# MEDI-PEEL Peptide 9 Volume White Cica All-in-one Essence for acne-prone skin

**Lovi Fit: High fit for acne-prone skin.**
Combination Skin Fit: High · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/ca/p/medi-peel/peptide-9-volume-white-cica-all-in-one-essence/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Brand: [MEDI-PEEL](https://lovi.care/skincare/ca/brands/medi-peel)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/ca/best/moisturizers)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for acne-prone skin; a few moisturizers fit it even better.

## Why this fit

- This formulation is highly suitable for your combination skin, as niacinamide helps regulate sebum production while Centella Asiatica Extract provides anti-inflammatory benefits to address your acne and breakouts.
- Sodium hyaluronate and allantoin further enhance hydration and soothe the skin, contributing to a balanced and comfortable complexion.
- The product is safe for your skin, with no reported irritation risks due to its gentle formulation and the inclusion of soothing ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ca/p/medi-peel/peptide-9-volume-white-cica-all-in-one-essence/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/ca/p/medi-peel/peptide-9-volume-white-cica-all-in-one-essence/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/ca/p/medi-peel/peptide-9-volume-white-cica-all-in-one-essence/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/ca/p/medi-peel/peptide-9-volume-white-cica-all-in-one-essence/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/ca/p/medi-peel/peptide-9-volume-white-cica-all-in-one-essence/for/acne-prone-skin): High (this page)
- [Skin with dark spots](https://lovi.care/skincare/ca/p/medi-peel/peptide-9-volume-white-cica-all-in-one-essence/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/ca/p/medi-peel/peptide-9-volume-white-cica-all-in-one-essence/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/ca/p/medi-peel/peptide-9-volume-white-cica-all-in-one-essence/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/ca/p/medi-peel/peptide-9-volume-white-cica-all-in-one-essence/for/oily-acne-prone-skin): High

## Key ingredients

Peptides, Centella Asiatica, Niacinamide, Sodium Hyaluronate, Allantoin

## What the research says

- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- SD-101 6% cream showed no statistically significant difference compared to vehicle in time to target wound closure or the proportion of patients achieving complete target wound closure within 3 months in patients with epidermolysis bullosa. ([Orphanet Journal of Rare Diseases, 2020](https://pubmed.ncbi.nlm.nih.gov/32576219/))
- Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer. ([The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016](https://pubmed.ncbi.nlm.nih.gov/27475700/))
- An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment. ([Aesthetic Plastic Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29948103/))
- Prophylactic application of a topical scar gel containing Allium cepae extract, allantoin, and heparin significantly improves patient-assessed scar color, stiffness, and irregularity compared to no treatment in women following a cesarean section. ([Journal of Drugs in Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/24509969/))

## What reviewers say

Based on limited data, this essence is celebrated for its unique oxygen bubble texture that fizzes upon application, providing deep hydration and a plumping effect. Users frequently report significant improvements in skin brightness and a calming effect on redness and irritation, contributing to a sought-after 'glass skin' appearance. Some users note a moderately sticky finish and a few mention a strong fragrance or occasional packaging issues.

- Liked: Unique Bubble Texture (mostly mentioned)
- Liked: Brightening & Glow (often mentioned)
- Liked: Deep Hydration (often mentioned)
- Liked: Soothing & Calming (often mentioned)
- Liked: Multifunctional (sometimes noted)
- Disliked: Sticky finish (sometimes noted)
- Disliked: Price (rarely noted)
- Disliked: Pump/Packaging Issues (rarely noted)
- Disliked: Strong fragrance (rarely noted)
- Disliked: Too Rich for Oily Skin (rarely noted)

## How to apply

- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help keep breakouts under control.
- Apply after your cleanser and toner, and make sure to use your SPF right after in the morning.
- Gently spread a small amount of moisturizer over your face using soft motions. Let it absorb into the skin for a minute before getting dressed or applying makeup.
- Apply on slightly damp skin to help lock in extra moisture. This keeps your combination skin balanced without feeling heavy.
- Avoid the eye area and do a patch test before your first use. Stop using if you feel any irritation.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes MEDI-PEEL Peptide 9 Volume White Cica All-in-one Essence a great fit for acne-prone skin?

