# La Roche-Posay Toleriane Sensitive Crème for oily acne-prone skin

**Lovi Fit: High fit for oily acne-prone skin.**
Oily Skin Fit: Average · Effectiveness: Average · Safety: Excellent.

Page: https://lovi.care/skincare/ca/p/la-roche-posay/toleriane-sensitive-creme/for/oily-acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Brand: [La Roche-Posay](https://lovi.care/skincare/ca/brands/la-roche-posay)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/ca/best/moisturizers)

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for oily acne-prone skin; a few moisturizers fit it even better.

## Why this fit

- Offers moderate suitability for oily skin as niacinamide helps regulate sebum and hydrate, while glycerin and squalane provide essential moisture and support barrier function. This combination addresses general hydration needs without targeting acne or excessive oiliness.
- The formula is safe for your oily skin, with no harsh ingredients and the inclusion of soothing agents like niacinamide and glycerin to prevent irritation.
- While it provides general skincare benefits, it lacks targeted ingredients like salicylic acid or benzoyl peroxide to effectively manage your acne, blemishes, and breakouts.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ca/p/la-roche-posay/toleriane-sensitive-creme/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/ca/p/la-roche-posay/toleriane-sensitive-creme/for/dry-skin): Superior
- [Combination skin](https://lovi.care/skincare/ca/p/la-roche-posay/toleriane-sensitive-creme/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/ca/p/la-roche-posay/toleriane-sensitive-creme/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/ca/p/la-roche-posay/toleriane-sensitive-creme/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/ca/p/la-roche-posay/toleriane-sensitive-creme/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/ca/p/la-roche-posay/toleriane-sensitive-creme/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/ca/p/la-roche-posay/toleriane-sensitive-creme/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/ca/p/la-roche-posay/toleriane-sensitive-creme/for/oily-acne-prone-skin): High (this page)

## Key ingredients

Thermal Water, Niacinamide, Glycerin, Squalane, Ammonium Polyacryloyldimethyl Taurate

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Balneotherapy with thermal water altered specific skin microbiota at genus and species levels in healthy female volunteers compared to tap water, which produced no significant microbiome changes. ([Life, 2023](https://pubmed.ncbi.nlm.nih.gov/36983902/))
- Malaysian thermal spring water as an adjunct to standard acne therapy improved skin hydration, reduced dryness and stinging, enhanced overall tolerability, and improved the acne disability index in patients with mild to moderate acne. ([The Medical Journal of Malaysia, 2024](https://pubmed.ncbi.nlm.nih.gov/38553920/))
- A 2% Sphingomonas xenophaga ferment extract cream applied twice daily for 4 weeks significantly decreased facial vascular disorder scores compared to vehicle in 86 Caucasian female subjects, alongside dose-dependent inhibition of pre-kallikrein activity in vitro. ([International Journal of Cosmetic Science, 2025](https://pubmed.ncbi.nlm.nih.gov/40545753/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))

## What reviewers say

Users with sensitive, reactive, and combination skin widely praise this moisturizer for its ability to instantly soothe irritation, reduce redness, and alleviate tightness without clogging pores. While the lightweight, fragrance-free formula is celebrated for restoring the skin barrier and sitting well under makeup, some users with extremely dry skin find it insufficiently hydrating, often suggesting the "Riche" version instead.

- Liked: Lightweight texture (mostly mentioned)
- Liked: Gentle & safe (often mentioned)
- Liked: Soothing and calming (often mentioned)
- Disliked: Price vs. quantity (often mentioned)
- Liked: Restores skin barrier (sometimes noted)
- Disliked: Not moisturizing enough (sometimes noted)
- Disliked: Breakouts/reactions (rarely noted)
- Disliked: Packaging issues (rarely noted)

## How to apply

- Use this AM and PM routine every day to help clear your skin. Always remember to finish with SPF in the morning.
- Apply the moisturizer after your cleanser and toner, right before your SPF during the day.
- Gently press a small amount into your skin and avoid rubbing to keep pores clear.
- Apply on clean, slightly damp skin to help the product absorb better and control oil.
- Avoid the sensitive eye area and do a simple patch test before your first use.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes La Roche-Posay Toleriane Sensitive Crème a great fit for oily acne-prone skin?

La Roche-Posay Toleriane Sensitive Crème is a great fit because niacinamide helps regulate oil while glycerin and squalane provide essential moisture without feeling heavy. Its gentle formula is safe and soothing for your skin, though it lacks targeted acne-fighting ingredients like salicylic acid.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this cream a good fit for oily acne-prone skin?

Niacinamide, glycerin, and squalane make this cream a good fit by helping regulate oil, hydrate, and support the skin barrier without harsh ingredients. Niacinamide and glycerin may also soothe the skin to help prevent irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Thermal Water do for oily acne-prone skin?

