# Medicube Collagen Glow Bubble Serum for combination skin

**Lovi Fit: Average fit for combination skin.**
Combination Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/ca/p/medicube/collagen-glow-bubble-serum/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Brand: [Medicube](https://lovi.care/skincare/ca/brands/medicube)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/ca/best/moisturizers)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for combination skin; other moisturizers fit it better.

## Why this fit

- Offers moderate moisturizing for your combination skin due to glycerin and sodium hyaluronate, which hydrate and plump the skin without causing irritation. Hydroxyethyl urea further enhances humectant action, providing general hydration benefits for oily shine.
- The formula is safe for your combination skin as it lacks harsh ingredients and is free from irritants.
- While it provides good hydration, it lacks sufficient ingredients for potent seboregulation, which would better address your oily shine.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ca/p/medicube/collagen-glow-bubble-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/ca/p/medicube/collagen-glow-bubble-serum/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/ca/p/medicube/collagen-glow-bubble-serum/for/combination-skin): Average (this page)
- [Sensitive skin](https://lovi.care/skincare/ca/p/medicube/collagen-glow-bubble-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/ca/p/medicube/collagen-glow-bubble-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/ca/p/medicube/collagen-glow-bubble-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/ca/p/medicube/collagen-glow-bubble-serum/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/ca/p/medicube/collagen-glow-bubble-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/ca/p/medicube/collagen-glow-bubble-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Water-Soluble Collagen, Niacinamide, Sodium Hyaluronate, Collagen-11 Complex, Retinal

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical application of TAC/Collagen postbiotics gel improved skin moisture score and inflammation index, and reduced porphyrins and brown spots in 20 volunteers with acne vulgaris. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35818134/))
- Topical collagen tripeptide application improved skin wrinkles, elasticity, and density while reducing advanced glycated end products in 22 Asian women over 4 weeks. ([International Journal of Molecular Sciences, 2022](https://pubmed.ncbi.nlm.nih.gov/35163025/))
- Marine collagen extracted from Greenland halibut skin showed a non-cytotoxic effect on fibroblast cells and provided a slight skin hydration effect when incorporated into cosmetic hydrogel formulations at dosages of 0.1, 0.25, and 0.5% in 23 healthy volunteers. ([Marine Drugs, 2023](https://pubmed.ncbi.nlm.nih.gov/36827098/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Twice daily application of retinaldehyde 0.1% and 0.05% creams for 3 months improved skin texture and hydration and reduced transepidermal water loss in 40 female Korean volunteers, with only the 0.1% cream significantly improving the melanin index. ([Journal of Cosmetic Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29663701/))
- Topical retinaldehyde demonstrated significant antibacterial activity against gram-positive bacteria both in vitro and in vivo, leading to decreased bacterial counts without inducing resistance. ([Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12218231/))
- Topical 0.05% retinaldehyde applied over 1 year significantly increased epidermal thickness of the temple and cutaneous elasticity compared to an emollient control group in 40 aging skin patients. ([Dermatology, 1999](https://pubmed.ncbi.nlm.nih.gov/10473959/))

## Why other moisturizers fit combination skin better

- A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38366684/))
- A peel-off facial mask containing myoinositol and trehalose-loaded liposomes improved adult female acne by decreasing lesion counts, sebum production, GAGS scores, and local androgen levels while increasing beclin-1 levels. ([Journal of Cosmetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28342238/))
- Gluconolactone chemical peels lower skin pH and transepidermal water loss while demonstrating seboregulatory properties in 16 female subjects. ([Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37335807/))

## What reviewers say

This serum is highly praised for providing an immediate radiant glow and deep hydration, leaving skin feeling plump and bouncy. A significant number of users note a rich, tacky finish that may not be ideal for oily skin types or for use under makeup.

- Liked: Instant glow (mostly mentioned)
- Disliked: Sticky finish (mostly mentioned)
- Liked: Deep hydration (often mentioned)
- Liked: Anti-aging effects (sometimes noted)
- Liked: Unique texture (sometimes noted)
- Disliked: Heavy/Greasy feel (sometimes noted)
- Disliked: Caused breakouts (rarely noted)
- Disliked: Messy application (rarely noted)

## How to apply

- Use this moisturizer in your AM and PM routine every day to control shine. Always pair with SPF in the morning.
- Apply this moisturizer after your cleanser and toner, right before your morning SPF.
- Gently press a small amount of the moisturizer into your skin and avoid harsh rubbing. Let it ⏳absorb for a minute.
- Apply the moisturizer on slightly damp skin to help it lock in moisture better. This keeps your combination skin balanced.
- Avoid the eye area when applying the moisturizer. Do a patch test before your first use.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does Medicube Collagen Glow Bubble Serum work for combination skin?

Medicube Collagen Glow Bubble Serum works moderately well for combination skin, offering safe hydration and plumping without irritation. However, because it lacks strong oil-balancing ingredients for your shiny areas, a product of this type needs effective oil-control ingredients, ceramides, and hyaluronic acid to better balance and maintain a radiant complexion.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this serum a good fit for combination skin?

This serum works for combination skin because it contains glycerin and sodium hyaluronate, which hydrate and plump dry areas without causing irritation or oily shine. A product of this type needs effective hydrating and skin-repairing ingredients, ceramides, hyaluronic acid, peptides, and niacinamide to balance moisture and control oil.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Water-Soluble Collagen do for combination skin?

