# Jole Azelaic Acid 10% Serum for dry skin

**Lovi Fit: Average fit for dry skin.**
Dry Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/ca/p/jole/azelaic-acid-10-serum/for/dry-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Brand: [Jole](https://lovi.care/skincare/ca/brands/jole)
Category: [Serums and treatments](https://lovi.care/skincare/ca/best/serums)

This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for dry skin; other serums fit it better.

## Why this fit

- Offers moderate treatment for acne lesions and evening skin tone due to the presence of azelaic acid and niacinamide, which reduce blemishes and improve skin clarity for your dry or flaky skin.
- Glyceryl Glucoside and Squalane provide hydration, offering general skincare benefits that support your dry skin.
- The product is safe for your dry skin, with no risks of irritation due to the absence of harsh ingredients and the inclusion of soothing agents like Squalane and Bisabolol.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ca/p/jole/azelaic-acid-10-serum/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/ca/p/jole/azelaic-acid-10-serum/for/dry-skin): Average (this page)
- [Combination skin](https://lovi.care/skincare/ca/p/jole/azelaic-acid-10-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/ca/p/jole/azelaic-acid-10-serum/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/ca/p/jole/azelaic-acid-10-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/ca/p/jole/azelaic-acid-10-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/ca/p/jole/azelaic-acid-10-serum/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/ca/p/jole/azelaic-acid-10-serum/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/ca/p/jole/azelaic-acid-10-serum/for/oily-acne-prone-skin): High

## Key ingredients

Azelaic Acid, Niacinamide, Squalane, Bisabolol, Allantoin

## What the research says

- Azelaic acid nanocrystal hydrogel 10% achieved a higher success rate and greater lesion reduction than azelaic acid cream 20% in patients with mild to moderate facial acne. ([Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/))
- Application of 15% azelaic acid gel significantly reduced post-inflammatory erythema and hyperpigmentation, decreased hemoglobin and melanin content, improved quality of life, and contributed to acne improvement in patients with mild to moderate acne compared to placebo. ([Dermatology and Therapy, 2024](https://pubmed.ncbi.nlm.nih.gov/38734843/))
- Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer. ([The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/))
- Topical application of glyceryl glucoside significantly increased AQP3 mRNA levels and reduced transepidermal water loss compared with vehicle-controlled areas in volunteer subjects. ([Skin Pharmacology and Physiology, 2012](https://pubmed.ncbi.nlm.nih.gov/22584263/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Topical application of a dermocosmetic containing Myrtus communis extract and azelaic acid reduced acne relapses and helped maintain remission compared to a light moisturizing cream in adult females in the acne maintenance phase over 16 weeks. ([Journal of the European Academy of Dermatology and Venereology, 2023](https://pubmed.ncbi.nlm.nih.gov/36729399/))
- Topical administration of 20% azelaic acid cream and 5% tranexamic acid solution comparably improved acne-related postinflammatory hyperpigmentation in patients with acne vulgaris, while tranexamic acid demonstrated a significantly better safety profile at week 4. ([Journal of Research in Medical Sciences, 2023](https://pubmed.ncbi.nlm.nih.gov/37213446/))
- Azelaic acid 15% gel showed comparable efficacy to adapalene 0.1% gel in reducing lesions, severity, and Dermatology Life Quality Index in women with adult acne, with significantly lower dryness and scaling, and demonstrated superiority during maintenance compared to no further treatment. ([Journal of the European Academy of Dermatology and Venereology, 2015](https://pubmed.ncbi.nlm.nih.gov/25399481/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))
- Application of an alpha-bisabolol-containing cream produced a significant skin-lightening effect in pigmented skin compared to a vehicle control in the majority of female subjects after 8 weeks. ([International Journal of Cosmetic Science, 2010](https://pubmed.ncbi.nlm.nih.gov/20642768/))
- The combination of allantoin, bisabolol, D-panthenol and dipotassium glycyrrhizinate reduces UVB-induced PGE2, inflammatory cytokines, and mitochondrial superoxide in human epidermal keratinocytes. ([International Journal of Cosmetic Science, 2024](https://pubmed.ncbi.nlm.nih.gov/38433250/))
- Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016](https://pubmed.ncbi.nlm.nih.gov/27475700/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment. ([Aesthetic Plastic Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29948103/))

## What reviewers say

Users highly recommend this serum for acne-prone and sensitive skin, noting its strong effectiveness in clearing active breakouts, reducing inflammation, and fading post-acne hyperpigmentation. The lightweight formula absorbs quickly and improves overall skin texture, though a small number of users experienced temporary dryness or a brief purging phase.

- Liked: Reduces acne breakouts (mostly mentioned)
- Liked: Fades post-acne marks (often mentioned)
- Liked: Absorbs very quickly (sometimes noted)
- Liked: Calms skin redness (sometimes noted)
- Disliked: Causes mild dryness (rarely noted)
- Disliked: Faulty pump dispenser (rarely noted)
- Disliked: Initial skin purging (rarely noted)

## How to apply

- Apply this serum PM, starting 3×/week and working up to daily use as your skin adjusts.
- Place the serum after cleansing and toner, but right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on slightly damp skin to help lock in extra moisture.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Jole Jole Azelaic Acid work for dry skin?

