/oily-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/medicube/exosome-cica-calming-toner/for/oily-skin