# Derma E Anti-Wrinkle Cleanser for acne-prone skin

**Lovi Fit: Average fit for acne-prone skin.**
Combination Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/ca/p/derma-e/anti-wrinkle-cleanser/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Brand: [Derma E](https://lovi.care/skincare/ca/brands/derma-e)
Category: [Cleansers](https://lovi.care/skincare/ca/best/cleansers)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for acne-prone skin; other cleansers fit it better.

## Why this fit

- Offers moderate exfoliation and smoothing for your combination skin due to glycolic acid and bakuchiol, which promote skin renewal but lack sufficient hydrating ingredients for drier areas.
- While it provides general skincare benefits, the formula does not contain targeted ingredients to address your acne, blemishes, and breakouts effectively.
- The product is safe for your combination skin as it lacks prohibited or harsh ingredients that could cause irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ca/p/derma-e/anti-wrinkle-cleanser/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/ca/p/derma-e/anti-wrinkle-cleanser/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/ca/p/derma-e/anti-wrinkle-cleanser/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/ca/p/derma-e/anti-wrinkle-cleanser/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/ca/p/derma-e/anti-wrinkle-cleanser/for/acne-prone-skin): Average (this page)
- [Skin with dark spots](https://lovi.care/skincare/ca/p/derma-e/anti-wrinkle-cleanser/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/ca/p/derma-e/anti-wrinkle-cleanser/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/ca/p/derma-e/anti-wrinkle-cleanser/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/ca/p/derma-e/anti-wrinkle-cleanser/for/oily-acne-prone-skin): Average

## Key ingredients

Vitamin A, Glycolic Acid, Bakuchiol, Retinol, Carica Papaya Fruit Extract

## What the research says

- Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging. ([The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/))
- A dermocosmetic containing bakuchiol, Ginkgo biloba extract, and mannitol improves inflammatory lesions, Investigator Global Assessment, and seborrhea intensity when added to adapalene 0.1% gel in patients with acne vulgaris. ([Clinical, Cosmetic and Investigational Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25914553/))
- Over-the-counter retinol products provided only weak evidence for a mild ameliorating effect on fine facial skin wrinkle lines in randomized, double-blind, vehicle-controlled trials, and major methodological flaws call the validity of positive results into question. ([The Journal of Clinical and Aesthetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/34980969/))
- A cosmetic niacinamide/peptide/retinyl propionate regimen significantly improved periorbital wrinkle appearance relative to a 0.02% tretinoin regimen at 8 weeks with comparable benefits at 24 weeks, while demonstrating significantly better tolerability in 196 women. ([The British Journal of Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/20374604/))
- A novel triple-active cosmetic formulation containing 4-hexylresorcinol, retinyl propionate, and niacinamide improved the visual appearance of photoageing similarly to 0.02% tretinoin and reversed a consensus gene signature associated with ageing in female adults while causing less skin irritation. ([International Journal of Cosmetic Science, 2024](https://pubmed.ncbi.nlm.nih.gov/38685700/))
- Repeated short-contact 70% glycolic acid peels provided superior results in atrophic acne scars compared to daily low-strength glycolic acid cream or placebo in 58 women over 24 weeks. ([International Journal of Dermatology, 2000](https://pubmed.ncbi.nlm.nih.gov/11095203/))
- Serial glycolic acid peels combined with a modified Kligman formula significantly reduced facial PIH severity in Indian patients compared to the modified Kligman formula alone. ([Dermatologic Surgery, 2017](https://pubmed.ncbi.nlm.nih.gov/28114204/))
- Topical application of a serum containing supramolecular Bakuchiol and Terminalia chebula extract significantly improved barrier function, reduced redness and sensitivity, and improved wrinkles and elasticity in 34 Chinese subjects with sensitive skin after 28 days. ([Health Science Reports, 2025](https://pubmed.ncbi.nlm.nih.gov/41424674/))
- Bakuchiol functions as an anti-aging compound through retinol-like regulation of gene expression, producing significant improvements in lines, wrinkles, pigmentation, elasticity, firmness, and photo-damage after 12 weeks of twice-a-day facial application without usual retinol therapy-associated undesirable effects. ([International Journal of Cosmetic Science, 2014](https://pubmed.ncbi.nlm.nih.gov/24471735/))
- A nature-based bakuchiol-containing cleanser and moisturizer improved visual and tactile smoothness, clarity, radiance, overall appearance, global anti-aging, and skin moisture content by 16% in 60 female subjects with sensitive mild to moderate photodamaged skin over 4 weeks. ([Journal of Drugs in Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/33346506/))
- Topical 0.4% retinol significantly increased epidermal thickness, dermal vascularity, and extracellular matrix production by stimulating keratinocyte proliferation, endothelial cell proliferation, and fibroblast activation in naturally aged human skin compared to vehicle. ([International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/))
- Silicone particles encapsulating retinol increased its half-life by 9-fold and yielded 12-23% lower skin irritation in human subjects compared to Microsponge particles while maintaining biological activity. ([Journal of Controlled Release, 2018](https://pubmed.ncbi.nlm.nih.gov/29604311/))
- Topical stabilized retinol treatment induced HAS gene expression and increased hyaluronic acid production in human skin in vitro, ex vivo, and in vivo compared to vehicle. ([Archives of Dermatological Research, 2017](https://pubmed.ncbi.nlm.nih.gov/28247017/))
- Topical papain treatment may slightly decrease pain within 30 minutes in humans stung by Chrysaora chinensis compared to placebo. ([Wilderness & Environmental Medicine, 2016](https://pubmed.ncbi.nlm.nih.gov/26827260/))
- A fixed combination of hydroxypinacolone retinoate, retinol glycospheres, and papain glycospheres in aqueous gel applied once daily for 12 weeks achieved a 41% mean reduction in GAGS score and a 40.8% mean reduction in total lesions, with 15.3% of patients experiencing mild to moderate local side effects, in 94 evaluable patients with comedonal-papular, mild to moderate acne of the face. ([Giornale Italiano Di Dermatologia E Venereologia, 2015](https://pubmed.ncbi.nlm.nih.gov/25876142/))
- Reflux extraction of Carica papaya leaves yielded higher antioxidant capacity and superior in vitro wound-healing activities including fibroblast proliferation, cell migration, and collagen synthesis in human skin fibroblasts compared to ultrasonic-assisted extraction and agitation. ([Molecules, 2020](https://pubmed.ncbi.nlm.nih.gov/31991676/))

