# La Roche-Posay Cicaplast Gel B5 for sensitive skin

**Lovi Fit: Superior fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/ca/p/la-roche-posay/cicaplast-gel-b5/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Brand: [La Roche-Posay](https://lovi.care/skincare/ca/brands/la-roche-posay)
Category: [Serums and treatments](https://lovi.care/skincare/ca/best/serums)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best serums for sensitive skin.

## Why this fit

- Excellent for your normal skin with sensitivity, this product leverages Panthenol and Madecassoside to effectively soothe redness and irritation while enhancing skin barrier resilience.
- The inclusion of Sodium Hyaluronate further supports hydration, making it highly suitable for maintaining comfortable and balanced skin.
- The safety profile is excellent, with no risks of irritation due to the absence of harsh ingredients and the presence of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ca/p/la-roche-posay/cicaplast-gel-b5/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/ca/p/la-roche-posay/cicaplast-gel-b5/for/dry-skin): Superior
- [Combination skin](https://lovi.care/skincare/ca/p/la-roche-posay/cicaplast-gel-b5/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/ca/p/la-roche-posay/cicaplast-gel-b5/for/sensitive-skin): Superior (this page)
- [Acne-prone skin](https://lovi.care/skincare/ca/p/la-roche-posay/cicaplast-gel-b5/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/ca/p/la-roche-posay/cicaplast-gel-b5/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/ca/p/la-roche-posay/cicaplast-gel-b5/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/ca/p/la-roche-posay/cicaplast-gel-b5/for/dry-sensitive-skin): Superior
- [Oily acne-prone skin](https://lovi.care/skincare/ca/p/la-roche-posay/cicaplast-gel-b5/for/oily-acne-prone-skin): High

## Key ingredients

Panthenol B5, Glycerin, Madecassoside, Zinc Gluconate, Sodium Hyaluronate

## What the research says

- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/))
- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Panthenyl triacetate (PTA) demonstrated skin de-acetylation into panthenol, stimulated energetic and synthesis metabolic pathways, and achieved a statistically significant improvement in wound healing after 72 hours compared to saline treatment in human volunteers, outperforming panthenol in long-lasting wound healing action. ([Journal of Cosmetic Science, 2012](https://pubmed.ncbi.nlm.nih.gov/22487447/))
- A comprehensive topical regimen incorporating niacinamide, Pro-Xylane, and panthenol following PicoWay laser treatment decreased transepidermal water loss, increased hydration and skin elasticity, reduced wrinkles and redness, and improved skin tone in 88 Chinese females compared to a standard care control group. ([Lasers in Medical Science, 2026](https://pubmed.ncbi.nlm.nih.gov/42686896/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Treatment with an asiaticoside-containing cream applied twice daily for 12 weeks significantly improved periorbital wrinkles in 65% of 27 female volunteers compared to a vehicle control cream. ([International Journal of Cosmetic Science, 2008](https://pubmed.ncbi.nlm.nih.gov/18452433/))
- A dermocosmetic cream containing Punica granatum Pericarp extract, Salicylic acid, Niacinamide, Zinc gluconate, and Aqua Posae Filiformis significantly decreased inflammatory, non-inflammatory, and total lesion counts in subjects with mild to moderate acne compared to untreated hemi-faces after 15 days. ([Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41487026/))
- Daily use of a deep cleansing gel containing salicylic acid 2%, zinc gluconate 0.2% and lipohydroxy acid 0.05% significantly reduced total lesion count by 56.3% after 84 days in 35 subjects with mild to moderate truncal acne. ([Clinical, Cosmetic and Investigational Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/36698447/))
- Different strains of Propionibacterium acnes modulate cutaneous innate immunity with varying pro-inflammatory potentials, with P. acnes type III showing the highest and P. avidum the weakest, and zinc gluconate down-regulates the expression of most induced immune markers. ([Experimental Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23947673/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))

## What reviewers say

Users find this gel to be a lightweight, non-greasy option for repairing skin barriers, particularly beneficial for oily or acne-prone skin. It is highly effective for healing post-procedure skin, soothing irritation from treatments like retinoids, and protecting compromised skin. Some users note a shiny finish that may not be ideal for daytime wear.

- Liked: Accelerates healing (mostly mentioned)
- Liked: Lightweight & non-greasy (often mentioned)
- Liked: Soothing & calming (often mentioned)
- Liked: Safe for acne-prone (sometimes noted)
- Disliked: Shiny/tacky finish (sometimes noted)
- Disliked: Small size/price (sometimes noted)
- Disliked: Makeup incompatibility (rarely noted)
- Disliked: Not moisturizing enough (rarely noted)

## How to apply

- Use your serum in the PM routine, starting 3 times a week before building up to daily use if your skin is happy.
- Apply the serum after cleansing and toning, but before putting on your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏱ for it to soak in.
- Since your skin is sensitive and easily irritated, apply the serum on completely dry skin to help keep it calm.
- Always do a patch test before your first use and avoid getting the serum too close to your eyes .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes La Roche-Posay Cicaplast Gel B5 one of the best fits for sensitive skin?

