# Medicube Deep Peptide Radiance Mask for dry sensitive skin

**Lovi Fit: High fit for dry sensitive skin.**
Dry Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/ca/p/medicube/deep-peptide-radiance-mask/for/dry-sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Brand: [Medicube](https://lovi.care/skincare/ca/brands/medicube)
Category: [Face masks](https://lovi.care/skincare/ca/best/face-masks)

This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for dry sensitive skin; a few nourishing masks fit it even better.

## Why this fit

- Highly suitable for your dry and sensitive skin, this product offers excellent nourishing effects with peptides like Acetyl Hexapeptide-1 and high concentrations of hydrating Glycerin and Hydrolyzed Hyaluronic Acid to replenish moisture and support your skin barrier.
- The inclusion of Panthenol and Ceramide NP further aids in soothing and repairing, addressing your dry or flaky skin concerns effectively.
- The safety profile is excellent, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ca/p/medicube/deep-peptide-radiance-mask/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/ca/p/medicube/deep-peptide-radiance-mask/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/ca/p/medicube/deep-peptide-radiance-mask/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/ca/p/medicube/deep-peptide-radiance-mask/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/ca/p/medicube/deep-peptide-radiance-mask/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/ca/p/medicube/deep-peptide-radiance-mask/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/ca/p/medicube/deep-peptide-radiance-mask/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/ca/p/medicube/deep-peptide-radiance-mask/for/dry-sensitive-skin): High (this page)
- [Oily acne-prone skin](https://lovi.care/skincare/ca/p/medicube/deep-peptide-radiance-mask/for/oily-acne-prone-skin): Superior

## Key ingredients

Peptide Complex, Niacinamide, Centella Asiatica Leaf Extract, Hydrolyzed Hyaluronic Acid, Ceramide Np

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))

## What reviewers say

Based on limited data, users love this mask for its intense hydration and ability to provide an instant glow, making it ideal for dry, dull, or sensitive skin. The peptide-rich essence is praised for plumping fine lines and soothing irritation without a sticky feel. Some users find the price high for frequent use and note the sheet size can be slightly small.

- Liked: Intense hydration (mostly mentioned)
- Liked: Instant radiance (often mentioned)
- Liked: Non-sticky finish (sometimes noted)
- Liked: Soothing and plumping (sometimes noted)
- Disliked: High price point (sometimes noted)
- Disliked: Handling difficulty (rarely noted)
- Disliked: Sheet fit issues (rarely noted)

## How to apply

- Could be used as part of your AM or PM routine. Start using your sheet mask 3 times a week and increase to daily use if your dry skin tolerates it.
- Apply the sheet mask right after cleansing and toning, but always before your rich moisturizer .
- Unfold the sheet mask gently and smooth it evenly over your face, avoiding any harsh pulling or rubbing.
- Place the sheet mask onto clean, slightly damp skin to help lock in extra moisture for flaky areas.
- Avoid the sensitive eye area and do a quick patch test before your very first use.
- Video: https://storage.pora.ai/cf9cbc1593b43309df7ca9cfe4fbbdae.mp4

## Questions and answers

### What makes medicube Deep Peptide Radiance Mask a great fit for dry sensitive skin?

This mask is a great fit for your dry sensitive skin because it uses peptides, glycerin, and hydrolyzed hyaluronic acid to bring back deep moisture and support your skin barrier. Panthenol and ceramide NP help calm and repair flaky areas safely without causing irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this mask a good fit for dry sensitive skin?

This mask is a great fit for your dry sensitive skin because it contains nourishing peptides, hydrating glycerin and hydrolyzed hyaluronic acid, plus panthenol and ceramide NP to soothe and repair your skin barrier. These ingredients help boost moisture and are very gentle, making them safe and unlikely to cause irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Peptide Complex do for dry sensitive skin?

Peptide Complex helps soothe dry sensitive skin by reducing fine lines, improving smoothness, and calming irritation while supporting the skin barrier. It is unlikely to cause irritation and works well to keep skin soft and comfortable.
Sources: [International Journal of Cosmetic Science, 2005](https://pubmed.ncbi.nlm.nih.gov/18492182/), [International Journal of Cosmetic Science, 2009](https://pubmed.ncbi.nlm.nih.gov/19496838/)

### What does Niacinamide do for dry sensitive skin?

Niacinamide helps dry sensitive skin by calming irritation and keeping moisture locked in so your face feels soft and smooth. It works to build up your skin barrier and calm redness while being very gentle and unlikely to cause irritation.
Sources: [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/), [International Journal of Pharmaceutics, 2013](https://pubmed.ncbi.nlm.nih.gov/23220080/)

### Where does it go in a skincare routine for dry sensitive skin?

This nourishing mask is used weekly as part of your evening routine after makeup removal and cleansing. The formula helps replenish moisture and calm dry or flaky skin with a safe blend of peptides, glycerin, hyaluronic acid, and panthenol.
Sources: [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use this mask with retinol, and in what order?

