# HydroPeptide Power Serum for sensitive skin

**Lovi Fit: High fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: Excellent.

Page: https://lovi.care/skincare/ca/p/hydropeptide/power-serum/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Brand: [HydroPeptide](https://lovi.care/skincare/ca/brands/hydropeptide)
Category: [Serums and treatments](https://lovi.care/skincare/ca/best/serums)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for sensitive skin; a few serums fit it even better.

## Why this fit

- This serum is highly suitable for your normal skin, as Glycerin and Sodium Hyaluronate provide essential hydration without overwhelming it, while Hexapeptide-11 and Tetrahexyldecyl Ascorbate work to smooth texture and brighten your skin tone.
- The formula also offers supportive benefits for your redness and irritation by providing general hydration and soothing effects.
- It is safe for your sensitive skin due to the absence of harsh ingredients and the inclusion of soothing components like Oat Protein and Tocopherol.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ca/p/hydropeptide/power-serum/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/ca/p/hydropeptide/power-serum/for/dry-skin): Superior
- [Combination skin](https://lovi.care/skincare/ca/p/hydropeptide/power-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/ca/p/hydropeptide/power-serum/for/sensitive-skin): High (this page)
- [Acne-prone skin](https://lovi.care/skincare/ca/p/hydropeptide/power-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/ca/p/hydropeptide/power-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/ca/p/hydropeptide/power-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/ca/p/hydropeptide/power-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/ca/p/hydropeptide/power-serum/for/oily-acne-prone-skin): High

## Key ingredients

Palmitoyl Tripeptide-5, Hexapeptide-11, Acetyl Hexapeptide-30, Sodium Hyaluronate, Lemon Peel Extract

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- A 3-in-1 anti-aging topical night serum-in-oil applied once daily decreased wrinkles by 11%, increased skin firmness by 8%, reduced redness by 70%, and improved overall skin quality and complexion in 103 female subjects over 28 to 84 days compared to baseline. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30924254/))
- Supramolecular collagen nanoparticles composed of lactoferrin, recombinant human collagen, and palmitoyl tripeptide-5 improved transdermal efficiency by 69.90% and demonstrated moisturizing, whitening, wrinkle reduction, and firming effects. ([Colloids and Surfaces. B, Biointerfaces, 2025](https://pubmed.ncbi.nlm.nih.gov/39383579/))
- Hexapeptide-11 activated proteasome, autophagy, chaperones, and antioxidant response genes, protected fibroblasts against oxidative-stress-mediated premature cellular senescence, and improved skin elasticity in human subjects. ([Redox Biology, 2015](https://pubmed.ncbi.nlm.nih.gov/25974626/))
- Hexapeptide-11 reversibly downregulated ATM and p53 protein expression in intrinsically aged fibroblasts, extrinsically aged fibroblasts, and extrinsically aged dermal papillae cells at concentrations between 0.1% and 1.0% in vitro, thereby influencing the onset of cellular senescence. ([Journal of Cosmetic Science, 2013](https://pubmed.ncbi.nlm.nih.gov/23578831/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))

## What reviewers say

Users consistently praise this serum as a lightweight, non-greasy anti-aging powerhouse that visibly plumps and smooths the skin. While it is highly effective for hydrating dry skin and softening fine lines without irritating sensitive complexions, the high price point and distinct scent are occasional points of contention.

- Liked: Lightweight texture (mostly mentioned)
- Liked: Deep hydration (often mentioned)
- Liked: Visible anti-aging (often mentioned)
- Disliked: High price point (often mentioned)
- Liked: Gentle on skin (sometimes noted)
- Liked: Pleasant scent (sometimes noted)
- Disliked: Packaging size (rarely noted)
- Disliked: Scent dislike (rarely noted)
- Disliked: Slow results (rarely noted)

## How to apply

- Use your serum in the PM routine, starting 3 times a week before building up to daily use if your skin is happy.
- Apply the serum after cleansing and toning, but before putting on your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏱ for it to soak in.
- Since your skin is sensitive and easily irritated, apply the serum on completely dry skin to help keep it calm.
- Always do a patch test before your first use and avoid getting the serum too close to your eyes .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes HydroPeptide Power Serum a great fit for sensitive skin?

HydroPeptide Power Serum is a great fit for sensitive skin because it is free of harsh ingredients and includes calming components like oat protein and vitamin E. Glycerin and sodium hyaluronate help provide essential hydration, while peptides and vitamin C work to smooth texture and brighten your skin tone.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this serum a good fit for sensitive skin?

This serum is a great fit for sensitive skin because it avoids harsh ingredients and includes soothing components like Oat Protein and Tocopherol. These ingredients help keep skin calm while reducing redness and irritation.

