# Medi-Peel Bor-Tox Peptide Ampoule for dry skin

**Lovi Fit: High fit for dry skin.**
Dry Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/ca/p/medi-peel/bor-tox-peptide-ampoule/for/dry-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Brand: [Medi-Peel](https://lovi.care/skincare/ca/brands/medi-peel)
Category: [Serums and treatments](https://lovi.care/skincare/ca/best/serums)

This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for dry skin; a few serums fit it even better.

## Why this fit

- This product offers excellent treatment for your dry skin, as peptides like copper tripeptide-1 and acetyl hexapeptide-8 work to minimize fine lines and wrinkles. Sodium hyaluronate and hydrolyzed collagen provide essential hydration and improve skin elasticity, directly addressing your dry or flaky skin concerns.
- The formula is highly suitable for dry skin due to the humectant and collagen-boosting actions of sodium hyaluronate and hydrolyzed collagen, respectively.
- The safety profile is excellent, with no risks of irritation for your dry skin due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ca/p/medi-peel/bor-tox-peptide-ampoule/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/ca/p/medi-peel/bor-tox-peptide-ampoule/for/dry-skin): High (this page)
- [Combination skin](https://lovi.care/skincare/ca/p/medi-peel/bor-tox-peptide-ampoule/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/ca/p/medi-peel/bor-tox-peptide-ampoule/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/ca/p/medi-peel/bor-tox-peptide-ampoule/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/ca/p/medi-peel/bor-tox-peptide-ampoule/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/ca/p/medi-peel/bor-tox-peptide-ampoule/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/ca/p/medi-peel/bor-tox-peptide-ampoule/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/ca/p/medi-peel/bor-tox-peptide-ampoule/for/oily-acne-prone-skin): High

## Key ingredients

5 Peptide Complex, Hydrolyzed Collagen, Sodium Hyaluronate, Copper Tripeptide-1, Fermentation Complex

## What the research says

- Argireline treatment twice daily for 4 weeks produced a significant anti-wrinkle effect with 48.9% total efficacy and decreased skin roughness in Chinese subjects compared with 0% efficacy and no decrease in roughness in the placebo group. ([American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/))
- Treatment with cross-linked hyaluronic acid-based microneedle patches combined with acetyl hexapeptide-8 or epidermal growth factor significantly improved wrinkles and skin hydration compared to the patch alone in Korean females over 29 days. ([Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/))
- Argireline applied twice daily for 4 weeks achieved a total anti-wrinkle efficiency of 48.9% and notably reduced wrinkle depth compared to placebo in Chinese subjects. ([Journal of Cosmetic and Laser Therapy, 2013](https://pubmed.ncbi.nlm.nih.gov/23607739/))
- Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/))
- Topical application of TAC/Collagen postbiotics gel improved skin moisture score and inflammation index, and reduced porphyrins and brown spots in 20 volunteers with acne vulgaris. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35818134/))
- Topical collagen tripeptide application improved skin wrinkles, elasticity, and density while reducing advanced glycated end products in 22 Asian women over 4 weeks. ([International Journal of Molecular Sciences, 2022](https://pubmed.ncbi.nlm.nih.gov/35163025/))
- Marine collagen extracted from Greenland halibut skin showed a non-cytotoxic effect on fibroblast cells and provided a slight skin hydration effect when incorporated into cosmetic hydrogel formulations at dosages of 0.1, 0.25, and 0.5% in 23 healthy volunteers. ([Marine Drugs, 2023](https://pubmed.ncbi.nlm.nih.gov/36827098/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical copper tripeptide complex on CO2 laser-resurfaced skin caused no significant reduction in erythema or objective improvement in wrinkles compared to controls, but significantly increased patient satisfaction regarding overall skin quality. ([Archives of Facial Plastic Surgery, 2006](https://pubmed.ncbi.nlm.nih.gov/16847171/))
- A novel regimen combining a hydroxy acid-based scrub and copper tripeptide serum significantly reduced adherent scalp flaking by 61.24%, increased hair density by 12.48%, increased hair thickness by 25.36%, and improved scalp skin hydration by 76.24% in adults with mild to moderate dandruff over 15 days. ([Cureus, 2024](https://pubmed.ncbi.nlm.nih.gov/39449909/))
- The combination of Thermus thermophilus and Bacillus subtilis mixed-culture ferment extract and copper tripeptide-1 GHK-Cu reduced inflammatory cytokines, protected skin explants from UV-induced damage, and improved wrinkles and skin barrier conditions compared to individual components or controls. ([Skin Research and Technology, 2026](https://pubmed.ncbi.nlm.nih.gov/42573538/))
- A combination serum containing galactomyces ferment filtrate, dexpanthenol, and Centella asiatica effectively treated post-acne hyperpigmentation in subjects with colored skin by significantly increasing lightness scores in Fitzpatrick skin type V and reducing the melanin index in Fitzpatrick skin type IV compared to placebo. ([Skinmed, 2021](https://pubmed.ncbi.nlm.nih.gov/33938432/))
- Application of Galactomyces ferment filtrate skin care formula significantly reduced the net values and daily fluctuation of facial pore area, roughness, and redness in young Japanese women. ([Journal of Clinical Medicine, 2021](https://pubmed.ncbi.nlm.nih.gov/34198790/))
- Galactomyces ferment filtrate promotes epidermal interconnectivity, barrier development, cell adhesion, keratinocyte differentiation and proliferation, and protects cellular bioenergetics against stress in keratinocytes and ex vivo skin explants compared to untreated controls. ([International Journal of Cosmetic Science, 2024](https://pubmed.ncbi.nlm.nih.gov/38924095/))

