# Derma E Pure Biome Balancing Cleanser for sensitive skin

**Lovi Fit: High fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/ca/p/derma-e/pure-biome-balancing-cleanser/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Brand: [Derma E](https://lovi.care/skincare/ca/brands/derma-e)
Category: [Cleansers](https://lovi.care/skincare/ca/best/cleansers)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for sensitive skin; a few cleansers fit it even better.

## Why this fit

- Highly suitable for your normal skin, this cleanser effectively addresses redness and irritation with Centella Asiatica and Chamomilla Recutita Flower Extract providing targeted soothing and anti-inflammatory effects.
- The inclusion of decyl glucoside and glycerin ensures excellent cleansing and hydration, complementing the calming ingredients for overall skin comfort.
- The formulation is safe for your sensitive skin, as it lacks any harsh or prohibited ingredients that could cause irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ca/p/derma-e/pure-biome-balancing-cleanser/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/ca/p/derma-e/pure-biome-balancing-cleanser/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/ca/p/derma-e/pure-biome-balancing-cleanser/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/ca/p/derma-e/pure-biome-balancing-cleanser/for/sensitive-skin): High (this page)
- [Acne-prone skin](https://lovi.care/skincare/ca/p/derma-e/pure-biome-balancing-cleanser/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/ca/p/derma-e/pure-biome-balancing-cleanser/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/ca/p/derma-e/pure-biome-balancing-cleanser/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/ca/p/derma-e/pure-biome-balancing-cleanser/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/ca/p/derma-e/pure-biome-balancing-cleanser/for/oily-acne-prone-skin): High

## Key ingredients

Centella Asiatica Cell Culture Meristem Cell Culture, Lactobacillus Panax Ginseng Root Extract Ferment Filtrate, Camellia Sinensis Leaf Extract, Glycerin, Allantoin

## What the research says

- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Enzyme-modified ginseng extract cream significantly reduced the global photo-damage score and various roughness measures including total roughness, smoothness depth, and arithmetic roughness average compared to placebo in 23 human subjects. ([Rejuvenation Research, 2015](https://pubmed.ncbi.nlm.nih.gov/25867599/))
- A red ginseng hydrogel formulation with 1,2-hexanediol promoted selective growth of Staphylococcus epidermidis and decreased Cutibacterium acnes in 20 female subjects. ([Journal of Ginseng Research, 2022](https://pubmed.ncbi.nlm.nih.gov/35509819/))
- A 1% fermented black ginseng cream significantly reduced eye wrinkles and brightened skin color in twenty-three human subjects compared to control cream and baseline. ([Journal of Toxicology and Environmental Health. Part A, 2020](https://pubmed.ncbi.nlm.nih.gov/32564709/))
- Topical green tea extract significantly improved clinical symptoms, tear breakup times, and meibomian gland health compared to standard treatment in patients with dry eye and Meibomian Gland Dysfunction. ([Journal of Clinical and Diagnostic Research, 2017](https://pubmed.ncbi.nlm.nih.gov/28384900/))
- Topical low-dose green tea extract reduces UVB-induced p53 expression and apoptosis in human skin keratinocytes compared to placebo. ([Experimental Dermatology, 2009](https://pubmed.ncbi.nlm.nih.gov/18631247/))
- An anti-acne hydrogel containing Aloe barbadensis, Garcinia mangostana, and Camellia sinensis extracts showed superior antiacne and antiblotch activities compared to 1% clindamycin gel in sixty subjects with mild-moderate acne. ([Clinical, Cosmetic and Investigational Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/31239743/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016](https://pubmed.ncbi.nlm.nih.gov/27475700/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment. ([Aesthetic Plastic Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29948103/))

## What reviewers say

This sulfate-free gel cleanser is highly praised by users with sensitive and reactive skin for its ability to clean effectively without causing dryness or irritation. While it is celebrated for calming redness and maintaining skin balance, some users remain skeptical about the actual impact of its prebiotic/postbiotic ingredients given the short contact time during washing.

- Liked: Gentle on skin (often mentioned)
- Liked: Non-stripping formula (often mentioned)
- Liked: Calms redness/irritation (sometimes noted)
- Liked: Fragrance-free (sometimes noted)
- Disliked: Potential for sensitivity (rarely noted)
- Disliked: Questionable biome claims (rarely noted)
- Disliked: Scent formula changes (rarely noted)

## How to apply

- Use your cleanser in the AM and PM routines every day. Start using it daily since your sensitive skin needs gentle care.
- Apply this first in your morning and evening skincare routine before toner and moisturizer. This clears away dirt without upsetting your skin.
- Gently massage a small amount onto your face using soft circles. Avoid any rough rubbing to keep redness away.
- Apply the cleanser on slightly damp skin to help it wash away impurities softly. Clean skin feels fresh and comfortable afterwards.
- Avoid getting the cleanser in your eyes and do a quick patch test before first use. Rinse thoroughly with lukewarm water.
- Video: https://storage.pora.ai/6a08416bd9315041c09c72f61cf27cc1.mp4

## Questions and answers

### What makes DERMA E Pure Biome Balancing Cleanser a great fit for sensitive skin?

This cleanser is a great fit because it uses centella asiatica and chamomile to calm redness and irritation on sensitive skin. It also includes gentle cleansers and glycerin to clean your skin while keeping it comfortable and hydrated without harsh ingredients.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this cleanser a good fit for sensitive skin?

