# La Mer The Regenerating Serum for dry sensitive skin

**Lovi Fit: High fit for dry sensitive skin.**
Dry Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/ca/p/la-mer/the-regenerating-serum/for/dry-sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Brand: [La Mer](https://lovi.care/skincare/ca/brands/la-mer)
Category: [Serums and treatments](https://lovi.care/skincare/ca/best/serums)

This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best serums for dry sensitive skin.

## Why this fit

- Highly suitable for your dry skin, this serum leverages Algae Extract and Yeast Extract to significantly improve skin elasticity and texture, addressing your concerns of dryness and flakiness.
- Glycerin and Hydrogenated Lecithin further enhance hydration and support your skin's barrier function, while dipotassium glycyrrhizate offers soothing benefits for your sensitive skin.
- The formulation is safe for your dry and sensitive skin, containing no harsh or irritating ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ca/p/la-mer/the-regenerating-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/ca/p/la-mer/the-regenerating-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/ca/p/la-mer/the-regenerating-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/ca/p/la-mer/the-regenerating-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/ca/p/la-mer/the-regenerating-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/ca/p/la-mer/the-regenerating-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/ca/p/la-mer/the-regenerating-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/ca/p/la-mer/the-regenerating-serum/for/dry-sensitive-skin): High (this page)
- [Oily acne-prone skin](https://lovi.care/skincare/ca/p/la-mer/the-regenerating-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Miracle Broth, Acetyl Hexapeptide-8, Niacinamide, Algae Extract, Glycerin

## What the research says

- Topical application of 1% Fucus vesiculosus extract gel twice daily for five weeks significantly decreased skin thickness and improved elasticity in human cheek skin compared with controls. ([Journal of Cosmetic Science, 2002](https://pubmed.ncbi.nlm.nih.gov/11917251/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- A topical formulation containing panthenol, niacinamide, and dipotassium glycyrrhizate increased skin hydration by 74.1% and reduced transepidermal water loss by 13.5% at 28 days compared to baseline and untreated control in 35 individuals with xerosis. ([Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/42108609/))
- Lecithin-based nanoemulsions showed superior viability in human skin cells compared to SDS-based formulations, with components remaining in superficial stratum corneum layers indicating low skin irritation risk. ([International Journal of Pharmaceutics, 2020](https://pubmed.ncbi.nlm.nih.gov/32165223/))
- Treatment with cross-linked hyaluronic acid-based microneedle patches combined with acetyl hexapeptide-8 or epidermal growth factor significantly improved wrinkles and skin hydration compared to the patch alone in Korean females over 29 days. ([Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/))
- Argireline treatment twice daily for 4 weeks produced a significant anti-wrinkle effect with 48.9% total efficacy and decreased skin roughness in Chinese subjects compared with 0% efficacy and no decrease in roughness in the placebo group. ([American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/))
- Acetyl hexapeptide-3 and tripeptide-10 citrulline demonstrated antiwrinkle efficacy and decreased transepidermal water loss in twenty-four healthy volunteers compared to control groups, though synergistic effects between the two peptides remained unclear. ([Journal of Cosmetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28150423/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Treatment with lipid algae extract reduced the level of oxidized proteins in human keratinocytes and stratum corneum skin cells. ([Annals of the New York Academy of Sciences, 2004](https://pubmed.ncbi.nlm.nih.gov/15247018/))
- Topical astaxanthin-loaded algae extract hydrogel and lipogel formulations exhibited the highest antioxidant activity and successful in vitro release, suggesting their potential as anti-aging formulations. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29745467/))
- Antarctic marine algae extracts increased cell viability, protected against inflammation, and enhanced the barrier integrity of human intestinal and keratinocyte cell lines damaged by lipopolysaccharide or ultraviolet radiation. ([Marine Drugs, 2022](https://pubmed.ncbi.nlm.nih.gov/36135751/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))

## What reviewers say

Users with dry, mature, or sensitive skin frequently praise this serum for its immediate soothing and plumping effects, often noting a visible improvement in skin texture and radiance. Many experience hydration and a reduction in fine lines, though a significant portion of reviewers feel the anti-aging results do not justify the extremely high price point compared to other market alternatives.

