# Bioderma Pigmentbio Sensitive Areas for mature skin

**Lovi Fit: Average fit for mature skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: Excellent.

Page: https://lovi.care/skincare/ca/p/bioderma/pigmentbio-sensitive-areas/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Brand: [Bioderma](https://lovi.care/skincare/ca/brands/bioderma)
Category: [Serums and treatments](https://lovi.care/skincare/ca/best/serums)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for mature skin; other serums fit it better.

## Why this fit

- Offers moderate brightening and evening of skin tone for your normal skin, as azelaic acid and licorice root extract target hyperpigmentation while salicylic acid and azelaic acid provide keratolytic action and melanogenesis regulation.
- Glycerin and dimethicone offer hydration and soothing benefits, which are supportive but not directly addressing your primary concern of wrinkles and fine lines.
- The product is safe for your normal skin, with no risks of irritation due to the absence of harsh ingredients and the inclusion of soothing agents like licorice root extract and tocopherol.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ca/p/bioderma/pigmentbio-sensitive-areas/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/ca/p/bioderma/pigmentbio-sensitive-areas/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/ca/p/bioderma/pigmentbio-sensitive-areas/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/ca/p/bioderma/pigmentbio-sensitive-areas/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/ca/p/bioderma/pigmentbio-sensitive-areas/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/ca/p/bioderma/pigmentbio-sensitive-areas/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/ca/p/bioderma/pigmentbio-sensitive-areas/for/mature-skin): Average (this page)
- [Dry sensitive skin](https://lovi.care/skincare/ca/p/bioderma/pigmentbio-sensitive-areas/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/ca/p/bioderma/pigmentbio-sensitive-areas/for/oily-acne-prone-skin): High

## Key ingredients

Azelaic Acid, Licorice Root Extract, Salicylic Acid, Andrographis Paniculata Leaf Extract, Laminaria Ochroleuca Extract

## What the research says

- Application of 15% azelaic acid gel significantly reduced post-inflammatory erythema and hyperpigmentation, decreased hemoglobin and melanin content, improved quality of life, and contributed to acne improvement in patients with mild to moderate acne compared to placebo. ([Dermatology and Therapy, 2024](https://pubmed.ncbi.nlm.nih.gov/38734843/))
- A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/))
- Azelaic acid nanocrystal hydrogel 10% achieved a higher success rate and greater lesion reduction than azelaic acid cream 20% in patients with mild to moderate facial acne. ([Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/))
- Topical application of a dermocosmetic containing Myrtus communis extract and azelaic acid reduced acne relapses and helped maintain remission compared to a light moisturizing cream in adult females in the acne maintenance phase over 16 weeks. ([Journal of the European Academy of Dermatology and Venereology, 2023](https://pubmed.ncbi.nlm.nih.gov/36729399/))
- Topical administration of 20% azelaic acid cream and 5% tranexamic acid solution comparably improved acne-related postinflammatory hyperpigmentation in patients with acne vulgaris, while tranexamic acid demonstrated a significantly better safety profile at week 4. ([Journal of Research in Medical Sciences, 2023](https://pubmed.ncbi.nlm.nih.gov/37213446/))
- Combining 755 nm alexandrite laser with topical licorice gel significantly reduces terminal hair counts compared to alexandrite laser with placebo in women with idiopathic hirsutism. ([Evidence-based Complementary and Alternative Medicine, 2015](https://pubmed.ncbi.nlm.nih.gov/26273313/))
- Licochalcone A activated Nrf2 signaling, elevated cytoprotective enzymes, increased the reduced-to-oxidized glutathione ratio, and decreased reactive oxygen species in human fibroblasts and neutrophils, while a LicA-rich licorice extract lowered UVA-induced oxidative processes in vivo. ([Experimental Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25381913/))
- Bioactive glycyrrhizic acid and oxymatrine ionic liquid self-assembled nanomicelles significantly promoted the transdermal permeation, subcutaneous retention, and anti-photoaging efficacy of palmitoyl pentapeptide-4 in cellular and animal models compared to unformulated peptide. ([Advanced Science, 2025](https://pubmed.ncbi.nlm.nih.gov/39783908/))
- Cryotherapy with liquid nitrogen achieved a higher cure rate (39%) than salicylic acid (24%) and a wait-and-see approach (16%) for cutaneous warts at 13 weeks in primary care patients. ([CMAJ, 2010](https://pubmed.ncbi.nlm.nih.gov/20837684/))
- A moisturizer containing licochalcone A, 1,2-decanediol, L-carnitine, and salicylic acid significantly reduced noninflammatory, inflammatory, and total acne lesion counts compared to a vehicle control in Thai patients during a 12-week maintenance phase. ([BioMed Research International, 2020](https://pubmed.ncbi.nlm.nih.gov/33150170/))
- Treatment with 2% supramolecular salicylic acid hydrogel resulted in a regression and markedly improvement rate of 51.01% compared to 43.10% for Adapaline gel in patients with mild to moderate facial acne vulgaris, showing no significant difference in efficacy. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38590107/))
- An Andrographis paniculata extract promoted epidermal stem cell proliferation, up-regulated integrin beta1 and vascular endothelial growth factor expression, enhanced collagen production, and improved skin hydration, dermal density, wrinkling, and sagging in clinical evaluation. ([Molecules, 2015](https://pubmed.ncbi.nlm.nih.gov/26402665/))
- Combined treatment of andrographolide and Bidens pilosa extract activated RXR alpha, enhanced extracellular matrix protein gene expression with antioxidant and anti-inflammatory efficacies, and improved wrinkles, skin elasticity, and hydration without causing irritating side effects in human subjects. ([Biomolecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40001599/))
- Topical administration of andrographolide sodium bisulfate prevented UV-induced skin photoaging in mice by increasing collagen content, reducing epidermal thickness and MDA levels, upregulating SOD and CAT activities, and downregulating IL-1β, IL-6, IL-10, and TNF-α production compared to UV-irradiated mice without ASB. ([Mediators of Inflammation, 2016](https://pubmed.ncbi.nlm.nih.gov/26903706/))

