# Kiehl's Ultra Pure High-Potency Serum for sensitive skin

**Lovi Fit: Average fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/ca/p/kiehl-s/ultra-pure-high-potency-serum/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Brand: [Kiehl's](https://lovi.care/skincare/ca/brands/kiehl-s)
Category: [Serums and treatments](https://lovi.care/skincare/ca/best/serums)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for sensitive skin; other serums fit it better.

## Why this fit

- Offers excellent hydration for your normal skin due to the presence of glycerin and hyaluronic acid, which support but do not directly target your redness and irritation.
- The humectant action of glycerin and hyaluronic acid is highly suitable for normal skin, providing general moisturizing benefits.
- The product is safe for your normal skin with sensitivity, as it lacks prohibited or harsh ingredients that could cause irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ca/p/kiehl-s/ultra-pure-high-potency-serum/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/ca/p/kiehl-s/ultra-pure-high-potency-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/ca/p/kiehl-s/ultra-pure-high-potency-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/ca/p/kiehl-s/ultra-pure-high-potency-serum/for/sensitive-skin): Average (this page)
- [Acne-prone skin](https://lovi.care/skincare/ca/p/kiehl-s/ultra-pure-high-potency-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/ca/p/kiehl-s/ultra-pure-high-potency-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/ca/p/kiehl-s/ultra-pure-high-potency-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/ca/p/kiehl-s/ultra-pure-high-potency-serum/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/ca/p/kiehl-s/ultra-pure-high-potency-serum/for/oily-acne-prone-skin): High

## Key ingredients

Niacinamide, Hyaluronic Acid, Glycerin

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))

## Why other serums fit sensitive skin better

- Topical application of TAT-SOD significantly suppresses UVB-induced erythema formation, blood flow rise, and apoptotic sunburn cell formation in human volunteers compared to a vehicle control. ([European Journal of Pharmaceutics and Biopharmaceutics, 2016](https://pubmed.ncbi.nlm.nih.gov/27460952/))

## What reviewers say

Based on a very large amount of data, this collection of minimalist serums is widely praised for its fast-absorbing, non-sticky textures and efficacy in targeting specific skin concerns like dryness, excess oil, and uneven texture. The Hyaluronic Acid version is lauded for immediate plumping, the Niacinamide serum is a favorite for controlling shine without irritation, and the Glycolic Acid variant is effective for smoothing skin, though it requires caution for sensitive types.

- Liked: Fast-absorbing texture (mostly mentioned)
- Liked: Effective oil control (often mentioned)
- Liked: Gentle minimalist formula (often mentioned)
- Liked: Immediate hydration (often mentioned)
- Disliked: High price point (often mentioned)
- Liked: Visible skin smoothing (sometimes noted)
- Disliked: Lack of dramatic results (sometimes noted)
- Disliked: Packaging concerns (rarely noted)
- Disliked: Potential irritation (rarely noted)
- Disliked: Texture preference (rarely noted)

## How to apply

- Use your serum in the PM routine, starting 3 times a week before building up to daily use if your skin is happy.
- Apply the serum after cleansing and toning, but before putting on your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏱ for it to soak in.
- Since your skin is sensitive and easily irritated, apply the serum on completely dry skin to help keep it calm.
- Always do a patch test before your first use and avoid getting the serum too close to your eyes .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Kiehl's Ultra Pure High-Potency Serum work for sensitive skin?

This serum works well for sensitive skin because it provides safe and steady moisture without any harsh ingredients, though it is not specifically designed to calm redness and irritation. A product of this type needs soothing ingredients like niacinamide and antioxidants to properly care for sensitive skin.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this serum a good fit for sensitive skin?

Glycerin and hyaluronic acid make this serum a good fit by providing general moisturizing benefits and keeping your skin soft and smooth. Because this product does not directly target redness and irritation, a treatment for sensitive skin needs soothing ingredients like niacinamide and antioxidants to properly calm the skin.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Niacinamide do for sensitive skin?

Niacinamide helps calm sensitive skin by strengthening the skin barrier and reducing redness and irritation. It is very well tolerated and may improve overall comfort and resilience with regular use.
Sources: [Cutis, 2005](https://pubmed.ncbi.nlm.nih.gov/16209160/), [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/)

### What does Hyaluronic Acid do for sensitive skin?

Hyaluronic acid helps calm and hydrate sensitive skin while supporting the skin barrier to keep it soft and comfortable. Clinical studies show it improves surface moisture and reduces dryness, roughness, and redness without irritation.
Sources: [Journal of Drugs in Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/41037531/), [Journal of Cosmetic Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29356277/)

### Where does it go in a skincare routine for sensitive skin?

This treatment goes in the evening routine after your soothing toner and before your moisturizer. It is safe for your sensitive skin because it lacks harsh ingredients, but a product for this skin needs ingredients that directly target redness and irritation.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first to keep your skin hydrated and comfortable. To better calm redness and irritation on sensitive skin, a product of this type needs added soothing ingredients.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### How often should I use it?

You can use this treatment in your evening routine, applying it after cleansing and toning and before your moisturizer. Sensitive skin works best with products that calm redness and irritation, so a product of this type needs soothing ingredients like Centella asiatica alongside hydration.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can this serum clog pores, cause breakouts or purging for sensitive skin?

This serum is unlikely to cause breakouts or clog pores on sensitive skin because it lacks heavy, pore-clogging ingredients. A product for this skin needs gentle, calming ingredients like centella asiatica or soothing botanical extracts to actively target redness and irritation.

## Alternatives for sensitive skin

- [COSRX The Vitamin C 23 Serum](https://lovi.care/skincare/ca/p/cosrx/the-vitamin-c-23-serum/for/sensitive-skin) — High fit — CA$33.98 at Amazon
- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/ca/p/skin1004/probio-cica-intensive-ampoule/for/sensitive-skin) — High fit — CA$24.44 at Amazon
- [The Ordinary Matrixyl 10% + HA](https://lovi.care/skincare/ca/p/the-ordinary/matrixyl-10-ha/for/sensitive-skin) — High fit — CA$14.40 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/ca/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — CA$44.95 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/ca/p/clarins/soothing-toning-lotion/for/sensitive-skin) — Superior fit — CA$49.00 at Amazon
- Moisturizer with Sun Protection: [Torriden DIVE-IN Mild Sunscreen](https://lovi.care/skincare/ca/p/torriden/dive-in-mild-sunscreen/for/sensitive-skin) — Superior fit — CA$27.34 at Amazon

## Where to buy

No store in Canada has a checked price for this product, so the page shows none.

## Ingredients

Water, Glycerin, Hyaluronic Acid, Phenoxyethanol, Chlorphenesin, Tetrasodium Glutamate Diacetate, Citric Acid
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/kiehl-s/ultra-pure-high-potency-serum/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/kiehl-s/ultra-pure-high-potency-serum/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/kiehl-s/ultra-pure-high-potency-serum/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/kiehl-s/ultra-pure-high-potency-serum/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/kiehl-s/ultra-pure-high-potency-serum/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/kiehl-s/ultra-pure-high-potency-serum/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/kiehl-s/ultra-pure-high-potency-serum/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/kiehl-s/ultra-pure-high-potency-serum/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/kiehl-s/ultra-pure-high-potency-serum/for/sensitive-skin (this page)
- Australia: https://lovi.care/skincare/au/p/kiehl-s/ultra-pure-high-potency-serum/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/kiehl-s/ultra-pure-high-potency-serum/for/sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/kiehl-s/ultra-pure-high-potency-serum/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/kiehl-s/ultra-pure-high-potency-serum/for/sensitive-skin