# La Roche-Posay Toleriane Dermallergo Crème for combination skin

**Lovi Fit: Average fit for combination skin.**
Combination Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/ca/p/la-roche-posay/toleriane-dermallergo-creme/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Brand: [La Roche-Posay](https://lovi.care/skincare/ca/brands/la-roche-posay)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/ca/best/moisturizers)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for combination skin; other moisturizers fit it better.

## Why this fit

- Offers moderate moisturizing for your combination skin, as glycerin and hyaluronic acid provide hydration and plumpness, though it lacks targeted ingredients to address oily shine.
- Niacinamide and squalane offer additional soothing and emollient benefits, supporting overall skin comfort.
- The product is safe for your combination skin, with no risks of irritation due to the absence of harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ca/p/la-roche-posay/toleriane-dermallergo-creme/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/ca/p/la-roche-posay/toleriane-dermallergo-creme/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/ca/p/la-roche-posay/toleriane-dermallergo-creme/for/combination-skin): Average (this page)
- [Sensitive skin](https://lovi.care/skincare/ca/p/la-roche-posay/toleriane-dermallergo-creme/for/sensitive-skin): Superior
- [Acne-prone skin](https://lovi.care/skincare/ca/p/la-roche-posay/toleriane-dermallergo-creme/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/ca/p/la-roche-posay/toleriane-dermallergo-creme/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/ca/p/la-roche-posay/toleriane-dermallergo-creme/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/ca/p/la-roche-posay/toleriane-dermallergo-creme/for/dry-sensitive-skin): Superior
- [Oily acne-prone skin](https://lovi.care/skincare/ca/p/la-roche-posay/toleriane-dermallergo-creme/for/oily-acne-prone-skin): Average

## Key ingredients

Glycerin, Squalane, Niacinamide, Butyrospermum Parkii Butter Shea Butter, Hyaluronic Acid

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Treatment with a combination of niacinamide and hyaluronic acid improved skin aging signs and demonstrated a senomorphic effect by decreasing SASP and autocrine signaling genes in women. ([Scientific Reports, 2024](https://pubmed.ncbi.nlm.nih.gov/39009698/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical 2% niacinamide significantly decreased sebum excretion rate in Japanese individuals and casual sebum levels in Caucasian individuals compared to placebo or baseline. ([Journal of Cosmetic and Laser Therapy, 2006](https://pubmed.ncbi.nlm.nih.gov/16766489/))
- A combination cream of stimu-tex AS and saccharide isomerate reduced erythema, increased skin capacitance, and reduced transepidermal water loss compared to placebo in 20 subjects after fractional CO2 laser procedure without causing serious adverse events. ([Lasers in Medical Science, 2025](https://pubmed.ncbi.nlm.nih.gov/41134387/))
- A skin barrier restoring cream with shea butter, silkflo, and vitamin E increased type I procollagen synthesis, enhanced antioxidant enzyme activity, decreased reactive oxygen species generation, and promoted hyaluronic acid production in H2O2-stimulated human keratinocyte cells compared to untreated cells. ([International Journal of Cosmetic Science, 2025](https://pubmed.ncbi.nlm.nih.gov/39528438/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))

## What reviewers say

Users with dry, ultra-sensitive, and allergy-prone skin frequently praise this product for its deep hydration and immediate soothing of redness and irritation. It is also often noted as being safe for sensitive skin and absorbing quickly. Some users find the quantity to be small for the price and the packaging can be frustrating to empty completely.

- Liked: Calms redness (mostly mentioned)
- Liked: Deeply hydrating (often mentioned)
- Liked: Safe for sensitive skin (often mentioned)
- Liked: Absorbs quickly (sometimes noted)
- Disliked: Expensive for quantity (sometimes noted)
- Disliked: Can feel drying (rarely noted)
- Disliked: Causes pilling (rarely noted)
- Disliked: Frustrating packaging (rarely noted)

## How to apply

- Use this moisturizer in your AM and PM routine every day to control shine. Always pair with SPF in the morning.
- Apply this moisturizer after your cleanser and toner, right before your morning SPF.
- Gently press a small amount of the moisturizer into your skin and avoid harsh rubbing. Let it ⏳absorb for a minute.
- Apply the moisturizer on slightly damp skin to help it lock in moisture better. This keeps your combination skin balanced.
- Avoid the eye area when applying the moisturizer. Do a patch test before your first use.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does La Roche-Posay Toleriane Dermallergo Crème work for combination skin?

La Roche-Posay Toleriane Dermallergo Crème works moderately well for combination skin because glycerin and hyaluronic acid provide hydration and plumpness, though it lacks targeted ingredients to address oily shine. Niacinamide and squalane help soothe the skin and maintain comfort safely without causing irritation. A moisturizer for this skin type needs effective brightening and hydrating ingredients that reduce oily shine while keeping the skin balanced.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this cream a good fit for combination skin?

