# Mary Kay Timewise Night Solution for sensitive skin

**Lovi Fit: Average fit for sensitive skin.**
Normal Skin Fit: Average · Effectiveness: Average · Safety: Concerning.

Page: https://lovi.care/skincare/ca/p/mary-kay/timewise-night-solution/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Brand: [Mary Kay](https://lovi.care/skincare/ca/brands/mary-kay)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/ca/best/moisturizers)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for sensitive skin; other moisturizers fit it better.

## Why this fit

- Suitable for normal skin, this formulation offers moderate moisturizing and anti-aging benefits due to glycerin for hydration and palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7 for smoothing texture, though these are not directly targeted at your redness and irritation concerns.
- The presence of Anthemis Nobilis Flower Extract and Rosa Centifolia Flower Extract provides soothing effects, which are generally beneficial for sensitive skin.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ca/p/mary-kay/timewise-night-solution/for/oily-skin): Low
- [Dry skin](https://lovi.care/skincare/ca/p/mary-kay/timewise-night-solution/for/dry-skin): Low
- [Combination skin](https://lovi.care/skincare/ca/p/mary-kay/timewise-night-solution/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/ca/p/mary-kay/timewise-night-solution/for/sensitive-skin): Average (this page)
- [Acne-prone skin](https://lovi.care/skincare/ca/p/mary-kay/timewise-night-solution/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/ca/p/mary-kay/timewise-night-solution/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/ca/p/mary-kay/timewise-night-solution/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/ca/p/mary-kay/timewise-night-solution/for/dry-sensitive-skin): Low
- [Oily acne-prone skin](https://lovi.care/skincare/ca/p/mary-kay/timewise-night-solution/for/oily-acne-prone-skin): Average

## Key ingredients

Palmitoyl Tripeptide-1, Retinyl Palmitate, Tocopheryl Acetate, Glycerin, Crithmum Maritimum Extract

## What the research says

- Chronomodulated daytime application of baicalin and nighttime application of palmitoyl tripeptide-1 synergistically improved skin luminance by 16.29%, nasolabial fold depth by -36.35%, and firmness by 24.35% in 30 female participants. ([Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/))
- A multi-modal methodology combining MALDI-MSI, in vivo RCM, echography, and histology revealed age-related decreases in extracellular matrix and epidermal-dermal junction proteins and undulation depth, while a blend of palmitoyl oligopeptide and palmitoyl tetrapeptide-7 improved subepidermal low-echogenic band thickness, density, and extracellular matrix structure compared to placebo. ([Journal of Cosmetic Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25817264/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Palmitoyl tetrapeptide-7, acetyl hexapeptide-8, palmitoyl tripeptide-1, and palmitoyl tetrapeptide-10 significantly increased type III collagen levels in human dermal fibroblasts following UV exposure, with their combination demonstrating a greater effect in vitro and enhancing type I, III, and IV collagen levels in ex vivo skin tissues compared to individual components. ([International Journal of Cosmetic Science, 2026](https://pubmed.ncbi.nlm.nih.gov/42683869/))
- Over-the-counter retinol products provided only weak evidence for a mild ameliorating effect on fine facial skin wrinkle lines in randomized, double-blind, vehicle-controlled trials, and major methodological flaws call the validity of positive results into question. ([The Journal of Clinical and Aesthetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/34980969/))
- A cosmetic niacinamide/peptide/retinyl propionate regimen significantly improved periorbital wrinkle appearance relative to a 0.02% tretinoin regimen at 8 weeks with comparable benefits at 24 weeks, while demonstrating significantly better tolerability in 196 women. ([The British Journal of Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/20374604/))
- A novel triple-active cosmetic formulation containing 4-hexylresorcinol, retinyl propionate, and niacinamide improved the visual appearance of photoageing similarly to 0.02% tretinoin and reversed a consensus gene signature associated with ageing in female adults while causing less skin irritation. ([International Journal of Cosmetic Science, 2024](https://pubmed.ncbi.nlm.nih.gov/38685700/))
- Topical application of an antioxidant serum containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented particulate matter-induced degradation of extracellular matrix components, inflammation, and oxidative stress in the skin of 15 female volunteers compared to untreated controls. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40642809/))
- Dermatological products containing d-alpha tocopheryl acetate showed non-comedogenic potential with less than a 50% increase in microcomedones in 12 healthy male subjects compared to octyl palmitate. ([Contemporary Clinical Trials Communications, 2021](https://pubmed.ncbi.nlm.nih.gov/34471722/))
- Topical application of an antioxidant mix containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented PM and UV-induced skin barrier perturbation, lipid peroxidation, inflammatory markers, MMP9 activation, and Type I collagen loss in 15 healthy females compared to untreated exposed skin. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38590207/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Preconditioning with samphire cell biomass formulations significantly accelerated epidermal permeability barrier repair kinetics after controlled stripping in healthy subjects older than 50 years compared to placebo and untreated sites. ([Journal of Cosmetic Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22151937/))
- Extracellular vesicles derived from Crithmum maritimum callus and miR167 promote wound healing and skin regeneration in human fibroblasts by downregulating MMP1 and upregulating COL1A1 and VEGFA without cytotoxicity. ([Biomolecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40867601/))
- The full-component extract of Crithmum maritimum significantly promotes epidermal regeneration of UV-induced skin damage in a barrier-weakening 3D full-skin model compared to oil-based extract components. ([RSC Advances, 2025](https://pubmed.ncbi.nlm.nih.gov/39835209/))

