# La Roche-Posay Toleriane Dermallergo Night for oily acne-prone skin

**Lovi Fit: High fit for oily acne-prone skin.**
Oily Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/ca/p/la-roche-posay/toleriane-dermallergo-night/for/oily-acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Brand: [La Roche-Posay](https://lovi.care/skincare/ca/brands/la-roche-posay)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/ca/best/moisturizers)

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for oily acne-prone skin; a few moisturizers fit it even better.

## Why this fit

- Offers high suitability for your oily skin due to niacinamide and squalane, which help regulate sebum production and provide emollient action, addressing your concerns with oiliness and breakouts.
- The formula provides excellent moisturizing benefits with squalane and glycerin, enhancing barrier resilience and hydration for your skin.
- The safety profile is excellent, with no risks of irritation for your oily skin due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ca/p/la-roche-posay/toleriane-dermallergo-night/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/ca/p/la-roche-posay/toleriane-dermallergo-night/for/dry-skin): Superior
- [Combination skin](https://lovi.care/skincare/ca/p/la-roche-posay/toleriane-dermallergo-night/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/ca/p/la-roche-posay/toleriane-dermallergo-night/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/ca/p/la-roche-posay/toleriane-dermallergo-night/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/ca/p/la-roche-posay/toleriane-dermallergo-night/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/ca/p/la-roche-posay/toleriane-dermallergo-night/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/ca/p/la-roche-posay/toleriane-dermallergo-night/for/dry-sensitive-skin): Superior
- [Oily acne-prone skin](https://lovi.care/skincare/ca/p/la-roche-posay/toleriane-dermallergo-night/for/oily-acne-prone-skin): High (this page)

## Key ingredients

Thermal Spring Water, Squalane, Niacinamide, Butyrospermum Parkii Shea Butter, Dimethicone

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Malaysian thermal spring water as an adjunct to standard acne therapy improved skin hydration, reduced dryness and stinging, enhanced overall tolerability, and improved the acne disability index in patients with mild to moderate acne. ([The Medical Journal of Malaysia, 2024](https://pubmed.ncbi.nlm.nih.gov/38553920/))
- Avène Thermal Spring Water significantly decreased postpeeling redness and reduced the overall sensitive scale of consumers by 47% compared to mineral-rich thermal spring water in human volunteers. ([Journal of the European Academy of Dermatology and Venereology, 2020](https://pubmed.ncbi.nlm.nih.gov/32870553/))
- Balneotherapy with thermal water altered specific skin microbiota at genus and species levels in healthy female volunteers compared to tap water, which produced no significant microbiome changes. ([Life, 2023](https://pubmed.ncbi.nlm.nih.gov/36983902/))
- A 2% Sphingomonas xenophaga ferment extract cream applied twice daily for 4 weeks significantly decreased facial vascular disorder scores compared to vehicle in 86 Caucasian female subjects, alongside dose-dependent inhibition of pre-kallikrein activity in vitro. ([International Journal of Cosmetic Science, 2025](https://pubmed.ncbi.nlm.nih.gov/40545753/))
- A formulation containing vitamin C, biopeptides, hyaluronic acid, and mineralizing water accelerated cell turnover to 17.1 days versus 19.2 days for untreated skin, and reduced crow's-feet, forehead, and nasolabial folds by 9%, 11%, and 5% respectively after 28 days in female subjects. ([International Journal of Cosmetic Science, 2021](https://pubmed.ncbi.nlm.nih.gov/33038010/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- A combination cream of stimu-tex AS and saccharide isomerate reduced erythema, increased skin capacitance, and reduced transepidermal water loss compared to placebo in 20 subjects after fractional CO2 laser procedure without causing serious adverse events. ([Lasers in Medical Science, 2025](https://pubmed.ncbi.nlm.nih.gov/41134387/))
- A skin barrier restoring cream with shea butter, silkflo, and vitamin E increased type I procollagen synthesis, enhanced antioxidant enzyme activity, decreased reactive oxygen species generation, and promoted hyaluronic acid production in H2O2-stimulated human keratinocyte cells compared to untreated cells. ([International Journal of Cosmetic Science, 2025](https://pubmed.ncbi.nlm.nih.gov/39528438/))
- Wearing an N95 mask alone compared to using dimethicone cream or hydrocolloid dressing caused more adverse skin reactions among 73 military health care workers, with no significant differences in fit test failure rates between groups. ([Military Medicine, 2024](https://pubmed.ncbi.nlm.nih.gov/38771104/))
- Treatment with a moisturizer containing dimethicone and glycerine increased epidermal thickness by 0.019 mm, improved barrier function by decreasing transepidermal water loss by 13%, decreased melanin intensity, and induced keratins 6 and 16 in fifteen women with moderately photoaged forearms. ([Clinical and Experimental Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17137484/))

