Dermol 500 Lotion for acne-prone skin

Caution
- CautionCombination Skin Fit
- AverageEffectiveness
- RiskySafety
A poor match for acne-prone skin; the moisturizers alongside fit it better.
This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate moisturizing for your combination skin due to liquid paraffin and isopropyl myristate, which hydrate and soften but may clog pores and exacerbate oiliness.
- The antiseptic properties of Benzalkonium Chloride and Chlorhexidine Dihydrochloride provide some benefit for acne and blemishes, though they are not specialized enough to significantly combat breakouts.
How to apply
- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help keep breakouts under control.
- Apply after your cleanser and toner, and make sure to use your SPF right after in the morning.
- Gently spread a small amount of moisturizer over your face using soft motions. Let it absorb into the skin for a minute before getting dressed or applying makeup.
- Apply on slightly damp skin to help lock in extra moisture. This keeps your combination skin balanced without feeling heavy.
- Avoid the eye area and do a patch test before your first use. Stop using if you feel any irritation.
People Say
★4.9Overall rating based on 1000+ reviewsIt is celebrated for its versatility as both a leave-on moisturizer and a soap substitute, providing rapid relief from itching and preventing secondary infections due to its antimicrobial properties.
Highlights
Versatile application Mostly Mentioned
- “Soap substitute”
- “shower gel”
- “leave-on moisturizer”
Excellent texture Often Mentioned
- “Non-greasy”
- “absorbs quickly”
- “light consistency”
Hand care Often Mentioned
- “Heals cracked hands”
- “non-drying wash”
- “gentle cleanser”
Rapid itch relief Often Mentioned
- “Soothes irritation”
- “stops scratching”
- “calms redness”
Antimicrobial benefits Sometimes Noted
- “Prevents infection”
- “clears folliculitis”
- “kills bacteria”
Adverse reactions Rarely Noted
- “Facial rash”
- “stinging sensation”
- “increased redness”
Insufficient for dryness Rarely Noted
- “Too thin”
- “not rich enough”
- “requires thicker cream”
Medicinal scent Rarely Noted
- “Weird smell”
- “chemical odor”
- “unpleasant scent”
Packaging issues Rarely Noted
- “Pump faults”
- “hard to empty”
- “broken dispenser”
Texture dislike Rarely Noted
- “Too runny”
- “watery consistency”
- “not lotion-like”
Sources: lovi.care, pharmica.co.uk, medino.com, chemist-4-u.com, amazon.com, chemistdirect.co.uk, and more
Questions and answers
Why does Lovi advise caution with Dermol 500 Lotion for acne-prone skin?
Lovi advises caution because the liquid paraffin and isopropyl myristate in this lotion hydrate and soften the skin, but they may also clog pores and make oiliness worse. A moisturizing treatment for acne-prone skin needs lightweight, non-clogging hydrating ingredients that provide moisture without blocking pores, along with soothing agents to calm breakouts without causing irritation.
Which ingredients make this lotion a poor fit for acne-prone skin?
Isopropyl myristate and liquid paraffin make this lotion a poor fit because they may clog pores and increase oiliness on acne-prone skin. A product of this type needs non-clogging, soothing hydrators and targeted ingredients that balance oil without triggering breakouts.
What does Benzalkonium Chloride do for acne-prone skin?
Benzalkonium chloride helps fight bacteria on the skin, but it may cause irritation or redness if your skin is sensitive. A product of this type needs soothing ingredients and gentle hydrators to keep acne-prone skin calm and smooth.
What does Chlorhexidine Dihydrochloride do for acne-prone skin?
Chlorhexidine Dihydrochloride helps acne-prone skin by significantly reducing inflamed bumps like papules and pustules. It acts as an antiseptic to lower bacteria on the skin, though rare allergic reactions like severe skin sensitivity or shock may occur.
Where does this lotion go in a skincare routine for acne-prone skin?
This lotion is a poor match for acne-prone skin because heavy ingredients like liquid paraffin and isopropyl myristate may clog pores and make oiliness worse. Acne-prone skin needs lightweight, oil-free moisturizers that hydrate without blocking pores, along with specialized blemish-fighting ingredients.
Can I use this lotion with retinol, and in what order?
Exercise caution when using this lotion alongside retinol on acne-prone skin, as heavy ingredients like liquid paraffin and isopropyl myristate may clog pores and worsen breakouts. To properly care for this skin type, look for lightweight, non-clogging moisturizers containing soothing ingredients like ceramides or licochalcone that hydrate without adding excess oil.
How often should I use this lotion?
This moisturizing treatment is a poor match for acne-prone skin because its ingredients may clog pores and increase oiliness. Acne-prone skin needs lightweight, oil-free hydration and targeted breakout-fighting ingredients instead.
Can this lotion clog pores, cause breakouts or purging for acne-prone skin?
This lotion may clog pores and increase oiliness because it contains ingredients like liquid paraffin and isopropyl myristate that can trap debris in your skin. Acne-prone skin needs lightweight, oil-free hydration and targeted blemish-fighting ingredients instead of heavy, pore-clogging oils.
Can I use this lotion around the eyes or on my body?
This lotion is unlikely to suit the thin skin around the eyes because heavy ingredients like liquid paraffin and isopropyl myristate may clog pores and cause irritation in delicate areas. For the body, this type of moisturizing treatment needs soothing hydrators and lightweight oils that soften dry skin without feeling heavy or greasy.
Surgical and Radiologic Anatomy, 2002Cutaneous and Ocular Toxicology, 2007
Is this lotion fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
Topical application of isopropyl palmitate, isopropyl myristate, butyl stearate, isopropyl isostearate, decyl oleate, isostearyl neopentanoate, isocetyl stearate, myristle myristate, and cocoa butter produced comedone formation in the rabbit external ear canal.
Cutaneous and Ocular Toxicology, 2007A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo.
Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel.
Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016Topical application of an intimate cleansing gel containing chlorhexidine, hyaluronic acid, and anti-inflammatory agents after ultrasound scalpel-assisted hemorrhoidectomy reduced pain and itching while accelerating complete wound healing at 4 weeks compared to washing with warm water alone in adult patients.
Annals of Coloproctology, 2024Topical therapy with 4% chlorhexidine digluconate products resolved clinical signs in all dogs with superficial pyoderma, including those with meticillin-resistant strains, showing comparable efficacy to systemic amoxicillin-clavulanic acid.
Veterinary Dermatology, 2015Repeated application of concentrated water-in-oil emulsions over four weeks caused no skin irritation, positively affected skin properties, and delivered almost 50% of the applied fluorescein sodium, with isopropyl myristate showing superior penetration performance compared to liquid paraffin in healthy volunteers.
International Journal of Pharmaceutics, 2019Increasing the softness of pressure-sensitive adhesives using isopropyl myristate decreased pain and stripped corneocytes during removal without significantly changing human skin dermal peeling force.
Skin Research and Technology, 2007A modern cold cream formulation using a self-emulsionable excipient with isopropyl myristate shows improved preparation ease, stability, rheological qualities, and moisture and emollient power compared to traditional cerates.
Bollettino Chimico Farmaceutico, 1996
Ingredients
Benzalkonium Chloride, Chlorhexidine Dihydrochloride, Liquid Paraffin, Isopropyl Myristate, Cetostearyl Alcohol, Cetomacrogol 1000, Phenoxyethanol, Water
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
-

Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
-

Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
-

Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
-

Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
-

Medical Board
Cosmetic chemist, SCS, IFSCC member
-

Medical Board, Medical Advisor
Dermatology MD
-

Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
-

Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
Scan your face, then any product: Lovi shows how well it fits you and what fits even better.