d'Alba Piedmont Uvessence Sun Cream for acne-prone skin

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Questions and answers

What the research says

• Liposomal encapsulation of octyl methoxycinnamate increases its safety, skin affinity, and in vivo solar photoprotection factor while slowing its release and enhancing retention in the stratum corneum compared to a conventional formulation.

  International Journal of Nanomedicine, 2013

• Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements.

  Indian Journal of Pharmaceutical Sciences, 2016

• Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components.

  Molecules, 2023

• Chemical sunscreens containing avobenzone, octocrylene, homosalate, and octisalate showed no to minimal risks of dermal irritation, sensitization, photo-allergy, and photo-irritation in human subjects.

  Journal of Drugs in Dermatology, 2025

• The application of a sunscreen formulation containing ethylhexyl methoxycinnamate, ethylhexyl salicylate, methyl anthranilate, and octocrylene does not significantly affect critical acne-related species such as Cutibacterium acnes and Staphylococcus epidermidis, refuting the induction of facial dysbiosis in men.

  Archives of Dermatological Research, 2024

• Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.

  Journal of Cosmetic Dermatology, 2021

• Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.

  The Journal of Investigative Dermatology, 2008

• Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.

  Dermatologic Surgery, 2005

• Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing.

  Journal of Alternative and Complementary Medicine, 2020

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects.

  Journal of Cosmetic Dermatology, 2019

• Topical application of curcumin or turmeric treats various skin conditions by leveraging antioxidant, anti-inflammatory, and antimicrobial properties.

  Skin Pharmacology and Physiology, 2023

• Topical formulations of curcumin target oxidative damage and inflammation to improve wound healing in animal models.

  Drug Discovery Today, 2017

• A curcumin-loaded spanlastic anti-aging gel utilizing formula F5 incorporated into 2% HPMC E50 demonstrated sustained release action, compatibility, and the ability to penetrate skin layers to a depth of about 112.5 um without signs of irritation.

  Saudi Pharmaceutical Journal, 2024

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

• Treatment with Jacquez grapes wine extract protected a three-dimensional tissue culture model of human epidermis against UVB-induced oxidative damage by preventing ROS-mediated alterations.

  Toxicology in Vitro, 2006

• The V. vinifera skin extract (ACH37) scavenged reactive oxygen species, prevented inflammation, modulated extracellular matrix remodeling, increased telomere length and telomerase activity, and reversed UV-induced gene suppression in in vitro and ex vivo assays.

  Journal of Cosmetic Dermatology, 2023

Ingredients

Water, Ethylhexyl Methoxycinnamate, Homosalate, Butylene Glycol, Ethylhexyl Salicylate, Diethylamino Hydroxybenzoyl Hexyl Benzoate, Silica, Ethylhexyl Triazone, Niacinamide, Benzotriazolyl Dodecyl P-Cresol, 1,2-Hexanediol, Caprylyl Methicone, Pentylene Glycol, Salvia Hispanica Seed Extract, Centella Asiatica Extract, Portulaca Oleracea Extract, Houttuynia Cordata Extract, Curcuma Longa Root Extract, Cardiospermum Halicacabum Vine Extract Flower Leaf, Tuber Magnatum Extract, Wine Extract, Citrus Aurantium Dulcis Oil, Citrus Nobilis Peel Oil Mandarin Orange Peel Oil, Echium Plantagineum Seed Oil, Litsea Cubeba Oil Fruit, Helianthus Annuus Seed Oil Sunflower Seed Oil, Polymethylsilsesquioxane, Caprylic Capric Succinic Triglyceride, Ammonium Acryloyldimethyltaurate Vp Copolymer, Propanediol, Saccharide Hydrolysate, Octyldodecanol, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Tromethamine, Hydroxypropyl Methylcellulose Stearoxy Ether, Ethylhexylglycerin, Adenosine, Xylitylglucoside, Anhydroxylitol, Xylitol, Tocopherol, Sodium Pca, Glucose, Limonene, Citral

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.