## What reviewers say

Users frequently report waking up to softer, plumper, and less irritated skin. A minority of users with oily or acne-prone skin found the formula too heavy or experienced breakouts.

- Liked: Soothes sensitive skin (mostly mentioned)
- Liked: Deeply hydrating (often mentioned)
- Liked: Lightweight texture (sometimes noted)
- Disliked: Causes breakouts (rarely noted)
- Disliked: Not hydrating enough (rarely noted)
- Disliked: Sticky or heavy (rarely noted)

## How to apply

- Use this AM and PM routine every day to help clear your skin. Always remember to finish with SPF in the morning.
- Apply the moisturizer after your cleanser and toner, right before your SPF during the day.
- Gently press a small amount into your skin and avoid rubbing to keep pores clear.
- Apply on clean, slightly damp skin to help the product absorb better and control oil.
- Avoid the sensitive eye area and do a simple patch test before your first use.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes La Roche-Posay Toleriane Dermallergo Night a great fit for oily acne-prone skin?

La Roche-Posay Toleriane Dermallergo Night is a great fit for oily acne-prone skin because niacinamide and squalane help manage oil and breakouts while keeping skin soft. The formula also provides great moisture with glycerin and squalane to support a healthy skin barrier without any harsh risks of irritation.

### Which ingredients make this cream a good fit for oily acne-prone skin?

This cream is a great fit for your oily skin because it contains niacinamide and squalane, which help regulate oil and soothe breakouts. The formula also includes glycerin and thermal spring water to boost hydration without irritation.
Sources: [The Medical Journal of Malaysia, 2024](https://pubmed.ncbi.nlm.nih.gov/38553920/)

### What does Thermal Spring Water do for oily acne-prone skin?

Thermal spring water helps calm oily, acne-prone skin by reducing redness, dryness, and stinging while improving overall skin comfort. It is well tolerated and may enhance the effects of your standard acne routine.
Sources: [Journal of the European Academy of Dermatology and Venereology, 2020](https://pubmed.ncbi.nlm.nih.gov/32870553/), [The Medical Journal of Malaysia, 2024](https://pubmed.ncbi.nlm.nih.gov/38553920/)

### What does Squalane do for oily acne-prone skin?

Squalane may help keep oily skin soft and smooth, but oxidized squalene can trigger inflammation in acne-prone skin. Because of this, oily acne-prone skin needs lightweight, non-greasy ingredients that balance moisture without clogging pores.
Sources: [The Journal of Investigative Dermatology, 2006](https://pubmed.ncbi.nlm.nih.gov/16778793/)

### Where does this cream go in a skincare routine for oily acne-prone skin?

This moisturizer goes as the final step of your morning routine and evening routine. It helps keep your skin balanced and hydrated without causing irritation.
Sources: [International Journal of Cosmetic Science, 2020](https://pubmed.ncbi.nlm.nih.gov/31461548/), [The Medical Journal of Malaysia, 2024](https://pubmed.ncbi.nlm.nih.gov/38553920/)

### Can I use this cream with retinol, and in what order?

Yes, you can use this moisturizer with retinol, and applying it after your retinol treatment helps calm your skin and keep it comfortable. Using a gentle moisturizer alongside strong acne treatments like retinol is unlikely to cause irritation and may improve how well your skin handles the routine.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [The Journal of Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/24930436/)