- Liked: Deeply Hydrating (mostly mentioned)
- Disliked: Extremely High Price (mostly mentioned)
- Liked: Luxurious Feel (often mentioned)
- Liked: Smooths Skin Texture (often mentioned)
- Liked: Soothing & Calming (sometimes noted)
- Disliked: Poor Pump Design (sometimes noted)
- Disliked: Caused Breakouts/Irritation (rarely noted)
- Disliked: Strong Fragrance (rarely noted)

## How to apply

- Use this PM routine for your evening skincare. Start using the serum 3 times a week and increase to daily use if your skin feels comfortable.
- Apply the serum after cleansing and toner, but right before your moisturizer. This step locks in deep hydration for dry skin.
- Gently press 2-3 drops of the serum into your skin using your palms. Let it absorb completely for a minute ⏱ before applying your next product.
- Since your skin is sensitive, apply the serum on completely dry skin for better tolerance and less irritation.
- Avoid the sensitive eye area during application. Always do a patch test before your first use to ensure your skin reacts well.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes La Mer The Regenerating Serum a great fit for dry sensitive skin?

This serum is a great fit because it uses algae extract and yeast extract to improve texture and dryness, while glycerin and dipotassium glycyrrhizate boost hydration and calm sensitive skin.
Sources: [Journal of Cosmetic Science, 2002](https://pubmed.ncbi.nlm.nih.gov/11917251/)

### Which ingredients make this serum a good fit for dry sensitive skin?

This serum is a great fit because it contains glycerin and algae extract to deeply boost hydration and smooth out dryness, while dipotassium glycyrrhizate helps calm sensitive skin. These ingredients work safely together to restore moisture and improve skin texture without causing irritation.
Sources: [Journal of Cosmetic Science, 2002](https://pubmed.ncbi.nlm.nih.gov/11917251/)

### What does Miracle Broth do for dry sensitive skin?

Miracle Broth helps calm and soothe dry sensitive skin by reducing irritation and restoring a comfortable feel. This type of skin needs gentle, hydrating ingredients and barrier-repairing agents like niacinamide or soothing plant extracts to stay calm and moisturized.
Sources: [Marine Drugs, 2022](https://pubmed.ncbi.nlm.nih.gov/36005543/), [International Journal of Cosmetic Science, 2022](https://pubmed.ncbi.nlm.nih.gov/34813665/)

### What does Argireline do for dry sensitive skin?

Argireline helps smooth fine lines and keeps skin soft, but dry sensitive skin needs added moisture and soothing ingredients to feel fully comfortable. It is unlikely to cause irritation when used as directed, yet a product of this type for dry sensitive skin needs rich hydrators and calming agents to prevent dryness and protect the skin barrier.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/), [International Journal of Molecular Sciences, 2025](https://pubmed.ncbi.nlm.nih.gov/40565185/)

### Where does this serum go in a skincare routine for dry sensitive skin?

This serum goes in the evening routine after cleansing and toning, and before moisturizing. Putting treatments in the evening provides simplicity and extra safety around sun exposure for dry and sensitive skin.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first to deliver hydration and soothing ingredients, followed by your retinol once the serum absorbs. This layered approach helps calm potential irritation while keeping your skin soft and comfortable.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/)

### How often should I use this serum?

This serum is a great fit for your dry sensitive skin and works best when applied in the evening. Glycerin and hydrogenated lecithin help keep your skin hydrated and supported, while the formula is unlikely to cause irritation.

### Can this serum clog pores, cause breakouts or purging for dry sensitive skin?

This serum is unlikely to clog pores or cause breakouts for dry sensitive skin because its formulation avoids harsh or irritating ingredients and includes soothing components. Reviewers rarely report breakouts or irritation with use.

### Is this serum fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (parfum, linalool, limonene, citronellol, and geraniol).

## Alternatives for dry sensitive skin

- [KraveBeauty Great Barrier Relief](https://lovi.care/skincare/ca/p/kravebeauty/great-barrier-relief/for/dry-sensitive-skin) — High fit — CA$40.00 at Amazon
- [The Ordinary Matrixyl 10% + HA](https://lovi.care/skincare/ca/p/the-ordinary/matrixyl-10-ha/for/dry-sensitive-skin) — High fit — CA$14.40 at Amazon
- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/ca/p/skin1004/probio-cica-intensive-ampoule/for/dry-sensitive-skin) — High fit — CA$24.44 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/ca/p/cerave/hydrating-facial-cleanser/for/dry-sensitive-skin) — Superior fit — CA$20.19 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/ca/p/clarins/soothing-toning-lotion/for/dry-sensitive-skin) — Superior fit — CA$49.00 at Amazon
- Moisturizer with Sun Protection: [d'Alba UVessence Mild Waterfull Sun Cream SPF 50](https://lovi.care/skincare/ca/p/d-alba/uvessence-mild-waterfull-sun-cream-spf-50/for/dry-sensitive-skin) — Superior fit — CA$38.00 at Amazon

## Where to buy

- Sephora: CA$585.00 (https://www.sephora.com/ca/en/product/the-regenerating-serum-P450290?skuId=2284164)
Prices checked 10 Oct 2026.

