# Medi-Peel Bor-Tox Peptide Ampoule for combination skin

**Lovi Fit: High fit for combination skin.**
Combination Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/ca/p/medi-peel/bor-tox-peptide-ampoule/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Brand: [Medi-Peel](https://lovi.care/skincare/ca/brands/medi-peel)
Category: [Serums and treatments](https://lovi.care/skincare/ca/best/serums)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for combination skin; a few serums fit it even better.

## Why this fit

- Offers excellent wrinkle reduction for your combination skin, as peptides like acetyl hexapeptide-8 and copper tripeptide-1 work to plump and minimize fine lines by supporting skin elasticity and reducing pore appearance. Sodium hyaluronate and hydrolyzed collagen further enhance your combination skin by providing humectant and collagen-boosting actions, respectively.
- The formula is highly suitable for your combination skin, with ingredients like sodium hyaluronate and hydrolyzed collagen providing essential hydration and collagen support.
- The safety profile is excellent, with no risks of irritation for your combination skin due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ca/p/medi-peel/bor-tox-peptide-ampoule/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/ca/p/medi-peel/bor-tox-peptide-ampoule/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/ca/p/medi-peel/bor-tox-peptide-ampoule/for/combination-skin): High (this page)
- [Sensitive skin](https://lovi.care/skincare/ca/p/medi-peel/bor-tox-peptide-ampoule/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/ca/p/medi-peel/bor-tox-peptide-ampoule/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/ca/p/medi-peel/bor-tox-peptide-ampoule/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/ca/p/medi-peel/bor-tox-peptide-ampoule/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/ca/p/medi-peel/bor-tox-peptide-ampoule/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/ca/p/medi-peel/bor-tox-peptide-ampoule/for/oily-acne-prone-skin): High

## Key ingredients

5 Peptide Complex, Hydrolyzed Collagen, Sodium Hyaluronate, Copper Tripeptide-1, Fermentation Complex

## What the research says

- Argireline treatment twice daily for 4 weeks produced a significant anti-wrinkle effect with 48.9% total efficacy and decreased skin roughness in Chinese subjects compared with 0% efficacy and no decrease in roughness in the placebo group. ([American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/))
- Treatment with cross-linked hyaluronic acid-based microneedle patches combined with acetyl hexapeptide-8 or epidermal growth factor significantly improved wrinkles and skin hydration compared to the patch alone in Korean females over 29 days. ([Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/))
- Argireline applied twice daily for 4 weeks achieved a total anti-wrinkle efficiency of 48.9% and notably reduced wrinkle depth compared to placebo in Chinese subjects. ([Journal of Cosmetic and Laser Therapy, 2013](https://pubmed.ncbi.nlm.nih.gov/23607739/))
- Cod skin collagen peptide/chitosan-based temperature-sensitive gel (CS/CSCPs/β-GP gel) synergistically enhanced the anti-photoaging effect of CSCPs in an ultraviolet-irradiated mouse model by inhibiting ROS, suppressing inflammatory factors, and preventing collagen degradation. ([Drug Design, Development and Therapy, 2023](https://pubmed.ncbi.nlm.nih.gov/36798808/))
- Topical application of TAC/Collagen postbiotics gel improved skin moisture score and inflammation index, and reduced porphyrins and brown spots in 20 volunteers with acne vulgaris. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35818134/))
- Topical collagen tripeptide application improved skin wrinkles, elasticity, and density while reducing advanced glycated end products in 22 Asian women over 4 weeks. ([International Journal of Molecular Sciences, 2022](https://pubmed.ncbi.nlm.nih.gov/35163025/))
- Marine collagen extracted from Greenland halibut skin showed a non-cytotoxic effect on fibroblast cells and provided a slight skin hydration effect when incorporated into cosmetic hydrogel formulations at dosages of 0.1, 0.25, and 0.5% in 23 healthy volunteers. ([Marine Drugs, 2023](https://pubmed.ncbi.nlm.nih.gov/36827098/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical copper tripeptide complex on CO2 laser-resurfaced skin caused no significant reduction in erythema or objective improvement in wrinkles compared to controls, but significantly increased patient satisfaction regarding overall skin quality. ([Archives of Facial Plastic Surgery, 2006](https://pubmed.ncbi.nlm.nih.gov/16847171/))
- A novel regimen combining a hydroxy acid-based scrub and copper tripeptide serum significantly reduced adherent scalp flaking by 61.24%, increased hair density by 12.48%, increased hair thickness by 25.36%, and improved scalp skin hydration by 76.24% in adults with mild to moderate dandruff over 15 days. ([Cureus, 2024](https://pubmed.ncbi.nlm.nih.gov/39449909/))
- The combination of Thermus thermophilus and Bacillus subtilis mixed-culture ferment extract and copper tripeptide-1 GHK-Cu reduced inflammatory cytokines, protected skin explants from UV-induced damage, and improved wrinkles and skin barrier conditions compared to individual components or controls. ([Skin Research and Technology, 2026](https://pubmed.ncbi.nlm.nih.gov/42573538/))
- A combination serum containing galactomyces ferment filtrate, dexpanthenol, and Centella asiatica effectively treated post-acne hyperpigmentation in subjects with colored skin by significantly increasing lightness scores in Fitzpatrick skin type V and reducing the melanin index in Fitzpatrick skin type IV compared to placebo. ([Skinmed, 2021](https://pubmed.ncbi.nlm.nih.gov/33938432/))
- Application of Galactomyces ferment filtrate skin care formula significantly reduced the net values and daily fluctuation of facial pore area, roughness, and redness in young Japanese women. ([Journal of Clinical Medicine, 2021](https://pubmed.ncbi.nlm.nih.gov/34198790/))
- Galactomyces ferment filtrate promotes epidermal interconnectivity, barrier development, cell adhesion, keratinocyte differentiation and proliferation, and protects cellular bioenergetics against stress in keratinocytes and ex vivo skin explants compared to untreated controls. ([International Journal of Cosmetic Science, 2024](https://pubmed.ncbi.nlm.nih.gov/38924095/))

