# Estée Lauder Futurist Peptide-Power Serum Primer for sensitive skin

**Lovi Fit: Average fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/ca/p/estee-lauder/futurist-peptide-power-serum-primer/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Brand: [Estée Lauder](https://lovi.care/skincare/ca/brands/estee-lauder)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/ca/best/moisturizers)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for sensitive skin; other moisturizers fit it better.

## Why this fit

- Offers moderate hydration and plumping benefits for normal skin due to glycerin and sodium hyaluronate, which support overall skin health and collagen stimulation with peptides like Acetyl Hexapeptide-8.
- While beneficial for general skin health, the formula does not specifically target your concerns of redness and irritation.
- The product is safe for your sensitive skin, as it lacks harsh ingredients and includes soothing components like whey protein.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ca/p/estee-lauder/futurist-peptide-power-serum-primer/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/ca/p/estee-lauder/futurist-peptide-power-serum-primer/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/ca/p/estee-lauder/futurist-peptide-power-serum-primer/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/ca/p/estee-lauder/futurist-peptide-power-serum-primer/for/sensitive-skin): Average (this page)
- [Acne-prone skin](https://lovi.care/skincare/ca/p/estee-lauder/futurist-peptide-power-serum-primer/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/ca/p/estee-lauder/futurist-peptide-power-serum-primer/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/ca/p/estee-lauder/futurist-peptide-power-serum-primer/for/mature-skin): Superior
- [Dry sensitive skin](https://lovi.care/skincare/ca/p/estee-lauder/futurist-peptide-power-serum-primer/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/ca/p/estee-lauder/futurist-peptide-power-serum-primer/for/oily-acne-prone-skin): Average

## Key ingredients

Acetyl Hexapeptide-8, Palmitoyl Hexapeptide-12, Sodium Hyaluronate, Glycerin, Tetrahexyldecyl Ascorbate

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Argireline treatment twice daily for 4 weeks produced a significant anti-wrinkle effect with 48.9% total efficacy and decreased skin roughness in Chinese subjects compared with 0% efficacy and no decrease in roughness in the placebo group. ([American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/))
- Treatment with cross-linked hyaluronic acid-based microneedle patches combined with acetyl hexapeptide-8 or epidermal growth factor significantly improved wrinkles and skin hydration compared to the patch alone in Korean females over 29 days. ([Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/))
- Acetyl hexapeptide-3 and tripeptide-10 citrulline demonstrated antiwrinkle efficacy and decreased transepidermal water loss in twenty-four healthy volunteers compared to control groups, though synergistic effects between the two peptides remained unclear. ([Journal of Cosmetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28150423/))
- Daily topical acetyl hexapeptide-8 showed a trend toward a longer time until return to baseline Jankovic Blepharospasm Rating Scale scores compared to placebo (3.7 months vs. 3.0 months) in 24 patients with blepharospasm receiving botulinum toxin therapy. ([European Journal of Neurology, 2013](https://pubmed.ncbi.nlm.nih.gov/23146065/))
- Argireline applied twice daily for 4 weeks achieved a total anti-wrinkle efficiency of 48.9% and notably reduced wrinkle depth compared to placebo in Chinese subjects. ([Journal of Cosmetic and Laser Therapy, 2013](https://pubmed.ncbi.nlm.nih.gov/23607739/))
- A multi-modal methodology combining MALDI-MSI, in vivo RCM, echography, and histology revealed age-related decreases in extracellular matrix and epidermal-dermal junction proteins and undulation depth, while a blend of palmitoyl oligopeptide and palmitoyl tetrapeptide-7 improved subepidermal low-echogenic band thickness, density, and extracellular matrix structure compared to placebo. ([Journal of Cosmetic Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25817264/))
- Palmitoyl hexapeptide-12 permeates the stratum corneum and epidermis, initiating gel formation via endogenous ions and strengthening and repairing the skin barrier after delipidation in human skin. ([ACS Applied Bio Materials, 2025](https://pubmed.ncbi.nlm.nih.gov/39964201/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))

## Why other moisturizers fit sensitive skin better

- A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38366684/))
- A topical microemulsion containing Punica granatum extract significantly reduced skin erythema and melanin compared to a placebo in healthy Asian subjects over 12 weeks. ([Postepy Dermatologii I Alergologii, 2014](https://pubmed.ncbi.nlm.nih.gov/25610348/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))

## What reviewers say

This serum-gel primer is highly praised for its hydrating, plumping, and smoothing effects, making it an excellent choice for mature skin or those seeking a radiant, dewy finish. While it excels at creating a smooth, makeup-ready canvas, some users find the packaging frustrating and the price point high for the amount of product provided.

- Liked: Intense hydration (often mentioned)
- Liked: Radiant finish (often mentioned)
- Liked: Makeup-gripping base (sometimes noted)
- Liked: Smooths fine lines (sometimes noted)
- Disliked: High price/value (sometimes noted)
- Disliked: Poor packaging (sometimes noted)
- Disliked: Heavy/comedogenic concerns (rarely noted)

## How to apply

- Use this soothing AM and PM routine every day to keep your normal skin calm. Always remember to apply SPF in the morning after your moisturizer.
- Apply your moisturizer after your toner in the morning, and after your serum in the evening. This step locks in hydration and protects your skin.
- Gently press a small amount of the moisturizer evenly across your face. Avoid rubbing to keep your sensitive skin happy and calm.
- You can apply this gentle formula on dry or slightly damp skin for the best comfort. It works wonderfully on clean skin to soothe redness and irritation.
- Do a patch test before your very first use to check your skin's reaction. Avoid getting the product directly into your eyes .
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does Estée Lauder Futurist Peptide-Power Serum Primer work for sensitive skin?