## Why other serums fit mature skin better

- Topical application of retinol and retinoic acid both increased epidermal thickness and upregulated collagen genes and proteins in human skin, with retinol producing similar histological and molecular changes to retinoic acid alongside a significant reduction in facial wrinkles after 12 weeks. ([Journal of Cosmetic Dermatology, 2016](https://pubmed.ncbi.nlm.nih.gov/26578346/))
- A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/))

## What reviewers say

Based on limited data, this product is highly praised for its ability to gently fade hyperpigmentation and dark spots in delicate areas. Users with sensitive skin appreciate its soothing, non-irritating, and hydrating formula, though some note that achieving visible lightening outcomes requires consistent, long-term application.

- Liked: Fades dark spots (often mentioned)
- Liked: Gentle on skin (often mentioned)
- Liked: Absorbs very quickly (sometimes noted)
- Liked: Hydrating and moisturizing (sometimes noted)
- Disliked: Slow visible results (sometimes noted)
- Disliked: Half empty tubes (rarely noted)
- Disliked: Poor packaging design (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week, and work up to daily use if your skin likes it.
- Apply this serum after your toner and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- You can apply the serum on dry skin for the best results against fine lines.
- Always do a patch test before your first use and avoid the sensitive eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Pigmentbio Sensitive Areas work for mature skin?

Bioderma Pigmentbio Sensitive Areas works moderately well for mature skin by evening out skin tone and providing hydration and soothing benefits, though it is not primarily targeted at wrinkles and fine lines. To better fit mature skin, a product of this type needs high-quality anti-aging ingredients, potent antioxidants, and skin-repairing components that effectively target wrinkles and fine lines.

### Which ingredients make this cream a good fit for mature skin?

Glycerin and dimethicone provide hydration and soothing benefits, but this treatment is an average fit for mature skin because it does not directly target wrinkles and fine lines. A product of this type needs potent antioxidants, hydrating components, and skin-repairing ingredients to properly care for mature skin.