## Why other cleansers fit acne-prone skin better

- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38366684/))

## What reviewers say

This cleanser is widely praised for its effective makeup removal and ability to leave skin feeling clean and smooth without excessive dryness. While it is a favorite for many seeking a budget-friendly, cruelty-free option for daily use, individuals with sensitive skin or specific skin conditions should be mindful of its exfoliating ingredients, which can occasionally lead to redness or irritation. This summary is based on a very large amount of data and should definitely be taken into account.

- Liked: Effective makeup removal (mostly mentioned)
- Liked: Gentle daily use (often mentioned)
- Liked: Non-stripping formula (often mentioned)
- Liked: Good value (sometimes noted)
- Disliked: Potential irritation (sometimes noted)
- Disliked: Ineffective for some (rarely noted)
- Disliked: Scent concerns (rarely noted)

## How to apply

- Could be used as part of your AM and PM routine. Start using it 3 times a week and build up to daily use if your skin tolerates it.
- This cleanser is the first step in your morning routine and the second step after your pre-cleanser in the evening. Always follow up with a toner and moisturizer .
- Gently massage a small amount of the cleanser onto your face in circular motions. Avoid harsh rubbing to keep your skin calm.
- Apply the cleanser on slightly damp skin to help it work effectively against breakouts. Rinse thoroughly with lukewarm water .
- Avoid the immediate eye area and do a patch test before your first use to check for any sensitivity.
- Video: https://storage.pora.ai/6a08416bd9315041c09c72f61cf27cc1.mp4

## Questions and answers

### How well does Derma E Anti-Wrinkle Cleanser work for acne-prone skin?

This cleanser works moderately well for acne-prone skin, though other products fit it better because it lacks targeted ingredients for breakouts and blemishes. A cleanser for this skin needs powerful blemish-fighting ingredients like niacinamide and ceramides, along with hydrating and soothing agents to balance the skin.
Sources: [The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/), [Clinical, Cosmetic and Investigational Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25914553/)

### Which ingredients make this cleanser a good fit for acne-prone skin?

This cleanser works for acne-prone skin because it contains bakuchiol and retinol, which help smooth the skin. However, a product of this type needs targeted ingredients like niacinamide and ceramides to effectively address acne and breakouts.
Sources: [The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/), [Clinical, Cosmetic and Investigational Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25914553/)

### What does Vitamin A do for acne-prone skin?

Vitamin A helps clear acne-prone skin by keeping pores clear and reducing swelling. It works by targeting skin cell growth and calming inflammation.
Sources: [Journal of Drugs in Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35816067/), [Dermatology and Therapy, 2017](https://pubmed.ncbi.nlm.nih.gov/28585191/)

### What does Glycolic Acid do for acne-prone skin?

Glycolic acid helps clear acne-prone skin by reducing pimples and breakouts. It also helps fade dark spots left behind by acne and controls skin oiliness, with very few side effects when used properly.
Sources: [Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33617668/), [Dermatologic Surgery, 2014](https://pubmed.ncbi.nlm.nih.gov/24447110/)

