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Lancôme Advanced Génifique Night Cream for combination skin

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes

Lancôme Advanced Génifique Night Cream

Average

  • AverageCombination Skin Fit
  • AverageEffectiveness
  • HighSafety

Works for combination skin; other moisturizers fit it better.

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.

Page built Nov 8, 2026How the Fit score works

Lovi Assistant explains

  • Offers moderate suitability for combination skin, as glycerin and sodium hyaluronate provide excellent hydration and skin barrier support, though it lacks targeted ingredients for your oily shine concern.
  • The formula provides general skincare benefits like soothing and plumping, which you will notice, but these are not directly relevant to managing excess oil.
  • The product is safe for your combination skin with no risks of irritation due to the absence of prohibited or harsh ingredients.

How to apply

  • Use this moisturizer in your AM and PM routine every day to control shine. Always pair with SPF in the morning.
  • Apply this moisturizer after your cleanser and toner, right before your morning SPF.
  • Gently press a small amount of the moisturizer into your skin and avoid harsh rubbing. Let it ⏳absorb for a minute.
  • Apply the moisturizer on slightly damp skin to help it lock in moisture better. This keeps your combination skin balanced.
  • Avoid the eye area when applying the moisturizer. Do a patch test before your first use.

People Say

★4.7Overall rating based on 2.7k+ reviews

Based on a very large amount of data, this product is highly regarded for its ability to deeply hydrate dry and aging skin, effectively repair the moisture barrier, and leave the complexion feeling plump, smooth, and radiant by morning. It is frequently noted for reducing the appearance of fine lines and smoothing the skin texture. While most users find it absorbs quickly without a greasy feel, a small number of individuals with sensitive skin have reported experiencing breakouts or irritation, and some dislike the fragrance.

Highlights

  • Deeply hydrating Mostly Mentioned
    • “The product provides deep hydration and visible rejuvenation.”
    • “Skin feels softer, smoother, and more hydrated.”
    • “Leaves skin moisturized and glowing.”
    • “Thick and moisturizing.”
  • Absorbs quickly Often Mentioned
    • “Doesn't have an oil feeling it's very light.”
    • “Absorbs quickly and leaves skin feeling refreshed without feeling greasy.”
    • “Thicker cream that does not make face feel greasy.”
    • “Does not leave the skin feeling sticky.”
  • Softens and smooths Often Mentioned
    • “Face is so soft, smooth and not puffy.”
    • “Goes on smoothly and makes skin feel like butter.”
    • “Skin feels softer, smoother, and more hydrated.”
    • “Leaves the skin feeling softer, smoother, and more radiant.”
  • Reduces fine lines Sometimes Noted
    • “Helps with wrinkles and makes skin soft.”
    • “Noticed a difference with the crows feet around my eyes.”
    • “Helps reduce the appearance of fine lines and wrinkles.”
    • “Reduces the appearance of fine lines and wrinkles, to leave skin looking youthful.”
  • Causes breakouts Rarely Noted
    • “Caused swelling and breakouts.”
    • “Had a few pimples that I didn't have before.”
    • “Did have one pimple below my eye.”
    • “Tiny pimples (bumps) on my jaw line and above my brows.”
  • Skin irritation Rarely Noted
    • “Started burning my face.”
    • “Smells very bad and itchy.”
    • “Caused swelling and breakouts.”
    • “Afraid to use it because it made me wonder what is in it.”
  • Unpleasant smell Rarely Noted
    • “Smells terrible, similar to hair bleach.”
    • “Smells like old sunscreen.”
    • “Smells very bad.”
    • “Disliked the fragrance.”

Sources: lovi.care, macys.com, lookfantastic.com, ulta.com, lancome-usa.com, nordstromrack.com, and more

Questions and answers

How well does Advanced Génifique Night Cream work for combination skin?

Lancome Advanced Genifique Night Cream works moderately well for combination skin by providing good hydration and skin barrier support, though it lacks targeted ingredients to help manage oily shine. Combination skin of this type needs a formula with effective brightening and moisturizing ingredients that reduce excess oil while keeping skin balanced and calm.

Clinical, Cosmetic and Investigational Dermatology, 2017

Which ingredients make this cream a good fit for combination skin?

Glycerin and sodium hyaluronate make this cream a good fit by providing great hydration and supporting your skin barrier. To work best for combination skin, a product of this type needs ingredients that target oily shine and brighten the skin while keeping it hydrated and calm.

Clinical, Cosmetic and Investigational Dermatology, 2017

What does Bifida Ferment Lysate do for combination skin?

Bifida Ferment Lysate helps strengthen the skin barrier and calm irritation, making it a good fit for combination skin that is prone to sensitivity. This ingredient works by supporting the skin defenses, keeping moisture locked in, and helping to reduce redness.

Journal of Cosmetic Dermatology, 2023Experimental Dermatology, 2010

What does Adenosine do for combination skin?

Adenosine helps smooth out fine lines and keeps combination skin looking firm and well-hydrated. This ingredient is generally well-tolerated and is unlikely to upset either dry or oily areas.

