# Dermol 500 Lotion for combination skin

**Lovi Fit: Caution fit for combination skin.**
Combination Skin Fit: Caution · Effectiveness: Average · Safety: Risky.

Page: https://lovi.care/skincare/ca/p/dermol/500-lotion/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Brand: [Dermol](https://lovi.care/skincare/ca/brands/dermol)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/ca/best/moisturizers)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A poor match for combination skin; the moisturizers alongside fit it better.

## Why this fit

- Offers moderate moisturizing for your combination skin due to liquid paraffin and isopropyl myristate, which hydrate the skin but may exacerbate oiliness and clog pores.
- The presence of Benzalkonium Chloride and Chlorhexidine Dihydrochloride provides antimicrobial benefits, offering moderate exfoliation for oily skin.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ca/p/dermol/500-lotion/for/oily-skin): Warning
- [Dry skin](https://lovi.care/skincare/ca/p/dermol/500-lotion/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/ca/p/dermol/500-lotion/for/combination-skin): Caution (this page)
- [Sensitive skin](https://lovi.care/skincare/ca/p/dermol/500-lotion/for/sensitive-skin): Caution
- [Acne-prone skin](https://lovi.care/skincare/ca/p/dermol/500-lotion/for/acne-prone-skin): Caution
- [Skin with dark spots](https://lovi.care/skincare/ca/p/dermol/500-lotion/for/dark-spots): Caution
- [Mature skin](https://lovi.care/skincare/ca/p/dermol/500-lotion/for/mature-skin): Caution
- [Dry sensitive skin](https://lovi.care/skincare/ca/p/dermol/500-lotion/for/dry-sensitive-skin): Low
- [Oily acne-prone skin](https://lovi.care/skincare/ca/p/dermol/500-lotion/for/oily-acne-prone-skin): Caution

## Key ingredients

Benzalkonium Chloride, Chlorhexidine Dihydrochloride, Liquid Paraffin, Isopropyl Myristate, Cetostearyl Alcohol

## What the research says

- Topical application of isopropyl palmitate, isopropyl myristate, butyl stearate, isopropyl isostearate, decyl oleate, isostearyl neopentanoate, isocetyl stearate, myristle myristate, and cocoa butter produced comedone formation in the rabbit external ear canal. ([Cutaneous and Ocular Toxicology, 2007](https://pubmed.ncbi.nlm.nih.gov/18058303/))
- A non-alcoholic benzalkonium chloride hand sanitizer demonstrated antibacterial activity against nine out of eleven bacterial strains and caused no skin irritation or redness in ten participants compared to alcohol-based hand gels. ([Saudi Pharmaceutical Journal, 2021](https://pubmed.ncbi.nlm.nih.gov/34408542/))
- Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016](https://pubmed.ncbi.nlm.nih.gov/27475700/))
- Topical application of an intimate cleansing gel containing chlorhexidine, hyaluronic acid, and anti-inflammatory agents after ultrasound scalpel-assisted hemorrhoidectomy reduced pain and itching while accelerating complete wound healing at 4 weeks compared to washing with warm water alone in adult patients. ([Annals of Coloproctology, 2024](https://pubmed.ncbi.nlm.nih.gov/39748553/))
- Topical therapy with 4% chlorhexidine digluconate products resolved clinical signs in all dogs with superficial pyoderma, including those with meticillin-resistant strains, showing comparable efficacy to systemic amoxicillin-clavulanic acid. ([Veterinary Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/26140535/))
- Repeated application of concentrated water-in-oil emulsions over four weeks caused no skin irritation, positively affected skin properties, and delivered almost 50% of the applied fluorescein sodium, with isopropyl myristate showing superior penetration performance compared to liquid paraffin in healthy volunteers. ([International Journal of Pharmaceutics, 2019](https://pubmed.ncbi.nlm.nih.gov/31525444/))
- Increasing the softness of pressure-sensitive adhesives using isopropyl myristate decreased pain and stripped corneocytes during removal without significantly changing human skin dermal peeling force. ([Skin Research and Technology, 2007](https://pubmed.ncbi.nlm.nih.gov/17374065/))
- A modern cold cream formulation using a self-emulsionable excipient with isopropyl myristate shows improved preparation ease, stability, rheological qualities, and moisture and emollient power compared to traditional cerates. ([Bollettino Chimico Farmaceutico, 1996](https://pubmed.ncbi.nlm.nih.gov/8942063/))

## What reviewers say

It is celebrated for its versatility as both a leave-on moisturizer and a soap substitute, providing rapid relief from itching and preventing secondary infections due to its antimicrobial properties.

