# BASE LABORATORIES Hypochlorous Acid Spray for mature skin

**Lovi Fit: Average fit for mature skin.**
Normal Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/ca/p/base-laboratories/hypochlorous-acid-spray/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Brand: [BASE LABORATORIES](https://lovi.care/skincare/ca/brands/base-laboratories)
Category: [Serums and treatments](https://lovi.care/skincare/ca/best/serums)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for mature skin; other serums fit it better.

## Why this fit

- Offers moderate treatment for acne-prone skin due to the presence of hypochlorous acid in moderate concentrations for reducing acne lesions and blemishes.
- It provides general skincare benefits, such as cleansing, but lacks specialized ingredients targeting wrinkles and fine lines, which is your main goal.
- The safety profile is excellent, with no risks of irritation for your normal skin due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ca/p/base-laboratories/hypochlorous-acid-spray/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/ca/p/base-laboratories/hypochlorous-acid-spray/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/ca/p/base-laboratories/hypochlorous-acid-spray/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/ca/p/base-laboratories/hypochlorous-acid-spray/for/sensitive-skin): Superior
- [Acne-prone skin](https://lovi.care/skincare/ca/p/base-laboratories/hypochlorous-acid-spray/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/ca/p/base-laboratories/hypochlorous-acid-spray/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/ca/p/base-laboratories/hypochlorous-acid-spray/for/mature-skin): Average (this page)
- [Dry sensitive skin](https://lovi.care/skincare/ca/p/base-laboratories/hypochlorous-acid-spray/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/ca/p/base-laboratories/hypochlorous-acid-spray/for/oily-acne-prone-skin): High

## Key ingredients

Hypochlorous Acid, Sodium Chloride

## What the research says

- Pure hypochlorous acid cleansing solution significantly reduced bacterial growth and resulted in fewer wound-related complications compared to saline, soap and water, or standard of care in 2968 wounds across 2682 patients. ([Journal of Wound Care, 2026](https://pubmed.ncbi.nlm.nih.gov/42842699/))
- Topical 0.01% hypochlorous acid through ultrasonic atomization significantly improved OSDI scores, lid margin redness, lid margin abnormality, meibum expressibility, and meibum quality compared to control eyelid scrubs in patients with blepharitis after 2 weeks. ([Journal of Clinical Medicine, 2023](https://pubmed.ncbi.nlm.nih.gov/36769811/))
- A sporicidal hypochlorous acid solution (Vashe) safely and significantly enhanced the reduction of Clostridium difficile spores and Bacillus anthracis surrogates from human skin compared to soap and water. ([PloS One, 2013](https://pubmed.ncbi.nlm.nih.gov/23844234/))
- Daily application of an acid-oxidising solution containing hypochlorous acid to chronic epidermolysis bullosa wounds reduced Staphylococcus aureus relative abundance from 34% to 10% at 8 weeks, increased bacterial diversity, and diminished wound sizes in 15 patients. ([Experimental Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40803690/))
- Calcium hydroxylapatite diluted with normal saline combined with microfocused ultrasound with visualization improved age-related changes in the lower face, neck, and décolleté and stimulated collagen and elastin fibers in 20 subjects. ([Journal of Drugs in Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32272518/))
- Hyaluronic acid, hyaluronic acid plus dexpanthenol, and isotonic saline nasal sprays all significantly improved dry nose symptoms over four weeks in 240 patients, with hyaluronic acid plus dexpanthenol providing superior nasal moisturisation compared to the other two. ([Auris, Nasus, Larynx, 2020](https://pubmed.ncbi.nlm.nih.gov/32067777/))
- Topical application of magnetized saline water serum improved skin hydration, reduced transepidermal water loss, sebum content, melanin index, and erythema index, and activated autophagy by increasing Beclin-1 and decreasing mTOR in females wanting to enhance facial and neck skin appearance. ([Cureus, 2023](https://pubmed.ncbi.nlm.nih.gov/38130575/))

## Why other serums fit mature skin better

- Twice-daily application of LR2412-Cx significantly improved fine wrinkles, texture, and pores in 15 subjects over 6 weeks without significant untoward effects. ([Journal of Drugs in Dermatology, 2016](https://pubmed.ncbi.nlm.nih.gov/26885790/))
- Apigenin protects against UVA-induced cytotoxicity and senescence in normal human dermal fibroblasts, decreases MMP-1 expression, and when applied topically as a cream in human subjects, increases dermal density and elasticity while reducing fine wrinkle length, skin evenness, moisture content, and transepidermal water loss compared to control cream. ([International Journal of Molecular Medicine, 2016](https://pubmed.ncbi.nlm.nih.gov/27279007/))
- A Hamamelis virginiana leaf extract increased LOXL1 expression twofold, decreased elafin synthesis, restored functional elastic fibers, reduced nonfunctional elastin aggregates, decreased wrinkles, and improved skin firmness. ([Journal of Cosmetic Science, 2018](https://pubmed.ncbi.nlm.nih.gov/30052192/))

## What reviewers say

Many appreciate the fine mist and soothing properties, though some users note a distinct chlorine scent and a slightly heavier residue compared to pure hypochlorous acid brands due to added ingredients.

- Liked: Calms irritation (mostly mentioned)
- Liked: Great value (often mentioned)
- Liked: Soothing and gentle (often mentioned)
- Liked: Fine mist spray (sometimes noted)
- Disliked: Chlorine scent (sometimes noted)
- Disliked: Added ingredients (rarely noted)
- Disliked: Packaging issues (rarely noted)
- Disliked: Residue or heavy (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week, and work up to daily use if your skin likes it.
- Apply this serum after your toner and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- You can apply the serum on dry skin for the best results against fine lines.
- Always do a patch test before your first use and avoid the sensitive eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Base Laboratories Hypochlorous Acid Spray work for mature skin?