## Ingredients

Water, Algae Extract, Dimethicone, Hdi Trimethylol Hexyllactone Crosspolymer, Hydrogenated Polyisobutene, Caprylic Capric Myristic Stearic Triglyceride, Polysilicone-11, Peg-8 Dimethicone, Peg-10 Dimethicone, Yeast Faex Extrait De Levure Extract, Citrus Aurantifolia Peel Extract, Sigesbeckia Orientalis Extract, Polygonum Cuspidatum Root Extract, Saccharomyces Lysate Extract, Sesamum Indicum Seed Oil, Eucalyptus Globulus Oil Leaf Eucalyptus Oil Leaf, Sesamum Indicum Seed Powder, Medicago Sativa Seed Powder, Helianthus Annuus Seedcake Sunflower Seedcake, Prunus Amygdalus Dulcis Seed Meal Seed, Sodium Gluconate, Copper Gluconate, Calcium Gluconate, Magnesium Gluconate, Zinc Gluconate, Tocopheryl Succinate, Niacin, Vitis Vinifera Seed Extract Grape Seed Extract, Rosmarinus Officinalis Leaf Extract Rosemary Leaf Extract, Punica Granatum Fruit Juice, Bupleurum Falcatum Root Extract, Citrus Reticulata Peel Extract Tangerine Peel Extract, Narcissus Tazetta Bulb Extract, Mimosa Tenuiflora Bark Extract, Betula Alba Bark Extract, Chlorella Vulgaris Extract, Humulus Lupulus Extract, Laureth-4, Corallina Officinalis Extract, Glycine Soja Seed Extract Soybean Seed Extract, Micrococcus Lysate, Whey Lactis Proteine Du Petit-Lait Protein, Tartaric Acid, Glycerin, Hydrolyzed Wheat Protein, Laureth-23, Butylene Glycol, Ammonium Acryloyldimethyltaurate Beheneth-25 Methacrylate Crosspolymer, Sucrose, Coenzyme A, Acetyl Glucosamine, Caffeine, Dipalmitoyl Hydroxyproline, Linoleic Acid, Tetraacetylphytosphingosine, Alcaligenes Polysaccharides, Bifida Lysate Ferment, Pentylene Glycol, Dipotassium Glycyrrhizate, Palmitoyl Oligopeptide, Peg-8, Sorbitol, Tocopheryl Acetate, Eryngium Maritimum Extract, Sodium Hydroxide, Hydrogenated Lecithin, Hydroxypropyl Cyclodextrin, Nordihydroguaiaretic Acid, Cyclodextrin, Maltodextrin, Acetyl Hexapeptide-8, Glyceryl Polymethacrylate, Glycosaminoglycans, Gold, Tourmaline, Linolenic Acid, Silica, Ethylbisiminomethylguaiacol Manganese Chloride, Disodium Edta, Potassium Sorbate, Phenoxyethanol, Parfum, Hydroxycitronellal, Linalool, Limonene, Citronellol, Geraniol, Green 5 Ci 61570
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/la-mer/the-regenerating-serum/for/dry-sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/la-mer/the-regenerating-serum/for/dry-sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/la-mer/the-regenerating-serum/for/dry-sensitive-skin
- Germany: https://lovi.care/skincare/de/p/la-mer/the-regenerating-serum/for/dry-sensitive-skin
- France: https://lovi.care/skincare/fr/p/la-mer/the-regenerating-serum/for/dry-sensitive-skin
- Italy: https://lovi.care/skincare/it/p/la-mer/the-regenerating-serum/for/dry-sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/la-mer/the-regenerating-serum/for/dry-sensitive-skin
- Spain: https://lovi.care/skincare/es/p/la-mer/the-regenerating-serum/for/dry-sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/la-mer/the-regenerating-serum/for/dry-sensitive-skin (this page)
- Australia: https://lovi.care/skincare/au/p/la-mer/the-regenerating-serum/for/dry-sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/la-mer/the-regenerating-serum/for/dry-sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/la-mer/the-regenerating-serum/for/dry-sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/la-mer/the-regenerating-serum/for/dry-sensitive-skin