## Why other moisturizers fit sensitive skin better

- A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38366684/))
- A topical microemulsion containing Punica granatum extract significantly reduced skin erythema and melanin compared to a placebo in healthy Asian subjects over 12 weeks. ([Postepy Dermatologii I Alergologii, 2014](https://pubmed.ncbi.nlm.nih.gov/25610348/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))

## How to apply

- Use this soothing AM and PM routine every day to keep your normal skin calm. Always remember to apply SPF in the morning after your moisturizer.
- Apply your moisturizer after your toner in the morning, and after your serum in the evening. This step locks in hydration and protects your skin.
- Gently press a small amount of the moisturizer evenly across your face. Avoid rubbing to keep your sensitive skin happy and calm.
- You can apply this gentle formula on dry or slightly damp skin for the best comfort. It works wonderfully on clean skin to soothe redness and irritation.
- Do a patch test before your very first use to check your skin's reaction. Avoid getting the product directly into your eyes .
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does Timewise Night Solution work for sensitive skin?

Mary Kay Timewise Night Solution works moderately well for sensitive skin, offering hydration and smoothing texture, though it does not directly target redness and irritation. Sensitive skin needs products that are highly effective in soothing and hydrating while calming redness with no risks, featuring safe concentrations of calming and moisturizing ingredients.
Sources: [Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/), [Journal of Cosmetic Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25817264/)

### Which ingredients make this serum a good fit for sensitive skin?

Anthemis Nobilis Flower Extract and Rosa Centifolia Flower Extract help soothe sensitive skin, while glycerin provides moisture. For sensitive skin to be a better fit, a moisturizing treatment needs ingredients that directly address redness and irritation with no associated risks while delivering optimal soothing and hydration.

### What does Palmitoyl Tripeptide-1 do for sensitive skin?

Palmitoyl tripeptide-1 helps smooth fine lines and improves firmness in sensitive skin. It works by supporting collagen levels to keep skin looking youthful and resilient.
Sources: [Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/), [International Journal of Cosmetic Science, 2026](https://pubmed.ncbi.nlm.nih.gov/42683869/)

### What does Retinyl Palmitate do for sensitive skin?

Retinyl palmitate helps improve fine lines, wrinkles, and texture, but for sensitive skin it requires careful testing because it may cause irritation. This skin type needs gentle, hydrating ingredients and barrier-repairing components to stay calm and comfortable.
Sources: [Journal of Cosmetic Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23438139/), [International Journal of Nanomedicine, 2021](https://pubmed.ncbi.nlm.nih.gov/34211271/)

### Where does this serum go in a skincare routine for sensitive skin?

This treatment goes in the evening routine, applied after your cleanser and soothing toner, and before your moisturizer. Sensitive skin needs a product of this type that also focuses on calming redness and irritation with soothing ingredients.