Base Laboratories Hypochlorous Acid Spray is an average fit for mature skin because it cleanses gently and is very safe, but it lacks the specialized ingredients needed to target wrinkles and fine lines. A product of this type needs effective hydrating and soothing ingredients, like aloe, chamomile, or plant oils, to deliver the best anti-aging results for mature skin.
Sources: [Journal of Wound Care, 2026](https://pubmed.ncbi.nlm.nih.gov/42842699/)

### Which ingredients make this spray a good fit for mature skin?

Hypochlorous acid is the main active ingredient that helps cleanse and calm the skin. However, since mature skin needs extra help with wrinkles and fine lines, a product of this type needs specialized hydrating and soothing ingredients to be a great fit.
Sources: [Journal of Wound Care, 2026](https://pubmed.ncbi.nlm.nih.gov/42842699/)

### What does Hypochlorous Acid do for mature skin?

Hypochlorous acid helps calm irritated or inflamed skin and fights bacteria to keep skin clear and healthy. It is generally very safe and unlikely to cause irritation, making it a gentle option for sensitive skin types.
Sources: [The Journal of Clinical and Aesthetic Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588272/), [Biomedicines, 2025](https://pubmed.ncbi.nlm.nih.gov/41462936/)

### What does Water do for mature skin?

Water helps keep mature skin hydrated, which significantly lowers the severity of wrinkles and maintains elasticity. Because aging skin often loses moisture and firmness, it needs hydrating ingredients like glycerin and hyaluronic acid to stay plump and smooth.
Sources: [Skin Research and Technology, 2013](https://pubmed.ncbi.nlm.nih.gov/22672420/)

### Where does this spray go in a skincare routine for mature skin?

This spray fits into your evening routine as a treatment step, used in the PM or weekly after cleansing. While it cleanses and helps with blemishes safely on normal skin, a product for mature skin needs specialized ingredients targeting wrinkles and fine lines.

### Can I use this spray with retinol, and in what order?

You can use this spray alongside retinol, applying the spray first and letting it dry completely before putting on your retinol. This spray is unlikely to irritate normal skin due to its very safe ingredients, but mature skin needs a product with specialized ingredients targeting wrinkles and fine lines.

### How often should I use this spray?

You can use this spray in your evening routine as a treatment, and it is very safe and unlikely to cause irritation for your normal skin. However, since it lacks specialized ingredients for your mature skin, a product of this type needs added antioxidants, retinols, and moisturizers to properly smooth wrinkles and fine lines.
Sources: [Facial Plastic Surgery, 2014](https://pubmed.ncbi.nlm.nih.gov/24488631/)

### Can this spray clog pores, cause breakouts or purging for mature skin?

This spray is unlikely to clog pores or cause breakouts on mature skin because it has a safe formula without harsh or heavy ingredients that typically cause congestion. However, a product for this skin type needs specialized ingredients targeting wrinkles and fine lines to truly match your main goal.
Sources: [Journal of Wound Care, 2026](https://pubmed.ncbi.nlm.nih.gov/42842699/)

## Alternatives for mature skin

- [Mario Badescu Facial Spray with Aloe, Chamomile and Lavender](https://lovi.care/skincare/ca/p/mario-badescu/facial-spray-with-aloe-chamomile-and-lavender/for/mature-skin) — High fit — CA$35.46 at Amazon
- [Vichy Mineralizing Thermal Water](https://lovi.care/skincare/ca/p/vichy/mineralizing-thermal-water/for/mature-skin) — High fit — CA$12.95 at Amazon
- [MEDIHEAL Tea Tree Biome Blemish Cica Pad](https://lovi.care/skincare/ca/p/mediheal/tea-tree-biome-blemish-cica-pad/for/mature-skin) — High fit — CA$32.38 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/ca/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — CA$44.95 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/ca/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — CA$31.98 at Amazon
- Moisturizer: [Obagi Hydrate Luxe Moisture-Rich Cream](https://lovi.care/skincare/ca/p/obagi/hydrate-luxe/for/mature-skin) — Superior fit — CA$103.73 at Amazon

## Where to buy

- Amazon.ca: CA$24.95 (https://www.amazon.ca/dp/B0BR666F2L?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
Prices checked 2 Nov 2026.

## Ingredients

Water, Sodium Chloride, Hypochlorous Acid
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/base-laboratories/hypochlorous-acid-spray/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/base-laboratories/hypochlorous-acid-spray/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/base-laboratories/hypochlorous-acid-spray/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/base-laboratories/hypochlorous-acid-spray/for/mature-skin
- France: https://lovi.care/skincare/fr/p/base-laboratories/hypochlorous-acid-spray/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/base-laboratories/hypochlorous-acid-spray/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/base-laboratories/hypochlorous-acid-spray/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/base-laboratories/hypochlorous-acid-spray/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/base-laboratories/hypochlorous-acid-spray/for/mature-skin (this page)
- Australia: https://lovi.care/skincare/au/p/base-laboratories/hypochlorous-acid-spray/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/base-laboratories/hypochlorous-acid-spray/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/base-laboratories/hypochlorous-acid-spray/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/base-laboratories/hypochlorous-acid-spray/for/mature-skin