# Kate Somerville Kx Active Concentrates Bio-Mimicking Peptides Serum for mature skin

**Lovi Fit: Superior fit for mature skin.**
Normal Skin Fit: High · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/ca/p/kate-somerville/kx-active-concentrates-bio-mimicking-peptides-serum/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Brand: [Kate Somerville](https://lovi.care/skincare/ca/brands/kate-somerville)
Category: [Serums and treatments](https://lovi.care/skincare/ca/best/serums)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best serums for mature skin.

## Why this fit

- Excellent compatibility with your normal skin, as the bio-mimicking peptides like sh-oligopeptide-2 and sh-oligopeptide-1 effectively target wrinkles and fine lines by promoting collagen synthesis and skin elasticity.
- Sodium hyaluronate and glycerin provide superior hydration, ensuring your skin remains plump and supple.
- The formulation is safe for your skin, containing soothing ingredients like sodium hyaluronate and panthenol with no harsh or irritating components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ca/p/kate-somerville/kx-active-concentrates-bio-mimicking-peptides-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/ca/p/kate-somerville/kx-active-concentrates-bio-mimicking-peptides-serum/for/dry-skin): Superior
- [Combination skin](https://lovi.care/skincare/ca/p/kate-somerville/kx-active-concentrates-bio-mimicking-peptides-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/ca/p/kate-somerville/kx-active-concentrates-bio-mimicking-peptides-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/ca/p/kate-somerville/kx-active-concentrates-bio-mimicking-peptides-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/ca/p/kate-somerville/kx-active-concentrates-bio-mimicking-peptides-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/ca/p/kate-somerville/kx-active-concentrates-bio-mimicking-peptides-serum/for/mature-skin): Superior (this page)
- [Dry sensitive skin](https://lovi.care/skincare/ca/p/kate-somerville/kx-active-concentrates-bio-mimicking-peptides-serum/for/dry-sensitive-skin): Superior
- [Oily acne-prone skin](https://lovi.care/skincare/ca/p/kate-somerville/kx-active-concentrates-bio-mimicking-peptides-serum/for/oily-acne-prone-skin): High

## Key ingredients

Bio-Mimicking Peptides, Sodium Hyaluronate, Acetyl Glutamine, Spondias Mombin Extract Pulp, Mangifera Indica Extract Pulp

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Mangifera indica extract-loaded green nanolipid carriers in topical emulsion amplified overall antioxidant effectiveness and antiaging activity compared to vehicle in human volunteers over three months. ([Biomedicines, 2022](https://pubmed.ncbi.nlm.nih.gov/36140367/))
- Mangifera indica extract reduced lipid production by 40% in sebocytes, improved sebum quality and quantity in Caucasian volunteers, reduced porphyrins expression, and decreased C. acnes lipase activity by 29% compared to placebo while protecting microbiota equilibrium. ([Molecules, 2022](https://pubmed.ncbi.nlm.nih.gov/35897945/))
- Mango butter-based foot care cream repaired worn and cracked skin in all human volunteers and exhibited a significant healing response in rat excision and incision wound models compared to untreated conditions. ([Indian Journal of Pharmaceutical Sciences, 2008](https://pubmed.ncbi.nlm.nih.gov/20046792/))

## What reviewers say

Users with mature, dry, or dull skin frequently praise this serum for its ability to visibly smooth fine lines and improve skin elasticity, often describing a "tightening" effect. While many appreciate its lightweight, hydrating texture and lack of irritation, a significant number of reviewers feel the high price tag is not justified by the results, and recent feedback suggests the product may be difficult to find or discontinued.

- Liked: Improves skin texture (often mentioned)
- Liked: Lightweight hydration (often mentioned)
- Disliked: High price (often mentioned)
- Liked: Firming effect (sometimes noted)
- Liked: Gentle formula (sometimes noted)
- Disliked: Availability issues (sometimes noted)
- Disliked: Lack of results (sometimes noted)
- Disliked: Unpleasant scent (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week, and work up to daily use if your skin likes it.
- Apply this serum after your toner and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- You can apply the serum on dry skin for the best results against fine lines.
- Always do a patch test before your first use and avoid the sensitive eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Kate Somerville Bio-Mimicking Peptides Serum one of the best fits for mature skin?

This serum is one of the best fits for mature skin because its bio-mimicking peptides target wrinkles by boosting collagen and elasticity, while sodium hyaluronate and glycerin keep skin plump and hydrated. It also features soothing ingredients like panthenol with no harsh components, making it a safe choice for daily use.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Which ingredients make this serum a good fit for mature skin?

Bio-mimicking peptides like sh-oligopeptide-2 and sh-oligopeptide-1 make this serum a great fit because they target wrinkles by boosting collagen and firmness. Sodium hyaluronate and glycerin also help keep skin plump and smooth, while panthenol soothes and keeps the skin calm.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### What do Bio-Mimicking Peptides do for mature skin?