La Roche-Posay Cicaplast Gel B5 is one of the best fits for sensitive skin because it uses panthenol and madecassoside to calm redness and irritation while helping the skin barrier stay strong. Sodium Hyaluronate adds hydration to keep the skin feeling comfortable and balanced, and the gentle formula is very unlikely to cause any irritation.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### Which ingredients make this treatment a good fit for sensitive skin?

Panthenol and madecassoside make this treatment a great fit because they help soothe redness and irritation while strengthening the skin barrier. Sodium Hyaluronate also supports hydration to keep sensitive skin comfortable and balanced, with a very low risk of irritation.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### What does Panthenol do for sensitive skin?

Panthenol helps calm sensitive skin by reducing redness and irritation while improving hydration and repairing the skin barrier. It is unlikely to cause negative reactions and supports healing for dry or reactive skin.
Sources: [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40682399/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### What does Glycerin do for sensitive skin?

Glycerin helps keep sensitive skin soft and deeply hydrated while supporting the skin barrier. It is unlikely to cause irritation and may protect against dryness and roughness.
Sources: [The British Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18510666/), [Acta Dermato-venereologica, 1999](https://pubmed.ncbi.nlm.nih.gov/10598752/)

### Where does this treatment go in a skincare routine for sensitive skin?

This treatment goes in the evening routine after cleansing and toning, and before moisturizing. It is formulated with panthenol and madecassoside to soothe redness and irritation while supporting your skin barrier, and its safety profile is excellent with no risks of irritation.

### Can I use it with retinol, and in what order?

Yes, you can use La Roche-Posay Cicaplast Gel B5 with retinol by applying the treatment after your retinol to help calm irritation and keep your skin comfortable. This type of soothing combination helps maintain your skin barrier resilience and is unlikely to cause irritation.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### How often should I use this treatment?

This treatment fits into your evening routine as an extra step, and you can safely use it every day to help keep your skin calm and comfortable. It is unlikely to cause any irritation because it leaves out harsh ingredients and uses soothing components like Panthenol and Madecassoside.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Can it clog pores, cause breakouts or purging for sensitive skin?

This product is unlikely to clog pores or cause breakouts for sensitive skin because it avoids harsh ingredients and features soothing components that help keep the skin calm and balanced.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Is this treatment fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for sensitive skin

- [Clarins Double Serum](https://lovi.care/skincare/ca/p/clarins/double-serum/for/sensitive-skin) — High fit — CA$113.00 at Amazon
- [COSRX The Vitamin C 23 Serum](https://lovi.care/skincare/ca/p/cosrx/the-vitamin-c-23-serum/for/sensitive-skin) — High fit — CA$33.98 at Amazon
- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/ca/p/skin1004/probio-cica-intensive-ampoule/for/sensitive-skin) — High fit — CA$24.44 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/ca/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — CA$44.95 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/ca/p/clarins/soothing-toning-lotion/for/sensitive-skin) — Superior fit — CA$49.00 at Amazon
- Moisturizer with Sun Protection: [Torriden DIVE-IN Mild Sunscreen](https://lovi.care/skincare/ca/p/torriden/dive-in-mild-sunscreen/for/sensitive-skin) — Superior fit — CA$27.34 at Amazon

## Where to buy

- Amazon.ca: CA$26.00 (https://www.amazon.ca/dp/B077YNHBSL?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- Shoppers Drug Mart: CA$26.00 (https://www.shoppersdrugmart.ca/la-roche-posay-cicaplast-gel-b5/p/BB_3337875586269?variantCode=3337875586269)
Prices checked 10 Oct – 6 Nov 2026.

## Ingredients

Water, Glycerin, Dimethicone, Panthenol, Pentylene Glycol, C30-45 Alkyl Dimethicone, Polybutene, Sodium Citrate, Peg Ppg-18 18 Dimethicone, Zinc Gluconate, Madecassoside, Dimethiconol, Manganese Gluconate, Sodium Hyaluronate, Copper Gluconate, Caprylyl Glycol, Citric Acid, Polysorbate 20, Tocopherol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/la-roche-posay/cicaplast-gel-b5/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/la-roche-posay/cicaplast-gel-b5/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/la-roche-posay/cicaplast-gel-b5/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/la-roche-posay/cicaplast-gel-b5/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/la-roche-posay/cicaplast-gel-b5/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/la-roche-posay/cicaplast-gel-b5/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/la-roche-posay/cicaplast-gel-b5/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/la-roche-posay/cicaplast-gel-b5/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/la-roche-posay/cicaplast-gel-b5/for/sensitive-skin (this page)
- Australia: https://lovi.care/skincare/au/p/la-roche-posay/cicaplast-gel-b5/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/la-roche-posay/cicaplast-gel-b5/for/sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/la-roche-posay/cicaplast-gel-b5/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/la-roche-posay/cicaplast-gel-b5/for/sensitive-skin