### Can I use this serum with niacinamide, and in what order?

You can use this treatment with niacinamide by applying niacinamide first and letting it absorb before adding this product. Sensitive skin needs a formula with soothing ingredients and extra hydration to keep the skin calm and comfortable.

### How often should I use this serum?

This treatment works well in the evening for sensitive skin, as part of a routine that helps keep skin calm and hydrated. Because it contains active ingredients that smooth texture, you may use it regularly at night, though a product for this skin also needs extra soothing ingredients to comfort redness.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this serum clog pores, cause breakouts or purging for sensitive skin?

This product is unlikely to clog pores for sensitive skin, though it is only a moderate fit since it lacks direct ingredients to calm redness and irritation. Sensitive skin needs a treatment with soothing plant extracts and gentle hydrators like glycerin to keep it calm and smooth without causing breakouts.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use this serum around the eyes or on my body?

This product works for sensitive skin, but because the eyelid and body skin are different from facial skin, a moisturizing treatment used there needs gentle soothing plant extracts and lightweight hydrators to keep thin skin soft without irritation.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for sensitive skin

- [innisfree Green Tea Seed Hyaluronic Acid Hydrating Serum](https://lovi.care/skincare/ca/p/innisfree/green-tea-seed-hyaluronic-acid-hydrating-serum/for/sensitive-skin) — High fit — CA$40.50 at Amazon
- [Torriden DIVE-IN Low Molecular Hyaluronic Acid Serum](https://lovi.care/skincare/ca/p/torriden/dive-in-low-molecular-hyaluronic-acid-serum/for/sensitive-skin) — High fit — CA$21.81 at Amazon
- [Elizavecca Witch Piggy Hell Pore Control Hyaluronic Acid 97%](https://lovi.care/skincare/ca/p/elizavecca/witch-piggy-hell-pore-control-hyaluronic-acid-97/for/sensitive-skin) — High fit — CA$25.99 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/ca/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — CA$44.95 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/ca/p/clarins/soothing-toning-lotion/for/sensitive-skin) — Superior fit — CA$49.00 at Amazon
- Moisturizer with Sun Protection: [Torriden DIVE-IN Mild Sunscreen](https://lovi.care/skincare/ca/p/torriden/dive-in-mild-sunscreen/for/sensitive-skin) — Superior fit — CA$27.34 at Amazon

## Where to buy

No store in Canada has a checked price for this product, so the page shows none.

## Ingredients

Water, Butylene Glycol, Glycerin, 1-Methylhydantoin-2-Imide, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Tocopheryl Acetate, Retinyl Palmitate, Ascorbyl Palmitate, Crithmum Maritimum Extract, Geranium Extract, Mentha Arvensis Leaf Extract, Anthemis Nobilis Flower Extract, Rosa Centifolia Flower Extract, Citrus Aurantium Dulcis Flower Extract, Jasmine Extract, Ferula Galbaniflua Extract Gum, Cananga Odorata Flower Extract, Ribes Nigrum Fruit Extract Black Current Fruit Extract, Propylene Glycol, Hydroxyethylcellulose, Mannitol, Acrylates Vinyl Isodecanoate Crosspolymer, Cellulose, Hydroxypropyl Methylcellulose, Triethyl Citrate, Acrylates Ammonium Methacrylate Copolymer, Polysorbate 20, Carbomer, Triethanolamine, Disodium Edta, Talc, Methylparaben, Dmdm Hydantoin, Mica, Titanium Dioxide, Ultramarines, Red 30
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/mary-kay/timewise-night-solution/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/mary-kay/timewise-night-solution/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/mary-kay/timewise-night-solution/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/mary-kay/timewise-night-solution/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/mary-kay/timewise-night-solution/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/mary-kay/timewise-night-solution/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/mary-kay/timewise-night-solution/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/mary-kay/timewise-night-solution/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/mary-kay/timewise-night-solution/for/sensitive-skin (this page)
- Australia: https://lovi.care/skincare/au/p/mary-kay/timewise-night-solution/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/mary-kay/timewise-night-solution/for/sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/mary-kay/timewise-night-solution/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/mary-kay/timewise-night-solution/for/sensitive-skin