Thermal water helps calm oily, acne-prone skin by reducing dryness, stinging, and redness while improving overall skin comfort. It is useful as an extra step in your routine because it supports hydration and makes acne treatments more gentle on the skin.
Sources: [The Medical Journal of Malaysia, 2024](https://pubmed.ncbi.nlm.nih.gov/38553920/), [Journal of Cosmetic Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17348993/)

### What does Niacinamide do for oily acne-prone skin?

Niacinamide helps balance oil production, calms redness, and is unlikely to irritate oily, acne-prone skin while improving blemishes. Clinical tests show it reduces excess oil and helps clear up both inflammatory and non-inflammatory acne breakouts.
Sources: [Journal of Cosmetic and Laser Therapy, 2006](https://pubmed.ncbi.nlm.nih.gov/16766489/), [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38299457/)

### Where does this cream go in a skincare routine for oily acne-prone skin?

This cream goes in the morning routine after your hydrating toner and before your sunscreen, and in the evening routine as your final step after any treatment. It is a great fit for your skin, as niacinamide helps balance oil while glycerin and squalane provide gentle moisture without clogging pores.
Sources: [International Journal of Cosmetic Science, 2020](https://pubmed.ncbi.nlm.nih.gov/31461548/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use this cream with retinol, and in what order?

You can use this cream with retinol by applying it either before or after your retinol treatment to help keep your skin calm and moisturized. Using a gentle moisturizer with ingredients like glycerin and squalane is unlikely to interfere with your treatment and may help reduce dryness or irritation.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [The Journal of Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/24930436/)

### How often should I use this cream?

You can use this cream daily in your morning and evening routines to keep your skin hydrated and calm. Consistent daily application helps maintain your skin barrier without clogging pores.
Sources: [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can this cream clog pores, cause breakouts or purging for oily acne-prone skin?

This cream is unlikely to cause breakouts or clog pores on oily acne-prone skin because it has a safe formula with no harsh ingredients and includes soothing agents like niacinamide and glycerin to prevent irritation. However, it lacks targeted blemish-fighting ingredients like salicylic acid or benzoyl peroxide to actively manage acne.

### Can I use this cream around the eyes or on my body?

You can use this cream safely on your body and around your eyes, as it is gentle and has a very good safety profile. However, because skin thickness varies across the body, the thin skin around your eyes and thicker skin on your body may absorb moisture and active ingredients differently.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/)

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for oily acne-prone skin

- [COSRX Advanced Snail 96 Mucin Power Essence](https://lovi.care/skincare/ca/p/cosrx/advanced-snail-96-mucin-power-essence/for/oily-acne-prone-skin) — Superior fit — CA$24.99 at Amazon
- [Drunk Elephant Protini Polypeptide Cream](https://lovi.care/skincare/ca/p/drunk-elephant/protini-polypeptide-cream/for/oily-acne-prone-skin) — High fit — CA$95.99 at Amazon
- [belif The True Cream Aqua Bomb](https://lovi.care/skincare/ca/p/belif/the-true-cream-aqua-bomb/for/oily-acne-prone-skin) — High fit — CA$49.99 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/ca/p/cerave/foaming-facial-cleanser/for/oily-acne-prone-skin) — Superior fit — CA$20.96 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/ca/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-acne-prone-skin) — Superior fit — CA$37.60 at Amazon
- SPF: [CeraVe AM Facial Moisturizing Lotion](https://lovi.care/skincare/ca/p/cerave/am-facial-moisturizing-lotion-spf-30/for/oily-acne-prone-skin) — Superior fit — CA$20.96 at Amazon

## Where to buy

- Amazon.ca: CA$31.00 (https://www.amazon.ca/dp/B07942ZQBT?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- Shoppers Drug Mart: CA$31.00 (https://www.shoppersdrugmart.ca/la-roche-posay-toleriane-sensitive/p/BB_3337875578486?variantCode=3337875578486)
Prices checked 2 Nov – 6 Nov 2026.

## Ingredients

Water, Glycerin, Caprylic Capric Triglyceride, Propanediol, Pentylene Glycol, Niacinamide, Ammonium Polyacryloyldimethyl Taurate, Caprylyl Glycol, Citric Acid, Xanthan Gum, Squalane, Dimethicone, Zea Mays Corn Starch, Ceramide Np, Myristyl Myristate, Stearic Acid, Palmitic Acid, Capryloyl Glycine, Potassium Cetyl Phosphate, Sodium Hydroxide, Myristic Acid
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/la-roche-posay/toleriane-sensitive-creme/for/oily-acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/la-roche-posay/toleriane-sensitive-creme/for/oily-acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/la-roche-posay/toleriane-sensitive-creme/for/oily-acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/la-roche-posay/toleriane-sensitive-creme/for/oily-acne-prone-skin
- France: https://lovi.care/skincare/fr/p/la-roche-posay/toleriane-sensitive-creme/for/oily-acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/la-roche-posay/toleriane-sensitive-creme/for/oily-acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/la-roche-posay/toleriane-sensitive-creme/for/oily-acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/la-roche-posay/toleriane-sensitive-creme/for/oily-acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/la-roche-posay/toleriane-sensitive-creme/for/oily-acne-prone-skin (this page)
- Australia: https://lovi.care/skincare/au/p/la-roche-posay/toleriane-sensitive-creme/for/oily-acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/la-roche-posay/toleriane-sensitive-creme/for/oily-acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/la-roche-posay/toleriane-sensitive-creme/for/oily-acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/la-roche-posay/toleriane-sensitive-creme/for/oily-acne-prone-skin