### What does Azelaic Acid do for mature skin?

Azelaic acid helps mature skin by targeting dark spots and uneven tone, while supporting smoother texture and a more youthful look. It provides antioxidant benefits that may reduce signs of aging and protect skin from environmental stress.
Sources: [Frontiers in Medicine, 2026](https://pubmed.ncbi.nlm.nih.gov/42023095/), [Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/36056802/)

### What does Licorice Root Extract do for mature skin?

Licorice Root Extract helps calm mature skin and may reduce dark spots and redness. It contains antioxidants that protect skin from daily stress and support a more even, bright, and smooth look.
Sources: [Experimental Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25381913/)

### Where does this cream go in a skincare routine for mature skin?

This treatment goes in the evening routine after cleansing and toning, and before moisturizing. Because this is an average fit for mature skin, a product of this type needs firming ingredients and antioxidants like peptides and vitamins to properly target wrinkles and fine lines.

### Can I use this cream with retinol, and in what order?

You can use this treatment with retinol by applying retinol first and this cream after, but mature skin needs products with powerful peptides and antioxidants to target wrinkles and firmness.

### How often should I use this cream?

You can use this treatment in the evening as part of your routine. Products of this type for mature skin need ingredients that help smooth fine lines and boost firmness, such as retinoids or peptides.

### Can this cream clog pores, cause breakouts or purging for mature skin?

This treatment is unlikely to clog pores or cause breakouts on mature skin, as it has a safe profile with no harsh ingredients. However, because it is an average fit for this skin type, mature skin typically needs products with rich hydrators and firming ingredients to properly target wrinkles and fine lines.

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for mature skin

- [Dr.Althea Vitamin C Boosting Serum](https://lovi.care/skincare/ca/p/dr-althea/vitamin-c-boosting-serum/for/mature-skin) — High fit — CA$27.99 at Amazon
- [The Ordinary Matrixyl 10% + HA](https://lovi.care/skincare/ca/p/the-ordinary/matrixyl-10-ha/for/mature-skin) — High fit — CA$14.40 at Amazon
- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/ca/p/skin1004/probio-cica-intensive-ampoule/for/mature-skin) — High fit — CA$24.44 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/ca/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — CA$44.95 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/ca/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — CA$31.98 at Amazon
- Moisturizer: [Obagi Hydrate Luxe Moisture-Rich Cream](https://lovi.care/skincare/ca/p/obagi/hydrate-luxe/for/mature-skin) — Superior fit — CA$103.73 at Amazon

## Where to buy

- Amazon.ca: CA$47.99 (https://www.amazon.ca/dp/B09231D8X3?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- Shoppers Drug Mart: CA$47.99 (https://www.shoppersdrugmart.ca/bioderma-pigmentbio-sensitive-areas/p/BB_3701129800096?variantCode=3701129800096)
Prices checked 10 Oct – 2 Nov 2026.

## Ingredients

Water, Glycerin, Cetyl Alcohol, Dimethicone, Polymethylsilsesquioxane, Dipropylene Glycol, Propylheptyl Caprylate, Caprylic Capric Triglyceride, Hdi Trimethylol Hexyllactone Crosspolymer, C14-22 Alcohols, Pentylene Glycol, Carbomer, Polysilicone-11, Caprylyl Glycol, 1,2-Hexanediol, Ammonium Acryloyldimethyltaurate Vp Copolymer, Butylene Glycol, Disodium Edta, Lysine, C12-20 Alkyl Glucoside, Azelaic Acid, Laminaria Ochroleuca Extract, Mannitol, Salicylic Acid, Xylitol, Andrographis Paniculata Leaf Extract, Rhamnose, Sodium Hydroxide, Glycyrrhiza Glabra Root Extract Licorice Root Extract, Decyl Glucoside, Fructooligosaccharides, Tocopherol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/bioderma/pigmentbio-sensitive-areas/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/bioderma/pigmentbio-sensitive-areas/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/bioderma/pigmentbio-sensitive-areas/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/bioderma/pigmentbio-sensitive-areas/for/mature-skin
- France: https://lovi.care/skincare/fr/p/bioderma/pigmentbio-sensitive-areas/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/bioderma/pigmentbio-sensitive-areas/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/bioderma/pigmentbio-sensitive-areas/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/bioderma/pigmentbio-sensitive-areas/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/bioderma/pigmentbio-sensitive-areas/for/mature-skin (this page)
- Australia: https://lovi.care/skincare/au/p/bioderma/pigmentbio-sensitive-areas/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/bioderma/pigmentbio-sensitive-areas/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/bioderma/pigmentbio-sensitive-areas/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/bioderma/pigmentbio-sensitive-areas/for/mature-skin