### How often should I use this cream?

You can use this moisturizer daily as part of your evening routine. Regular application helps keep your skin hydrated and balanced without causing irritation.
Sources: [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/), [Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/14571069/)

### Can this cream clog pores, cause breakouts or purging for oily acne-prone skin?

This cream is a great fit for oily acne-prone skin and is unlikely to cause breakouts, as its ingredients help balance oil and soothe the skin without harsh additives. Reviewers rarely report breakouts, and its safety profile shows no risk of irritation.
Sources: [The Medical Journal of Malaysia, 2024](https://pubmed.ncbi.nlm.nih.gov/38553920/)

### Can I use this cream around the eyes or on my body?

You can use this moisturizer around your eyes, where the skin is particularly thin, as well as on your body. Its safe and gentle ingredients are well-tolerated and unlikely to cause irritation in delicate areas.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/)

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for oily acne-prone skin

- [COSRX Advanced Snail 96 Mucin Power Essence](https://lovi.care/skincare/ca/p/cosrx/advanced-snail-96-mucin-power-essence/for/oily-acne-prone-skin) — Superior fit — CA$24.99 at Amazon
- [Drunk Elephant Protini Polypeptide Cream](https://lovi.care/skincare/ca/p/drunk-elephant/protini-polypeptide-cream/for/oily-acne-prone-skin) — High fit — CA$95.99 at Amazon
- [belif The True Cream Aqua Bomb](https://lovi.care/skincare/ca/p/belif/the-true-cream-aqua-bomb/for/oily-acne-prone-skin) — High fit — CA$49.99 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/ca/p/cerave/foaming-facial-cleanser/for/oily-acne-prone-skin) — Superior fit — CA$20.96 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/ca/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-acne-prone-skin) — Superior fit — CA$37.60 at Amazon
- SPF: [CeraVe AM Facial Moisturizing Lotion](https://lovi.care/skincare/ca/p/cerave/am-facial-moisturizing-lotion-spf-30/for/oily-acne-prone-skin) — Superior fit — CA$20.96 at Amazon

## Where to buy

- Amazon.ca: CA$41.00 (https://www.amazon.ca/dp/B09XJWJM44?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- Shoppers Drug Mart: CA$41.00 (https://www.shoppersdrugmart.ca/la-roche-posay-toleriane-dermallergo-overnight-soothing-facial-mo/p/BB_3337875800853?variantCode=3337875800853)
Prices checked 25 Oct – 2 Nov 2026.

## Ingredients

Water, Squalane, Butyrospermum Parkii Shea Butter, Glycerin, Dimethicone, Pentylene Glycol, Niacinamide, Sodium Hydroxide, Tocopherol, Adenosine, Caprylyl Glycol, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Citric Acid, Disodium Edta, Ethylhexylglycerin, Sodium Citrate, Xanthan Gum, Polysorbate 20
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/la-roche-posay/toleriane-dermallergo-night/for/oily-acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/la-roche-posay/toleriane-dermallergo-night/for/oily-acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/la-roche-posay/toleriane-dermallergo-night/for/oily-acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/la-roche-posay/toleriane-dermallergo-night/for/oily-acne-prone-skin
- France: https://lovi.care/skincare/fr/p/la-roche-posay/toleriane-dermallergo-night/for/oily-acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/la-roche-posay/toleriane-dermallergo-night/for/oily-acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/la-roche-posay/toleriane-dermallergo-night/for/oily-acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/la-roche-posay/toleriane-dermallergo-night/for/oily-acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/la-roche-posay/toleriane-dermallergo-night/for/oily-acne-prone-skin (this page)
- Australia: https://lovi.care/skincare/au/p/la-roche-posay/toleriane-dermallergo-night/for/oily-acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/la-roche-posay/toleriane-dermallergo-night/for/oily-acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/la-roche-posay/toleriane-dermallergo-night/for/oily-acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/la-roche-posay/toleriane-dermallergo-night/for/oily-acne-prone-skin