Glycerin and hyaluronic acid make this cream a good fit by giving your combination skin moderate moisture and plumpness, while niacinamide and squalane help keep it comfortable and smooth. Because it lacks ingredients to handle oily shine, a product of this type needs brightening and oil-balancing ingredients to be a top fit for this skin.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Glycerin do for combination skin?

Glycerin helps keep combination skin soft and smooth by pulling moisture in and keeping it there. It improves hydration and supports your skin barrier, which is unlikely to cause irritation.
Sources: [The British Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18510666/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Squalane do for combination skin?

Squalane helps keep combination skin soft and smooth by locking in moisture without feeling heavy or greasy. It supports the skin barrier and provides lightweight hydration that works well for both dry and oily areas.
Sources: [Skin Health and Disease, 2024](https://pubmed.ncbi.nlm.nih.gov/39355739/), [Journal of Nanobiotechnology, 2025](https://pubmed.ncbi.nlm.nih.gov/40001122/)

### Where does this cream go in a skincare routine for combination skin?

This moisturizer goes as the third step in your morning routine after a cleanser and hydrating toner, and as the final step in your evening routine. Combination skin of this type needs a moisturizer that balances hydration with oil-controlling ingredients to keep the T-zone from getting shiny.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use this cream with retinol, and in what order?

You can use this cream with retinol, applying it after your retinol treatment to help soothe your skin and keep it comfortable. A moisturizer for combination skin also needs ingredients that help balance oily shine.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use this cream?

You can use this cream twice a day as part of your morning and evening routine to keep your skin hydrated and comfortable. Daily application helps maintain moisture and supports your skin barrier without causing irritation.
Sources: [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/), [Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/14571069/)

### Can this cream clog pores, cause breakouts or purging for combination skin?

This cream is unlikely to clog pores or cause breakouts for combination skin, as it has a safe profile with no harsh ingredients that typically cause irritation. However, because it works as an average fit, combination skin sometimes needs lighter hydration along with ingredients that control oily shine in the t-zone.

### Can I use this cream around the eyes or on my body?

You can use this moisturizer around your eyes and on your body, as its gentle ingredients are safe for delicate skin. However, combination skin often needs a lightweight product with oil-controlling ingredients for the face, and a richer cream to keep dry body areas soft and smooth.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/)

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for combination skin

- [Drunk Elephant Protini Polypeptide Cream](https://lovi.care/skincare/ca/p/drunk-elephant/protini-polypeptide-cream/for/combination-skin) — Superior fit — CA$95.99 at Amazon
- [The Ordinary Natural Moisturizing Factors + HA](https://lovi.care/skincare/ca/p/the-ordinary/natural-moisturizing-factors-ha/for/combination-skin) — High fit — CA$16.20 at Amazon
- [ANUA Heartleaf 70% Soothing Cream](https://lovi.care/skincare/ca/p/anua/heartleaf-70-soothing-cream/for/combination-skin) — High fit — CA$40.53 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/ca/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — CA$44.95 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/ca/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — CA$37.60 at Amazon
- SPF: [CeraVe AM Facial Moisturizing Lotion](https://lovi.care/skincare/ca/p/cerave/am-facial-moisturizing-lotion-spf-30/for/combination-skin) — Superior fit — CA$20.96 at Amazon

## Where to buy

- Amazon.ca: CA$34.85 (https://www.amazon.ca/dp/B09DPGJC3B?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
Prices checked 3 Nov 2026.

## Ingredients

Water, Glycerin, Squalane, Pentylene Glycol, Butylene Glycol, Propanediol, Dimethicone, Niacinamide, Butyrospermum Parkii Shea Butter, Hyaluronic Acid, Polysorbate 20, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Caprylyl Glycol, Citric Acid, Tocopherol, Ethylhexylglycerin, Sodium Hydroxide
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/la-roche-posay/toleriane-dermallergo-creme/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/la-roche-posay/toleriane-dermallergo-creme/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/la-roche-posay/toleriane-dermallergo-creme/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/la-roche-posay/toleriane-dermallergo-creme/for/combination-skin
- France: https://lovi.care/skincare/fr/p/la-roche-posay/toleriane-dermallergo-creme/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/la-roche-posay/toleriane-dermallergo-creme/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/la-roche-posay/toleriane-dermallergo-creme/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/la-roche-posay/toleriane-dermallergo-creme/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/la-roche-posay/toleriane-dermallergo-creme/for/combination-skin (this page)
- Australia: https://lovi.care/skincare/au/p/la-roche-posay/toleriane-dermallergo-creme/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/la-roche-posay/toleriane-dermallergo-creme/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/la-roche-posay/toleriane-dermallergo-creme/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/la-roche-posay/toleriane-dermallergo-creme/for/combination-skin