This moisturizing treatment is a great fit because niacinamide helps balance oil production while Centella Asiatica calms breakouts and inflammation. Sodium hyaluronate and allantoin add deep hydration and keep your skin comfortable without any expected irritation.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### Which ingredients make this essence a good fit for acne-prone skin?

This essence is a great fit because niacinamide helps regulate oil, while Centella Asiatica and allantoin soothe breakouts and keep the skin calm. Sodium hyaluronate also adds gentle hydration without feeling heavy.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### What do Peptides do for acne-prone skin?

Peptides help calm acne-prone skin by reducing redness and soothing inflammation while supporting the skin barrier. Certain advanced peptide formulas also work to target acne-causing bacteria and help balance oil production.
Sources: [Biochemical Pharmacology, 2025](https://pubmed.ncbi.nlm.nih.gov/39662606/), [Bioresources and Bioprocessing, 2026](https://pubmed.ncbi.nlm.nih.gov/42219443/)

### What does Centella Asiatica do for acne-prone skin?

Centella asiatica helps calm acne-prone skin by reducing redness and soothing inflammation while supporting healing. It may also help manage breakouts by addressing factors like acne blemishes and irritation.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/)

### Where does it go in a skincare routine for acne-prone skin?

This moisturizing treatment goes in the evening step of your routine. It is a great fit for your skin because niacinamide helps balance oil production while Centella Asiatica reduces breakouts and inflammation.
Sources: [International Journal of Cosmetic Science, 2020](https://pubmed.ncbi.nlm.nih.gov/31461548/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Can I use this essence with retinol, and in what order?

Yes, you can use this essence with retinol, applying the essence first to keep your skin calm and hydrated. The soothing ingredients like Centella Asiatica and allantoin help reduce the dryness and irritation that often come with using retinol.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### How often should I use it?

You can use this moisturizing treatment daily in your evening routine, as treatments with active ingredients work best at night for simplicity and safety. Applying it regularly helps keep your skin balanced while addressing breakouts and supporting hydration.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this essence clog pores, cause breakouts or purging for acne-prone skin?

This essence is a great fit for acne-prone skin because niacinamide helps balance oil production while Centella Asiatica soothes breakouts. Sodium hyaluronate and allantoin keep the skin calm and hydrated without clogging pores, and the product is unlikely to cause irritation.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### Can I use it around the eyes or on my body?

This moisturizing treatment is a great fit for acne-prone skin and can be used on the body, but it is generally best to use a specialized eye cream for the thin skin around the eyes. Its gentle ingredients like niacinamide and Centella Asiatica help soothe and balance skin while keeping irritation unlikely.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Is this essence fragrance-free and alcohol-free?

It has no fragrance and contains drying alcohol (alcohol).

## Alternatives for acne-prone skin

- [MISSHA Super Aqua Ultra Hyalron Ampoule](https://lovi.care/skincare/ca/p/missha/super-aqua-ultra-hyalron-ampoule/for/acne-prone-skin) — Average fit — CA$37.99 at Amazon

## Pairs well with

- Cleanser: [B.LAB Matcha Hydrating Foam Cleanser](https://lovi.care/skincare/ca/p/b-lab/matcha-hydrating-foam-cleanser/for/acne-prone-skin) — Superior fit — CA$22.95 at Amazon
- Hydrating Toner: [Paula's Choice Resist Advanced Replenishing Toner](https://lovi.care/skincare/ca/p/paula-s-choice/advanced-replenishing-toner/for/acne-prone-skin) — Superior fit — CA$41.00 at Amazon
- SPF: [innisfree Daily UV Defense Mineral Sunscreen](https://lovi.care/skincare/ca/p/innisfree/daily-uv-defense-mineral-sunscreen/for/acne-prone-skin) — Superior fit — CA$24.50 at Amazon

## Where to buy

No store in Canada has a checked price for this product, so the page shows none.