### What does Palmitoyl Tripeptide-5 do for sensitive skin?

Palmitoyl Tripeptide-5 helps smooth fine lines and keeps skin looking firm and youthful. It is unlikely to irritate sensitive skin, but a product for this skin type also needs soothing ingredients to keep it calm and comfortable.
Sources: [Colloids and Surfaces. B, Biointerfaces, 2025](https://pubmed.ncbi.nlm.nih.gov/39383579/)

### What does Hexapeptide-11 do for sensitive skin?

Hexapeptide-11 helps protect sensitive skin against everyday stress and may improve firmness. Sensitive skin needs gentle ingredients that calm irritation and strengthen its natural barrier, such as soothing plant extracts and barrier-repairing lipids.
Sources: [Redox Biology, 2015](https://pubmed.ncbi.nlm.nih.gov/25974626/)

### Where does this serum go in a skincare routine for sensitive skin?

This serum goes in your evening routine, applied after your soothing toner and before your moisturizer. Putting treatments in the evening provides extra safety around sun exposure, and this formula is gentle enough for your skin because it lacks harsh ingredients and includes soothing components.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying your retinol product first and following with this serum to keep your skin calm and hydrated. This formula is safe for sensitive skin due to the lack of harsh ingredients and the presence of soothing components like oat protein and tocopherol.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/)

### How often should I use this serum?

You can use this treatment in the evening as part of your routine, or sometimes in the morning or twice a day if your skin likes it. It is safe for sensitive skin due to the absence of harsh ingredients and the inclusion of soothing components like oat protein and tocopherol.

### Can this serum clog pores, cause breakouts or purging for sensitive skin?

This serum is unlikely to clog pores or cause breakouts for sensitive skin because it is free of harsh, heavy ingredients and relies on lightweight hydration. It helps keep your skin calm and balanced without triggering irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetearyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for sensitive skin

- [COSRX The Vitamin C 23 Serum](https://lovi.care/skincare/ca/p/cosrx/the-vitamin-c-23-serum/for/sensitive-skin) — High fit — CA$33.98 at Amazon
- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/ca/p/skin1004/probio-cica-intensive-ampoule/for/sensitive-skin) — High fit — CA$24.44 at Amazon
- [The Ordinary Matrixyl 10% + HA](https://lovi.care/skincare/ca/p/the-ordinary/matrixyl-10-ha/for/sensitive-skin) — High fit — CA$14.40 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/ca/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — CA$44.95 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/ca/p/clarins/soothing-toning-lotion/for/sensitive-skin) — Superior fit — CA$49.00 at Amazon
- Moisturizer with Sun Protection: [Torriden DIVE-IN Mild Sunscreen](https://lovi.care/skincare/ca/p/torriden/dive-in-mild-sunscreen/for/sensitive-skin) — Superior fit — CA$27.34 at Amazon

## Where to buy

No store in Canada has a checked price for this product, so the page shows none.

## Ingredients

Water, Glycerin, Lactococcus Lysate Ferment, Butylene Glycol, Propanediol, Diethylhexyl Carbonate, Isopentyldiol, Pentylene Glycol, Diheptyl Succinate, Caprylyl Glycol, Hydroxyacetophenone, Olea Europaea Fruit Olive Fruit, Sodium Stearoyl Glutamate, Cetearyl Alcohol, Glyceryl Stearate, Potassium Olivoyl Hydrolyzed Oat Protein, Lysolecithin, Sclerotium Gum, Hexapeptide-11, Tetrahexyldecyl Ascorbate, 1,2-Hexanediol, Capryloyl Glycerin Sebacic Acid Copolymer, Phenylpropanol, Sorbitan Laurate, Pullulan, Xanthan Gum, Caprylic Capric Triglyceride, Glyceryl Oleate, Glycine Soja Seed Extract Soybean Seed Extract, Anogeissus Leiocarpus Bark Extract, Lemon Peel Extract, Palmitoyl Hexapeptide-19, Sodium Phytate, Hydroxyethylcellulose, Sodium Hyaluronate, Acetyl Dipeptide-1 Cetyl Ester, Citrus Aurantium Dulcis Peel Extract, Grapefruit Fruit Extract, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Bergamot Fruit Extract, Citrus Aurantifolia Peel Extract, Citrus Nobilis Fruit Extract Mandarin Orange Fruit Extract, Tangerine Peel Extract, Acetyl Hexapeptide-30, Barosma Betulina Leaf Extract, Vanilla Planifolia Fruit Extract, Vitis Vinifera Fruit Extract Grape Fruit Extract, Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine, Palmitoyl Tripeptide-5, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Tocopherol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/hydropeptide/power-serum/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/hydropeptide/power-serum/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/hydropeptide/power-serum/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/hydropeptide/power-serum/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/hydropeptide/power-serum/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/hydropeptide/power-serum/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/hydropeptide/power-serum/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/hydropeptide/power-serum/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/hydropeptide/power-serum/for/sensitive-skin (this page)
- Australia: https://lovi.care/skincare/au/p/hydropeptide/power-serum/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/hydropeptide/power-serum/for/sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/hydropeptide/power-serum/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/hydropeptide/power-serum/for/sensitive-skin