- Liked: Versatile application (mostly mentioned)
- Liked: Excellent texture (often mentioned)
- Liked: Hand care (often mentioned)
- Liked: Rapid itch relief (often mentioned)
- Liked: Antimicrobial benefits (sometimes noted)
- Disliked: Adverse reactions (rarely noted)
- Disliked: Insufficient for dryness (rarely noted)
- Disliked: Medicinal scent (rarely noted)
- Disliked: Packaging issues (rarely noted)
- Disliked: Texture dislike (rarely noted)

## How to apply

- Use this moisturizer in your AM and PM routine every day to control shine. Always pair with SPF in the morning.
- Apply this moisturizer after your cleanser and toner, right before your morning SPF.
- Gently press a small amount of the moisturizer into your skin and avoid harsh rubbing. Let it ⏳absorb for a minute.
- Apply the moisturizer on slightly damp skin to help it lock in moisture better. This keeps your combination skin balanced.
- Avoid the eye area when applying the moisturizer. Do a patch test before your first use.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### Why does Lovi advise caution with Dermol 500 Lotion for combination skin?

This lotion may exacerbate oiliness and clog pores on combination skin because it contains liquid paraffin and isopropyl myristate. A product for this skin needs soothing and hydrating ingredients like aloe and Centella Asiatica that balance dry and oily areas without clogging pores.
Sources: [Cutaneous and Ocular Toxicology, 2007](https://pubmed.ncbi.nlm.nih.gov/18058303/)

### Which ingredients make this lotion a poor fit for combination skin?

Liquid paraffin and isopropyl myristate make this lotion a poor fit because they hydrate the skin but may increase oiliness and clog pores. A moisturizing treatment for combination skin needs soothing and hydrating ingredients like aloe and Centella Asiatica that balance dry and oily areas without clogging pores.
Sources: [Cutaneous and Ocular Toxicology, 2007](https://pubmed.ncbi.nlm.nih.gov/18058303/)

### What does Benzalkonium Chloride do for combination skin?

Benzalkonium chloride is unlikely to suit combination skin because it is a known skin irritant and allergen that may cause redness or rashes. A product for this skin needs gentle, soothing ingredients that calm irritation and protect the skin barrier.
Sources: [Dermatosen in Beruf und Umwelt. Occupation and Environment, 1985](https://pubmed.ncbi.nlm.nih.gov/4028973/)

### What does Chlorhexidine Dihydrochloride do for combination skin?

Chlorhexidine Dihydrochloride is an antiseptic that helps reduce bacteria on the skin, but a product for combination skin also needs balanced hydrators and lightweight ingredients that care for both dry and oily areas without clogging pores.
Sources: [MSphere, 2025](https://pubmed.ncbi.nlm.nih.gov/40874607/), [The Journal of Investigative Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29753031/)

### Where does this lotion go in a skincare routine for combination skin?

This lotion may not be the best fit for your combination skin because its heavy ingredients can increase oiliness and clog pores. To properly care for combination skin, a moisturizer needs lightweight hydrators that balance moisture without feeling heavy or causing breakouts.
Sources: [Cutaneous and Ocular Toxicology, 2007](https://pubmed.ncbi.nlm.nih.gov/18058303/)

### Can I use it with retinol, and in what order?

You should exercise caution when using this lotion with retinol on combination skin, as its heavy ingredients may clog pores and increase oiliness in certain areas. To care for combination skin properly, you instead need a lightweight moisturizer with ceramides and soothing ingredients that hydrates dry zones without triggering breakouts.
Sources: [Cutaneous and Ocular Toxicology, 2007](https://pubmed.ncbi.nlm.nih.gov/18058303/), [Journal of Drugs in Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37276158/)

### How often should I use this lotion?

This lotion is a poor match for combination skin because its heavy oils may make oily areas slicker and clog pores. To properly care for combination skin, a moisturizer needs light, oil-free hydrators that soften the skin without adding extra shine or clogging pores.

