La Roche-Posay Anthelios for acne-prone skin

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Questions and answers

What the research says

• A mixture of propanediol, xylitol, and caprylic acid demonstrated in vitro antimicrobial activity against C. acnes and S. aureus, reduced 5-alpha reductase expression, and decreased skin oiliness, porphyrin, and inflammatory lesions in participants over 28 days.

  Molecules, 2021

• Topical application of 1,3-propanediol at various concentrations, alone or combined with butylene glycol and/or glycerol, increased skin hydration and reduced trans epidermal water loss in 30 healthy female subjects over an 8-hour period, with the 15% concentration and the addition of glycerol providing greater benefits.

  International Journal of Cosmetic Science, 2024

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• Parsol 1789 and Eusolex 8020 provided slightly better photoprotection than oxybenzone in both normal and sensitized human skin when assessed using pigmentation end points, whereas all three sunscreens performed similarly against UVA-induced erythema.

  Journal of the American Academy of Dermatology, 1987

• Maximal topical applications of 6% bemotrizinol in a model sunscreen formulation did not result in meaningful systemic exposure in humans.

  Regulatory Toxicology and Pharmacology, 2023

• Microencapsulation of ethylhexyl triazone in lipid microparticles significantly reduced its in vivo human stratum corneum penetration by 45.7% compared to the nonencapsulated sunscreen.

  Skin Pharmacology and Physiology, 2019

• A topical sunscreen containing octyl triazone, phenylbenzimidazole sulfonic acid, and methylbenzylidene camphor prevented UVB-induced suppression of intercellular adhesion molecule-1 expression and mixed-lymphocyte reaction in epidermal cell cultures compared to control sunscreens with comparable SPF lacking octyl triazone.

  Toxicology in Vitro, 1994

• Encapsulation of ethylhexyl methoxycinnamate and butyl methoxydibenzoylmethane in lipid microparticles significantly reduced their in vivo human skin penetration compared to nonencapsulated filters.

  Skin Pharmacology and Physiology, 2011

• Microencapsulation of the BMDBM/HP-beta-CD complex in lipid microparticles significantly decreased the percutaneous penetration of the UV filter into the stratum corneum of human volunteers compared to the non-encapsulated sunscreen agent.

  Journal of Pharmaceutical and Biomedical Analysis, 2011

• Following human skin application of an O/W emulsion containing 2% BMDBM loaded in lipospheres, 15% of the sunscreen accumulated in the uppermost layers of the stratum corneum without remarkably modifying skin permeation compared to unencapsulated sunscreen.

  Skin Pharmacology and Physiology, 2008

• The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.

  Journal of Cosmetic Dermatology, 2020

• Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.

  International Journal of Cosmetic Science, 2001

• Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects.

  Journal of Drugs in Dermatology, 2012

Ingredients

Water, Alcohol Denat, Homosalate, Ethylhexyl Salicylate, Butyl Methoxydibenzoylmethane, Ethylhexyl Triazone, Octocrylene, Glycerin, Propanediol, Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine, C12-22 Alkyl Acrylate Hydroxyethylacrylate Copolymer, Diisopropyl Adipate, Diisopropyl Sebacate, Dicaprylyl Ether, Triethanolamine, Tocopherol, Phenylbenzimidazole Sulfonic Acid, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Caprylyl Glycol, Drometrizole Trisiloxane, Sodium Polyacrylate, Trisodium Ethylenediamine Disuccinate, Parfum

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.