Water-soluble collagen helps improve moisture and hydration in combination skin while keeping it soft and smooth. Regular use of cosmetic products containing collagen may also help reduce the appearance of wrinkles and support the general condition of the skin.
Sources: [Dermatology Practical & Conceptual, 2022](https://pubmed.ncbi.nlm.nih.gov/35223163/), [Current Issues in Molecular Biology, 2024](https://pubmed.ncbi.nlm.nih.gov/38534748/)

### What does Niacinamide do for combination skin?

Niacinamide helps balance oily areas by reducing excess shine and pore size while keeping dry patches hydrated and smooth. It also works to calm redness and even out skin tone, making it very suitable for combination skin.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### Where does this serum go in a skincare routine for combination skin?

This treatment goes in the evening routine after cleansing and before moisturizing. Combination skin works best with products that provide hydration while also helping to control excess oil and shine.

### Can I use this serum with vitamin C, and in what order?

You can use this serum with vitamin C by applying vitamin C in your morning routine and this treatment at night, as the formula includes retinal. This combination helps keep your skin bright and smooth while avoiding potential irritation from mixing powerful actives at the same time.

### How often should I use this serum?

This serum works well in the evening as part of your routine for combination skin. To achieve better results on oily shine, a product of this type needs more potent seboregulating ingredients.

### Can this serum clog pores, cause breakouts or purging for combination skin?

This serum is unlikely to cause breakouts or clog pores on combination skin, as it lacks harsh ingredients and is free from common irritants. However, a product for this skin needs ingredients that help balance oil and reduce shine while providing moisture.

### Can I use this serum around the eyes or on my body?

You can use this moisturizing treatment around the eyes and on the body because it has a safe formula with good skin tolerance. A product of this type needs ingredients that hydrate and balance oil, along with soothing agents, to properly care for combination skin.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/), [Polymers, 2023](https://pubmed.ncbi.nlm.nih.gov/37896378/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for combination skin

- [Torriden DIVE-IN Low Molecular Hyaluronic Acid Serum](https://lovi.care/skincare/ca/p/torriden/dive-in-low-molecular-hyaluronic-acid-serum/for/combination-skin) — High fit — CA$21.81 at Amazon
- [MISSHA Super Aqua Ultra Hyalron Ampoule](https://lovi.care/skincare/ca/p/missha/super-aqua-ultra-hyalron-ampoule/for/combination-skin) — Average fit — CA$37.99 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/ca/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — CA$44.95 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/ca/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — CA$37.60 at Amazon
- SPF: [CeraVe AM Facial Moisturizing Lotion](https://lovi.care/skincare/ca/p/cerave/am-facial-moisturizing-lotion-spf-30/for/combination-skin) — Superior fit — CA$20.96 at Amazon

## Where to buy

- Amazon.ca: CA$40.99 (https://www.amazon.ca/dp/B0BRMZQBCR?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- Shoppers Drug Mart: CA$29.00 (https://www.shoppersdrugmart.ca/medicube-pdrn-pink-collagen-glow-jelly-mist-serum/p/BB_8800289478772?variantCode=8800289478772)
Prices checked 10 Oct – 6 Nov 2026.

## Ingredients

Water, Glycerin, Propanediol, Water-Soluble Collagen, Glycereth-26, Cetyl Ethylhexanoate, Caprylic Capric Triglyceride, Polyglyceryl-10 Laurate, Niacinamide, 1,2-Hexanediol, Polyglycerin-3, Pentaerythrityl Tetraisostearate, Ammonium Acryloyldimethyltaurate Vp Copolymer, Sodium Lauroyl Glutamate, Gardenia Florida Fruit Extract, Butylene Glycol, Dextrin, Xanthan Gum, Hydroxyethyl Urea, Ethylhexylglycerin, Adenosine, Allantoin, Collagen Extract, Macadamia Ternifolia Seed Oil, Atelocollagen, Desamido Collagen, Hydrogenated Lecithin, Sodium Hyaluronate, Hydrolyzed Elastin, Hydrolyzed Collagen, Caprylyl Glycol, Cholesterol, Sodium Hyaluronate Crosspolymer, Hydrolyzed Sodium Hyaluronate, Hydrolyzed Hyaluronic Acid, Sorbitan Laurate, Silica, Retinal, Glutathione, Brassica Campestris Sterols, Thioctic Acid, Ceteth-5, Ceteth-3, Collagen, Collagen Amino Acids, Potassium Cetyl Phosphate, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Hydroxyethylcellulose, Acetyl Dipeptide-1 Cetyl Ester, Sodium Acetylated Hyaluronate, Procollagen, Hydroxypropyltrimonium Hyaluronate, Acetyl Hexapeptide-1, Palmitoyl Tripeptide-5, Disodium Edta, Acetyl Octapeptide-3, Soluble Collagen Crosspolymer, Rosin Hydrolyzed Collagen, Potassium Myristoyl Hydrolyzed Collagen
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/medicube/collagen-glow-bubble-serum/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/medicube/collagen-glow-bubble-serum/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/medicube/collagen-glow-bubble-serum/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/medicube/collagen-glow-bubble-serum/for/combination-skin
- France: https://lovi.care/skincare/fr/p/medicube/collagen-glow-bubble-serum/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/medicube/collagen-glow-bubble-serum/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/medicube/collagen-glow-bubble-serum/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/medicube/collagen-glow-bubble-serum/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/medicube/collagen-glow-bubble-serum/for/combination-skin (this page)
- Australia: https://lovi.care/skincare/au/p/medicube/collagen-glow-bubble-serum/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/medicube/collagen-glow-bubble-serum/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/medicube/collagen-glow-bubble-serum/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/medicube/collagen-glow-bubble-serum/for/combination-skin