Estée Lauder Futurist Peptide-Power Serum Primer works decently for sensitive skin, as it lacks harsh ingredients and safely offers moderate hydration and plumping with glycerin and sodium hyaluronate. However, it does not specifically target redness and irritation, so a moisturizing treatment for sensitive skin needs ingredients that soothe irritation and reduce redness while providing deep hydration.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this serum a good fit for sensitive skin?

Glycerin and sodium hyaluronate make this serum a good fit for sensitive skin by helping keep it hydrated and soft, while whey protein provides a soothing feel. This product type needs ingredients that calm redness and irritation without causing irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Argireline do for sensitive skin?

Argireline is unlikely to cause irritation and is sometimes found in products designed to calm reactive skin. Studies show it helps smooth the look of wrinkles and decrease skin roughness when used consistently.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/), [Pharmaceuticals, 2021](https://pubmed.ncbi.nlm.nih.gov/34451799/)

### What does Palmitoyl Hexapeptide-12 do for sensitive skin?

Palmitoyl Hexapeptide-12 helps strengthen and repair the skin barrier for sensitive skin by working deep within the outer skin layers. This ingredient may improve your skin's overall comfort and resilience, making it feel less fragile and better protected against daily dryness and irritation.
Sources: [ACS Applied Bio Materials, 2025](https://pubmed.ncbi.nlm.nih.gov/39964201/)

### Where does this serum go in a skincare routine for sensitive skin?

This treatment goes in the evening routine after cleansing and toning, and before moisturizing. A product of this type for sensitive skin needs calming ingredients and gentle hydration that specifically target redness and irritation.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum before your retinol product to help keep your skin soft and comfortable. This type of product works best for sensitive skin when it includes soothing ingredients and gentle hydrators that calm redness and irritation.

### How often should I use this serum?

This treatment is suitable for your sensitive skin in the evening routine. To care for sensitive skin that experiences redness, this product needs calming ingredients that target irritation.

### Can this serum clog pores, cause breakouts or purging for sensitive skin?

This serum is unlikely to clog pores or cause breakouts for sensitive skin, as heavy or pore-clogging concerns are low for this formula. It provides gentle hydration and smoothing benefits, but a product for sensitive skin also needs ingredients that specifically target redness and irritation.

### Can I use this serum around the eyes or on my body?

This serum is safe to use around the eyes and on the body because it lacks harsh ingredients and includes soothing components. However, a product of this type needs extra soothing and calming ingredients to truly care for redness and irritation on sensitive skin.

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for sensitive skin

- [innisfree Green Tea Seed Hyaluronic Acid Hydrating Serum](https://lovi.care/skincare/ca/p/innisfree/green-tea-seed-hyaluronic-acid-hydrating-serum/for/sensitive-skin) — High fit — CA$40.50 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/ca/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — CA$44.95 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/ca/p/clarins/soothing-toning-lotion/for/sensitive-skin) — Superior fit — CA$49.00 at Amazon
- Moisturizer with Sun Protection: [Torriden DIVE-IN Mild Sunscreen](https://lovi.care/skincare/ca/p/torriden/dive-in-mild-sunscreen/for/sensitive-skin) — Superior fit — CA$27.34 at Amazon

## Where to buy

No store in Canada has a checked price for this product, so the page shows none.

## Ingredients

Water, Butylene Glycol, Glycerin, Acetyl Hexapeptide-8, Palmitoyl Hexapeptide-12, Sodium Pca, Whey Lactis Proteine Du Petit-Lait Protein, Glycine Soja Protein Soybean Protein, Sodium Hyaluronate, Acetyl Glucosamine, Lactobacillus Ferment, Tetrahexyldecyl Ascorbate, Chlorella Vulgaris Extract, Algae Extract, Caprylyl Glycol, Caffeine, Hydrolyzed Rice Extract, Laminaria Digitata Extract, Glucose, Artemia Extract, Sucrose, Peg-8, Xanthan Gum, Sodium Polyacryloyldimethyl Taurate, Calcium Chloride, Glyceryl Polymethacrylate, Sodium Hydroxide, Propanediol, Bht, Tocopheryl Acetate, Disodium Edta, Silica, Phenoxyethanol, Potassium Sorbate, Chlorphenesin, Mica, Titanium Dioxide Ci 77891, Iron Oxides Ci 77492, Bismuth Oxychloride, Carmine
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/estee-lauder/futurist-peptide-power-serum-primer/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/estee-lauder/futurist-peptide-power-serum-primer/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/estee-lauder/futurist-peptide-power-serum-primer/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/estee-lauder/futurist-peptide-power-serum-primer/for/sensitive-skin
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- Netherlands: https://lovi.care/skincare/nl/p/estee-lauder/futurist-peptide-power-serum-primer/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/estee-lauder/futurist-peptide-power-serum-primer/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/estee-lauder/futurist-peptide-power-serum-primer/for/sensitive-skin (this page)
- Australia: https://lovi.care/skincare/au/p/estee-lauder/futurist-peptide-power-serum-primer/for/sensitive-skin
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- United Arab Emirates: https://lovi.care/skincare/ae/p/estee-lauder/futurist-peptide-power-serum-primer/for/sensitive-skin