## What reviewers say

Based on a very large amount of data, this ampoule is widely praised for its ability to deeply hydrate and plump the skin, resulting in a bouncy, youthful glow that softens fine lines. Many users appreciate its milky, non-sticky texture and suitability for sensitive skin. Some users find the anti-aging claims exaggerated and struggle with the inefficient dropper packaging.

- Liked: Deep hydration & plumping (mostly mentioned)
- Liked: Elegant texture (often mentioned)
- Liked: Smoother skin texture (often mentioned)
- Disliked: Poor dropper design (often mentioned)
- Liked: Gentle on sensitive skin (sometimes noted)
- Disliked: Divisive scent (sometimes noted)
- Disliked: Lack of dramatic anti-aging (sometimes noted)
- Disliked: Small quantity/value (rarely noted)

## How to apply

- Apply this serum PM, starting 3×/week and working up to daily use as your skin adjusts.
- Place the serum after cleansing and toner, but right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on slightly damp skin to help lock in extra moisture.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Medi-Peel Bor-Tox Peptide Ampoule a great fit for dry skin?

Medi-Peel Bor-Tox Peptide Ampoule is a great fit because sodium hyaluronate and hydrolyzed collagen bring essential moisture to flaky skin while smoothing out fine lines. Copper tripeptide-1 and acetyl hexapeptide-8 help improve skin firmness and target wrinkles safely without causing irritation.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/), [Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/)

### Which ingredients make this serum a good fit for dry skin?

This serum is a great fit for dry skin because sodium hyaluronate and hydrolyzed collagen provide deep hydration while copper tripeptide-1 and acetyl hexapeptide-8 help smooth out fine lines. These ingredients work together to relieve dry, flaky skin and improve overall elasticity with very little risk of irritation.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/), [Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/)

### What does Peptide Complex do for dry skin?

Peptide Complex helps keep dry skin hydrated and smooth. Studies show that peptide supplements can increase skin water content, improve elasticity, and help maintain a healthy moisture barrier.
Sources: [Skin Pharmacology and Physiology, 2021](https://pubmed.ncbi.nlm.nih.gov/33774639/), [Journal of Microbiology and Biotechnology, 2025](https://pubmed.ncbi.nlm.nih.gov/40935395/)

### What does Hydrolyzed Collagen do for dry skin?

Hydrolyzed Collagen helps improve skin moisture and keeps dry skin hydrated. Regular use may also reduce wrinkles and make the skin feel more smooth and elastic.
Sources: [Cureus, 2023](https://pubmed.ncbi.nlm.nih.gov/38192916/), [International Journal of Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33742704/)

### Where does this serum go in a skincare routine for dry skin?

This treatment goes in your evening routine after cleansing and before your moisturizer. Applying it at night helps keep your skin safe around sun exposure while delivering rich hydration.