## Ingredients

Water, Glycerin, Methylpropanediol, Methyl Perfluoroisobutyl Ether, Hydrogenated Polyisobutene, Butylene Glycol Dicaprylate Dicaprate, Caprylic Capric Triglyceride, Methyl Perfluorobutyl Ether, Niacinamide, Cyclopentasiloxane, Cetearyl Alcohol, Cyclohexasiloxane, Palm Oil, Sodium Myristoyl Glutamate, Arginine, Glyceryl Stearate, Peg-100 Stearate, Decyl Glucoside, Betaine, Hydrogenated Lecithin, Hydroxyethyl Urea, Palm Kernel Oil, Dimethicone, Decylene Glycol, Ammonium Acryloyldimethyltaurate Vp Copolymer, Myristic Acid, Hexylene Glycol, Carbomer, Propanediol, Eucalyptus Globulus Leaf Extract, Juniperus Communis Fruit Extract, Butylene Glycol, Dimethicone Vinyl Dimethicone Crosspolymer, Glyceryl Acrylate Acrylic Acid Copolymer, Sodium Hyaluronate Crosspolymer, Urea, Allantoin, Ammonium Lactate, Adenosine, Sodium Hyaluronate, Hydrolyzed Glycosaminoglycans, Laureth-23, Propylene Glycol, Disodium Edta, Buteth-3, Centella Asiatica Extract, Centella Asiatica Leaf Extract, Anthemis Nobilis Flower Water, Argania Spinosa Kernel Oil, Camellia Sinensis Leaf Extract, Magnolia Officinalis Bark Extract, Fructan, Dandelion Root Extract Rhizome, Sodium Benzotriazolyl Butylphenol Sulfonate, Benzyl Glycol, Alcohol, Decyl Alcohol, Tris Tetramethylhydroxypiperidinol Citrate, Hydrolyzed Hyaluronic Acid, Glucose, Desamido Collagen, Hydrolyzed Collagen, Tranexamic Acid, Tributyl Citrate, Trideceth-6, Sodium Polyacrylate, Pentylene Glycol, Hydrogenated Polydecene, Glyceryl Polymethacrylate, Anemarrhena Asphodeloides Root Extract, Chamaecyparis Obtusa Leaf Extract, Asiaticoside, Origanum Vulgare Leaf Extract, Willow Bark Extract, Lactobacillus Soybean Extract Ferment, Cinnamomum Cassia Bark Extract, Scutellaria Baicalensis Root Extract, Portulaca Oleracea Extract, Sorbitan Laurate, Polysorbate 20, Raspberry Ketone, Polysorbate 80, Chondrus Crispus Extract, Hydroxyethylcellulose, Acetyl Dipeptide-1 Cetyl Ester, Astaxanthin, Hydrolyzed Elastin, Palmitoyl Tripeptide-5, Madecassoside, Madecassic Acid, Acetyl Hexapeptide-8, Copper Tripeptide-1, Asiatic Acid, Oligopeptide-29, Oligopeptide-32, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Palmitoyl Oligopeptide, Palmitoyl Pentapeptide-4, 1,2-Hexanediol, Ethylhexylglycerin, Totarol, Caprylyl Glycol, Ci 42090, Ci 15985, Ci 19140
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/medi-peel/peptide-9-volume-white-cica-all-in-one-essence/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/medi-peel/peptide-9-volume-white-cica-all-in-one-essence/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/medi-peel/peptide-9-volume-white-cica-all-in-one-essence/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/medi-peel/peptide-9-volume-white-cica-all-in-one-essence/for/acne-prone-skin
- France: https://lovi.care/skincare/fr/p/medi-peel/peptide-9-volume-white-cica-all-in-one-essence/for/acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/medi-peel/peptide-9-volume-white-cica-all-in-one-essence/for/acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/medi-peel/peptide-9-volume-white-cica-all-in-one-essence/for/acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/medi-peel/peptide-9-volume-white-cica-all-in-one-essence/for/acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/medi-peel/peptide-9-volume-white-cica-all-in-one-essence/for/acne-prone-skin (this page)
- Australia: https://lovi.care/skincare/au/p/medi-peel/peptide-9-volume-white-cica-all-in-one-essence/for/acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/medi-peel/peptide-9-volume-white-cica-all-in-one-essence/for/acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/medi-peel/peptide-9-volume-white-cica-all-in-one-essence/for/acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/medi-peel/peptide-9-volume-white-cica-all-in-one-essence/for/acne-prone-skin