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Biossance 100% Squalane Oil for combination skin

Biossance 100% Squalane Oil
  • Squalane
  • Squalane Oil

Average

  • AverageCombination Skin Fit
  • AverageEffectiveness
  • ConcerningSafety

Works for combination skin; other products fit it better.

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.

Page built Nov 8, 2026How the Fit score works

Lovi Assistant explains

  • Offers moderate moisturizing for your combination skin, as squalane provides emollient action to hydrate and enhance barrier resilience, though it lacks sufficient humectant ingredients to fully address your oily shine.
  • This formula provides general skincare benefits that are mostly supportive for your combination skin type.

People Say

★4.7Overall rating based on 2.5k+ reviews

This sugarcane-derived oil is widely praised as a "holy grail" for its lightweight, non-greasy texture that mimics the skin's natural moisture. Users with sensitive and acne-prone skin frequently report that it hydrates without clogging pores, while many appreciate its versatility as a multi-purpose treatment for face, body, and hair. This summary is based on a very large amount of data and should definitely be taken into account.

Highlights

  • Lightweight non-greasy Mostly Mentioned
    • “soaks in right away”
    • “doesn't feel heavy”
    • “leaves a nice glow not grease”
    • “feels like nothing on skin”
  • Multi-purpose versatility Often Mentioned
    • “tames frizzy hair”
    • “great on dry cuticles”
    • “mixes well with foundation”
    • “healed cracked elbows”
  • Softens skin texture Often Mentioned
    • “skin feels like velvet”
    • “plumps fine lines”
    • “makes face super soft”
    • “got rid of dry patches”
  • Soothing gentle Sometimes Noted
    • “stopped the flaking”
    • “no stinging on sensitive skin”
    • “safe for fungal acne”
  • Packaging pump issues Sometimes Noted
    • “pump leaks everywhere”
    • “dispenses too much product”
    • “messy cap”
    • “bottle gets oily”
  • Caused breakouts Rarely Noted
    • “gave me cystic acne”
    • “caused tiny whiteheads”
    • “clogged my pores”
    • “rash appeared after use”
  • Insufficient hydration Rarely Noted
    • “sat on top of skin”
    • “still felt dry later”
    • “needed a cream over it”
    • “too thin for winter”
  • Price point Rarely Noted
    • “pricy for just squalane”
    • “The Ordinary is cheaper”
    • “not worth the splurge”
    • “paying for the brand”

Sources: lovi.care, biossance.com, sephora.ph, kohls.com, influenster.com, sephora.com, and more

Questions and answers

How well does Biossance 100% Squalane Oil work for combination skin?

Biossance 100% Squalane Oil is an average fit for your combination skin because it provides moderate moisture and helps strengthen your skin barrier, but it lacks enough water-attracting ingredients to fully handle oily shine. To work best for combination skin, a product of this type needs effective brightening and moisturizing ingredients to reduce oily shine, along with soothing agents, antioxidants, and multiple peptides.

Molecules, 2025Scientific Reports, 2020

Which ingredients make this oil a good fit for combination skin?

Squalane and Squalane Oil make this oil work for your combination skin by giving it moderate moisture and strengthening your skin barrier. To be a better fit for this skin type, a product of this type needs brightening ingredients and water-attracting ingredients that reduce oily shine without irritation.

Molecules, 2025Scientific Reports, 2020

What does Squalane do for combination skin?

Squalane helps keep combination skin soft and smooth by locking in moisture without feeling heavy or greasy. It supports the skin barrier and provides lightweight hydration that works well for both dry and oily areas.

Skin Health and Disease, 2024Journal of Nanobiotechnology, 2025

What does Squalane Oil do for combination skin?

Squalane oil helps keep combination skin soft and smooth without feeling heavy or greasy. It supports your skin barrier and provides lightweight moisture that balances dry and oily areas.

International Journal of Molecular Sciences, 2017

Where does this oil go in a skincare routine for combination skin?

Biossance 100% Squalane Oil goes near the end of your routine to lock in moisture and support your skin barrier. Because it provides moderate moisture without enough water-drawing ingredients to handle oily shine, combination skin also needs hydrating ingredients like glycerin or hyaluronic acid to stay balanced.

Molecules, 2025Scientific Reports, 2020

Can I use this oil with retinol, and in what order?

You can use this oil with retinol by applying the oil after your retinol to help keep your skin soft and comfortable. This type of skin also needs ingredients that pull in moisture to fully control oily shine.

Cutis, 2006

How often should I use this oil?

You can use this oil daily as part of your morning or evening routine to help keep your combination skin soft and moisturized. Because it lacks ingredients that draw in moisture, a combination skin type like yours also needs hydrating ingredients to fully balance oily shine.

Molecules, 2025Scientific Reports, 2020

Can this oil clog pores, cause breakouts or purging for combination skin?

Biossance 100% Squalane Oil is unlikely to cause breakouts for combination skin, though reviewers mention a low risk of pimples. This oil keeps your skin soft and smooth, but a product of this type needs extra water-attracting ingredients to properly hydrate combination skin while managing oily shine.

What the research says

  • Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts.

    Molecules, 2025
  • Topical application of a vitamin C-squalene bioconjugate significantly increased epidermal thickness, type III collagen production, and glycosaminoglycans production in human skin explants compared to free vitamin C and vitamin C-palmitate.

    Scientific Reports, 2020
  • Application of squalene/phosphotungstate calcium nanowires (Sql/PWC) oleogel on UVB-irradiated skin decreased epidermal thickness, increased dermal thickness, and promoted the expression of elastin, collagen, and skin barrier markers through antioxidant and anti-inflammatory activities.

    Journal of Nanobiotechnology, 2025
  • Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway.

    Antioxidants, 2025

Ingredients

Squalane, Squalane Oil

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

How does it fit your skin?

Scan your face, then any product.

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Prices checked 10 Oct 2026

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

How does it fit your skin?

Scan your face, then any product: Lovi shows how well it fits you and what fits even better.