# Cetaphil Redness Relieving Night Moisturizer for mature skin

**Lovi Fit: High fit for mature skin.**
Normal Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/ca/p/cetaphil/redness-relieving-night-moisturizer/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Brand: [Cetaphil](https://lovi.care/skincare/ca/brands/cetaphil)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/ca/best/moisturizers)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for mature skin; a few moisturizers fit it even better.

## Why this fit

- Highly suitable for your normal skin, this moisturizer effectively hydrates and plumps with glycerin and sodium hyaluronate, while shea butter and sunflower seed oil provide emollient benefits. Although it offers excellent general skincare benefits, it does not specifically target your wrinkles and fine lines.
- The inclusion of allantoin and panthenol further supports skin comfort and barrier function, making it a well-rounded choice for daily use.
- The product is safe for your normal skin, with no risks of irritation due to the absence of harsh ingredients and the presence of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ca/p/cetaphil/redness-relieving-night-moisturizer/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/ca/p/cetaphil/redness-relieving-night-moisturizer/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/ca/p/cetaphil/redness-relieving-night-moisturizer/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/ca/p/cetaphil/redness-relieving-night-moisturizer/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/ca/p/cetaphil/redness-relieving-night-moisturizer/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/ca/p/cetaphil/redness-relieving-night-moisturizer/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/ca/p/cetaphil/redness-relieving-night-moisturizer/for/mature-skin): High (this page)
- [Dry sensitive skin](https://lovi.care/skincare/ca/p/cetaphil/redness-relieving-night-moisturizer/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/ca/p/cetaphil/redness-relieving-night-moisturizer/for/oily-acne-prone-skin): Average

## Key ingredients

Allantoin, Niacinamide, Panthenol Vitamin B5, Tocopheryl Acetate Vitamin E, Ceramide Np

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/))
- Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016](https://pubmed.ncbi.nlm.nih.gov/27475700/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment. ([Aesthetic Plastic Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29948103/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans. ([Arzneimittel-Forschung, 2000](https://pubmed.ncbi.nlm.nih.gov/10965426/))
- Hyaluronic acid, hyaluronic acid plus dexpanthenol, and isotonic saline nasal sprays all significantly improved dry nose symptoms over four weeks in 240 patients, with hyaluronic acid plus dexpanthenol providing superior nasal moisturisation compared to the other two. ([Auris, Nasus, Larynx, 2020](https://pubmed.ncbi.nlm.nih.gov/32067777/))
- Topical application of an antioxidant serum containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented particulate matter-induced degradation of extracellular matrix components, inflammation, and oxidative stress in the skin of 15 female volunteers compared to untreated controls. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40642809/))
- Dermatological products containing d-alpha tocopheryl acetate showed non-comedogenic potential with less than a 50% increase in microcomedones in 12 healthy male subjects compared to octyl palmitate. ([Contemporary Clinical Trials Communications, 2021](https://pubmed.ncbi.nlm.nih.gov/34471722/))
- Topical application of an antioxidant mix containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented PM and UV-induced skin barrier perturbation, lipid peroxidation, inflammatory markers, MMP9 activation, and Type I collagen loss in 15 healthy females compared to untreated exposed skin. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38590207/))

## What reviewers say

Many users report a visible reduction in redness and a calmer complexion by morning. A subset of reviewers find it functions better as a gentle maintenance moisturizer rather than a treatment that actively eliminates existing redness.

- Liked: Gentle & soothing (often mentioned)
- Liked: Lightweight texture (often mentioned)
- Liked: Reduces redness (often mentioned)
- Liked: Fragrance-free (sometimes noted)
- Liked: Hydrating (sometimes noted)
- Disliked: Ineffective on redness (sometimes noted)
- Disliked: Caused irritation (rarely noted)
- Disliked: Packaging issues (rarely noted)
- Disliked: Small quantity (rarely noted)
- Disliked: Texture too thin (rarely noted)

## How to apply

- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help smooth fine lines.
- Apply this product after your toner and serum, but before your SPF in the morning. Follow your cleanser and toner steps to keep your skin balanced.
- Gently press a small amount into your face and neck. Avoid rubbing the skin too harshly to prevent extra tension.
- Apply the moisturizer on slightly damp skin to help lock in extra moisture. Clean skin helps the product absorb much more evenly.
- Avoid the sensitive eye area during application. Do a quick patch test before your very first use to stay safe.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes Cetaphil Redness Relieving Night Moisturizer a great fit for mature skin?

This moisturizer is a great fit because glycerin and sodium hyaluronate hydrate and plump the skin, while shea butter and sunflower seed oil smooth it. Allantoin and panthenol also help keep the skin calm and support its protective barrier.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Which ingredients make this cream a good fit for mature skin?

This cream is a good fit for mature skin because it contains glycerin, sodium hyaluronate, shea butter, and sunflower seed oil to effectively hydrate and keep skin soft. It also includes allantoin, panthenol, and ceramide NP to support skin comfort and help maintain the moisture barrier.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### What does Allantoin do for mature skin?