You can use this nourishing mask with retinol by applying it during your weekly routine before your treatment step, as it helps replenish moisture and soothe your skin barrier. Its gentle, soothing formula is unlikely to cause irritation when combined with active treatments.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### How often should I use it?

You can use this nourishing mask once a week as part of your routine. This frequency helps maintain hydration and supports your skin barrier without causing irritation.
Sources: [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can this mask clog pores, cause breakouts or purging for dry sensitive skin?

This mask is unlikely to clog pores or cause breakouts for dry sensitive skin because it is formulated without harsh or heavy ingredients that typically trigger irritation or congestion. Its nourishing blend of hydrating and soothing ingredients supports your skin barrier safely without unwanted reactions.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Is it fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Behenyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for dry sensitive skin

- [Anua Heartleaf 77% Soothing Sheet Mask](https://lovi.care/skincare/ca/p/anua/heartleaf-77-soothing-sheet-mask/for/dry-sensitive-skin) — High fit — CA$10.00 at Amazon
- [Mediheal Watermide Essential Mask](https://lovi.care/skincare/ca/p/mediheal/watermide-essential-mask/for/dry-sensitive-skin) — High fit — CA$29.00 at Amazon
- [Medicube Collagen Night Wrapping Mask](https://lovi.care/skincare/ca/p/medicube/collagen-night-wrapping-mask/for/dry-sensitive-skin) — High fit — CA$24.00 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/ca/p/cerave/hydrating-facial-cleanser/for/dry-sensitive-skin) — Superior fit — CA$20.19 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/ca/p/clarins/soothing-toning-lotion/for/dry-sensitive-skin) — Superior fit — CA$49.00 at Amazon
- Moisturizer with Sun Protection: [d'Alba UVessence Mild Waterfull Sun Cream SPF 50](https://lovi.care/skincare/ca/p/d-alba/uvessence-mild-waterfull-sun-cream-spf-50/for/dry-sensitive-skin) — Superior fit — CA$38.00 at Amazon

## Where to buy

- Amazon.ca: CA$18.35 (https://www.amazon.ca/dp/B09BC8LNJJ?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Water, Dipropylene Glycol, Glycerin, Butylene Glycol, Niacinamide, 1,2-Hexanediol, Cetyl Ethylhexanoate, Panthenol, Allantoin, Xylitol, Centella Asiatica Leaf Extract, Lactobacillus Lysate Ferment, Lactococcus Lysate Ferment, Bifida Lysate Ferment, Caprylyl Glycol, Sorbitan Laurate, Hydrogenated Lecithin, Hydrolyzed Hyaluronic Acid, Tocopherol, Asiaticoside, Madecassic Acid, Asiatic Acid, Acetyl Dipeptide-1, Cetyl Ester, Acetyl Hexapeptide-1, Palmitoyl Tripeptide-5, Beta-Glucan, Ceramide Np, Acetyl Octapeptide-3, Hydrogenated Oil, Behenyl Alcohol, Polyglyceryl-3 Methylglucose Distearate, Arginine, Carbomer, Adenosine, Hydroxyethylcellulose, Ethylhexylglycerin, Disodium Edta
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/medicube/deep-peptide-radiance-mask/for/dry-sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/medicube/deep-peptide-radiance-mask/for/dry-sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/medicube/deep-peptide-radiance-mask/for/dry-sensitive-skin
- Germany: https://lovi.care/skincare/de/p/medicube/deep-peptide-radiance-mask/for/dry-sensitive-skin
- France: https://lovi.care/skincare/fr/p/medicube/deep-peptide-radiance-mask/for/dry-sensitive-skin
- Italy: https://lovi.care/skincare/it/p/medicube/deep-peptide-radiance-mask/for/dry-sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/medicube/deep-peptide-radiance-mask/for/dry-sensitive-skin
- Spain: https://lovi.care/skincare/es/p/medicube/deep-peptide-radiance-mask/for/dry-sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/medicube/deep-peptide-radiance-mask/for/dry-sensitive-skin (this page)
- Australia: https://lovi.care/skincare/au/p/medicube/deep-peptide-radiance-mask/for/dry-sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/medicube/deep-peptide-radiance-mask/for/dry-sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/medicube/deep-peptide-radiance-mask/for/dry-sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/medicube/deep-peptide-radiance-mask/for/dry-sensitive-skin