## What reviewers say

Based on a very large amount of data, this ampoule is widely praised for its ability to deeply hydrate and plump the skin, resulting in a bouncy, youthful glow that softens fine lines. Many users appreciate its milky, non-sticky texture and suitability for sensitive skin. Some users find the anti-aging claims exaggerated and struggle with the inefficient dropper packaging.

- Liked: Deep hydration & plumping (mostly mentioned)
- Liked: Elegant texture (often mentioned)
- Liked: Smoother skin texture (often mentioned)
- Disliked: Poor dropper design (often mentioned)
- Liked: Gentle on sensitive skin (sometimes noted)
- Disliked: Divisive scent (sometimes noted)
- Disliked: Lack of dramatic anti-aging (sometimes noted)
- Disliked: Small quantity/value (rarely noted)

## How to apply

- Use your serum as part of your PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
- Apply the serum after cleansing and toner, and right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏳for it to soak in.
- Apply the serum on clean and dry skin since your skin is not sensitive.
- Always do a patch test before using the serum for the first time, and avoid the eye area .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Medi-Peel Bor-Tox Peptide Ampoule a great fit for combination skin?

Medi-Peel Bor-Tox Peptide Ampoule is a great fit for your combination skin because it offers excellent wrinkle reduction and hydration while keeping your skin calm. Peptides like acetyl hexapeptide-8 and copper tripeptide-1 help plump fine lines and reduce pore appearance, while sodium hyaluronate and hydrolyzed collagen deliver essential moisture. It also has a very safe profile with no harsh ingredients, meaning it is unlikely to cause irritation.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/), [Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/)

### Which ingredients make this serum a good fit for combination skin?

This serum is a great fit for combination skin because it features peptides like acetyl hexapeptide-8 and copper tripeptide-1 to smooth fine lines, along with sodium hyaluronate and hydrolyzed collagen to deliver essential hydration. These ingredients help plump the skin and improve elasticity without causing irritation.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/), [Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/)

### What does Peptide Complex do for combination skin?

Peptide Complex helps hydrate combination skin, improve elasticity, and smooth the look of lines with daily use. It is unlikely to cause irritation and may also help firm the skin over time.
Sources: [Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30834689/), [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37335808/)

### What does Hydrolyzed Collagen do for combination skin?

Hydrolyzed collagen helps keep combination skin hydrated and smooth while improving elasticity and reducing the look of fine lines. This type of supplement is generally well tolerated and may support overall skin firmness across different facial areas.
Sources: [Cureus, 2023](https://pubmed.ncbi.nlm.nih.gov/38192916/), [Journal of Cosmetic Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/26362110/)

### Where does this serum go in a skincare routine for combination skin?

This treatment goes in your evening routine after cleansing and toning, and before moisturizing. Putting active serums in the evening helps keep things simple and provides extra safety around sun exposure.