### Can I use it with retinol, and in what order?

You can use this treatment with retinol by applying retinol first, letting it absorb, and then following with this ampoule. This helps keep your dry skin comfortable while providing deep hydration and minimizing fine lines.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/), [Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/)

### How often should I use this serum?

This treatment is used in your evening routine, applying it after cleansing and before your moisturizer. It is gentle enough for daily use to help smooth fine lines and keep dry skin feeling soft and hydrated.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/), [Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/)

### Can it clog pores, cause breakouts or purging for dry skin?

This product is unlikely to clog pores, cause breakouts or trigger purging on dry skin due to the absence of harsh or pore-clogging ingredients. Its gentle formula has an excellent safety profile, making it very safe for daily use without irritation.

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for dry skin

- [KraveBeauty Great Barrier Relief](https://lovi.care/skincare/ca/p/kravebeauty/great-barrier-relief/for/dry-skin) — Superior fit — CA$40.00 at Amazon
- [SKIN1004 Madagascar Centella Tone Brightening Capsule Ampoule](https://lovi.care/skincare/ca/p/skin1004/madagascar-centella-tone-brightening-capsule-ampoule/for/dry-skin) — Superior fit — CA$22.49 at Amazon
- [The Ordinary Matrixyl 10% + HA](https://lovi.care/skincare/ca/p/the-ordinary/matrixyl-10-ha/for/dry-skin) — Superior fit — CA$14.40 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/ca/p/cerave/hydrating-facial-cleanser/for/dry-skin) — Superior fit — CA$20.19 at Amazon
- Hydrating Toner: [Dear, Klairs Supple Preparation Unscented Toner](https://lovi.care/skincare/ca/p/dear-klairs/supple-preparation-unscented-toner/for/dry-skin) — Superior fit — CA$27.99 at Amazon
- Moisturizer: [Tata Harper Repairative Moisturizer](https://lovi.care/skincare/ca/p/tata-harper/repairative-moisturizer/for/dry-skin) — Superior fit — CA$162.00 at Amazon

## Where to buy

No store in Canada has a checked price for this product, so the page shows none.

## Ingredients

Hydrolyzed Collagen, Water, Butylene Glycol, Hydrogenated Polyisobutene, 1,2-Hexanediol, Polyacrylamide, Lactobacillus Pumpkin Extract Ferment, Lactobacillus Soybean Extract Ferment, C13-14 Isoparaffin, Polysorbate 20, Arginine, Lactobacillus Punica Granatum Extract Fruit Ferment, Lactobacillus Wasabia Japonica Extract Root Ferment, Sodium Hyaluronate, Ethylhexylglycerin, Saccharomyces Grape Extract Ferment, Carbomer, Allantoin, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Saccharomyces Ferment Filtrate, Laureth-7, Bifida Lysate Ferment, Disodium Edta, Adenosine, Leontopodium Alpinum Callus Culture Extract, Hydrolyzed Elastin, Gardenia Florida Fruit Extract, Anemarrhena Asphodeloides Root Extract, Inonotus Obliquus Extract Mushroom Extract, Palm Oil, Copper Tripeptide-1, Acetyl Hexapeptide-8, Oligopeptide-32, Oligopeptide-29, Palmitoyl Pentapeptide-4
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/medi-peel/bor-tox-peptide-ampoule/for/dry-skin
- United Kingdom: https://lovi.care/skincare/uk/p/medi-peel/bor-tox-peptide-ampoule/for/dry-skin
- Ireland: https://lovi.care/skincare/ie/p/medi-peel/bor-tox-peptide-ampoule/for/dry-skin
- Germany: https://lovi.care/skincare/de/p/medi-peel/bor-tox-peptide-ampoule/for/dry-skin
- France: https://lovi.care/skincare/fr/p/medi-peel/bor-tox-peptide-ampoule/for/dry-skin
- Italy: https://lovi.care/skincare/it/p/medi-peel/bor-tox-peptide-ampoule/for/dry-skin
- Netherlands: https://lovi.care/skincare/nl/p/medi-peel/bor-tox-peptide-ampoule/for/dry-skin
- Spain: https://lovi.care/skincare/es/p/medi-peel/bor-tox-peptide-ampoule/for/dry-skin
- Canada: https://lovi.care/skincare/ca/p/medi-peel/bor-tox-peptide-ampoule/for/dry-skin (this page)
- Australia: https://lovi.care/skincare/au/p/medi-peel/bor-tox-peptide-ampoule/for/dry-skin
- Singapore: https://lovi.care/skincare/sg/p/medi-peel/bor-tox-peptide-ampoule/for/dry-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/medi-peel/bor-tox-peptide-ampoule/for/dry-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/medi-peel/bor-tox-peptide-ampoule/for/dry-skin