### Where does this cleanser go in a skincare routine for acne-prone skin?

This cleanser goes in both your morning and evening routines as the starting step to wash your face. Because it lacks targeted ingredients for breakouts, a cleanser for this skin needs antibacterial ingredients and soothing extracts to help clear blemishes while keeping your skin calm.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/), [International Journal of Cosmetic Science, 2020](https://pubmed.ncbi.nlm.nih.gov/31461548/)

### Can I use this cleanser with vitamin C, and in what order?

You can use this cleanser with vitamin C by applying the cleanser first and following with your vitamin C product. This cleanser is safe for your skin because it lacks harsh ingredients that could cause irritation.

### How often should I use this cleanser?

You can use this cleanser daily in the morning and evening as part of your routine. Because it contains exfoliating glycolic acid, start by using it just once a week and gradually increase your frequency if your skin tolerates it well.

### Can this cleanser clog pores, cause breakouts or purging for acne-prone skin?

This cleanser is unlikely to cause severe irritation or breakouts since it lacks harsh ingredients, but it does not contain targeted ingredients to effectively clear blemishes on acne-prone skin. A cleanser for this skin needs soothing and blemish-clearing ingredients like salicylic acid or tea tree oil to properly manage breakouts.

### Can I use this cleanser around the eyes or on my body?

You can use this cleanser on your body, but it is best to avoid the very thin skin around your eyes to prevent irritation. Because this formula contains exfoliating ingredients like glycolic acid and retinol, a body wash or cleanser designed for acne-prone skin needs to include soothing agents and targeted blemish-fighting ingredients to properly care for acne.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/), [The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/)

### Is this cleanser fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for acne-prone skin

- [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/ca/p/cerave/foaming-facial-cleanser/for/acne-prone-skin) — Superior fit — CA$20.96 at Amazon
- [Pyunkang Yul Deep Cleansing Foam](https://lovi.care/skincare/ca/p/pyunkang-yul/deep-cleansing-foam/for/acne-prone-skin) — Superior fit — CA$18.79 at Amazon
- [SOME BY MI Snail Truecica Miracle Repair Low pH Gel Cleanser](https://lovi.care/skincare/ca/p/some-by-mi/snail-truecica-miracle-repair-low-ph-gel-cleanser/for/acne-prone-skin) — Superior fit — CA$24.83 at Amazon

## Pairs well with

- Hydrating Toner: [Paula's Choice Resist Advanced Replenishing Toner](https://lovi.care/skincare/ca/p/paula-s-choice/advanced-replenishing-toner/for/acne-prone-skin) — Superior fit — CA$41.00 at Amazon
- Moisturizer: [CeraVe CeraVe PM Facial Moisturizing Lotion](https://lovi.care/skincare/ca/p/cerave/pm-facial-moisturizing-lotion/for/acne-prone-skin) — Superior fit — CA$20.96 at Amazon
- SPF: [innisfree Daily UV Defense Mineral Sunscreen](https://lovi.care/skincare/ca/p/innisfree/daily-uv-defense-mineral-sunscreen/for/acne-prone-skin) — Superior fit — CA$24.50 at Amazon

## Where to buy

No store in Canada has a checked price for this product, so the page shows none.

## Ingredients

Water, Sodium Methyl Cocoyl Taurate, Cocamidopropyl Hydroxysultaine, Cocamidopropyl Betaine, Glyceryl Laurate, Glycolic Acid, Bakuchiol, Retinyl Palmitate Vitamin A, Carica Papaya Fruit Extract, Equisetum Arvense Extract, Macrocystis Pyrifera Extract Kelp Extract, Potassium Sorbate, Phenoxyethanol, Ethylhexylglycerin, Oils
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/derma-e/anti-wrinkle-cleanser/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/derma-e/anti-wrinkle-cleanser/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/derma-e/anti-wrinkle-cleanser/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/derma-e/anti-wrinkle-cleanser/for/acne-prone-skin
- France: https://lovi.care/skincare/fr/p/derma-e/anti-wrinkle-cleanser/for/acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/derma-e/anti-wrinkle-cleanser/for/acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/derma-e/anti-wrinkle-cleanser/for/acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/derma-e/anti-wrinkle-cleanser/for/acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/derma-e/anti-wrinkle-cleanser/for/acne-prone-skin (this page)
- Australia: https://lovi.care/skincare/au/p/derma-e/anti-wrinkle-cleanser/for/acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/derma-e/anti-wrinkle-cleanser/for/acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/derma-e/anti-wrinkle-cleanser/for/acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/derma-e/anti-wrinkle-cleanser/for/acne-prone-skin