International Journal of Cosmetic Science, 2018International Journal of Molecular Sciences, 2026

Where does this cream go in a skincare routine for combination skin?

This moisturizing treatment goes in the evening routine after cleansing and a cleansing toner, and before your final moisturizer. A product of this type for combination skin needs ingredients that provide hydration and barrier support while also managing oily shine.

Can I use this cream with retinol, and in what order?

You can use this cream with retinol by applying the retinol first, letting it absorb, and then following with this moisturizing treatment. This combination helps keep skin hydrated and is unlikely to cause irritation. Combination skin also needs lightweight, oil-balancing ingredients to manage shine.

Cutis, 2006Clinical, Cosmetic and Investigational Dermatology, 2017

How often should I use this cream?

You can use this moisturizing treatment twice daily as part of your routine. Daily application helps improve skin moisture and supports the skin barrier with a low likelihood of irritation.

Journal of Cosmetic Dermatology, 2020Health Science Reports, 2021

Can this cream clog pores, cause breakouts or purging for combination skin?

This cream is unlikely to clog pores or cause breakouts on combination skin, as it has a very low risk of causing breakouts and is free of harsh ingredients. However, because it lacks targeted ingredients for oily shine, combination skin needs a product that also helps balance excess oil.

Can I use this cream around the eyes or on my body?

You can use this cream around the eyes and on your body, as its formula is safe for skin with no risk of irritation. It provides general hydration and soothing benefits, though combination skin also needs ingredients to manage oily shine.

Surgical and Radiologic Anatomy, 2002Clinical, Cosmetic and Investigational Dermatology, 2017

Is this cream fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (linalool, limonene, citronellol, and parfum). Behenyl alcohol and cetyl alcohol are fatty alcohols, which soften the skin.

What the research says

  • A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

    Clinical, Cosmetic and Investigational Dermatology, 2017

  • Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone.

    Dermatologic Therapy, 2022

  • Emulsions containing ceramides 1 and 3 improved skin hydration and reduced transepidermal water loss in sodium lauryl sulfate-irritated skin of fifteen healthy Asian women compared to a control emulsion.

    International Journal of Dermatology, 2008

  • Topical application of Bifida Ferment Lysate strengthens the skin barrier function by upregulating barrier and antimicrobial peptide genes, exhibiting strong antioxidant properties, and decreasing inflammatory cytokine secretion in vitro.

    Journal of Cosmetic Dermatology, 2023

  • Topical adenosine treatment significantly increased the anagen hair growth rate and thick hair rate compared to placebo in Japanese women with female pattern hair loss over 12 months.

    The Journal of Dermatology, 2008

  • Topical application of a disodium adenosine monophosphate-based formulation reduced wrinkles and hyperpigmentation while improving hydration, barrier function, skin lifting, and epidermal turnover in female participants.

    International Journal of Molecular Sciences, 2026

  • Adenosine and cordycepin stimulate the Wnt/beta-catenin signaling pathway through adenosine receptor and PKA activation, promoting cell proliferation, migration, and growth factor secretion in cultured dermal fibroblasts.

    International Journal of Molecular Sciences, 2021

  • Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

    Journal of Drugs in Dermatology, 2011

  • Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

    Clinical Oral Investigations, 2022

  • Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

    BMC Oral Health, 2019

  • Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers.

    Experimental Dermatology, 2003

  • Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation.

    Journal of Periodontology, 2009

  • Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream.

    Journal of Cosmetic Dermatology, 2022

Ingredients

Water, Bifida Lysate Ferment, Glycerin, Dicaprylyl Ether, Pentylene Glycol, Polyglyceryl-6 Distearate, Propanediol, Cetyl Esters, Jojoba Esters, Ammonium Polyacryloyldimethyl Taurate, Behenyl Alcohol, Octyldodecanol, Acacia Decurrens Flower Cera, Acacia Decurrens Wax Flower, Helianthus Annuus Seed Cera, Sunflower Wax Seed, Helianthus Annuus Seed Oil, Sunflower Seed Oil, Polymnia Sonchifolia Root Juice, Ceramide Np, Alpha-Glucan Oligosaccharide, Sodium Hyaluronate, Sodium Hydroxide, Sodium Stearoyl Glutamate, Salicyloyl Phytosphingosine, 2-Oleamido-1, 3-Octadecanediol, Adenosine, Mannose, Coco-Caprylate Caprate, Ascorbyl Glucoside, Hydroxyacetophenone, Hydroxypalmitoyl Sphinganine, Hydroxypropyl Phosphate Starch, Capryloyl Salicylic Acid, Trisodium Ethylenediamine Disuccinate, Lactic Acid, Lactobacillus, Acetic Acid, Maltodextrin, Yeast Extract, Extrait De Levure, Polyglycerin-3, Polyglyceryl-3 Beeswax, Cetyl Alcohol, Tocopherol, Sodium Benzoate, Linalool, Limonene, Citronellol, Parfum

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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