Allantoin helps soothe dry and irritated mature skin while supporting a smooth and healthy skin barrier. This ingredient may improve overall skin softness and comfort, making it a helpful addition to daily anti-aging routines.
Sources: [Pharmaceutics, 2026](https://pubmed.ncbi.nlm.nih.gov/41900878/), [Journal of Functional Biomaterials, 2021](https://pubmed.ncbi.nlm.nih.gov/34842756/)

### What does Niacinamide do for mature skin?

Niacinamide helps mature skin by smoothing out fine lines and wrinkles, reducing dark spots, and improving overall skin elasticity. It is also very well tolerated and supports a strong skin barrier to keep skin looking healthy.
Sources: [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/), [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/)

### Where does this cream go in a skincare routine for mature skin?

This cream goes last in your evening routine and before sunscreen in the morning, serving as your daily moisturizer. It helps lock in hydration and supports skin comfort with ingredients like glycerin, ceramides, and panthenol.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use this cream with retinol, and in what order?

You can use this cream with retinol, applying the retinol first and following with this moisturizer to keep your skin calm and hydrated. Barrier-supporting moisturizers like this one are well-suited to help reduce the dryness and irritation that often come with using retinol.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22648223/)

### How often should I use this cream?

This cream is a great fit for your mature skin and can be used daily as part of your morning and evening routines. Daily use helps keep skin hydrated and comfortable while supporting your skin barrier.
Sources: [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/), [Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/14571069/)

### Can this cream clog pores, cause breakouts or purging for mature skin?

This cream is unlikely to clog pores or cause breakouts for mature skin, as it has a safe profile with soothing ingredients and no harsh components. It helps keep skin comfortable without causing irritation.
Sources: [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Can I use this cream around the eyes or on my body?

You can use this cream on your body and around the eyes because its gentle formula and nourishing ingredients are safe for delicate skin. The eyelid is among the thinnest areas of skin on the body, making a soothing moisturizer like this a comfortable choice for these regions.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetearyl alcohol, behenyl alcohol, and cetyl alcohol are fatty alcohols, which soften the skin.

## Alternatives for mature skin

- [Obagi Hydrate Luxe Moisture-Rich Cream](https://lovi.care/skincare/ca/p/obagi/hydrate-luxe/for/mature-skin) — Superior fit — CA$103.73 at Amazon
- [SKIN1004 Madagascar Centella Probio-Cica Enrich Cream](https://lovi.care/skincare/ca/p/skin1004/madagascar-centella-probio-cica-enrich-cream/for/mature-skin) — Superior fit — CA$30.98 at Amazon
- [L'Occitane Immortelle Divine Cream](https://lovi.care/skincare/ca/p/l-occitane/immortelle-divine-cream/for/mature-skin) — Superior fit — CA$199.19 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/ca/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — CA$44.95 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/ca/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — CA$31.98 at Amazon
- SPF: [Torriden DIVE-IN Mild Sunscreen](https://lovi.care/skincare/ca/p/torriden/dive-in-mild-sunscreen/for/mature-skin) — Superior fit — CA$27.34 at Amazon

## Where to buy

No store in Canada has a checked price for this product, so the page shows none.

## Ingredients

Water, Caprylic Capric Triglyceride, Glycerin, Propanediol, Pentylene Glycol, Helianthus Annuus Seed Oil Sunflower Seed Oil, Sorbitol, Dimethicone, Butyrospermum Parkii Butter Shea Butter, Cetearyl Alcohol, Behenyl Alcohol, Glyceryl Stearate, Sodium Hydroxide, Tocopheryl Acetate, Allantoin, Dipotassium Glycyrrhizate, Sodium Hyaluronate, Ceramide Np, Panthenol, Caffeine, Citric Acid, Cetyl Alcohol, Ceteareth-20, Glyceryl Stearate Citrate, Disodium Ethylene Dicocamide Peg-15 Disulfate, Niacinamide, Caprylyl Glycol, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Disodium Edta, Xanthan Gum, Bht
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/cetaphil/redness-relieving-night-moisturizer/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/cetaphil/redness-relieving-night-moisturizer/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/cetaphil/redness-relieving-night-moisturizer/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/cetaphil/redness-relieving-night-moisturizer/for/mature-skin
- France: https://lovi.care/skincare/fr/p/cetaphil/redness-relieving-night-moisturizer/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/cetaphil/redness-relieving-night-moisturizer/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/cetaphil/redness-relieving-night-moisturizer/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/cetaphil/redness-relieving-night-moisturizer/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/cetaphil/redness-relieving-night-moisturizer/for/mature-skin (this page)
- Australia: https://lovi.care/skincare/au/p/cetaphil/redness-relieving-night-moisturizer/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/cetaphil/redness-relieving-night-moisturizer/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/cetaphil/redness-relieving-night-moisturizer/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/cetaphil/redness-relieving-night-moisturizer/for/mature-skin