This cleanser is a great fit for sensitive skin because it contains Centella asiatica and chamomile flower extract, which help soothe redness and irritation. It also includes glycerin and decyl glucoside for gentle cleansing and hydration, while leaving out harsh ingredients that could upset your skin.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Centella Asiatica do for sensitive skin?

Centella asiatica helps calm sensitive skin and keeps it feeling soft by soothing irritation and supporting the skin barrier. It is unlikely to cause trouble and may help reduce redness and discomfort over a few weeks of regular use.
Sources: [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40682399/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### What does Lactobacillus Ferment do for sensitive skin?

Lactobacillus Ferment helps calm sensitive skin by reducing redness, decreasing water loss, and boosting overall moisture. It may also strengthen the skin barrier and lower skin reactivity against outside irritation.
Sources: [Scientific Reports, 2023](https://pubmed.ncbi.nlm.nih.gov/37803101/), [Experimental Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/19624730/)

### Where does this cleanser go in a skincare routine for sensitive skin?

This cleanser is used both in the morning and evening as part of a daily routine for sensitive skin. It gently washes the face while helping to calm redness and irritation without harsh ingredients.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Can I use this cleanser with retinol, and in what order?

Yes, you can use this cleanser with retinol as part of your routine. Apply the cleanser first to gently wash your face, and follow it with your retinol treatment.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use this cleanser?

You can use this cleanser twice a day in your morning and evening routine. It is a great fit for sensitive skin because it gently washes and hydrates without harsh ingredients that cause irritation.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/)

### Can this cleanser clog pores, cause breakouts or purging for sensitive skin?

This cleanser is unlikely to clog pores or cause breakouts for sensitive skin because it lacks harsh ingredients and uses gentle, calming components like Centella Asiatica and glycerin. It has a negligible potential for sensitivity and helps keep skin calm and hydrated without heavy oils that typically block pores.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Can I use this cleanser around the eyes or on my body?

Yes, you can use this gentle cleanser on your body and around your eyes. Its safe formula leaves sensitive skin feeling clean and comfortable without irritation.

### Is this cleanser fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Stearyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for sensitive skin

- [La Roche-Posay Hydrating Gentle Cleanser](https://lovi.care/skincare/ca/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/sensitive-skin) — Superior fit — CA$30.56 at Amazon
- [Cetaphil Gentle Foaming Cleanser](https://lovi.care/skincare/ca/p/cetaphil/gentle-foaming-cleanser/for/sensitive-skin) — Superior fit — CA$16.96 at Amazon
- [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/ca/p/cerave/foaming-facial-cleanser/for/sensitive-skin) — Superior fit — CA$20.96 at Amazon

## Pairs well with

- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/ca/p/clarins/soothing-toning-lotion/for/sensitive-skin) — Superior fit — CA$49.00 at Amazon
- Moisturizer with Sun Protection: [Torriden DIVE-IN Mild Sunscreen](https://lovi.care/skincare/ca/p/torriden/dive-in-mild-sunscreen/for/sensitive-skin) — Superior fit — CA$27.34 at Amazon
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/ca/p/missha/ultra-hyalon-cleansing-cream/for/sensitive-skin) — Superior fit — CA$17.99 at Amazon

## Where to buy

No store in Canada has a checked price for this product, so the page shows none.

## Ingredients

Water, Glycerin, Decyl Glucoside, Stearyl Alcohol, Panthenol, Centella Asiatica Cell Culture Meristem Cell Culture, Inulin, Ganoderma Lucidum Extract Mushroom Extract, Lactobacillus Panax Ginseng Root Extract Ferment Filtrate, Xanthophyll Lutein, Cucumis Sativus Fruit Extract, Panax Quinquefolius Root Extract Panax Ginseng Root Extract, Camellia Sinensis Leaf Extract, Chamomilla Recutita Flower Extract Matricaria Flower Extract, Ombopogon Schoenanthus Extract, Allantoin, Aloe Barbadensis Leaf Juice, Pinus Pinaster Bark Extract, Glyceryl Stearate Citrate, Xanthan Gum, Sucrose, Tapioca Starch, Potassium Sorbate, Phenoxyethanol, Ethylhexylglycerin
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/derma-e/pure-biome-balancing-cleanser/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/derma-e/pure-biome-balancing-cleanser/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/derma-e/pure-biome-balancing-cleanser/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/derma-e/pure-biome-balancing-cleanser/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/derma-e/pure-biome-balancing-cleanser/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/derma-e/pure-biome-balancing-cleanser/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/derma-e/pure-biome-balancing-cleanser/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/derma-e/pure-biome-balancing-cleanser/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/derma-e/pure-biome-balancing-cleanser/for/sensitive-skin (this page)
- Australia: https://lovi.care/skincare/au/p/derma-e/pure-biome-balancing-cleanser/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/derma-e/pure-biome-balancing-cleanser/for/sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/derma-e/pure-biome-balancing-cleanser/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/derma-e/pure-biome-balancing-cleanser/for/sensitive-skin