### Can it clog pores, cause breakouts or purging for combination skin?

Yes, this lotion may clog pores and cause breakouts on combination skin because ingredients like isopropyl myristate and liquid paraffin tend to trap oil in the skin. To care for combination skin safely, a product of this type needs lightweight hydrators and non-pore-clogging ingredients that balance dry areas without making oily zones greasy.
Sources: [Cutaneous and Ocular Toxicology, 2007](https://pubmed.ncbi.nlm.nih.gov/18058303/)

### Can I use this lotion around the eyes or on my body?

This lotion is a poor match for your combination skin because its heavier oils may clog pores and increase oiliness. For the thin skin around the eyes and on the body, a moisturizing treatment of this type needs lightweight hydrators and gentle, non-clogging ingredients that nourish without feeling heavy.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/), [Cutaneous and Ocular Toxicology, 2007](https://pubmed.ncbi.nlm.nih.gov/18058303/)

### Is it fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for combination skin

- [VT COSMETICS Cica Skin](https://lovi.care/skincare/ca/p/vt-cosmetics/cica-skin/for/combination-skin) — High fit — CA$29.17 at Amazon
- [ROUND LAB Mugwort Calming Line](https://lovi.care/skincare/ca/p/round-lab/mugwort-calming-line/for/combination-skin) — High fit — CA$20.24 at Amazon

## Routine for combination skin

### AM

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/ca/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — CA$44.95 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/ca/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — CA$37.60 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/ca/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/combination-skin) — Superior fit — CA$29.98 at Amazon
- SPF: [CeraVe AM Facial Moisturizing Lotion](https://lovi.care/skincare/ca/p/cerave/am-facial-moisturizing-lotion-spf-30/for/combination-skin) — Superior fit — CA$20.96 at Amazon

### PM

- Pre-Cleanser: [Pyunkang Yul Deep Cleansing Oil](https://lovi.care/skincare/ca/p/pyunkang-yul/deep-cleansing-oil/for/combination-skin) — Superior fit — CA$23.99 at Amazon
- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/ca/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — CA$44.95 at Amazon
- Cleansing Toner: [Medicube Zero Pore Pad 2.0](https://lovi.care/skincare/ca/p/medicube/zero-pore-pad-2-0/for/combination-skin) — Superior fit — CA$31.99 at Amazon
- Serum or Treatment: [The Ordinary Niacinamide 10% + Zinc 1%](https://lovi.care/skincare/ca/p/the-ordinary/niacinamide-10-zinc-1/for/combination-skin) — Superior fit — CA$6.60 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/ca/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/combination-skin) — Superior fit — CA$29.98 at Amazon

### Weekly

- Pre-Cleanser: [Pyunkang Yul Deep Cleansing Oil](https://lovi.care/skincare/ca/p/pyunkang-yul/deep-cleansing-oil/for/combination-skin) — Superior fit — CA$23.99 at Amazon
- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/ca/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — CA$44.95 at Amazon
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/ca/p/dermalogica/daily-microfoliant/for/combination-skin) — Superior fit — CA$29.50 at Amazon
- Cleansing Mask: [Origins Original Skin Retexturizing Mask with Rose Clay](https://lovi.care/skincare/ca/p/origins/original-skin-retexturizing-mask-with-rose-clay/for/combination-skin) — Superior fit — CA$50.00 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/ca/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — CA$37.60 at Amazon
- Serum or Treatment: [The Ordinary Niacinamide 10% + Zinc 1%](https://lovi.care/skincare/ca/p/the-ordinary/niacinamide-10-zinc-1/for/combination-skin) — Superior fit — CA$6.60 at Amazon

## Where to buy

No store in Canada has a checked price for this product, so the page shows none.

## Ingredients

Benzalkonium Chloride, Chlorhexidine Dihydrochloride, Liquid Paraffin, Isopropyl Myristate, Cetostearyl Alcohol, Cetomacrogol 1000, Phenoxyethanol, Water
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/dermol/500-lotion/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/dermol/500-lotion/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/dermol/500-lotion/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/dermol/500-lotion/for/combination-skin
- France: https://lovi.care/skincare/fr/p/dermol/500-lotion/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/dermol/500-lotion/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/dermol/500-lotion/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/dermol/500-lotion/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/dermol/500-lotion/for/combination-skin (this page)
- Australia: https://lovi.care/skincare/au/p/dermol/500-lotion/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/dermol/500-lotion/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/dermol/500-lotion/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/dermol/500-lotion/for/combination-skin