### Can I use this serum with retinol, and in what order?

Yes, you can use this serum with retinol by applying the serum first and following it with your retinol product. This approach helps your skin stay smooth and hydrated while minimizing any potential irritation from the retinol.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/), [Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/)

### How often should I use this serum?

This serum is used in your evening routine, applying it after your cleansing toner and before your moisturizer. It is unlikely to cause irritation for your combination skin, and certain peptide formulas may be used twice a day for enhanced results.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/), [Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/)

### Can this serum clog pores, cause breakouts or purging for combination skin?

This serum is unlikely to clog pores or cause breakouts for combination skin. The safety profile is excellent, with no harsh ingredients that typically trigger irritation or breakouts for this skin type.

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for combination skin

- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/ca/p/skin1004/probio-cica-intensive-ampoule/for/combination-skin) — High fit — CA$24.44 at Amazon
- [Dr.Althea Vitamin C Boosting Serum](https://lovi.care/skincare/ca/p/dr-althea/vitamin-c-boosting-serum/for/combination-skin) — High fit — CA$27.99 at Amazon
- [COSRX The Vitamin C 23 Serum](https://lovi.care/skincare/ca/p/cosrx/the-vitamin-c-23-serum/for/combination-skin) — Average fit — CA$33.98 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/ca/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — CA$44.95 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/ca/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — CA$37.60 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/ca/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/combination-skin) — Superior fit — CA$29.98 at Amazon

## Where to buy

No store in Canada has a checked price for this product, so the page shows none.

## Ingredients

Hydrolyzed Collagen, Water, Butylene Glycol, Hydrogenated Polyisobutene, 1,2-Hexanediol, Polyacrylamide, Lactobacillus Pumpkin Extract Ferment, Lactobacillus Soybean Extract Ferment, C13-14 Isoparaffin, Polysorbate 20, Arginine, Lactobacillus Punica Granatum Extract Fruit Ferment, Lactobacillus Wasabia Japonica Extract Root Ferment, Sodium Hyaluronate, Ethylhexylglycerin, Saccharomyces Grape Extract Ferment, Carbomer, Allantoin, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Saccharomyces Ferment Filtrate, Laureth-7, Bifida Lysate Ferment, Disodium Edta, Adenosine, Leontopodium Alpinum Callus Culture Extract, Hydrolyzed Elastin, Gardenia Florida Fruit Extract, Anemarrhena Asphodeloides Root Extract, Inonotus Obliquus Extract Mushroom Extract, Palm Oil, Copper Tripeptide-1, Acetyl Hexapeptide-8, Oligopeptide-32, Oligopeptide-29, Palmitoyl Pentapeptide-4
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/medi-peel/bor-tox-peptide-ampoule/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/medi-peel/bor-tox-peptide-ampoule/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/medi-peel/bor-tox-peptide-ampoule/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/medi-peel/bor-tox-peptide-ampoule/for/combination-skin
- France: https://lovi.care/skincare/fr/p/medi-peel/bor-tox-peptide-ampoule/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/medi-peel/bor-tox-peptide-ampoule/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/medi-peel/bor-tox-peptide-ampoule/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/medi-peel/bor-tox-peptide-ampoule/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/medi-peel/bor-tox-peptide-ampoule/for/combination-skin (this page)
- Australia: https://lovi.care/skincare/au/p/medi-peel/bor-tox-peptide-ampoule/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/medi-peel/bor-tox-peptide-ampoule/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/medi-peel/bor-tox-peptide-ampoule/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/medi-peel/bor-tox-peptide-ampoule/for/combination-skin