Jole Jole Azelaic Acid 10% Serum works decently for dry skin by helping clear blemishes and even out skin tone while providing moderate hydration. A product of this type needs richer hydrating and skin-repairing ingredients like ceramides, peptides, and deep moisturizers to truly give dry skin the exceptional nourishment and moisture it requires.
Sources: [Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/), [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/)

### Which ingredients make this serum a good fit for dry skin?

Squalane, glyceryl glucoside, and bisabolol make this serum a good fit for dry skin by providing essential hydration and keeping the skin calm without irritation. To fit dry skin even better, a treatment of this type needs deeply nourishing ingredients, ceramides, and peptides for strong skin barrier support.
Sources: [Skin Pharmacology and Physiology, 2012](https://pubmed.ncbi.nlm.nih.gov/22584263/)

### What does Niacinamide do for dry skin?

Niacinamide helps dry skin by strengthening the skin barrier, increasing hydration, and reducing water loss. It supports ceramide production and helps keep the surface smooth and calm. This ingredient tends to be very well tolerated and is unlikely to irritate dry skin.
Sources: [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/), [Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/42108609/)

### Where does this serum go in a skincare routine for dry skin?

This serum goes in your evening routine after cleansing and before moisturizing. Putting treatments in the evening provides simplicity and extra safety around sun exposure for your dry skin.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the retinol first and following with this treatment, or by using them on alternate nights to keep your dry skin calm. This product helps clear blemishes and even out skin tone while soothing dryness, but dry skin ultimately needs richer hydrating ingredients and barrier-supporting emollients to stay truly soft and comfortable.

### How often should I use this serum?

Apply this serum in your evening routine, starting once a week to see how your dry skin handles it before considering more frequent use. This product of this type needs rich moisturizers and soothing hydrators like squalane and bisabolol to keep dry skin comfortable.
Sources: [Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/), [Dermatology and Therapy, 2024](https://pubmed.ncbi.nlm.nih.gov/38734843/)

### Can this serum clog pores, cause breakouts or purging for dry skin?

This serum is unlikely to clog pores, but initial skin purging is a low possibility for your dry skin. A product of this type needs soothing and hydrating ingredients like squalane and bisabolol to keep dry skin calm and comfortable.
Sources: [Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for dry skin

- [KraveBeauty Great Barrier Relief](https://lovi.care/skincare/ca/p/kravebeauty/great-barrier-relief/for/dry-skin) — Superior fit — CA$40.00 at Amazon
- [SKIN1004 Madagascar Centella Tone Brightening Capsule Ampoule](https://lovi.care/skincare/ca/p/skin1004/madagascar-centella-tone-brightening-capsule-ampoule/for/dry-skin) — Superior fit — CA$22.49 at Amazon
- [The Ordinary Matrixyl 10% + HA](https://lovi.care/skincare/ca/p/the-ordinary/matrixyl-10-ha/for/dry-skin) — Superior fit — CA$14.40 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/ca/p/cerave/hydrating-facial-cleanser/for/dry-skin) — Superior fit — CA$20.19 at Amazon
- Hydrating Toner: [Dear, Klairs Supple Preparation Unscented Toner](https://lovi.care/skincare/ca/p/dear-klairs/supple-preparation-unscented-toner/for/dry-skin) — Superior fit — CA$27.99 at Amazon
- Moisturizer: [Tata Harper Repairative Moisturizer](https://lovi.care/skincare/ca/p/tata-harper/repairative-moisturizer/for/dry-skin) — Superior fit — CA$162.00 at Amazon

## Where to buy

No store in Canada has a checked price for this product, so the page shows none.

## Ingredients

Water, Ethoxydiglycol, Azelaic Acid, Niacinamide, Glyceryl Glucoside, Squalane, Bisabolol, Allantoin, Ammonium Acryloyldimethyltaurate Vp Copolymer, Valine, Proline, Lysine, Serine, Sorbitan Caprylate, 1,2 Propanediol, Benzoic Acid
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/jole/azelaic-acid-10-serum/for/dry-skin
- United Kingdom: https://lovi.care/skincare/uk/p/jole/azelaic-acid-10-serum/for/dry-skin
- Ireland: https://lovi.care/skincare/ie/p/jole/azelaic-acid-10-serum/for/dry-skin
- Germany: https://lovi.care/skincare/de/p/jole/azelaic-acid-10-serum/for/dry-skin
- France: https://lovi.care/skincare/fr/p/jole/azelaic-acid-10-serum/for/dry-skin
- Italy: https://lovi.care/skincare/it/p/jole/azelaic-acid-10-serum/for/dry-skin
- Netherlands: https://lovi.care/skincare/nl/p/jole/azelaic-acid-10-serum/for/dry-skin
- Spain: https://lovi.care/skincare/es/p/jole/azelaic-acid-10-serum/for/dry-skin
- Canada: https://lovi.care/skincare/ca/p/jole/azelaic-acid-10-serum/for/dry-skin (this page)
- Australia: https://lovi.care/skincare/au/p/jole/azelaic-acid-10-serum/for/dry-skin
- Singapore: https://lovi.care/skincare/sg/p/jole/azelaic-acid-10-serum/for/dry-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/jole/azelaic-acid-10-serum/for/dry-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/jole/azelaic-acid-10-serum/for/dry-skin