Bio-Mimicking Peptides help improve skin firmness and smooth out the look of fine lines on mature skin. They support the skin's natural support network to keep it feeling plump and elastic. This type of product works best when it also includes rich moisturizers and firming ingredients to help dry or aging skin stay soft and smooth.
Sources: [Journal of Cosmetic Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25817264/)

### What does Hyaluronic Acid do for mature skin?

Hyaluronic acid helps mature skin by deeply boosting moisture, improving elasticity, and smoothing the appearance of fine lines and wrinkles. Regular use keeps the skin looking plump and soft while supporting overall firmness and hydration.
Sources: [Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/), [Skin Research and Technology, 2024](https://pubmed.ncbi.nlm.nih.gov/38591218/)

### Where does this serum go in a skincare routine for mature skin?

This serum goes in your evening routine as a treatment step, applied after cleansing and before your moisturizer. Putting it on at night helps keep your skin safe around sun exposure while working on fine lines.

### Can I use this serum with retinol, and in what order?

Yes, you can use this serum with retinol by applying your retinol first and following with this treatment to keep your mature skin calm and hydrated. Because this formula contains soothing ingredients like sodium hyaluronate and panthenol, it is unlikely to irritate your skin when paired with strong actives.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### How often should I use this serum?

Use this serum in the evening as part of your routine. This timing keeps your routine simple and provides extra safety around sun exposure.

### Can this serum clog pores, cause breakouts or purging for mature skin?

This serum is unlikely to clog pores or cause breakouts for mature skin, as it contains soothing and hydrating ingredients with no harsh components. It helps keep your skin calm and smooth while providing deep moisture.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Is this serum fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (benzyl alcohol).

## Alternatives for mature skin

- [Dr.Althea Vitamin C Boosting Serum](https://lovi.care/skincare/ca/p/dr-althea/vitamin-c-boosting-serum/for/mature-skin) — High fit — CA$27.99 at Amazon
- [The Ordinary Matrixyl 10% + HA](https://lovi.care/skincare/ca/p/the-ordinary/matrixyl-10-ha/for/mature-skin) — High fit — CA$14.40 at Amazon
- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/ca/p/skin1004/probio-cica-intensive-ampoule/for/mature-skin) — High fit — CA$24.44 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/ca/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — CA$44.95 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/ca/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — CA$31.98 at Amazon
- Moisturizer: [Obagi Hydrate Luxe Moisture-Rich Cream](https://lovi.care/skincare/ca/p/obagi/hydrate-luxe/for/mature-skin) — Superior fit — CA$103.73 at Amazon

## Where to buy

No store in Canada has a checked price for this product, so the page shows none.

## Ingredients

Water, Ppg-24-Glycereth-24, Glycerin, Propanediol, Spondias Mombin Extract Pulp, Mangifera Indica Extract Pulp, Musa Sapientum Extract Pulp, Acetyl Glutamine, Sodium Hyaluronate, Acer Rubrum Extract, Sh-Polypeptide-1, Sh-Oligopeptide-2, Sh-Oligopeptide-1, Sh-Polypeptide-9, Sh-Polypeptide-11, Panthenol, Cichorium Intybus Leaf Extract, Zinc Pca, Caprylyl Glycol, Glycine Soja Seed Extract Soybean Seed Extract, Lecithin, Sclerotium Gum, Pullulan, 1,2-Hexanediol, Bacillus Folic Acid Extract Ferment, Caprylhydroxamic Acid, Silica, Adenosine, Benzyl Alcohol, Potassium Sorbate, Capryl Glycol, Butylene Glycol, Hexylene Glycol, Disodium Edta, Citric Acid, Sodium Benzoate, Xanthan Gum
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/kate-somerville/kx-active-concentrates-bio-mimicking-peptides-serum/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/kate-somerville/kx-active-concentrates-bio-mimicking-peptides-serum/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/kate-somerville/kx-active-concentrates-bio-mimicking-peptides-serum/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/kate-somerville/kx-active-concentrates-bio-mimicking-peptides-serum/for/mature-skin
- France: https://lovi.care/skincare/fr/p/kate-somerville/kx-active-concentrates-bio-mimicking-peptides-serum/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/kate-somerville/kx-active-concentrates-bio-mimicking-peptides-serum/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/kate-somerville/kx-active-concentrates-bio-mimicking-peptides-serum/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/kate-somerville/kx-active-concentrates-bio-mimicking-peptides-serum/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/kate-somerville/kx-active-concentrates-bio-mimicking-peptides-serum/for/mature-skin (this page)
- Australia: https://lovi.care/skincare/au/p/kate-somerville/kx-active-concentrates-bio-mimicking-peptides-serum/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/kate-somerville/kx-active-concentrates-bio-mimicking-peptides-serum/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/kate-somerville/kx-active-concentrates-bio-mimicking-peptides-serum/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/kate-somerville/kx-active-concentrates-bio-mimicking-peptides-serum/for/mature-skin